Abstract:
:To assess the effect of prophylactic treatment with antithymocyte globulin (ATG) on graft-versus-host disease (GvHD) in myeloablative transplant patients, we performed a meta-analysis of randomized and cohort studies. Medline, Embase, the Cochrane Controlled Trial Register and the Science Citation Index were searched for studies on ATG treatment in patients with hematologic disorders undergoing myeloablative transplantation. Four randomized controlled trials, six retrospective and one prospective cohort study were included, covering 1,549 patients. The summary hazard ratios (HRs) for overall survival were 0.84.
journal_name
Acta Haematoljournal_title
Acta haematologicaauthors
Sheng Z,Ma H,Pang W,Niu S,Xu Jdoi
10.1159/000343604subject
Has Abstractpub_date
2013-01-01 00:00:00pages
146-53issue
3eissn
0001-5792issn
1421-9662pii
000343604journal_volume
129pub_type
杂志文章,meta分析,评审abstract::A rare case of Hodgkin's disease which initially presented with a thyroid tumor in an 18-year-old-man is reported. The tumor involved most of the thyroid gland but was well demarcated, and the border between the tumor and the remnants of the thyroid gland was relatively clear, suggesting secondary Hodgkin's disease in...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000203627
更新日期:1997-01-01 00:00:00
abstract::A diester lipase activity is described in human red blood cells (RBC). Diester lipase activity acts as a membrane-bound enzyme and is assayed using intact RBC as the enzyme source. An emulsion of di-[3H]-oleoylglycerol (0.6 mM) serves as the substrate. The optimum pH for the reaction is 7.8 at 37 degrees C. Lipolytic ...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000206770
更新日期:1983-01-01 00:00:00
abstract:BACKGROUND/AIMS:The study was undertaken to understand the characteristic of plasma cell leukemia (PCL) in China. METHODS:We reviewed and compared medical data of 22 primary PCL, 9 secondary PCL and 461 multiple myeloma (MM) diagnosed at our institute from January 2000 to January 2008. RESULTS:The median onset ages o...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000210555
更新日期:2009-01-01 00:00:00
abstract::A 69-year-old woman presented with chronic lymphocytic leukemia (CLL) diagnosed after bone marrow recovery following intensive chemotherapy for acute lymphoblastic leukemia. The retrospective diagnosis of initial blastic transformation of CLL was made. The patient eventually died, 5 months after initial blastic phase,...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000205751
更新日期:1988-01-01 00:00:00
abstract::Agranulocytosis is a rare side effect of phenytoin treatment. We describe the case of an elderly man who developed agranulocytosis 2 weeks following initiation of phenytoin treatment, on no cytotoxic drugs or any other medications except decadron. The white blood cell count was 300/mm3 with absent granulocytes. The li...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000204838
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Immunotherapy using recombinant human interleukin-2 (rIL-2) produces objective responses in a proportion of advanced cancer patients. While early investigators employed intravenous (i.v.) treatment regimens, recent clinical trials applied therapy schedules via subcutaneous (s.c.) injection, mostly in combina...
journal_title:Acta haematologica
pub_type: 临床试验,杂志文章
doi:10.1159/000204503
更新日期:1993-01-01 00:00:00
abstract::Leukemic cells of a patient with acute T-lymphoblastic leukemia (T-ALL) exhibiting the uncommon clinical feature of hypogammaglobulinemia were examined in terms of surface markers and immunologic functions. Employing various monoclonal reagents reacting with surface antigens present on T cells and additional conventio...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000206496
更新日期:1984-01-01 00:00:00
abstract::Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) is a rare lymphoproliferative disorder characterized by diffuse lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, and polyclonal hypergammaglobulinemia. Morphologically, the involved lymph nodes demonstrate complete effacement of the normal arch...
journal_title:Acta haematologica
pub_type: 杂志文章,评审
doi:10.1159/000040811
更新日期:1998-01-01 00:00:00
abstract::Acute myeloid leukemia (AML) is a stem cell malignancy that originates in the bone marrow and involves the peripheral blood. Extramedullary AML is rarer, but it is most commonly associated with the former French-American-British (FAB) subtypes M4 or M5 of AML. AML cells may also home to the central nervous system and ...
journal_title:Acta haematologica
pub_type:
doi:10.1159/000508526
更新日期:2020-08-19 00:00:00
abstract::Non-Hodgkin's lymphomas are among the most challenging diseases to treat and their course ranges from very aggressive and rapidly fatal tumors to some of the most indolent, well-tolerated malignancies in man. ...
journal_title:Acta haematologica
pub_type: 杂志文章,评审
doi:10.1159/000205923
更新日期:1987-01-01 00:00:00
abstract::Recently, concerns have been raised regarding the potential impairment of neonatal platelet function and the potential risk of bleeding in neonates born to mothers treated with selective serotonin reuptake inhibitors (SSRI). Our aim was to test whether the platelet function of neonates born to SSRI-treated mothers was...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000090929
更新日期:2006-01-01 00:00:00
abstract::Hypercalcemia is a significant feature of patients with active multiple myeloma (MM) with extensive bone disease. Among the causes of non-neoplastic hypercalcemia, primary hyperparathyroidism (PHPT) is one of the most common, leading to osteoporosis and bone fractures. Interestingly, some preclinical data indicate tha...
journal_title:Acta haematologica
pub_type:
doi:10.1159/000509768
更新日期:2020-09-09 00:00:00
abstract::A patient with acute monoblastic leukemia developed a coagulopathy during chemotherapy. Coagulation studies showed thrombocytopenia, hypofibrinogenemia, high levels of fibrinogen degradation products, a negative protemine test but a normal antithrombin III level. These observations suggest that coagulation abnormaliti...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000207433
更新日期:1980-01-01 00:00:00
abstract:BACKGROUND:The relation with SNF5 mutation and chromosome 22 abnormalities is not clear in hematological neoplasms. METHODS:To elucidate the relevance of the SNF5 gene on 22q11.2, karyotypes were reviewed in 283 hematological neoplasms. Loss of heterozygosity (LOH) on 22q was analyzed in 21 plasma cell myelomas withou...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000324932
更新日期:2011-01-01 00:00:00
abstract:OBJECTIVE:To review the diagnostic significance, safety and possible risk factors of splenectomy in fever of unknown origin (FUO) with splenomegaly. METHODS:The records of 54 patients with FUO and splenomegaly who underwent splenectomy in our hospital in the past 20 years were reviewed retrospectively. Pathologic find...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000118632
更新日期:2008-01-01 00:00:00
abstract::A case of acute leukaemia with t(4;11) chromosomal abnormality in a 28-year-old woman is reported. At diagnosis, two blast cell populations were seen: 60% of the cells were small cells with lymphoid morphology, 40% were large cells with monocytic morphology. Cytochemical examination was consistent with acute myeloid l...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000206046
更新日期:1986-01-01 00:00:00
abstract::A hairy-cell leukaemia (HCL) cell line, HCL-O, was established from the peripheral blood of a 62-year-old Japanese patient with a unique variant of HCL strongly expressing CD21, the receptor for the Epstein-Barr virus (EBV). The HCL-O cells expressed antigens similar and dissimilar to those expressed with the original...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000204129
更新日期:1994-01-01 00:00:00
abstract::A new case of IgE myeloma is described. A 77-year-old woman presented with bone pain and fatigue. Serum protein analysis revealed a paraprotein of the IgE kappa type; bone marrow aspirate and immunofluorescence confirmed the diagnosis; ultrastructural examination showed immature plasma cells. Treatment with prednisone...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000204851
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Despite encouraging reports concerning the declining prevalence of iron deficiency, this easily preventable disorder is still an existing problem in presumably developed regions. OBJECTIVE:To evaluate the prevalence of iron deficiency and relevant anemia in children residing in Northern Greece and to study ...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000098273
更新日期:2007-01-01 00:00:00
abstract::Factor VIII (FVIII) inhibitor antibodies are produced against functional epitopes of FVIII in about 30% of severe hemophilia A patients leading to inhibition of its procoagulant activity. The Bethesda assay, the most commonly used method to measure FVIII inhibitors, based on inhibition of coagulant activity of FVIII, ...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000086580
更新日期:2005-01-01 00:00:00
abstract::We examined the in vivo effect of granulocyte colony-stimulating factor (G-CSF) on the surface expression of putative counterligands for endothelial selectins on neutrophils in healthy volunteers. G-CSF (50 microg/m2/day) was administered subcutaneously to 5 healthy volunteers for 4 days. The expression of surface ant...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000040901
更新日期:1998-01-01 00:00:00
abstract::In 34 patients with chronic lymphatic leukaemia (CLL) the lymphocytes have been separated and sized using a C1000 Channelyzer. The modal volume and the volume range of the populations have been obtained and related to clinical stage and mouse red blood cell (MRBC) rosetting capacity. Over 1 year's observation with sev...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000206714
更新日期:1983-01-01 00:00:00
abstract::Thymopoietin (TP) was originally isolated as a 5-kD 49-aa protein from bovine thymus and was subsequently observed to affect T-cell differentiation and function. We report here the molecular cloning of a murine TP cDNA. The 2,514 bp fragment contains a 630 bp open reading frame that encodes for 210 aa, highly homologo...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000203673
更新日期:1997-01-01 00:00:00
abstract::There have been many reports of patients with ampulla cardiomyopathy described as takotsubo-shaped cardiomyopathy in the cardiovascular field. This unique cardiomyopathy is characterized by transient apical ballooning and hypokinesis of the left ventricle. We describe 2 cases of ampulla cardiomyopathy associated with ...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000098461
更新日期:2007-01-01 00:00:00
abstract::A rare case of acute promyelcytic leukemia (APL) is reported in a 7-year-old boy. The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis. The bleeding diathesis in the case...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000207589
更新日期:1979-01-01 00:00:00
abstract::Hypercalcemia in malignancies is a frequent complication, mostly affecting patients with solid tumors or multiple myeloma. Calcium elevation is induced by direct bone infiltration of a tumor mass or through calcium liberation from the skeleton by a humoral mediator. The latter mechanism is referred to as humoral hyper...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000314646
更新日期:2010-01-01 00:00:00
abstract::Although multiple myeloma (MM) remains an incurable disease, its treatment has improved over the past decade. This improvement has been at least in part due to the introduction of novel antimyeloma agents with new mechanisms of action, including those that target both myeloma cells and the tumor microenvironment, with...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000094682
更新日期:2006-01-01 00:00:00
abstract::2-Chlorodeoxyadenosine (cladribine, Leustatin) is being used extensively in the treatment of hematologic malignancies, but relatively little is known regarding its toxicity to the normal marrow. Long-term serial hematologic observations have been made on 29 patients with multiple sclerosis undergoing experimental ther...
journal_title:Acta haematologica
pub_type: 临床试验,杂志文章
doi:10.1159/000204236
更新日期:1994-01-01 00:00:00
abstract::Two unrelated patients with Bernard-Soulier syndrome and their relatives were studied. The patients demonstrated severe bleeding diathesis, the relatives were asymptomatic. The propositi showed the characteristic abnormalities of the syndrome: thrombocytopenia, a percentage of giant platelets higher than 65%, prolonge...
journal_title:Acta haematologica
pub_type: 杂志文章
doi:10.1159/000206125
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVES:Reticulated platelets circulating in the blood reflect megakaryopoietic activity and platelet turnover and can be automatically and low-invasively measured as the immature platelet fraction (IPF) using a Sysmex XN hematocytometer. The present study retrospectively investigated whether or not the IPF can pred...
journal_title:Acta haematologica
pub_type: 新闻
doi:10.1159/000510460
更新日期:2020-09-17 00:00:00