Clinical characteristics, biological profile, and outcome of biphenotypic acute leukemia: a case series.

abstract：:Cancer patients not undergoing treatment and without a history of venous thrombosis do not, as a general rule, require prophylaxis. However, venous thromboembolism is of sufficient magnitude in patients undergoing treatment for cancer for thromboprophylaxis to be routinely employed. The mainstay of primary prevention ...

journal_title：Acta haematologica

authors： Thodiyil PA,Walsh DC,Kakkar AK

更新日期：2001-01-01 00:00:00

abstract：:Avascular necrosis (AVN) of the hip is a common cause of morbidity in sickle cell disease (SCD). Its prevalence increases with age and predisposing factors include coexistent alpha-thalassemia trait, frequent vaso-occlusive crisis and a high hematocrit (Hct). SCD is relatively mild among Kuwaiti patients because of th...

journal_title：Acta haematologica

authors： Adekile AD,Gupta R,Yacoub F,Sinan T,Al-Bloushi M,Haider MZ

更新日期：2001-01-01 00:00:00

abstract：:95 of 1,019 (9.3%) sera with monoclonal immunoglobulins (MIg) were found to have cold-reacting lymphocytotoxins (LCT). There was no difference in the prevalence of LCT in multiple myeloma, macroglobulinemia, cancer, lymphoma or benign monoclonal gammopathy. Prevalence of LCT was similar in various classes and types of...

journal_title：Acta haematologica

authors： Pruzanski W,Capes H,Ramirez G,Falk J

更新日期：1985-01-01 00:00:00

abstract：:Monosomy 7 myelodysplasia is a rare hematological entity and is associated with morphological abnormalities in bone marrow and peripheral smear, and poor prognosis in children. We describe 2 children with infantile monosomy 7 myelodysplasia which evolved to leukemia. One of them died after 1 month, and the other is st...

journal_title：Acta haematologica

authors： Yeşilipek MA,Lüleci G,Velipaşaoğlu S,Berker S,Yeğin O

更新日期：1994-01-01 00:00:00

abstract：:The Philadelphia chromosome-negative myeloproliferative disorders (MPDs) polycythemia vera (PV), essential thrombocytosis (ET) and primary myelofibrosis (PMF) are characterized by increased proliferation of terminally differentiated myeloid cells. Although these disorders were recognized as clonal hematopoietic stem c...

journal_title：Acta haematologica

authors： Koppikar P,Levine RL

更新日期：2008-01-01 00:00:00

abstract：:Thrombopoietin levels in thrombocytopenic mice assayed by 75Se-se-lenomethionine incorporation into blood platelets reached a maximum 12 h after the induction of an acute, immune thrombocytopenia; that was more than twice the value in control mice. The implications of this finding are discussed with reference to the k...

journal_title：Acta haematologica

authors： Nakeff A,Roozendaal KJ

更新日期：1975-01-01 00:00:00

abstract：:This report describes a case of hairy cell leukemia (HCL) occurring with autoimmune chronic active hepatitis (CAH). A 74-year-old woman presented with typical clinical and histologic features of HCL for which splenectomy was performed. 2 years later she developed abnormal liver function tests due to auto-immune CAH. T...

journal_title：Acta haematologica

authors： Begley CG,Mackay IR,Bhathal PS

更新日期：1985-01-01 00:00:00

abstract：:Malaria parasites growing inside human erythrocytes differ from mammalian cells in their mode of acquisition of bioavailable iron and in their susceptibility to the antiproliferative action of iron chelators. We have assessed here three major properties associated with these phenomena: (a) the stage-dependent nature o...

journal_title：Acta haematologica

authors： Cabantchik ZI,Glickstein H,Golenser J,Loyevsky M,Tsafack A

更新日期：1996-01-01 00:00:00

abstract：:Premature neonates require blood transfusions, and biological parents may wish to be directed donors. Biological mothers pose a potential danger because their plasma may contain antibodies that will react with blood cell antigens inherited by the infant from the father. We studied 25 healthy, pregnant women at the tim...

journal_title：Acta haematologica

authors： Elbert C,Strauss RG,Barrett F,Goeken NE,Pittner B,Cordle D

更新日期：1991-01-01 00:00:00

abstract：:Preliminary results from the first 21 patients of a group of 30 with International Federation of Gynaecology and Obstetrics (FIGO) stage II-IV epithelial ovarian carcinoma and anaemia are reported. Patients entered this open-label, comparative-group, out-patient study and were randomized to receive conventional suppor...

journal_title：Acta haematologica

authors： James RD,Wilkinson PM,Belli F,Welch R,Cowan R

更新日期：1992-01-01 00:00:00

abstract：:Plasma samples from patients with disseminated intravascular coagulation (DIC) associated with acute promyelocytic leukemia (APL) exhibited higher levels of the D-fragment of fibrin and fibrinogen degradation products [FDP(D)], with relatively lower levels of cross-linked fibrin degradation products (XDP), than sample...

journal_title：Acta haematologica

authors： Okajima K,Koga S,Okabe H,Inoue M,Takatsuki K

更新日期：1989-01-01 00:00:00

abstract：:A hypercoagulable state has been described in thalassemia patients, partly due to a deficiency of inhibitors, protein C (PC) in particular. Since a potential role of a new hemostatic factor named protein Z (PZ) has been reported in hypercoagulability, we evaluated plasma PZ and PC levels in thalassemia and their possi...

journal_title：Acta haematologica

authors： Del Vecchio GC,Nigro A,Giordano P,Schettini F,Altomare M,Pietrapertosa A,De Mattia D

更新日期：2007-01-01 00:00:00

abstract：:To characterize intracellular signaling in peripheral blood (PB) cells of acute myeloid leukemia (AML) patients undergoing pretransplant conditioning with CXCR4 inhibitor plerixafor, granulocyte colony-stimulating factor (G-CSF), and busulfan plus fludarabine (Bu+Flu) chemotherapy, we profiled 153 proteins in 33 funct...

journal_title：Acta haematologica

authors： Zeng Z,Liu W,Benton CB,Konoplev S,Lu H,Wang RY,Chen J,Shpall E,Baggerly KA,Champlin R,Konopleva M

更新日期：2019-01-01 00:00:00

abstract：:The first 2 Canadian cases of combinations of Hb D Los Angeles and beta-thalassaemia were found in an Italian family and an East Indian family in Hamilton, Ont. The structure of the Hb D variant was identified by radioimmunoassay. The beta +-thalassaemia trait in the Italian family and the beta o-thalassaemia trait in...

journal_title：Acta haematologica

authors： Wong SC,Ali MA

更新日期：1980-01-01 00:00:00

abstract：:Primary plasma cell leukemia (PCL) is a rare form of plasma cell neoplasm with a poor prognosis. Conventional melphalan-based treatments have been most disappointing. We report the case of a 62-year-old man with a primary form of PCL treated with VAD combination achieving an objective response, and who received high-d...

journal_title：Acta haematologica

authors： Panizo C,Rifón J,Rodríguez-Wilhelmi P,Cuesta B,Rocha E

更新日期：1999-01-01 00:00:00

abstract：:It was confirmed that activation of the kallikrein-kinin enzyme system in cryoglobulinemia might be initiated by activation of factor XII to factor XIIa by cryoglobulin. It was also demonstrated that cryoglobulin or fibrin clots lost their ability to redissolve on warming to 37 degrees C, and consequently the lysis ti...

journal_title：Acta haematologica

authors： Kataoka K,Yamada S,Toki N

更新日期：1984-01-01 00:00:00

abstract：:Coagulation factor VIII inhibitor arising in a patient with autoimmune disease was immunologically analyzed. A 63-year-old man who had been diagnosed as suffering from polyarteritis nodosa was treated with prednisolone for 10 years. Severe bleeding tendency developed and coagulation studies demonstrated a high titer o...

journal_title：Acta haematologica

authors： Okamura T,Yamauchi Y,Fukuda T,Suehiro K,Murakawa M,Shibuya T,Nagasawa K,Harada M,Niho Y

更新日期：1991-01-01 00:00:00

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00

abstract：:Agranulocytosis developed in a 20-year-old Greek patient with beta-thalassaemia major, 11 weeks after commencing chelation with the oral iron chelator 1,2-dimethyl-3-hydroxypyrid-4-one (L1) and 6 weeks after receiving the drug at a total daily dose of 105 mg/kg. The patient presented with generalised weakness, low-gra...

journal_title：Acta haematologica

authors： al-Refaie FN,Veys PA,Wilkes S,Wonke B,Hoffbrand AV

更新日期：1993-01-01 00:00:00

abstract：:Two subjects, not previously reported in detail, had severe inherited deficiencies of erythrocyte pyrimidine nucleotidase. This was manifested hematologically by moderate hemolytic anemia with splenomegaly, morphologically by punctate basophilic stippling of Wright's stained erythrocytes, and biochemically by intraery...

journal_title：Acta haematologica

authors： Paglia DE,Fink K,Valentine WN

更新日期：1980-01-01 00:00:00

abstract：:Upper-extremity deep venous thrombosis (UEDVT) is an increasingly important clinical problem in children. These events are classified as primary or secondary, with the latter being the most common and usually associated with the presence of a central venous line. Among primary UEDVT, the so-called Paget-Schroetter syn...

journal_title：Acta haematologica

authors： Brandão LR,Williams S,Kahr WH,Ryan C,Temple M,Chan AK

更新日期：2006-01-01 00:00:00

abstract：:In a comparison of 47 patients with Philadelphia-chromosome (Ph)-positive chronic myeloid leukemia (CML) in the Nagasaki University School of Medicine and 64 patients with the same disease in the Roswell Park Memorial Institute, the correlation between the modal number of chromosomes and the therapeutic response and/o...

journal_title：Acta haematologica

authors： Sadamori N,Yao E,Mine M,Tokunaga S,Matsunaga M,Nakamura H,Sasagawa I,Itoyama T,Hayashibara T,Sandberg AA

更新日期：1992-01-01 00:00:00

abstract：:A patient developed a drug rash and neutropenia while receiving tobramycin, ticarcillin and flucloxacillin intravenously for osteomyelitis. Incorporation of these antibiotics into in vitro cultures of bone marrow granulocyte macrophage precursors (CFU-C) showed no inhibition of the patient's marrow or normal marrow by...

journal_title：Acta haematologica

authors： Irvine AE,Morris TC,Kelly GJ,McCracken N

更新日期：1983-01-01 00:00:00

abstract：:Granulocytic sarcoma of the small intestine preceding or as the presenting feature of acute myelogenous leukemia with chromosome 16 abnormalities has been observed in at least 4 patients. We report the case of a patient initially diagnosed with eosinophilic gastroenteritis, responding to corticosteroid treatment for 2...

journal_title：Acta haematologica

authors： Julia A,Nomdedeu JF

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVE:We investigated the prevalence of opportunistic infections in HIV-infected women according to transferrin (TF) phenotype. METHODS:We conducted a cross-sectional study among 200 HIV-positive women in the Butare University Teaching Hospital in Rwanda. TF phenotypes were determined using starch gel electrophore...

journal_title：Acta haematologica

authors： Masaisa F,Gahutu JB,Mukiibi J,Delanghe J,Philippé J

更新日期：2012-01-01 00:00:00

abstract：:A 3-year-old child developed severe aplastic anaemia following hepatitis A. Since no HLA-compatible donor was available, he was treated with oxymetholone, antithymocytic globulin and methylprednisolone, but no haematologic recovery was observed and he consequently died of pneumonia. Although the association of aplasti...

journal_title：Acta haematologica

authors： Doménech P,Palomeque A,Martínez-Gutiérrez A,Viñolas N,Vela E,Jiménez R

更新日期：1986-01-01 00:00:00

abstract：:Aspirates from bone marrow, spleen and liver were morphologically analysed in 15 untreated patients wich chronic myeloid leukaemia. Megaloblastic changes of the erythroblasts were found to be more common in the spleen and liver than in the bone marrow. A significant increase of 'erythroblastic islands', i.e. erythrobl...

journal_title：Acta haematologica

authors： Sjögren U

更新日期：1976-01-01 00:00:00

abstract：:We have been studying hematopoietic effects by the tachykinins, which like many other neuropeptides can be expressed in neural and nonneural tissues. Substance P (SP) and neurokinin-A (NK-A), members of the tachykinins are immune and hematopoietic modulators. SP and NK-A are derived from the preprotachykinin-I gene (P...

journal_title：Acta haematologica

authors： Rameshwar P,Gascón P

更新日期：1997-01-01 00:00:00

abstract：:It has been found possible to test ferritin concentrations in the reticulum and hemopoietic cells from human bone marrow by an immunoradiometric assay. Ferritin concentration in healthy test persons amounts to 0.92 +/- 0.38 ng/microgram protein in the reticulum and 0.084 +/- 0.031 ng/microgram protein in hemopoietic c...

journal_title：Acta haematologica

authors： Oertel J,Stephan M,Kastner M

更新日期：1982-01-01 00:00:00

abstract：:During a screening for hemoglobinopathies, we found a carrier of the Sardinian δβ-thalassemia condition. The proband's hematology and hemoglobin (Hb) profile agreed with those of the other carriers previously identified during our diagnostic program except for the fetal Hb (HbF) composition, which consisted of both α2...

journal_title：Acta haematologica

authors： Trova S,Mereu P,Cocco E,Masala B,Manca L,Pirastru M

更新日期：2016-01-01 00:00:00