Immunoglobulin therapy for autoimmune neutropenia in Hodgkin's disease.

abstract：:The detection and enumeration of sideroblasts depend critically on the method used for iron staining of bone marrow smears. Several methods proposed for semiquantitative evaluation of bone marrow hemosiderin (iron stores) were compared with respect to their suitability for detection of normal and abnormal sideroblasts...

journal_title：Acta haematologica

authors： Baumgartner-Stäubli R,Beck EA

更新日期：1977-01-01 00:00:00

abstract：:To characterize intracellular signaling in peripheral blood (PB) cells of acute myeloid leukemia (AML) patients undergoing pretransplant conditioning with CXCR4 inhibitor plerixafor, granulocyte colony-stimulating factor (G-CSF), and busulfan plus fludarabine (Bu+Flu) chemotherapy, we profiled 153 proteins in 33 funct...

journal_title：Acta haematologica

authors： Zeng Z,Liu W,Benton CB,Konoplev S,Lu H,Wang RY,Chen J,Shpall E,Baggerly KA,Champlin R,Konopleva M

更新日期：2019-01-01 00:00:00

abstract：:Although multiple myeloma (MM) remains an incurable disease, its treatment has improved over the past decade. This improvement has been at least in part due to the introduction of novel antimyeloma agents with new mechanisms of action, including those that target both myeloma cells and the tumor microenvironment, with...

journal_title：Acta haematologica

authors： Cibeira MT,Mercadal S,Arenillas L,Muntañola A,Salamero O,Bladé J

更新日期：2006-01-01 00:00:00

abstract：:Leukemic cells of a patient with acute T-lymphoblastic leukemia (T-ALL) exhibiting the uncommon clinical feature of hypogammaglobulinemia were examined in terms of surface markers and immunologic functions. Employing various monoclonal reagents reacting with surface antigens present on T cells and additional conventio...

journal_title：Acta haematologica

authors： Herrmann F,Sieber G,Komischke B,Oestreich R,Rühl H

更新日期：1984-01-01 00:00:00

abstract：:Alpha-thalassemia is very common in the Kuwaiti population, but its influence on anemia of pregnancy has not been previously investigated. We have screened a group of 59 anemic (Hb < 11 g/dl) pregnant women for the alpha-thal-2 (-alpha-3.7 kb) deletion which is the commonest alpha-thal allele in this community, using ...

journal_title：Acta haematologica

authors： Diejomaoh FM,Haider MZ,Dalal H,Abdulaziz A,D'Souza TM,Adekile AD

更新日期：2000-01-01 00:00:00

abstract：:Analysis of donor chimerism has become a routine method for the documentation of engraftment after allogeneic hematopoietic stem cell transplantation (HSCT). In recent years several groups have also focused on the application of this technique for the detection of relapsing disease after allogeneic HSCT. This review a...

journal_title：Acta haematologica

authors： Thiede C,Bornhäuser M,Ehninger G

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:It is a common belief among women that iron compounds have unpleasant gastrointestinal side effects. OBJECTIVE:To assess the gastrointestinal side effects of iron prophylaxis in pregnancy. METHODS:A randomized, double-blind study comprising 404 healthy pregnant women allocated to four groups taking ferrous...

journal_title：Acta haematologica

authors： Milman N,Byg KE,Bergholt T,Eriksen L

更新日期：2006-01-01 00:00:00

abstract：:The severe endothelial dysfunction in children with acute lymphoblastic leukemia (ALL) can result from the disease itself, from treatment, or from other conditions (e.g. sepsis). The aim of this study was to determine the levels of markers of endothelial activation in children with ALL and to assess their potential pr...

journal_title：Acta haematologica

authors： Hatzipantelis ES,Athanassiou-Metaxa M,Gombakis N,Tzimouli V,Taparkou A,Sidi-Fragandrea V,Garipidou V,Papageorgiou T,Kleta D,Koliouskas DE,Athanasiadou-Piperopoulou F

更新日期：2011-01-01 00:00:00

abstract：:Non-transfusion-dependent thalassemia (NTDT) is associated with various forms of thalassemia and genetic modifiers. We report the molecular basis of NTDT in hemoglobin (Hb) E-β-thalassemia disease. This study was done in 73 adult patients encountered at the prenatal diagnosis center of Khon Kaen University, Northeast ...

journal_title：Acta haematologica

authors： Yamsri S,Pakdee N,Fucharoen G,Sanchaisuriya K,Fucharoen S

更新日期：2016-01-01 00:00:00

abstract：:Hypercalcemia in malignancies is a frequent complication, mostly affecting patients with solid tumors or multiple myeloma. Calcium elevation is induced by direct bone infiltration of a tumor mass or through calcium liberation from the skeleton by a humoral mediator. The latter mechanism is referred to as humoral hyper...

journal_title：Acta haematologica

authors： Kampfenkel T,Baraniskin A,Teschendorf C,Schmiegel W,Massenkeil G

更新日期：2010-01-01 00:00:00

abstract：:A case of angioimmunoblastic lymphadenopathy (AILD) with important autoimmune symptoms disappearing under Levamisole therapy is reported. Since Levamisole is thought to have no direct effect on B cells, it is supposed that in AILD it regulates B lymphocyte activity via the restoration of impaired T cell functions. ...

journal_title：Acta haematologica

authors： Andrieu JM,Youinou P,Herzog C

更新日期：1979-01-01 00:00:00

abstract：:Extensive bone marrow necrosis and symptomatic hypercalcemia have been described independently as rare complications of chronic myeloid leukemia. Here we report a 66-year-old man who developed B cell blastic transformation 10 years after diagnosis of CML in the chronic phase. Extensive bone marrow necrosis and symptom...

journal_title：Acta haematologica

authors： Noguchi M,Oshimi K

更新日期：2007-01-01 00:00:00

abstract：:Platelet-derived growth factor (PDGF) is thought to take part in the genesis of bone marrow fibrosis that can be found in patients with myeloproliferative diseases. We evaluated platelet mitogenic activity as the difference between serum and plasma activity in 8 patients with myeloproliferative disease. We observed a ...

journal_title：Acta haematologica

authors： Caenazzo A,Pietrogrande F,Polato G,Piva E,Masiero M,Sgarabotto D,Girolami A

更新日期：1989-01-01 00:00:00

abstract：:Gene therapy targeting hematopoietic cells has arrived at a new stage of potency. While the potential for curing inherited disorders of the immune system has been demonstrated in clinical trials, we were also confronted with the first serious adverse events related to random insertion of foreign DNA into cellular chro...

journal_title：Acta haematologica

authors： Baum C,von Kalle C

更新日期：2003-01-01 00:00:00

abstract：:Fetal liver transplantation was attempted in 7 patients with aplastic anemia. 4 of these patients showed a partial response as evidenced by decrease in blood transfusion requirements and increase in the peripheral blood counts and hematopoietic cells in the bone marrow. Bone marrow culture studies revealed evidence of...

journal_title：Acta haematologica

authors： Kansal V,Sood SK,Batra AK,Adhar G,Malviya AK,Kucheria K,Balakrishnan K

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Umbilical cord blood (UCB) contains haematopoietic stem cells and can be used as an alternative to bone marrow transplantation in certain cases. Engraftment was dependent upon the haematopoietic progenitor cell content of the cord blood units. This study was designed to investigate the influen...

journal_title：Acta haematologica

authors： Solves P,Perales A,Moraga R,Saucedo E,Soler MA,Monleon J

更新日期：2005-01-01 00:00:00

abstract：:We present the case of a woman undergoing treatment with acenocoumarol for deep vein thrombosis, who maintained an international normalized ratio (INR) of between 2.5 and 4 for 2 months. Seven days after the introduction of amoxycillin (500 mg/8 h) for a probable respiratory infection, the patient developed spontaneou...

journal_title：Acta haematologica

authors： Soto J,Sacristan JA,Alsar MJ,Fernandez-Viadero C,Verduga R

更新日期：1993-01-01 00:00:00

abstract：:The detection of cellular antigens in bone marrow sections depends on the method of embedding, the nature of antigen and antibody, antigen retrieval techniques and the sensitivity of the immunohistochemical method. This study evaluated a fluorescyl-tyramide-enhanced immunostaining method on methyl-methacrylate-embedde...

journal_title：Acta haematologica

authors： Gaiser T,Bernhards J

更新日期：2007-01-01 00:00:00

abstract：:Iron overload is a constant and the more important complication in thalassemia. Serum ferritin concentration accurately reflects body iron stores. A total of 245 thalassemic patients aged 12-55 years were examined, 71 having Hb H disease and 174 beta-thalassemia/Hb E disease. The patients received minimal or no blood ...

journal_title：Acta haematologica

authors： Pootrakul P,Vongsmasa V,La-ongpanich P,Wasi P

更新日期：1981-01-01 00:00:00

abstract：:The dilution in the circulating blood of lymphocytes lablled in vitro with 3H-cytidine was examined after autotransfusion in 9 patients with Hodgkin's disease (HD) stage II A-IV B, 5 of whom were untreated; in 2 untreated patients with carcinoma, and in 1 treated patient with scleroderma. The blood transit time of exc...

journal_title：Acta haematologica

authors： Schick P,Trepel F,Eder M,Matzner M,Benedek S,Theml H,Kaboth W,Begemann H,Fliedner TM

更新日期：1975-01-01 00:00:00

abstract：:A 67-year-old woman with agnogenic myeloid metaplasia, who underwent splenectomy 1 year after the diagnosis, experienced spontaneous hematologic remission 6 years after splenectomy. Ten months before her anemia improved, peripheral leukocytes no longer showed a shift to the left and peripheral erythroblasts had disapp...

journal_title：Acta haematologica

authors： Shimizu K,Hotta T

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The relation with SNF5 mutation and chromosome 22 abnormalities is not clear in hematological neoplasms. METHODS:To elucidate the relevance of the SNF5 gene on 22q11.2, karyotypes were reviewed in 283 hematological neoplasms. Loss of heterozygosity (LOH) on 22q was analyzed in 21 plasma cell myelomas withou...

journal_title：Acta haematologica

authors： Mori N,Inoue K,Okada M,Motoji T

更新日期：2011-01-01 00:00:00

abstract：:Red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-chromosomal-linked abnormality often associated with hemolytic anemia. The G6PD variants obtained from 2 unrelated males, one associated with enzyme deficiency and history of hemolytic jaundice, and the other associated with enzyme deficiency but no ...

journal_title：Acta haematologica

authors： Sáenz GF,Chaves M,Berrantes A,Elizondo J,Montero AG,Yoshida A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND/AIMS:The study was undertaken to understand the characteristic of plasma cell leukemia (PCL) in China. METHODS:We reviewed and compared medical data of 22 primary PCL, 9 secondary PCL and 461 multiple myeloma (MM) diagnosed at our institute from January 2000 to January 2008. RESULTS:The median onset ages o...

journal_title：Acta haematologica

authors： Peijing Q,Yan X,Yafei W,Dehui Z,Zengjun L,Junyuan Q,Yaozhong Z,Lugui Q

更新日期：2009-01-01 00:00:00

abstract：:The short-term effect of a domestically produced equine antithymocyte globulin (ATG) was analyzed in 6 patients with acquired severe aplastic anemia (AA). All patients received 5 doses of ATG every other day in a 60-min intravenous infusion. Five peripheral blood immunoregulatory mononuclear cell (MNC) subsets, define...

journal_title：Acta haematologica

authors： López-Karpovitch X,Zarzosa ME,Cárdenas MR,Piedras J

更新日期：1989-01-01 00:00:00

abstract：:Pyrimidine 5'-nucleotidase (P5'N) partial deficiency has been described in several hematological disorders and also in the beta-thalassemic trait. To check if the P5'N deficiency in thalassemia was acquired we used thalassemic red cells (from either homo- or heterozygous subjects), whose P5'N activity was lower than i...

journal_title：Acta haematologica

authors： David O,Vota MG,Piga A,Ramenghi U,Bosia A,Pescarmona GP

更新日期：1989-01-01 00:00:00

abstract：:Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, i...

journal_title：Acta haematologica

authors： Guastafierro S,Tedeschi A,Criscuolo C,Celentano M,Cobellis L,Rossiello R,Falcone U

更新日期：2012-01-01 00:00:00

abstract：:A family with hereditary ovalocytosis (HO) is described. The probands, 2 brothers, had splenic rupture after modest trauma as preenting symptoms. 7 members of the family had HO. The sister of the pobands had a moderately enlarged spleen. The other members proved normal on routine clinical examination. ...

journal_title：Acta haematologica

authors： Kjellman B,Larsson C,Tibblin E

更新日期：1980-01-01 00:00:00

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00

abstract：:Recently, a factor was discovered in the serum of hepatectomized animals which was capable of augmenting the hepatic erythropoietin response to hypoxia when injected into normal rats. This substance was localized in the liver via an in situ perfusion technique and was termed the hepatic erythropoietic factor (HEF). Pa...

journal_title：Acta haematologica

authors： Naughton BA,Liu P,Naughton GK,Gordon AS

更新日期：1983-01-01 00:00:00