Characterization of a diester lipase activity in human erythrocytes.

abstract：:Coagulation factor VIII inhibitor arising in a patient with autoimmune disease was immunologically analyzed. A 63-year-old man who had been diagnosed as suffering from polyarteritis nodosa was treated with prednisolone for 10 years. Severe bleeding tendency developed and coagulation studies demonstrated a high titer o...

journal_title：Acta haematologica

authors： Okamura T,Yamauchi Y,Fukuda T,Suehiro K,Murakawa M,Shibuya T,Nagasawa K,Harada M,Niho Y

更新日期：1991-01-01 00:00:00

abstract：:The maturation process of leukemic myelomonocytoid cells derived from peripheral blood of two typical cases of chronic myelomonocytic leukemia was investigated in vitro. In both cases, liquid culture of the leukemic cells in the presence or absence of 12-o-tetradecanoyl phorbol-13-acetate yielded either monocyte-macro...

journal_title：Acta haematologica

authors： Takuwa N,Kanegasaki S,Asano S,Tomita T,Nakayama E,Sato N,Shinohara T,Miwa S

更新日期：1984-01-01 00:00:00

abstract：:The frequency of chronic lymphocytic leukemia (CLL) varies a great deal from one population to another. We have undertaken to compare the aspects of CLL in Maghreb and Europe through two series of comparable importance, studied during the same period and under similar conditions in Algiers and Amiens. This comparison ...

journal_title：Acta haematologica

authors： Bellabes S,Hamman P,Desablens B,Colonna P,Messerschmitt J

更新日期：1983-01-01 00:00:00

abstract：:A 51-year-old male with acute lymphoblastic leukemia whose course was complicated by primary fibrinolysis and spontaneous rupture of the spleen is described. The patient was treated with various drug combinations: vincristine and prednisone, later by cytosine arabinoside and finally by prednisone, methotrexate and 6-m...

journal_title：Acta haematologica

authors： Gafter U,Mandel EM,Weiss S,Djaldetti M

更新日期：1976-01-01 00:00:00

abstract：:We describe a case of hemolytic anemia with subacute bacterial endocarditis due to Streptococcus sanguis. The major hematological features of the patient were a normocytic anemia with reticulocytosis, an elevation of serum lactate dehydrogenase, and a marked reduction of serum haptoglobin. All these signs of hemolytic...

journal_title：Acta haematologica

authors： Inada T,Shirono K,Tsuda H

更新日期：1995-01-01 00:00:00

abstract：:In evaluating hypoimmunoglobulinemia in a patient with nonsecretory myeloma, studies of in vitro immunoglobulin synthesis were performed during a 3-year period. Impaired polyclonal response to mitogen stimulation associated with excessive suppressor activity was demonstrable at diagnosis. Despite successful chemothera...

journal_title：Acta haematologica

authors： Shustik C,Michel R,Karsh J

更新日期：1988-01-01 00:00:00

abstract：:To evaluate the effect of granulocyte/colony-stimulating factor (G-CSF) on the onset of the adult respiratory distress syndrome (ARDS), we investigated whether the incidence of ARDS due to pulmonary infection differed between the G-CSF group which received chemotherapy with G-CSF and historical controls without G-CSF....

journal_title：Acta haematologica

authors： Takahashi Y,Kobayashi Y,Chikayama S,Ikeda M,Kondo M

更新日期：1999-01-01 00:00:00

abstract：:Drug-induced immune hemolytic anemia is a rare but underdiagnosed and potentially fatal condition. We report a case of severe hemolytic anemia induced by cefoxitin in a 45-year-old woman admitted with menometrorrhagia. Hemoglobin levels reached a nadir of 4.7 g/dl approximately 72 h after cefoxitin initiation, and hem...

journal_title：Acta haematologica

authors： Leaf DE,Langer NB,Markowski M,Garratty G,Diuguid DL

更新日期：2010-01-01 00:00:00

abstract：:A case of angioimmunoblastic lymphadenopathy (AILD) with important autoimmune symptoms disappearing under Levamisole therapy is reported. Since Levamisole is thought to have no direct effect on B cells, it is supposed that in AILD it regulates B lymphocyte activity via the restoration of impaired T cell functions. ...

journal_title：Acta haematologica

authors： Andrieu JM,Youinou P,Herzog C

更新日期：1979-01-01 00:00:00

abstract：:Primary lymphoma of the female genital tract is very rare. We report the case of a 36-year-old woman who was referred to our hospital because of an indeterminate Pap smear test. The colposcopy showed a thickening of the posterior vaginal wall and various irregular ulcerated nodular lesions. Histological examination, i...

journal_title：Acta haematologica

authors： Guastafierro S,Tedeschi A,Criscuolo C,Celentano M,Cobellis L,Rossiello R,Falcone U

更新日期：2012-01-01 00:00:00

abstract：:Scanning electron microscopy has shown a typical cell surface morphology in hairy cell leukemia. Scanning immunoelectron microscope techniques, utilizing monoclonal antibodies and colloidal gold particles, have recently become available. Eight patients with hairy cell leukemia have been studied with a panel of monoclo...

journal_title：Acta haematologica

authors： Soligo D,Lambertenghi-Deliliers G,Nava MT,Polli N,Cattoretti G,Polli EE

更新日期：1985-01-01 00:00:00

abstract：:Factor VII deficiency is the least rare among uncommon congenital coagulation disorders. The majority of cases are isolated deficiencies. In some cases, FVII deficiency has been found to be associated with the deficiency in another coagulation factor or with non-coagulation-related abnormalities or defects. The evalua...

journal_title：Acta haematologica

authors： Girolami A,Ruzzon E,Tezza F,Allemand E,Vettore S

更新日期：2007-01-01 00:00:00

abstract：:A case of acute leukaemia with t(4;11) chromosomal abnormality in a 28-year-old woman is reported. At diagnosis, two blast cell populations were seen: 60% of the cells were small cells with lymphoid morphology, 40% were large cells with monocytic morphology. Cytochemical examination was consistent with acute myeloid l...

journal_title：Acta haematologica

authors： Campos L,Espinouse D,Felman P,Charrin C,Gentilhomme O,Germain D

更新日期：1986-01-01 00:00:00

abstract：:Recombinant alpha-interferons are used as therapeutic agents in an increasing number of benign and malignant disorders. Long-term administration of recombinant alpha-interferon as a maintenance agent is associated with a small number of adverse side-effects which are responsible for patient intolerance of this drug. T...

journal_title：Acta haematologica

authors： Giles FJ,Worman CP,Jewell AP,Goldstone AH

更新日期：1991-01-01 00:00:00

abstract：:Platelet aggregation in diabetic retinopathy was investigated in a group of 25 patients. An enhanced activity induced by epinephrine and arachidonic acid was found in this group as compared with the controls, whereas in adenosine diphosphate (ADP) platelet aggregation no differences were observed. Spontaneous aggregat...

journal_title：Acta haematologica

authors： Creter D,Pavlotzky F,Savir H

更新日期：1978-01-01 00:00:00

abstract：:A 28-year-old woman with Bence-Jones multiple myeloma (MM) presented with several osteolytic lesions and a massive bone marrow infiltration with mature plasmocytes. After 6 cycles of chemotherapy with melphalan and prednisone, the patient, in apparent clinical remission, underwent allogeneic bone marrow transplantatio...

journal_title：Acta haematologica

authors： Gallamini A,Buffa F,Bacigalupo A,Van Lint MT,Peralvo J,Pittaluga PA,Occhini D,Marmont AM

更新日期：1987-01-01 00:00:00

abstract：:Contamination of autologous graft by tumor, in addition to incomplete tumor eradication, can partly explain why relapse remains the commonest cause of treatment failure after autologous stem cell transplantation (ASCT) in patients with malignant hematologic disorders. Monitoring of minimal residual disease (MRD) is no...

journal_title：Acta haematologica

authors： Melillo L,Cascavilla N,Lerma E,Corsetti MT,Carella AM

更新日期：2005-01-01 00:00:00

abstract：:We report a patient with myelodysplastic syndrome (MDS), refractory anaemia with excess blasts in transformation, in whom complete remission (CR) was achieved with the administration of granulocyte colony-stimulating factor (G-CSF). The 76-year-old patient was admitted to our hospital with a fever and a productive cou...

journal_title：Acta haematologica

authors： Kondo H,Kasahara Y,Mori A

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Argininemia is an autosomal recessive urea cycle disorder (UCD). Unlike other UCD, hyperammonemia is rarely seen. Patients usually present in childhood with neurological symptoms. Uncommon presentations like neonatal cholestasis or cirrhosis have been reported. Although transient elevations of liver transami...

journal_title：Acta haematologica

authors： Kiykim E,Zubarioglu T,Cansever MS,Celkan T,Häberle J,Aktuglu Zeybek AC

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVE:To investigate a family with factor VII (FVII) deficiency from Argentina. PATIENTS AND METHODS:The proposita is a 14-year-old girl who presented with a mild to moderate bleeding tendency. Menorrhagia is controlled with periodical administration of small doses of recombinant FVII concentrate. The mother of th...

journal_title：Acta haematologica

authors： Girolami A,Paoletti M,Ferrari S,Garcia D

更新日期：2021-01-01 00:00:00

abstract：:34 patients with myocardial infarction were studied with daily measurements of beta-thromboglobulin (BTG) and 125I fibrinogen scanning in order to detect deep-venous thrombosis (DVT). Serial levels of BTG were unhelpful in the early detection of this condition, which occurred in 7 of the patients studied. 5 of the pat...

journal_title：Acta haematologica

authors： Simmonds JP,O'Malley BP,Maskill MR,O'Connor JF,Burridge DJ

更新日期：1980-01-01 00:00:00

abstract：:We describe a patient with hemophagocytic syndrome resembling malignant histiocytosis which was complicating myelodysplastic disease of 3 years duration. Detailed morphological and ultrastructural studies indicate that the histiocytic component did not demonstrate features of malignancy. A review of other known malign...

journal_title：Acta haematologica

authors： Prokocimer M,Inbal A,Gelber M,Shohat B,Ben Basat M,Shaklai M

更新日期：1985-01-01 00:00:00

abstract：:A new case of IgE myeloma is described. A 77-year-old woman presented with bone pain and fatigue. Serum protein analysis revealed a paraprotein of the IgE kappa type; bone marrow aspirate and immunofluorescence confirmed the diagnosis; ultrastructural examination showed immature plasma cells. Treatment with prednisone...

journal_title：Acta haematologica

authors： Invernizzi F,Monti G,Caviglia AG,Meroni P,Zanussi C

更新日期：1991-01-01 00:00:00

abstract：:In most patients with large granular lymphocyte (LGL) leukemia, the disease appears to progress slowly if at all, and no therapy is generally required. We present a patient with CD3+ CD8+ CD16+ LGL leukemia, who showed a benign clinical course for more than 7 months without therapy, but subsequently developed aggressi...

journal_title：Acta haematologica

authors： Matsubara A,Matsumoto M,Takada K,Hato T,Hasegawa H,Tamai T,Yasukawa M,Fujita S

更新日期：1994-01-01 00:00:00

abstract：:The activity of gamma-glutamyl transpeptidase was investigated in normal and leukemia leukocytes. Enzyme activity was positively correlated with the proportion of mature neutrophils and monocytes. In isolated leukocytes from patients with acute myeloid leukemia low values were obtained compared to controls. ...

journal_title：Acta haematologica

authors： Hultberg B,Sjögren U

更新日期：1980-01-01 00:00:00

abstract：:In 33 children with cyanotic congenital heart disease the platelet function has been studied. The most significant changes were reduced platelet adhesiveness to glass and impaired availability of platelet factor 3 in nearly 50% of the patients. Although clot retraction was poor in 84% of them, thrombocytopenia and pro...

journal_title：Acta haematologica

authors： Bhargava M,Sanyal SK,Thapar MK,Kumar S,Hooja V

更新日期：1976-01-01 00:00:00

abstract：:A rare case of acute promyelcytic leukemia (APL) is reported in a 7-year-old boy. The patient displayed the typical features of APL including impaction of the marrow with promyelocytes, marked elevation of the serum vitamin B12 and transcobalamin I levels and a hemorrhagic diathesis. The bleeding diathesis in the case...

journal_title：Acta haematologica

authors： Engelhard D,Yatziv S,Rachmilewitz EA,Polliack A

更新日期：1979-01-01 00:00:00

abstract：:Monosomy 7 myelodysplasia is a rare hematological entity and is associated with morphological abnormalities in bone marrow and peripheral smear, and poor prognosis in children. We describe 2 children with infantile monosomy 7 myelodysplasia which evolved to leukemia. One of them died after 1 month, and the other is st...

journal_title：Acta haematologica

authors： Yeşilipek MA,Lüleci G,Velipaşaoğlu S,Berker S,Yeğin O

更新日期：1994-01-01 00:00:00

abstract：:The transcription factors GATA-1 and GATA-2 play key roles in gene regulation during erythropoiesis. Gene ablation studies in mouse revealed that GATA-2 is crucial for the maintenance and proliferation of immature hematopoietic progenitors, whereas GATA-1 is essential for the survival of erythroid progenitors as well ...

journal_title：Acta haematologica

authors： Ohneda K,Yamamoto M

更新日期：2002-01-01 00:00:00

abstract：:In the myelodysplastic syndromes (MDS) clonogenic marrow cell culture studies have demonstrated intrinsic hemopoietic stem cell and progenitor cell abnormalities consistent with these disorders representing clonal hemopathies. Abnormal responsiveness of these cells to stimulatory and inhibitory growth factors indicate...

journal_title：Acta haematologica

authors： Greenberg PL

更新日期：1987-01-01 00:00:00