Pretreatment Immature Platelet Fraction as a Surrogate of Reticulated Platelets Predicts the Response to Corticosteroids in Adults with Immune Thrombocytopenia.

abstract：:In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and pro...

journal_title：Acta haematologica

authors： Bhargava M,Sanyal SK,Thapar MK,Kumar S,Hooja V

更新日期：1976-01-01 00:00:00

abstract：:This paper reports the bone marrow histological picture in 7 patients with hairy cell leukemia treated with recombinant interferon. Bone marrow biopsies were performed at diagnosis, after 1, 3 and 7 months from the beginning of treatment and at 12 months at treatment suspension. The main modifications observed were a ...

journal_title：Acta haematologica

authors： Lambertenghi-Deliliers G,Benazzi E,Cortelezzi A,Polli EE

更新日期：1987-01-01 00:00:00

abstract：:Automated cytochemistry by the Hemalog D carries out leukocyte differential counts in a continuous flow mode on whole blood EDTA-collected samples, through the optical measurement of enzyme activity and cell size. This operative principle thus parallels the basis of the FAB classification of acute leukemias. Although ...

journal_title：Acta haematologica

authors： d'Onofrio G,Mango G

更新日期：1984-01-01 00:00:00

abstract：:Avascular necrosis (AVN) of the hip is a common cause of morbidity in sickle cell disease (SCD). Its prevalence increases with age and predisposing factors include coexistent alpha-thalassemia trait, frequent vaso-occlusive crisis and a high hematocrit (Hct). SCD is relatively mild among Kuwaiti patients because of th...

journal_title：Acta haematologica

authors： Adekile AD,Gupta R,Yacoub F,Sinan T,Al-Bloushi M,Haider MZ

更新日期：2001-01-01 00:00:00

abstract：:We report a patient with lung cancer who developed CD56-positive acute lymphoblastic leukemia. He was referred to our hospital for thrombocytopenia. Atypical cells were found in the blood and the bone marrow. These cells were immunophenotypically positive for CD3epsilon, CD56, and terminal deoxynucleotidyl transferase...

journal_title：Acta haematologica

authors： Matano S,Terahata S,Nakamura S,Kobayashi K,Sugimoto T

更新日期：2005-01-01 00:00:00

abstract：:Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a rare lymphoproliferative disorder characterized by diffuse lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, and polyclonal hypergammaglobulinemia. Morphologically, the involved lymph nodes demonstrate complete effacement of the normal arch...

journal_title：Acta haematologica

authors： Sallah S,Gagnon GA

更新日期：1998-01-01 00:00:00

abstract：:It was found that neutrophils in untreated uraemic patients as well as in subjects on regular dialysis treatment displayed higher activity of acid phosphatase, alkaline phosphatase and peroxidase. Spontaneous reduction of nitro blue tetrazolium (NBT) by granulocytes was also higher in both groups in comparison to cont...

journal_title：Acta haematologica

authors： Sutowicz W,Komorowska Z,Hanicki Z,Cichocki T,Smoleński O

更新日期：1979-01-01 00:00:00

abstract：:Herein, we describe a case of a female patient in whom B cell chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) were diagnosed simultaneously. She presented with anemia, thrombocytopenia and splenomegaly. Flow cytometry demonstrated two immunophenotypically distinct CD5-positive monoclonal B cell popul...

journal_title：Acta haematologica

authors： Kourelis TV,Kahl BS,Benn P,Delach JA,Bilgrami SF

更新日期：2011-01-01 00:00:00

abstract：:Malaria parasites growing inside human erythrocytes differ from mammalian cells in their mode of acquisition of bioavailable iron and in their susceptibility to the antiproliferative action of iron chelators. We have assessed here three major properties associated with these phenomena: (a) the stage-dependent nature o...

journal_title：Acta haematologica

authors： Cabantchik ZI,Glickstein H,Golenser J,Loyevsky M,Tsafack A

更新日期：1996-01-01 00:00:00

abstract：:Micromegakaryocytes (MMK) were defined morphologically by the cell area, nucleus form and cytoplasmic structure. Bone marrow smears of 7,156 patients were retrospectively analyzed. MMK were found most frequently and abundantly in acute non-lymphatic leukaemia, chronic myeloid leukaemia and pre-leukaemia. The presence ...

journal_title：Acta haematologica

authors： Wiesneth M,Pflieger H,Kubanek B,Heimpel H

更新日期：1980-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：:We describe a patient with recurrence of Hodgkin's disease and severe liver disease of unknown origin in whom autoimmune neutropenia developed. Because of possible seronegative viral hepatitis he was treated with high-dose intravenous immunoglobulin instead of steroids. He responded with a prompt but transitory increa...

journal_title：Acta haematologica

authors： Schoengen A,Fembacher PM,Schulz PC

更新日期：1995-01-01 00:00:00

abstract：:Acute myeloid leukemia (AML) is a stem cell malignancy that originates in the bone marrow and involves the peripheral blood. Extramedullary AML is rarer, but it is most commonly associated with the former French-American-British (FAB) subtypes M4 or M5 of AML. AML cells may also home to the central nervous system and ...

journal_title：Acta haematologica

authors： Patel SA,Bledsoe JR,Gordon J,Cerny J

更新日期：2020-08-19 00:00:00

abstract：:We evaluated the results of high-dose therapy (HDT) and autologous hematopoietic stem cell transplantation (ASCT) in patients with relapsed or primary refractory Hodgkin's disease (HD), using a previously reported prognostic model based on the presence of three poor prognostic factors at the start of salvage therapy/p...

journal_title：Acta haematologica

authors： Qazilbash MH,Devetten MP,Abraham J,Lynch JP,Beall CL,Auber M,Weisenborn R,Bunner P,Ericson SG

更新日期：2003-01-01 00:00:00

abstract：:We describe a B cell chronic lymphocytic leukemia/lymphoma (B-CLL) patient with an adrenocortical adenoma. He was treated initially with oral cyclophosphamide and prednisolone for 2 months, followed by low-dose prednisolone for an additional 2 years, which resulted in the prompt disappearance of CLL cells. After a per...

journal_title：Acta haematologica

authors： Adachi Y,Adachi M,Hinoda Y,Fukushima H,Takahashi T,Imai K

更新日期：1997-01-01 00:00:00

abstract：:A study of E-rosette ultrathin sections has been undertaken in an attempt to analyze changes induced during the T-lymphocyte-sheep red blood cell interaction on the rosetted lymphocyte surface architecture. The formation of nonimmune rosettes implies different types of attachment between lymphocytes and sheep red bloo...

journal_title：Acta haematologica

authors： Renau-Piqueras J,Cervera J

更新日期：1979-01-01 00:00:00

abstract：:While sickle cell disease (SCD) is generally mild in most Kuwaitis, because of their elevated fetal Hb levels, avascular necrosis of the femoral head (AVNFH) appears to be a common complication. It was recently documented in 26.7% of Kuwaiti children with SCD. There have, however, been no previous studies of adult pat...

journal_title：Acta haematologica

authors： Marouf R,Gupta R,Haider MZ,Al-Wazzan H,Adekile AD

更新日期：2003-01-01 00:00:00

abstract：:Factor VIII (FVIII) inhibitor antibodies are produced against functional epitopes of FVIII in about 30% of severe hemophilia A patients leading to inhibition of its procoagulant activity. The Bethesda assay, the most commonly used method to measure FVIII inhibitors, based on inhibition of coagulant activity of FVIII, ...

journal_title：Acta haematologica

authors： Towfighi F,Gharagozlou S,Sharifian RA,Kazemnejad A,Esmailzadeh K,Managhchi MR,Shokri F

更新日期：2005-01-01 00:00:00

abstract：:Serum soluble interleukin-6 receptor (sIL-6R) concentrations were measured in 50 patients with plasma cell dyscrasias using a commercially available immunoenzymatic assay kit. There were 40 patients with multiple myeloma (MM), 5 patients with monoclonal gammopathy of undetermined significance (MGUS), 3 patients with s...

journal_title：Acta haematologica

authors： Papadaki H,Kyriakou D,Foudoulakis A,Markidou F,Alexandrakis M,Eliopoulos GD

更新日期：1997-01-01 00:00:00

abstract：:Macrothrombocytopenia (MTP) is a group of rare disorders characterized by giant platelets, thrombocytopenia, and variable association with abnormal bleeding. Inherited MTP are frequently misdiagnosed as immune thrombocytopenia. Associated second-organ manifestation can help narrow down syndromic MTPs. We describe a ca...

journal_title：Acta haematologica

authors： Karki NR,Ajebo G,Savage N,Kutlar A

更新日期：2021-01-01 00:00:00

abstract：:A case of acute leukaemia with t(4;11) chromosomal abnormality in a 28-year-old woman is reported. At diagnosis, two blast cell populations were seen: 60% of the cells were small cells with lymphoid morphology, 40% were large cells with monocytic morphology. Cytochemical examination was consistent with acute myeloid l...

journal_title：Acta haematologica

authors： Campos L,Espinouse D,Felman P,Charrin C,Gentilhomme O,Germain D

更新日期：1986-01-01 00:00:00

abstract：:Acute megakaryoblastic leukemia is uncommon and comprises about 5% of acute nonlymphoid leukemias in the French-American-British classification. Cell lines from such leukemias are relatively rare with only about 8 reported in the literature. We established a cell line from a case of acute megakaryoblastic leukemia ari...

journal_title：Acta haematologica

authors： Skinnider LF,Pabello P,Zheng CY

更新日期：1997-01-01 00:00:00

abstract：:Recently, concerns have been raised regarding the potential impairment of neonatal platelet function and the potential risk of bleeding in neonates born to mothers treated with selective serotonin reuptake inhibitors (SSRI). Our aim was to test whether the platelet function of neonates born to SSRI-treated mothers was...

journal_title：Acta haematologica

authors： Maayan-Metzger A,Kuint J,Lubetsky A,Shenkman B,Mazkereth R,Kenet G

更新日期：2006-01-01 00:00:00

abstract：:During a screening for hemoglobinopathies, we found a carrier of the Sardinian δβ-thalassemia condition. The proband's hematology and hemoglobin (Hb) profile agreed with those of the other carriers previously identified during our diagnostic program except for the fetal Hb (HbF) composition, which consisted of both α2...

journal_title：Acta haematologica

authors： Trova S,Mereu P,Cocco E,Masala B,Manca L,Pirastru M

更新日期：2016-01-01 00:00:00

abstract：:Significant DNA polymorphisms have been reported in the beta-globin gene cluster of epsilon-G gamma-A gamma-psi beta-delta-beta-gene region, in normal (Hb AA) individuals and in patients with sickle cell anaemia (SCA). Investigations of the extent of the DNA polymorphisms in the beta A- and beta S-globin gene cluster ...

journal_title：Acta haematologica

authors： el-Hazmi MA,Bahakim HM,Warsy AS

更新日期：1992-01-01 00:00:00

abstract：:Gene therapy targeting hematopoietic cells has arrived at a new stage of potency. While the potential for curing inherited disorders of the immune system has been demonstrated in clinical trials, we were also confronted with the first serious adverse events related to random insertion of foreign DNA into cellular chro...

journal_title：Acta haematologica

authors： Baum C,von Kalle C

更新日期：2003-01-01 00:00:00

abstract：:Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients wich chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase of 'erythroblastic islands', i.e. erythrobl...

journal_title：Acta haematologica

authors： Sjögren U

更新日期：1976-01-01 00:00:00

abstract：:Fibroblast-like cells were grown from the bone marrow of acute lymphoblastic leukemia (ALL) patients before, during and off therapy. A diminished growth capacity was observed in cells from patients before and during therapy. In the three groups studied, differences were also observed in the effect of hydrocortisone on...

journal_title：Acta haematologica

authors： Bruzzone MS,Minguell JJ

更新日期：1985-01-01 00:00:00

abstract：:The dilution in the circulating blood of lymphocytes lablled in vitro with 3H-cytidine was examined after autotransfusion in 9 patients with Hodgkin's disease (HD) stage II A-IV B, 5 of whom were untreated; in 2 untreated patients with carcinoma, and in 1 treated patient with scleroderma. The blood transit time of exc...

journal_title：Acta haematologica

authors： Schick P,Trepel F,Eder M,Matzner M,Benedek S,Theml H,Kaboth W,Begemann H,Fliedner TM

更新日期：1975-01-01 00:00:00

abstract：:At our hospital, 47 out of 184 consecutive splenectomies performed over 7 recent years were carried out on patients afflicted with various hematologic diseases. The results of these 47 splenectomies were the subject of a careful retrospective analysis. The majority of the splenectomies (81%) were therapeutic. Cytopeni...

journal_title：Acta haematologica

authors： Dotevall A,Kutti J,Wadenvik H,Westin J,Angerås U,Darle N

更新日期：1987-01-01 00:00:00