Medication Adherence to Tyrosine Kinase Inhibitors: 2-Year Analysis of Medication Adherence to Imatinib Treatment for Chronic Myeloid Leukemia and Correlation with the Depth of Molecular Response.

abstract：:Richter syndrome (RS) describes the development of high-grade non-Hodgkin's lymphoma (NHL) from low-grade NHL. RS isolated to the brain is very rare and has a poor prognosis. We describe the cases of high-grade large B-cell diffuse NHL in a 56-year-old male with chronic lymphocytic leukemia and in a 71-year-old female...

journal_title：Acta haematologica

authors： Stuplich M,Mayer K,Kim Y,Thanendrarajan S,Simon M,Schäfer N,Glas M,Schmidt-Wolf IG,Herrlinger U

更新日期：2012-01-01 00:00:00

abstract：:Transient regression in the lymphocyte count of a patient with B-cell chronic lymphocytic leukemia (B-CLL) after viral infection is reported. A similar event occurred under natural interferon-alpha (IFN-alpha) treatment. It was confirmed that the event was not caused by a direct cytotoxic effect of IFN-alpha by analyz...

journal_title：Acta haematologica

authors： Shirono K,Ikebe M,Inada T,Tsuda H

更新日期：1995-01-01 00:00:00

abstract：:Fetal liver transplantation was attempted in 7 patients with aplastic anemia. 4 of these patients showed a partial response as evidenced by decrease in blood transfusion requirements and increase in the peripheral blood counts and hematopoietic cells in the bone marrow. Bone marrow culture studies revealed evidence of...

journal_title：Acta haematologica

authors： Kansal V,Sood SK,Batra AK,Adhar G,Malviya AK,Kucheria K,Balakrishnan K

更新日期：1979-01-01 00:00:00

abstract：:Platelet to leukocyte adhesion phenomena (PLAP) and the phagocytosis of platelets by neutrophils from the EDTA anticoagulated blood samples are described. PLAP was transferable to a normal blood specimen by patient's plasma or serum with or without complement. Further studies revealed in vitro evidence of hereditary p...

journal_title：Acta haematologica

authors： Yoo D,Weems H,Lessin LS

更新日期：1982-01-01 00:00:00

abstract：:Primary plasma cell leukemia (PCL) is a rare form of plasma cell neoplasm with a poor prognosis. Conventional melphalan-based treatments have been most disappointing. We report the case of a 62-year-old man with a primary form of PCL treated with VAD combination achieving an objective response, and who received high-d...

journal_title：Acta haematologica

authors： Panizo C,Rifón J,Rodríguez-Wilhelmi P,Cuesta B,Rocha E

更新日期：1999-01-01 00:00:00

abstract：:The most common single genetic disorder and a major public health issue in Greece and other Mediterranean countries is beta-thalassemia. Current therapeutic approaches for homozygous beta-thalassemia entail blood transfusions and iron chelation therapy with deferoxamine or deferiprone for preventing tissue hemosideros...

journal_title：Acta haematologica

authors： Chaidos A,Makis A,Hatzimichael E,Tsiara S,Gouva M,Tzouvara E,Bourantas KL

更新日期：2004-01-01 00:00:00

abstract：:In the chronic wound, the normal cascade of inflammation, granulation and reconstruction phases of healing is interrupted. Cytokines are now known to orchestrate different biochemical mediators resulting in the restoration of the healing phases. Growth factors may play a significant role in stimulating wound repair by...

journal_title：Acta haematologica

authors： Nath C,Gulati SC

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVES:Reticulated platelets circulating in the blood reflect megakaryopoietic activity and platelet turnover and can be automatically and low-invasively measured as the immature platelet fraction (IPF) using a Sysmex XN hematocytometer. The present study retrospectively investigated whether or not the IPF can pred...

journal_title：Acta haematologica

authors： Takami A,Mizuno S,Nakamura A,Kanasugi J,Yamamoto H,Vu Quang L,Nakagami Y,Nakano Y,Yamada S,Matsumura S,Takasugi S,Uchino K,Horio T,Murakami S,Oohigashi Y,Nakayama T,Tani H,Enomoto M,Hanamura I

更新日期：2020-09-17 00:00:00

abstract：:Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support hematopoietic differentiation of allogeneic cord blood cells in ...

journal_title：Acta haematologica

authors： Thalmeier K,Meissner P,Moosmann S,Sagebiel S,Wiest I,Huss R

更新日期：2001-01-01 00:00:00

abstract：:We describe a B cell chronic lymphocytic leukemia/lymphoma (B-CLL) patient with an adrenocortical adenoma. He was treated initially with oral cyclophosphamide and prednisolone for 2 months, followed by low-dose prednisolone for an additional 2 years, which resulted in the prompt disappearance of CLL cells. After a per...

journal_title：Acta haematologica

authors： Adachi Y,Adachi M,Hinoda Y,Fukushima H,Takahashi T,Imai K

更新日期：1997-01-01 00:00:00

abstract：:In 34 patients with chronic lymphatic leukaemia (CLL) the lymphocytes have been separated and sized using a C1000 Channelyzer. The modal volume and the volume range of the populations have been obtained and related to clinical stage and mouse red blood cell (MRBC) rosetting capacity. Over 1 year's observation with sev...

journal_title：Acta haematologica

authors： Wastell HJ,Proctor SJ

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND AND OBJECTIVES:Umbilical cord blood (UCB) contains haematopoietic stem cells and can be used as an alternative to bone marrow transplantation in certain cases. Engraftment was dependent upon the haematopoietic progenitor cell content of the cord blood units. This study was designed to investigate the influen...

journal_title：Acta haematologica

authors： Solves P,Perales A,Moraga R,Saucedo E,Soler MA,Monleon J

更新日期：2005-01-01 00:00:00

abstract：:Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients wich chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase of 'erythroblastic islands', i.e. erythrobl...

journal_title：Acta haematologica

authors： Sjögren U

更新日期：1976-01-01 00:00:00

abstract：:The first thrombocytopenia cases related to the human immunodeficiency virus (HIV) were described even before its isolation in 1983. Subsequently, multiple mechanisms have been proposed to elucidate the etiology of thrombocytopenia. In addition to other types of cytopenia affecting patients with HIV, thrombocytopenia ...

journal_title：Acta haematologica

authors： Passos AM,Treitinger A,Spada C

更新日期：2010-01-01 00:00:00

abstract：:A 67-year-old woman with agnogenic myeloid metaplasia, who underwent splenectomy 1 year after the diagnosis, experienced spontaneous hematologic remission 6 years after splenectomy. Ten months before her anemia improved, peripheral leukocytes no longer showed a shift to the left and peripheral erythroblasts had disapp...

journal_title：Acta haematologica

authors： Shimizu K,Hotta T

更新日期：1990-01-01 00:00:00

abstract：:Micromegakaryocytes (MMK) were defined morphologically by the cell area, nucleus form and cytoplasmic structure. Bone marrow smears of 7,156 patients were retrospectively analyzed. MMK were found most frequently and abundantly in acute non-lymphatic leukaemia, chronic myeloid leukaemia and pre-leukaemia. The presence ...

journal_title：Acta haematologica

authors： Wiesneth M,Pflieger H,Kubanek B,Heimpel H

更新日期：1980-01-01 00:00:00

abstract：:Immunoglobulin light chain amyloidosis (AL amyloidosis) is a rare, life-threatening disease characterized by the deposition of misfolded proteins in vital organs such as the heart, the lungs, the kidneys, the peripheral nervous system, and the gastrointestinal tract. This causes a direct toxic effect, eventually leadi...

journal_title：Acta haematologica

authors： Van Doren L,Lentzsch S

更新日期：2020-01-01 00:00:00

abstract：:We describe an unusual case of invasive pulmonary aspergillosis (IPA) complicated by subclavian artery occlusion in a 32-year-old man with severe aplastic anemia, who underwent allogeneic stem cell transplantation. He was severely neutropenic after the conditioning for transplantation, but he had no history of fungal ...

journal_title：Acta haematologica

authors： Hashino S,Imamura M,Tanaka J,Mori A,Noto S,Kobayashi S,Kasai M,Asaka M

更新日期：1997-01-01 00:00:00

abstract：:We evaluated the results of high-dose therapy (HDT) and autologous hematopoietic stem cell transplantation (ASCT) in patients with relapsed or primary refractory Hodgkin's disease (HD), using a previously reported prognostic model based on the presence of three poor prognostic factors at the start of salvage therapy/p...

journal_title：Acta haematologica

authors： Qazilbash MH,Devetten MP,Abraham J,Lynch JP,Beall CL,Auber M,Weisenborn R,Bunner P,Ericson SG

更新日期：2003-01-01 00:00:00

abstract：:Essential thrombocythemia (ET), one of the chronic myeloproliferative disorders, is a clonal disorder of multipotent stem cells. Although most patients with ET have a prolonged benign course, a minority of patients may develop a blastic crisis similar to chronic myelogenous leukemia (CML). A case of ET terminating in ...

journal_title：Acta haematologica

authors： Shibata K,Shimamoto Y,Suga K,Sano M,Matsuzaki M,Yamaguchi M

更新日期：1994-01-01 00:00:00

abstract：:A family with hereditary ovalocytosis (HO) is described. The probands, 2 brothers, had splenic rupture after modest trauma as preenting symptoms. 7 members of the family had HO. The sister of the pobands had a moderately enlarged spleen. The other members proved normal on routine clinical examination. ...

journal_title：Acta haematologica

authors： Kjellman B,Larsson C,Tibblin E

更新日期：1980-01-01 00:00:00

abstract：:A case of steroid-resistant acquired pure red-cell aplasia associated with a relative and absolute increase of TG cells is described. Removal of T cells enhanced erythroid colony and burst formation in vitro, and it is suggested that TG cells may be implicated in the pathogenesis of this case of acquired pure red-cell...

journal_title：Acta haematologica

authors： Linch DC,Cawley JC,MacDonald SM,Masters G,Roberts BE,Antonis AH,Waters AK,Sieff C,Lydyard PM

更新日期：1981-01-01 00:00:00

abstract：:Cancer patients not undergoing treatment and without a history of venous thrombosis do not, as a general rule, require prophylaxis. However, venous thromboembolism is of sufficient magnitude in patients undergoing treatment for cancer for thromboprophylaxis to be routinely employed. The mainstay of primary prevention ...

journal_title：Acta haematologica

authors： Thodiyil PA,Walsh DC,Kakkar AK

更新日期：2001-01-01 00:00:00

abstract：:We investigated double (specific and nonspecific) esterase (DE) staining in marrow cells of 237 patients with the myelodysplastic syndromes (MDS). Additional abnormalities of neutrophilic granules were examined cytochemically and immunocytochemically for myeloperoxidase activity and antigen elastase, lactoferrin and C...

journal_title：Acta haematologica

authors： Elghetany MT,Peterson B,MacCallum J,Nelson DA,Varney JF,Sullivan AK,Silverman LR,Schiffer CA,Davey FR,Bloomfield CD

更新日期：1998-01-01 00:00:00

abstract：:Natural killer (NK) cell activity against K562 cell targets and the distribution of T cell subpopulations were investigated in the peripheral blood of 25 patients affected by beta thalassemia major, 18 clinically healthy heterozygotes, and 25 age-matched normal subjects. It was found that thalassemia major patients di...

journal_title：Acta haematologica

authors： Neri A,Brugiatelli M,Iacopino P,Callea V,Ronco F

更新日期：1984-01-01 00:00:00

abstract：:A 16-year-old Japanese woman with acute myelogenous leukemia (AML) and t(6;9) received peripheral blood stem cell transplantation (PBSCT). Although chromosomal studies just prior to and following PBSCT showed a normal karyotype, reverse transcription-polymerase chain reaction (RT-PCR) detected the mRNA derived from th...

journal_title：Acta haematologica

authors： Nakano H,Shimamoto Y,Suga K,Kobayashi M

更新日期：1995-01-01 00:00:00

abstract：:The adaptation of cell physiological parameters of erythrocytes of the newborn to erythrocytes in later life was studied by cell separation in an isopycnic dextran density gradient. The cell characteristics during the first trimester of life were followed by repeated determinations. The mean cellular haemoglobin conce...

journal_title：Acta haematologica

authors： Grauel EL,Müller S,Gross J,Syllm-Rapoport I

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:To review the diagnostic significance, safety and possible risk factors of splenectomy in fever of unknown origin (FUO) with splenomegaly. METHODS:The records of 54 patients with FUO and splenomegaly who underwent splenectomy in our hospital in the past 20 years were reviewed retrospectively. Pathologic find...

journal_title：Acta haematologica

authors： Han B,Yang Z,Yang T,Gao W,Sang X,Zhao Y,Shen T

更新日期：2008-01-01 00:00:00

abstract：:We have retrospectively analyzed a series of 19 patients with hepatitis C virus (HCV) infection and chronic thrombocytopenia not attributable to hypersplenism or to other causes. Antiplatelet antibodies were present in 81% of cases. Response to prednisone was observed in 6 of 7 patients and 1 of 3 patients responded t...

journal_title：Acta haematologica

authors： Hernández F,Blanquer A,Linares M,López A,Tarín F,Cerveró A

更新日期：1998-01-01 00:00:00

abstract：:Drug-induced immune hemolytic anemia is a rare but underdiagnosed and potentially fatal condition. We report a case of severe hemolytic anemia induced by cefoxitin in a 45-year-old woman admitted with menometrorrhagia. Hemoglobin levels reached a nadir of 4.7 g/dl approximately 72 h after cefoxitin initiation, and hem...

journal_title：Acta haematologica

authors： Leaf DE,Langer NB,Markowski M,Garratty G,Diuguid DL

更新日期：2010-01-01 00:00:00