Serological and biochemical analyses of M components in patients with transitional cell carcinoma of the urinary bladder.

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00

abstract：:We present a case with the clinical and pathological impression of Ph1-positive chronic myelogenous leukemia in extramedullary blast crisis involving lymph nodes as demonstrated by morphological and cytogenetic studies. The hyperploid cell lines that were present in the lymph node were not present in the bone marrow. ...

journal_title：Acta haematologica

authors： Velasquez ET,Verma RS,Krishnamurthy M,Dosik H

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The treatment of relapsed/refractory (R/R) peripheral T cell lymphoma (PTCL) is limited to a few agents. Romidepsin, a histone deacetylase inhibitor, was approved for PTCL treatment as a single agent in the R/R setting, yet with partial efficacy. Several attempts to combine romidepsin with other chemotherapy...

journal_title：Acta haematologica

authors： Nachmias B,Shaulov A,Lavie D,Goldschmidt N,Gural A,Saban R,Lebel E,Gatt ME

更新日期：2019-01-01 00:00:00

abstract：:Drug-induced immune hemolytic anemia is a rare but underdiagnosed and potentially fatal condition. We report a case of severe hemolytic anemia induced by cefoxitin in a 45-year-old woman admitted with menometrorrhagia. Hemoglobin levels reached a nadir of 4.7 g/dl approximately 72 h after cefoxitin initiation, and hem...

journal_title：Acta haematologica

authors： Leaf DE,Langer NB,Markowski M,Garratty G,Diuguid DL

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:Adherence to tyrosine kinase inhibitor treatment is a significant factor in the achievement of a good clinical response in chronic myeloid leukemia (CML). The aim of this retrospective study is to investigate 1- and 2-year medication adherence to imatinib treatment, linking adherence rates with the clinical o...

journal_title：Acta haematologica

authors： Santoleri F,Lasala R,Ranucci E,La Barba G,Di Lorenzo R,Vetrò A,Di Bartolomeo P,Costantini A

更新日期：2016-01-01 00:00:00

abstract：:95 of 1,019 (9.3%) sera with monoclonal immunoglobulins (MIg) were found to have cold-reacting lymphocytotoxins (LCT). There was no difference in the prevalence of LCT in multiple myeloma, macroglobulinemia, cancer, lymphoma or benign monoclonal gammopathy. Prevalence of LCT was similar in various classes and types of...

journal_title：Acta haematologica

authors： Pruzanski W,Capes H,Ramirez G,Falk J

更新日期：1985-01-01 00:00:00

abstract：:Treatment of acute lymphoblastic leukemia is unsatisfactory in adults due to disease and patient-related factors and probably because adult chemotherapy regimens are weaker than pediatric protocols. Worries about inadequacy of adult regimens urged many hematologists, including us, to reconsider their routine treatment...

journal_title：Acta haematologica

authors： Buyukasik Y,Acar K,Kelkitli E,Uz B,Serefhanoglu S,Ozdemir E,Pamukcuoglu M,Atay H,Bektas O,Sucak GT,Turgut M,Aksu S,Yagci M,Sayınalp N,Ozcebe OI,Goker H,Haznedaroglu IC

更新日期：2013-01-01 00:00:00

abstract：:Scanning electron microscopy has shown a typical cell surface morphology in hairy cell leukemia. Scanning immunoelectron microscope techniques, utilizing monoclonal antibodies and colloidal gold particles, have recently become available. Eight patients with hairy cell leukemia have been studied with a panel of monoclo...

journal_title：Acta haematologica

authors： Soligo D,Lambertenghi-Deliliers G,Nava MT,Polli N,Cattoretti G,Polli EE

更新日期：1985-01-01 00:00:00

abstract：:The course and management of avascular necrosis of the femoral head (AVNFH) in six hips of 5 sickle cell syndrome patients (3 with Hb SS, 1 with Hb SC and 1 with Hb S/beta+-thalassaemia) are described. Two patients (aged 13 and 17 years) presented with Perthes- and osteochondritis dessicans-type lesions. These hips pr...

journal_title：Acta haematologica

authors： Rand C,Pearson TC,Heatley FW

更新日期：1987-01-01 00:00:00

abstract：:Herein, we describe a case of a female patient in whom B cell chronic lymphocytic leukemia (CLL) and mantle cell lymphoma (MCL) were diagnosed simultaneously. She presented with anemia, thrombocytopenia and splenomegaly. Flow cytometry demonstrated two immunophenotypically distinct CD5-positive monoclonal B cell popul...

journal_title：Acta haematologica

authors： Kourelis TV,Kahl BS,Benn P,Delach JA,Bilgrami SF

更新日期：2011-01-01 00:00:00

abstract：:To evaluate the effect of granulocyte/colony-stimulating factor (G-CSF) on the onset of the adult respiratory distress syndrome (ARDS), we investigated whether the incidence of ARDS due to pulmonary infection differed between the G-CSF group which received chemotherapy with G-CSF and historical controls without G-CSF....

journal_title：Acta haematologica

authors： Takahashi Y,Kobayashi Y,Chikayama S,Ikeda M,Kondo M

更新日期：1999-01-01 00:00:00

abstract：:All-trans-retinoic acid (ATRA) combined with anthracyclines is currently the standard treatment for acute promyelocytic leukemia (APL). In elderly patients the presence of comorbidities, such as cardiomyopathy or different organ failures, often represents an absolute contraindication to standard chemotherapy. In this ...

journal_title：Acta haematologica

authors： Finizio O,Pezzullo L,Rocco S,Bene L,De Rosa C,Nunziata GR,Mettivier V

更新日期：2007-01-01 00:00:00

abstract：:Neurologic complications of allogeneic hematopoietic cell transplantation (allo-HCT) include infections, cerebrovascular events, therapy-induced neurotoxicity, recurrent malignancies, and neurologic manifestations of graft-versus-host disease (GVHD). Anti-glutamic acid decarboxylase (GAD) antibody-associated cerebella...

journal_title：Acta haematologica

authors： Shargian-Alon L,Raanani P,Rozovski U,Siegal T,Yust-Katz S,Yeshurun M

更新日期：2019-01-01 00:00:00

abstract：:The thrombogenicity of prothrombin complex concentrates (PCCs) has been known as a risk factor since their first clinical use about 30 years ago. The development of in vivo models to define the thrombogenic components in PCCs was instrumental in providing a logical basis for selecting in vitro assays to screen for the...

journal_title：Acta haematologica

authors： MacGregor I,McLaughlin L,Drummond O,Prowse C,Ferguson J

更新日期：1995-01-01 00:00:00

abstract：:Low-dose cytosine arabinoside (ARA-C) induced complete remissions in 6 of 10 patients with acute non-lymphocytic leukaemia (ANLL) who were either refractory to combination chemotherapy with anthracyclines and conventional doses of ARA-C, or were in relapse. Three patients relapsed after 4, 19, and 20 months, whereas 3...

journal_title：Acta haematologica

authors： Krogh Jensen M,Stentoft J

更新日期：1986-01-01 00:00:00

abstract：:Fourteen patients with hematologic neoplasia (11 acute myeloid leukemias, 2 non-Hodgkin's lymphomas and 1 blast crisis of chronic myeloid leukemia) who underwent high-dose cytosine arabinoside (HIDARAC) therapy with or without sequential asparaginase (ASNase) were investigated in order to evaluate liver toxicity and a...

journal_title：Acta haematologica

authors： Marra R,Pagano L,De Stefano V,Leone G,Bizzi B

更新日期：1986-01-01 00:00:00

abstract：:A rare case of acute promyelcytic leukemia (APL) is reported in a 7-year-old boy. The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis. The bleeding diathesis in the case...

journal_title：Acta haematologica

authors： Engelhard D,Yatziv S,Rachmilewitz EA,Polliack A

更新日期：1979-01-01 00:00:00

abstract：:In 5 patients with mixed cryoglobulinemia, 3 with Waldenström's disease and 2 with essential cryoglobulinemia, a C1-inhibitor (C1-INH) deficiency was discovered. The complement profile was characteristic of the acquired type: the total hemolytic activity and the early components were reduced, C3 was diminished in 1 pa...

journal_title：Acta haematologica

authors： Casali P,Borzini P,Pioltelli P,Invernizzi F,Zanussi C

更新日期：1978-01-01 00:00:00

abstract：:High-dose gammaglobulin therapy for patients with idiopathic thrombocytopenic purpura (ITP), introduced by Imbach et al., was applied to 5 adults with chronic refractory ITP to investigate the mechanism of the increase in platelet counts. In 4 of the 5 cases, transient increase in platelet count was observed. Platelet...

journal_title：Acta haematologica

authors： Kurata Y,Tsubakio T,Yonezawa T,Tarui S

更新日期：1983-01-01 00:00:00

abstract：:We studied 14 adult patients presenting with fever and cytopenia of the peripheral blood and histiocytic hyperplasia with hemophagocytosis (HHH) in the bone marrow regarding an association of cytomegalovirus (CMV) and Epstein-Barr virus (EBV) by using in situ hybridization (ISH) and also evaluated the clinical and lab...

journal_title：Acta haematologica

authors： Han K,Kim Y,Kahng J,Lee J,Moon Y,Kang C,Shim S

更新日期：1996-01-01 00:00:00

abstract：:A study was carried out of 332 babies suffering from severe neonatal jaundice who were admitted to the General Hospital, Kuala Lumpar, Malaysia. Of the 332 neonates, 51 were premature and 281 were full-term babies, 178 (110 Chinese, 58 Malay, 9 Indian and 1 European-Pakistani) had bilirubin levels of 20 mg% or higher,...

journal_title：Acta haematologica

authors： Lie-Injo LE,Virik HK,Lim PW,Lie AK,Ganesan J

更新日期：1977-01-01 00:00:00

abstract：:Using labelled erythrocytes and human serum albumin, the volume of circulating erythrocytes and plasma was determined in the spleen and individual parts of the skeleton of mice under physiological conditions and 48 h after X-irradiation with a dose of 2,87 Gy. The results are significant for the interpretation of the ...

journal_title：Acta haematologica

authors： Vácha J,Holá J,Dungel J,Znojil V

更新日期：1980-01-01 00:00:00

abstract：:Haemoglobin synthesis was studied in bone marrow erythroblasts and in reticulocytes of 4 children with beta O-thalassaemia major and of 7 children with beta +-thalassaemia major. In patients with beta O-thalassaemia the gamma/a ratio was found to be lower in bone marrow than in peripheral blood. On the contrary, in pa...

journal_title：Acta haematologica

authors： Musumeci S,Schilirò G,Romeo MA,Pizzarelli G,Fischer A,Russo G

更新日期：1981-01-01 00:00:00

abstract：:Dihydrofolate reductase (FH2-R) was studied cytochemically in the bone marrow erythroblasts of 20 normal controls and 46 patients with myelodysplastic syndromes (MDSs) classified according to FAB, prior to therapy. The reaction product was quantified for the same samples with a Vickers M86 microdensitometer. The enzym...

journal_title：Acta haematologica

authors： Nano R,Invernizzi R,Rezzani R,Gerzeli G

更新日期：1988-01-01 00:00:00

abstract：:Low-risk patients with myelodysplastic syndromes (MDS) are inclined to long-term accumulation of iron in the organs due mostly to red blood cell transfusion and ineffective erythropoiesis. The effect of free toxic iron species in the liver and heart sites is well known, but recent knowledge assumes that oxidant-mediat...

journal_title：Acta haematologica

authors： Pilo F,Caocci G,Mele G,La Nasa G

更新日期：2020-10-02 00:00:00

abstract：:Cardiac scintigraphy has been performed in 60 beta-thalassaemia major patients aged 8-35 years who received regular blood transfusions and subcutaneous desferrioxamine (DFX) chelation. Fifty-seven showed no clinical, radiological or electrocardiographic evidence of heart disease and 3 had clinically apparent cardiac f...

journal_title：Acta haematologica

authors： Aldouri MA,Wonke B,Hoffbrand AV,Flynn DM,Ward SE,Agnew JE,Hilson AJ

更新日期：1990-01-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorders (PTLD) are a potentially life-threatening complication of immunosuppression in transplant recipients. The majority of cases are Epstein-Barr virus-associated lesions of B cell origin. T cell PTLD is rare, particularly in pediatric patients. We present an unusual case of mon...

journal_title：Acta haematologica

authors： Kraus TS,Twist CJ,Tan BT

更新日期：2014-01-01 00:00:00

abstract：:Janus kinases are critical components of signaling pathways that regulate hematopoiesis. Mutations of the non-receptor tyrosine kinase JAK2 are found in many BCR-ABL-negative myeloproliferative neoplasms. Preclinical results support that JAK2 inhibitors could show efficacy in treating chronic myeloproliferative neopla...

journal_title：Acta haematologica

authors： Ringel F,Kaeda J,Schwarz M,Oberender C,Grille P,Dörken B,Marque F,Manley PW,Radimerski T,le Coutre P

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:In 2003, oral fludarabine was introduced in the USA for the treatment of patients with hematologic malignancies as an alternative to its intravenous (i.v.) formulation; in 2008, it was introduced in México while the i.v. formulation was withdrawn. Accordingly, i.v. fludarabine had to be replaced by oral flud...

journal_title：Acta haematologica

authors： Velázquez-Sánchez-de-Cima S,Zamora-Ortiz G,Hernández-Reyes J,Rosales-Durón AD,González-Ramírez MP,Martagón-Herrera NA,Ruiz-Delgado GJ,Ruiz-Argüelles GJ

更新日期：2014-01-01 00:00:00

abstract：:In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and pro...

journal_title：Acta haematologica

authors： Bhargava M,Sanyal SK,Thapar MK,Kumar S,Hooja V

更新日期：1976-01-01 00:00:00