A fourth case of 8p11 myeloproliferative disorder transforming to B-lineage acute lymphoblastic leukaemia. A case report.

abstract：:Pleural effusion in chronic lymphocytic leukemia (CLL) is a relatively rare phenomenon. We report a case of a pleural effusion associated with B-cell CLL but with predominantly reactive T lymphocytes in the effusion. A cell surface phenotype study showed that T lymphocytes predominated in the pleural effusion, althoug...

journal_title：Acta haematologica

authors： Miyahara M,Shimamoto Y,Sano M,Nakano H,Shibata K,Matsuzaki M

更新日期：1996-01-01 00:00:00

abstract：:Iron deficiency is the main cause of anemia in both sexes, with women being more commonly affected. Iron therapy is currently considered an effective and safe remedy to replenish the iron storages. Iron can be administrated both orally and intravenously. In particular, intravenous (IV) iron therapy is widely used when...

journal_title：Acta haematologica

authors： Di Girolamo A,Albanesi M,Loconte F,Di Bona D,Caiaffa MF,Macchia L

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVES:Reticulated platelets circulating in the blood reflect megakaryopoietic activity and platelet turnover and can be automatically and low-invasively measured as the immature platelet fraction (IPF) using a Sysmex XN hematocytometer. The present study retrospectively investigated whether or not the IPF can pred...

journal_title：Acta haematologica

authors： Takami A,Mizuno S,Nakamura A,Kanasugi J,Yamamoto H,Vu Quang L,Nakagami Y,Nakano Y,Yamada S,Matsumura S,Takasugi S,Uchino K,Horio T,Murakami S,Oohigashi Y,Nakayama T,Tani H,Enomoto M,Hanamura I

更新日期：2020-09-17 00:00:00

abstract：:Red cell glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-chromosomal-linked abnormality often associated with hemolytic anemia. The G6PD variants obtained from 2 unrelated males, one associated with enzyme deficiency and history of hemolytic jaundice, and the other associated with enzyme deficiency but no ...

journal_title：Acta haematologica

authors： Sáenz GF,Chaves M,Berrantes A,Elizondo J,Montero AG,Yoshida A

更新日期：1984-01-01 00:00:00

abstract：:In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and pro...

journal_title：Acta haematologica

authors： Bhargava M,Sanyal SK,Thapar MK,Kumar S,Hooja V

更新日期：1976-01-01 00:00:00

abstract：:Macrothrombocytopenia (MTP) is a group of rare disorders characterized by giant platelets, thrombocytopenia, and variable association with abnormal bleeding. Inherited MTP are frequently misdiagnosed as immune thrombocytopenia. Associated second-organ manifestation can help narrow down syndromic MTPs. We describe a ca...

journal_title：Acta haematologica

authors： Karki NR,Ajebo G,Savage N,Kutlar A

更新日期：2021-01-01 00:00:00

abstract：:We describe a B cell chronic lymphocytic leukemia/lymphoma (B-CLL) patient with an adrenocortical adenoma. He was treated initially with oral cyclophosphamide and prednisolone for 2 months, followed by low-dose prednisolone for an additional 2 years, which resulted in the prompt disappearance of CLL cells. After a per...

journal_title：Acta haematologica

authors： Adachi Y,Adachi M,Hinoda Y,Fukushima H,Takahashi T,Imai K

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Argininemia is an autosomal recessive urea cycle disorder (UCD). Unlike other UCD, hyperammonemia is rarely seen. Patients usually present in childhood with neurological symptoms. Uncommon presentations like neonatal cholestasis or cirrhosis have been reported. Although transient elevations of liver transami...

journal_title：Acta haematologica

authors： Kiykim E,Zubarioglu T,Cansever MS,Celkan T,Häberle J,Aktuglu Zeybek AC

更新日期：2018-01-01 00:00:00

abstract：:Hypersensitivity vasculitis occurs in response to various exogenous agents. A case of a serum sickness syndrome with cutaneous vasculitis is described in a patient given an intravenous iron-dextran infusion. ...

journal_title：Acta haematologica

authors： Bielory L

更新日期：1990-01-01 00:00:00

abstract：:Amylase-producing tumors are mainly adenocarcinomas and, in rare instances, multiple myelomas. We describe here a first case of amylase-producing Bence Jones type myeloma with pancreatitis-like symptoms and the second in a Caucasian patient. The finding of salivary-type hyperamylasemia in a 72-year-old female with a p...

journal_title：Acta haematologica

authors： Lopez J,Ulibarrena C,Gonzalez-Porque P,Navas G,Roldan E,Cancelas JA,Perez-Oteyza J,Burgaleta C,García-Laraña J,Sastre JL

更新日期：1993-01-01 00:00:00

abstract：:Platelet-derived growth factor (PDGF) is thought to take part in the genesis of bone marrow fibrosis that can be found in patients with myeloproliferative diseases. We evaluated platelet mitogenic activity as the difference between serum and plasma activity in 8 patients with myeloproliferative disease. We observed a ...

journal_title：Acta haematologica

authors： Caenazzo A,Pietrogrande F,Polato G,Piva E,Masiero M,Sgarabotto D,Girolami A

更新日期：1989-01-01 00:00:00

abstract：:The BCR-ABL fusion gene represents the hallmark of chronic myelogenous leukemia (CML) and is derived from a translocation between chromosome 9 and 22. The majority of CML patients have a breakpoint in the major BCR region of the BCR gene giving rise to e13a2 or e14a2 BCR-ABL transcripts. Occasionally, other BCR breakp...

journal_title：Acta haematologica

authors： Vefring HK,Gruber FX,Wee L,Hovland R,Hjorth-Hansen H,Gedde Dahl T,Meyer P

更新日期：2009-01-01 00:00:00

abstract：:Thalidomide acts on the microenvironment of myelodysplastic syndromes (MDS) by influencing cytokine networks, and growing evidence supports thalidomide's usefulness in the management of haematological malignancies, such as MDS. The European Collaboration Group on Myelofibrosis with Myeloid Metaplasia reviewed patients...

journal_title：Acta haematologica

authors： Prentice HG,Sacchi S,Russell N

更新日期：2005-01-01 00:00:00

abstract：:In 83 children with acute lymphoblastic leukaemia (ALL) the immunological phenotype of the lymphoblasts was determined using E rosetting, monoclonal anti-T cell sera, surface immunoglobulin staining and common ALL antiserum. The data were compared with acid alpha-naphthyl acetate esterase (ANAE) and acid phosphatase (...

journal_title：Acta haematologica

authors： Veerman AJ,Huismans DR,van Zantwijk CH

更新日期：1983-01-01 00:00:00

abstract：:A patient with regional enteritis had received iron dextran for treatment of iron deficiency. Subsequently he developed a large (3.1 g/100 ml) IgG-K serum spike which had precipitin activity against dextran sulfate but not a variety of other antigens. There has been no evidence of multiple myeloma and the spike gradua...

journal_title：Acta haematologica

authors： Shimm DS,Cohen HJ

更新日期：1978-01-01 00:00:00

abstract：:At our hospital, 47 out of 184 consecutive splenectomies performed over 7 recent years were carried out on patients afflicted with various hematologic diseases. The results of these 47 splenectomies were the subject of a careful retrospective analysis. The majority of the splenectomies (81%) were therapeutic. Cytopeni...

journal_title：Acta haematologica

authors： Dotevall A,Kutti J,Wadenvik H,Westin J,Angerås U,Darle N

更新日期：1987-01-01 00:00:00

abstract：:A 26-year-old female with Ki-1-positive large-cell anaplastic lymphoma is reported. The neoplastic cells were phenotypically and genotypically of T cell origin. Initially, neoplastic cells invaded the skin and lymph nodes, and then invaded the sternal and vertebral bones, ribs and the iliopsoas muscle. Central nervous...

journal_title：Acta haematologica

authors： Tsukamoto N,Morita K,Maehara T,Mitsuhashi M,Karasawa M,Murakami H,Omine M,Naruse T,Yatabe H

更新日期：1992-01-01 00:00:00

abstract：:Factor VII deficiency is the least rare among uncommon congenital coagulation disorders. The majority of cases are isolated deficiencies. In some cases, FVII deficiency has been found to be associated with the deficiency in another coagulation factor or with non-coagulation-related abnormalities or defects. The evalua...

journal_title：Acta haematologica

authors： Girolami A,Ruzzon E,Tezza F,Allemand E,Vettore S

更新日期：2007-01-01 00:00:00

abstract：:We report a patient with myelodysplastic syndrome (MDS), refractory anaemia with excess blasts in transformation, in whom complete remission (CR) was achieved with the administration of granulocyte colony-stimulating factor (G-CSF). The 76-year-old patient was admitted to our hospital with a fever and a productive cou...

journal_title：Acta haematologica

authors： Kondo H,Kasahara Y,Mori A

更新日期：2002-01-01 00:00:00

abstract：:Haemoglobin synthesis was studied in bone marrow erythroblasts and in reticulocytes of 4 children with beta O-thalassaemia major and of 7 children with beta +-thalassaemia major. In patients with beta O-thalassaemia the gamma/a ratio was found to be lower in bone marrow than in peripheral blood. On the contrary, in pa...

journal_title：Acta haematologica

authors： Musumeci S,Schilirò G,Romeo MA,Pizzarelli G,Fischer A,Russo G

更新日期：1981-01-01 00:00:00

abstract：:Littoral cell angioma (LCA) is a rare vascular tumor of the spleen with an unknown etiology and unclear natural history. An association with synchronous malignancy has been described. We report the case of a 54-year-old woman who had progressive splenomegaly over 3 years following resection of a colon adenocarcinoma. ...

journal_title：Acta haematologica

authors： Steensma DP,Morice WG

更新日期：2000-01-01 00:00:00

abstract：:Two unrelated patients with Bernard-Soulier syndrome and their relatives were studied. The patients demonstrated severe bleeding diathesis, the relatives were asymptomatic. The propositi showed the characteristic abnormalities of the syndrome: thrombocytopenia, a percentage of giant platelets higher than 65%, prolonge...

journal_title：Acta haematologica

authors： De Marco L,Fabris F,Casonato A,Fabris P,Dal Ben MG,Barbato A,Girolami A

更新日期：1986-01-01 00:00:00

abstract：:Recently, a factor was discovered in the serum of hepatectomized animals which was capable of augmenting the hepatic erythropoietin response to hypoxia when injected into normal rats. This substance was localized in the liver via an in situ perfusion technique and was termed the hepatic erythropoietic factor (HEF). Pa...

journal_title：Acta haematologica

authors： Naughton BA,Liu P,Naughton GK,Gordon AS

更新日期：1983-01-01 00:00:00

abstract：:The most common single genetic disorder and a major public health issue in Greece and other Mediterranean countries is beta-thalassemia. Current therapeutic approaches for homozygous beta-thalassemia entail blood transfusions and iron chelation therapy with deferoxamine or deferiprone for preventing tissue hemosideros...

journal_title：Acta haematologica

authors： Chaidos A,Makis A,Hatzimichael E,Tsiara S,Gouva M,Tzouvara E,Bourantas KL

更新日期：2004-01-01 00:00:00

abstract：:Deficiency in glucose-6-phosphate dehydrogenase (G6PD) is the most common enzymopathy, and more than 125 different mutations causing G6PD deficiency have been identified. Chronic haemolytic anaemia (CHA) associated with G6PD deficiency is rare, but there is a cluster of mutations causing CHA between amino acids 361-42...

journal_title：Acta haematologica

authors： Hundsdoerfer P,Vetter B,Kulozik AE

更新日期：2002-01-01 00:00:00

abstract：:To test whether anti-idiotypic immunoregulation of factor VIII(FVIII)-inhibiting antibodies could be feasible in hemophiliacs, we assayed the minimal number and range of immunogenic, functional FVIII epitopes to which a series of murine anti-FVIII monoclonal antibodies (MAb) were directed. Rabbit anti-idiotypic sera t...

journal_title：Acta haematologica

authors： Tiarks CY,Humphreys RE,Pechet L

更新日期：1990-01-01 00:00:00

abstract：:We describe two kindreds of Arab ancestry characterized by multiple cases of acute lymphoblastic leukemia. Consanguinity and intermarriages were prevalent in the two families. Age, mode of presentation, characteristics of the leukemic cells, response to treatment and prognosis were remarkably similar among the patient...

journal_title：Acta haematologica

authors： Kende G,Toren A,Mandel M,Neumann Y,Kenet G,Brok-Simoni F,Ramot B,Ben-Bassat I,Rechavi G

更新日期：1994-01-01 00:00:00

abstract：:Serum folate levels and unsaturated folate-binding capacity (UFBC) in a mixed population of outpatients and inpatients were analyzed with respect to race, sex, and age. The results supported the relatively high prevalence of subnormal serum folates in patient populations, did not find lower serum folates in the elderl...

journal_title：Acta haematologica

authors： Lawrence VA

更新日期：1983-01-01 00:00:00

abstract：:We evaluated the iron status of 50 Sicilian patients with G6PD deficiency under steady-state conditions and compared our results with those for 50 control patients. We studied haemolysis and iron indices to evaluate the iron balance. These patients could be considered to be at risk of iron overload as a result of incr...

journal_title：Acta haematologica

authors： Ragusa R,Di Cataldo A,Gangarossa S,Lo Nigro L,Schilirò G

更新日期：1993-01-01 00:00:00

abstract：:A mild anemia (hemoglobin 9 g/dl) was found in a patient from Seville (Spain) with marked morphological abnormalities in the peripheral blood smear. The red cell osmotic fragility showed a mild resistance curve with a mean cell fragility (MCF) of 0.375% NaCl (normal = 0.450). Chemical Chemical and thermal instability ...

journal_title：Acta haematologica

authors： Arends T,Garlín G,Guevara JM,Amesty C,Pérez-Bández O,Lorkin PA,Lehmann H,Castillo O

更新日期：1985-01-01 00:00:00