Variations in morphological and immunological blast cell phenotype in a case of acute leukaemia with t(4;11) translocation.

abstract：:2 fatal cases of graft-versus-host disease (GvHD) occurred following blood product transfusions given to patients receiving standard chemotherapy for Hodgkin's disease. GvHD was established by HLA typing, clinical course, and compatible skin biopsy. 23 cases of GvHD following transfusion of blood products from normal ...

journal_title：Acta haematologica

authors： Burns LJ,Westberg MW,Burns CP,Klassen LW,Goeken NE,Ray TL,Macfarlane DE

更新日期：1984-01-01 00:00:00

abstract：:Thalidomide acts on the microenvironment of myelodysplastic syndromes (MDS) by influencing cytokine networks, and growing evidence supports thalidomide's usefulness in the management of haematological malignancies, such as MDS. The European Collaboration Group on Myelofibrosis with Myeloid Metaplasia reviewed patients...

journal_title：Acta haematologica

authors： Prentice HG,Sacchi S,Russell N

更新日期：2005-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：:A patient developed a drug rash and neutropenia while receiving tobramycin, ticarcillin and flucloxacillin intravenously for osteomyelitis. Incorporation of these antibiotics into in vitro cultures of bone marrow granulocyte macrophage precursors (CFU-C) showed no inhibition of the patient's marrow or normal marrow by...

journal_title：Acta haematologica

authors： Irvine AE,Morris TC,Kelly GJ,McCracken N

更新日期：1983-01-01 00:00:00

abstract：:Acute megakaryoblastic leukemia is uncommon and comprises about 5% of acute nonlymphoid leukemias in the French-American-British classification. Cell lines from such leukemias are relatively rare with only about 8 reported in the literature. We established a cell line from a case of acute megakaryoblastic leukemia ari...

journal_title：Acta haematologica

authors： Skinnider LF,Pabello P,Zheng CY

更新日期：1997-01-01 00:00:00

abstract：:Scanning electron microscopy has shown a typical cell surface morphology in hairy cell leukemia. Scanning immunoelectron microscope techniques, utilizing monoclonal antibodies and colloidal gold particles, have recently become available. Eight patients with hairy cell leukemia have been studied with a panel of monoclo...

journal_title：Acta haematologica

authors： Soligo D,Lambertenghi-Deliliers G,Nava MT,Polli N,Cattoretti G,Polli EE

更新日期：1985-01-01 00:00:00

abstract：:A hemophilia B patient, seropositive for HIV antibodies since 1984, came to us in March 1989 with a severe necrotizing lesion of the nose. It was an erythematous lesion and looked like rhinophyma. Microbiological examination of the skin biopsy showed the presence of Cryptococcus neoformans. At the time of the study, t...

journal_title：Acta haematologica

authors： Mares M,Sartori MT,Carretta M,Bertaggia A,Girolami A

更新日期：1990-01-01 00:00:00

abstract：:Thrombopoietin levels in thrombocytopenic mice assayed by 75Se-se-lenomethionine incorporation into blood platelets reached a maximum 12 h after the induction of an acute, immune thrombocytopenia; that was more than twice the value in control mice. The implications of this finding are discussed with reference to the k...

journal_title：Acta haematologica

authors： Nakeff A,Roozendaal KJ

更新日期：1975-01-01 00:00:00

abstract：:To evaluate the effect of granulocyte/colony-stimulating factor (G-CSF) on the onset of the adult respiratory distress syndrome (ARDS), we investigated whether the incidence of ARDS due to pulmonary infection differed between the G-CSF group which received chemotherapy with G-CSF and historical controls without G-CSF....

journal_title：Acta haematologica

authors： Takahashi Y,Kobayashi Y,Chikayama S,Ikeda M,Kondo M

更新日期：1999-01-01 00:00:00

abstract：:The transcription factors GATA-1 and GATA-2 play key roles in gene regulation during erythropoiesis. Gene ablation studies in mouse revealed that GATA-2 is crucial for the maintenance and proliferation of immature hematopoietic progenitors, whereas GATA-1 is essential for the survival of erythroid progenitors as well ...

journal_title：Acta haematologica

authors： Ohneda K,Yamamoto M

更新日期：2002-01-01 00:00:00

abstract：:A 26-year-old female with Ki-1-positive large-cell anaplastic lymphoma is reported. The neoplastic cells were phenotypically and genotypically of T cell origin. Initially, neoplastic cells invaded the skin and lymph nodes, and then invaded the sternal and vertebral bones, ribs and the iliopsoas muscle. Central nervous...

journal_title：Acta haematologica

authors： Tsukamoto N,Morita K,Maehara T,Mitsuhashi M,Karasawa M,Murakami H,Omine M,Naruse T,Yatabe H

更新日期：1992-01-01 00:00:00

abstract：:A case of multiple pyarthroses due to Staphylococcus aureus occurring in a severe classical hemophiliac is presented. Successful management depended on drainage of the infected joints and a prolonged course of antibiotics. Several criteria are suggested for recognition of hemophiliacs who might benefit from joint aspi...

journal_title：Acta haematologica

authors： Goldsmith JC,Silberstein PT,Fromm RE Jr,Walker DY

更新日期：1984-01-01 00:00:00

abstract：:Iron overload is a constant and the more important complication in thalassemia. Serum ferritin concentration accurately reflects body iron stores. A total of 245 thalassemic patients aged 12-55 years were examined, 71 having Hb H disease and 174 beta-thalassemia/Hb E disease. The patients received minimal or no blood ...

journal_title：Acta haematologica

authors： Pootrakul P,Vongsmasa V,La-ongpanich P,Wasi P

更新日期：1981-01-01 00:00:00

abstract：:We have retrospectively analyzed a series of 19 patients with hepatitis C virus (HCV) infection and chronic thrombocytopenia not attributable to hypersplenism or to other causes. Antiplatelet antibodies were present in 81% of cases. Response to prednisone was observed in 6 of 7 patients and 1 of 3 patients responded t...

journal_title：Acta haematologica

authors： Hernández F,Blanquer A,Linares M,López A,Tarín F,Cerveró A

更新日期：1998-01-01 00:00:00

abstract：:Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neopla...

journal_title：Acta haematologica

authors： Ringel F,Kaeda J,Schwarz M,Oberender C,Grille P,Dörken B,Marque F,Manley PW,Radimerski T,le Coutre P

更新日期：2014-01-01 00:00:00

abstract：:Bone marrow samples of 28 individuals with clinically benign and of 41 patients with malignant monoclonal gammopathy were analyzed for the total number of lymphoplasmocellular elements containing cytoplasmic immunoglobulins and for the monoclonal fraction of these cells. Monoclonal immunoglobulin components were deter...

journal_title：Acta haematologica

authors： Morell A,Maurer W,Skvaril F,Barandun S

更新日期：1978-01-01 00:00:00

abstract：:To characterize intracellular signaling in peripheral blood (PB) cells of acute myeloid leukemia (AML) patients undergoing pretransplant conditioning with CXCR4 inhibitor plerixafor, granulocyte colony-stimulating factor (G-CSF), and busulfan plus fludarabine (Bu+Flu) chemotherapy, we profiled 153 proteins in 33 funct...

journal_title：Acta haematologica

authors： Zeng Z,Liu W,Benton CB,Konoplev S,Lu H,Wang RY,Chen J,Shpall E,Baggerly KA,Champlin R,Konopleva M

更新日期：2019-01-01 00:00:00

abstract：:We describe a B cell chronic lymphocytic leukemia/lymphoma (B-CLL) patient with an adrenocortical adenoma. He was treated initially with oral cyclophosphamide and prednisolone for 2 months, followed by low-dose prednisolone for an additional 2 years, which resulted in the prompt disappearance of CLL cells. After a per...

journal_title：Acta haematologica

authors： Adachi Y,Adachi M,Hinoda Y,Fukushima H,Takahashi T,Imai K

更新日期：1997-01-01 00:00:00

abstract：:Monocytoid B cell lymphoma (MBCL) is an immunologically and morphologically well-defined low-grade lymphoma with a predilection for lymph nodes of the parotid region. We describe an association of MBCL with anti-myelin-associated glycoprotein (MAG) polyneuropathy in a 53-year-old male. The diagnosis of stage IV MBCL w...

journal_title：Acta haematologica

authors： Donfrid M,Apostolski S,Suvajdzić N,Janković G,Cemerikić-Martinović V,Atkinson HD,Colovic M

更新日期：2001-01-01 00:00:00

abstract：:We present a case with the clinical and pathological impression of Ph1-positive chronic myelogenous leukemia in extramedullary blast crisis involving lymph nodes as demonstrated by morphological and cytogenetic studies. The hyperploid cell lines that were present in the lymph node were not present in the bone marrow. ...

journal_title：Acta haematologica

authors： Velasquez ET,Verma RS,Krishnamurthy M,Dosik H

更新日期：1985-01-01 00:00:00

abstract：:It has been found possible to test ferritin concentrations in the reticulum and hemopoietic cells from human bone marrow by an immunoradiometric assay. Ferritin concentration in healthy test persons amounts to 0.92 +/- 0.38 ng/microgram protein in the reticulum and 0.084 +/- 0.031 ng/microgram protein in hemopoietic c...

journal_title：Acta haematologica

authors： Oertel J,Stephan M,Kastner M

更新日期：1982-01-01 00:00:00

abstract：:The goal of the study was to investigate changes in expression of selected growth factors tentatively involved in regeneration of haematopoietic tissues (bone marrow and spleen) following cyclophosphamide (CY) damage in the mouse. The bone marrow (BM) and spleen were examined separately, since the regenerating pattern...

journal_title：Acta haematologica

authors： Psenák O,Sefc L,Sýkora V,Chang KT,Necas E

更新日期：2003-01-01 00:00:00

abstract：:In the last 18 years, we have observed 24 cases of hypoparathyroidism (HPT) in beta-thalassemia major. At present, 4.5% of patients followed regularly in our department have this complication. HPT is thought to be mainly the consequence of iron deposition in the parathyroid glands. The age of our patients when HPT was...

journal_title：Acta haematologica

authors： De Sanctis V,Vullo C,Bagni B,Chiccoli L

更新日期：1992-01-01 00:00:00

abstract：:Serum IgG, IgM and IgA were determined in 25 patients with homozygous beta thalassemia and 7 with the trait. The levels were increased in homozygous patients and increased further after splenectomy. Serum opsonic activity against Salmonella typhi and staphylococci was impaired in homozygous patients. Splenectomy cause...

journal_title：Acta haematologica

authors： Khalifa AS,Fattah SA,Maged Z,Sabry F,Mohamed HA

更新日期：1983-01-01 00:00:00

abstract：:A case of lymphoma presenting with features shared by hairy cell leukemia (HCL) and its variant, intermediate lymphocytic lymphoma (ILL) and monocytoid B-cell lymphoma (MBCL) is described. Clinical presentation and the morphological findings observed in peripheral blood and in bone marrow biopsy suggested an HCL; howe...

journal_title：Acta haematologica

authors： Adami F,Chilosi M,Lestani M,Scarpa A,Zambello R,Pomponi F,Semenzato G,Menestrina F

更新日期：1993-01-01 00:00:00

abstract：:Granulocytic sarcoma of the small intestine preceding or as the presenting feature of acute myelogenous leukemia with chromosome 16 abnormalities has been observed in at least 4 patients. We report the case of a patient initially diagnosed with eosinophilic gastroenteritis, responding to corticosteroid treatment for 2...

journal_title：Acta haematologica

authors： Julia A,Nomdedeu JF

更新日期：2004-01-01 00:00:00

abstract：:Fourteen patients with hematologic neoplasia (11 acute myeloid leukemias, 2 non-Hodgkin's lymphomas and 1 blast crisis of chronic myeloid leukemia) who underwent high-dose cytosine arabinoside (HIDARAC) therapy with or without sequential asparaginase (ASNase) were investigated in order to evaluate liver toxicity and a...

journal_title：Acta haematologica

authors： Marra R,Pagano L,De Stefano V,Leone G,Bizzi B

更新日期：1986-01-01 00:00:00

abstract：:15 patients with aplastic anemia were prospectively followed after having measurements of myeloid progenitor cells in bone marrow and blood. Treatment included androgens, low or high dose steroids and standardized supportive care. The median length of survival was 5.8 months. When patients were grouped according to th...

journal_title：Acta haematologica

authors： Hinterberger W,Geissler K,Fischer M,Lechner K,Kabrna E

更新日期：1985-01-01 00:00:00

abstract：:Amylase-producing tumors are mainly adenocarcinomas and, in rare instances, multiple myelomas. We describe here a first case of amylase-producing Bence Jones type myeloma with pancreatitis-like symptoms and the second in a Caucasian patient. The finding of salivary-type hyperamylasemia in a 72-year-old female with a p...

journal_title：Acta haematologica

authors： Lopez J,Ulibarrena C,Gonzalez-Porque P,Navas G,Roldan E,Cancelas JA,Perez-Oteyza J,Burgaleta C,García-Laraña J,Sastre JL

更新日期：1993-01-01 00:00:00

abstract：:A patient with common acute lymphoblastic leukaemia (ALL), hypereosinophilic syndrome and t(5;14) (q31.1;q32.3) translocation is described. Even with intensive treatment only short periods of complete remission were achieved. Recurrence of the leukaemia was always accompanied by the appearance of eosinophilic granuloc...

journal_title：Acta haematologica

authors： Baumgarten E,Wegner RD,Fengler R,Ludwig WD,Schulte-Overberg U,Domeyer C,Schüürmann J,Henze G

更新日期：1989-01-01 00:00:00