Myelodysplastic syndrome preceding acute myelomonocytic leukemia with dysplastic marrow eosinophilia and inv(16).

abstract：:Granulocytic sarcoma (GS) is a rare extramedullary tumor composed of immature myeloid cells. It is usually associated with leukemia or other myeloproliferative disorders, but can also occur without overt hematologic disease, i.e. in patients with a normal bone marrow and no history of acute myelogenous leukemia. This ...

journal_title：Acta haematologica

authors： Breccia M,Petti MC,Fraternali-Orcioni G,Monarca B,Latagliata R,D'Elia GM,Mandelli F,Pileri SA

更新日期：2000-01-01 00:00:00

abstract：:We evaluated the iron status of 50 Sicilian patients with G6PD deficiency under steady-state conditions and compared our results with those for 50 control patients. We studied haemolysis and iron indices to evaluate the iron balance. These patients could be considered to be at risk of iron overload as a result of incr...

journal_title：Acta haematologica

authors： Ragusa R,Di Cataldo A,Gangarossa S,Lo Nigro L,Schilirò G

更新日期：1993-01-01 00:00:00

abstract：:Hypercalcemia is a significant feature of patients with active multiple myeloma (MM) with extensive bone disease. Among the causes of non-neoplastic hypercalcemia, primary hyperparathyroidism (PHPT) is one of the most common, leading to osteoporosis and bone fractures. Interestingly, some preclinical data indicate tha...

journal_title：Acta haematologica

authors： Notarfranchi L,Marchica V,Dalla Palma B,Pelagatti L,Burroughs-Garcia J,Pedrazzoni M,Ruffini L,Cetani F,Marcocci C,Giuliani N

更新日期：2020-09-09 00:00:00

abstract：:Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a rare lymphoproliferative disorder characterized by diffuse lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, and polyclonal hypergammaglobulinemia. Morphologically, the involved lymph nodes demonstrate complete effacement of the normal arch...

journal_title：Acta haematologica

authors： Sallah S,Gagnon GA

更新日期：1998-01-01 00:00:00

abstract：:Fas/APO-1 (CD95) is a cell surface molecule that can transduce apoptotic signals into cells. We examined the expression of Fas antigen on CD4+ and CD8+ T cells of patients who received total body irradiation (TBI) as a preparative regimen for allogeneic bone marrow transplantation. Numbers of peripheral blood lymphocy...

journal_title：Acta haematologica

authors： Fujimori Y,Saheki K,Itoi H,Okamamoto T,Kakishita E

更新日期：2000-01-01 00:00:00

abstract：:A 56-year-old male presented with inguinal lymphadenopathy and leucocytosis (WBC 98 x 10(9)/l). Bone marrow morphology showed myeloid hyperplasia, with eosinophilia. Cytogenetic analysis showed no evidence of the Philadelphia chromosome, and fluorescence in situ hybridisation studies for the BCR/ABL fusion were negati...

journal_title：Acta haematologica

authors： JabbarAl-Obaidi M,Rymes N,White P,Pomfret M,Smith H,Starczynski J,Johnson R

更新日期：2002-01-01 00:00:00

abstract：:To assess the effect of prophylactic treatment with antithymocyte globulin (ATG) on graft-versus-host disease (GvHD) in myeloablative transplant patients, we performed a meta-analysis of randomized and cohort studies. Medline, Embase, the Cochrane Controlled Trial Register and the Science Citation Index were searched ...

journal_title：Acta haematologica

authors： Sheng Z,Ma H,Pang W,Niu S,Xu J

更新日期：2013-01-01 00:00:00

abstract：:A 69-year-old woman presented with chronic lymphocytic leukemia (CLL) diagnosed after bone marrow recovery following intensive chemotherapy for acute lymphoblastic leukemia. The retrospective diagnosis of initial blastic transformation of CLL was made. The patient eventually died, 5 months after initial blastic phase,...

journal_title：Acta haematologica

authors： Archimbaud E,Charrin C,Gentilhomme O,Rimokh R,Guyotat D,Fiere D,Germain D

更新日期：1988-01-01 00:00:00

abstract：:Dihydrofolate reductase (FH2-R) was studied cytochemically in the bone marrow erythroblasts of 20 normal controls and 46 patients with myelodysplastic syndromes (MDSs) classified according to FAB, prior to therapy. The reaction product was quantified for the same samples with a Vickers M86 microdensitometer. The enzym...

journal_title：Acta haematologica

authors： Nano R,Invernizzi R,Rezzani R,Gerzeli G

更新日期：1988-01-01 00:00:00

abstract：:The maturation process of leukemic myelomonocytoid cells derived from peripheral blood of two typical cases of chronic myelomonocytic leukemia was investigated in vitro. In both cases, liquid culture of the leukemic cells in the presence or absence of 12-o-tetradecanoyl phorbol-13-acetate yielded either monocyte-macro...

journal_title：Acta haematologica

authors： Takuwa N,Kanegasaki S,Asano S,Tomita T,Nakayama E,Sato N,Shinohara T,Miwa S

更新日期：1984-01-01 00:00:00

abstract：:Natural killer (NK) cell activity against K562 cell targets and the distribution of T cell subpopulations were investigated in the peripheral blood of 25 patients affected by beta thalassemia major, 18 clinically healthy heterozygotes, and 25 age-matched normal subjects. It was found that thalassemia major patients di...

journal_title：Acta haematologica

authors： Neri A,Brugiatelli M,Iacopino P,Callea V,Ronco F

更新日期：1984-01-01 00:00:00

abstract：:Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support hematopoietic differentiation of allogeneic cord blood cells in ...

journal_title：Acta haematologica

authors： Thalmeier K,Meissner P,Moosmann S,Sagebiel S,Wiest I,Huss R

更新日期：2001-01-01 00:00:00

abstract：:Agranulocytosis is a rare side effect of phenytoin treatment. We describe the case of an elderly man who developed agranulocytosis 2 weeks following initiation of phenytoin treatment, on no cytotoxic drugs or any other medications except decadron. The white blood cell count was 300/mm3 with absent granulocytes. The li...

journal_title：Acta haematologica

authors： Sharafuddin MJ,Spanheimer RG,McClune GL

更新日期：1991-01-01 00:00:00

abstract：:We evaluated an enzyme-linked immunosorbent assay (ELISA) for embryonic zeta-globin chains as a routine screening test for (--(SEA)) alpha-thalassemia deletion (SEA deletion). A total of 174 consecutive patient samples with a request for Hb analysis were recruited. The ELISA method was evaluated against a polymerase c...

journal_title：Acta haematologica

authors： Ma SK,Ma V,Chan AY,Chan LC,Chui DH

更新日期：2002-01-01 00:00:00

abstract：:A 28-year-old woman with Bence-Jones multiple myeloma (MM) presented with several osteolytic lesions and a massive bone marrow infiltration with mature plasmocytes. After 6 cycles of chemotherapy with melphalan and prednisone, the patient, in apparent clinical remission, underwent allogeneic bone marrow transplantatio...

journal_title：Acta haematologica

authors： Gallamini A,Buffa F,Bacigalupo A,Van Lint MT,Peralvo J,Pittaluga PA,Occhini D,Marmont AM

更新日期：1987-01-01 00:00:00

abstract：:Basic fibroblast growth factor (b-FGF) mediates a variety of biological responses such as angiogenesis and hematopoiesis. We examined the effect of b-FGF on human neutrophil functions in vitro. The surface expression of effector cell molecules on neutrophils was determined by flow cytometry and monoclonal antibodies. ...

journal_title：Acta haematologica

authors： Takagi S,Takahashi K,Katsura Y,Matsuoka T,Ohsaka A

更新日期：2000-01-01 00:00:00

abstract：:A 74-year-old woman was treated by lithium carbonate 3 x 300 mg per day for drug-induced aplastic anemia. After 8 days, she suddenly developed severe impairment of consciousness with myoclonias and hypertonia which persisted during 10 days despite lithium withdrawal and sodium chloride infusion. Slight disorders of wa...

journal_title：Acta haematologica

authors： Efira A,van Laethem Y,Ectors M,Unger J

更新日期：1980-01-01 00:00:00

abstract：:A case of acute leukaemia with t(4;11) chromosomal abnormality in a 28-year-old woman is reported. At diagnosis, two blast cell populations were seen: 60% of the cells were small cells with lymphoid morphology, 40% were large cells with monocytic morphology. Cytochemical examination was consistent with acute myeloid l...

journal_title：Acta haematologica

authors： Campos L,Espinouse D,Felman P,Charrin C,Gentilhomme O,Germain D

更新日期：1986-01-01 00:00:00

abstract：:This study was undertaken to define to which platelet components 75Se-methionine is bound after its injection to normal rats, and to study the curves of specific radioactivity of each labelled fraction. It has been shown that, for a part, platelet labelling is due to adsorption of plasma proteins (albumin and fibrinog...

journal_title：Acta haematologica

authors： Dassin E,Najean Y

更新日期：1979-01-01 00:00:00

abstract：:The first 2 Canadian cases of combinations of Hb D Los Angeles and beta-thalassaemia were found in an Italian family and an East Indian family in Hamilton, Ont. The structure of the Hb D variant was identified by radioimmunoassay. The beta +-thalassaemia trait in the Italian family and the beta o-thalassaemia trait in...

journal_title：Acta haematologica

authors： Wong SC,Ali MA

更新日期：1980-01-01 00:00:00

abstract：:Posttransplant lymphoproliferative disorders (PTLD) are a potentially life-threatening complication of immunosuppression in transplant recipients. The majority of cases are Epstein-Barr virus-associated lesions of B cell origin. T cell PTLD is rare, particularly in pediatric patients. We present an unusual case of mon...

journal_title：Acta haematologica

authors： Kraus TS,Twist CJ,Tan BT

更新日期：2014-01-01 00:00:00

abstract：:A comparative study of karyotypes, hematological variables and neutrophil alkaline phosphatase (NAP) was performed in 106 parents (53 couples) of children with free, homogeneous trisomy 21 and of 220 parents (110 couples) of normal children. In the parents of trisomy 21 children we found a significant increase of the ...

journal_title：Acta haematologica

authors： Grozdea J,Bourrouillou G,Mounie C,Colombies P

更新日期：1980-01-01 00:00:00

abstract：:The effects of lithium on the microtubular and microfilament systems of neutrophil granulocytes is described. The phagocytic capacity of human neutrophils was reduced or inhibited by using vinblastine or cytochalasin B. Lithium at concentrations ranging from 0.5 to 2.0 mEq/l proved to be capable of antagonising the ac...

journal_title：Acta haematologica

authors： Carulli G,Marini A,Azzarà A,Petrini M,Ruocco L,Ambrogi F

更新日期：1985-01-01 00:00:00

abstract：:We have retrospectively analyzed a series of 19 patients with hepatitis C virus (HCV) infection and chronic thrombocytopenia not attributable to hypersplenism or to other causes. Antiplatelet antibodies were present in 81% of cases. Response to prednisone was observed in 6 of 7 patients and 1 of 3 patients responded t...

journal_title：Acta haematologica

authors： Hernández F,Blanquer A,Linares M,López A,Tarín F,Cerveró A

更新日期：1998-01-01 00:00:00

abstract：:It has been found possible to test ferritin concentrations in the reticulum and hemopoietic cells from human bone marrow by an immunoradiometric assay. Ferritin concentration in healthy test persons amounts to 0.92 +/- 0.38 ng/microgram protein in the reticulum and 0.084 +/- 0.031 ng/microgram protein in hemopoietic c...

journal_title：Acta haematologica

authors： Oertel J,Stephan M,Kastner M

更新日期：1982-01-01 00:00:00

abstract：:Platelet aggregation in citrated and heparinized plasma by ionophore A 23187 and Ristocetin was studied in normal subjects and in patients with von Willebrand's disease and congenital afibrinogenemia. Aggregation by ionophore was normal in all groups both in citrated and heparinized plasma. Aggregation by Ristocetin i...

journal_title：Acta haematologica

authors： Girolami A,Fabris F,Marco L,Peruffo R

更新日期：1976-01-01 00:00:00

abstract：:Immunologic abnormalities have been described in patients with Hodgkin lymphoma, including autoimmune hemolytic anemia and immune thrombocytopenic purpura. The concurrent diagnoses of Hodgkin lymphoma and acquired aplastic anemia, however, is extremely rare. We report a 56-year-old Japanese female patient with severe ...

journal_title：Acta haematologica

authors： Saitoh T,Matsushima T,Yamane A,Sakuraya M,Irisawa H,Yokohama A,Handa H,Tsukamoto N,Karasawa M,Nojima Y,Murakami H

更新日期：2007-01-01 00:00:00

abstract：:Acute megakaryoblastic leukemia is uncommon and comprises about 5% of acute nonlymphoid leukemias in the French-American-British classification. Cell lines from such leukemias are relatively rare with only about 8 reported in the literature. We established a cell line from a case of acute megakaryoblastic leukemia ari...

journal_title：Acta haematologica

authors： Skinnider LF,Pabello P,Zheng CY

更新日期：1997-01-01 00:00:00

abstract：:Pyrimidine 5'-nucleotidase (P5'N) partial deficiency has been described in several hematological disorders and also in the beta-thalassemic trait. To check if the P5'N deficiency in thalassemia was acquired we used thalassemic red cells (from either homo- or heterozygous subjects), whose P5'N activity was lower than i...

journal_title：Acta haematologica

authors： David O,Vota MG,Piga A,Ramenghi U,Bosia A,Pescarmona GP

更新日期：1989-01-01 00:00:00

abstract：:In a previous study, we evaluated efficacy of repeated antilymphocyte globulin (ALG) treatment for patients with severe aplastic anemia not responding to an initial ALG treatment or relapsing after initial response to ALG. We now searched in the same cohort of patients for differences between patients who responded to...

journal_title：Acta haematologica

authors： Viollier R,Tichelli A

更新日期：2000-01-01 00:00:00