Current status of antioxidant therapy for Alzheimer's Disease.

abstract：CONTEXT:Racial differences in receipt of cancer prevention services may be related to poorer outcomes for minorities. Understanding reasons for such differences could help target appropriate interventions. OBJECTIVES:To determine if racial differences exist in the use of cancer prevention services among older blacks a...

journal_title：Journal of the American Geriatrics Society

authors： Hegarty V,Burchett BM,Gold DT,Cohen HJ

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:To investigate the cause of worse survival in older patients after myocardial infarction (MI). DESIGN:Prospective 18-month and longer follow-up study of a cohort of 167 patients (mean age +/- standard deviation 58 +/- 12, including 71 aged >or=65) with acute MI for cardiac events, defined as cardiac death, ...

journal_title：Journal of the American Geriatrics Society

authors： Smart S,Sagar K,Tresch D

更新日期：2002-07-01 00:00:00

abstract：:The elderly take more drugs than the young, and are therefore more susceptible to adverse drug interactions. Prescribing the minimum number of agents is recommended. Drug absorption, metabolism, and excretion may be altered by various interactions. Dose-response relationships of oral anticoagulants, oral hypoglycemics...

journal_title：Journal of the American Geriatrics Society

authors： Reidenberg MM

更新日期：1982-11-01 00:00:00

abstract：OBJECTIVES:To assess mobility disability trajectories before death in a large sample of very old adults using two analytical approaches to determine how well they corresponded. DESIGN:Decedent sample from the Health, Aging and Body Composition (Health ABC) Study. Data were collected between 1997 and 2015. SETTING:Pit...

journal_title：Journal of the American Geriatrics Society

authors： Lunney JR,Albert SM,Boudreau R,Ives D,Satterfield S,Newman AB,Harris T,Health Aging and Body Composition Study.

更新日期：2018-03-01 00:00:00

abstract：:The Integrated Memory Care Clinic (IMCC) is a patient-centered medical home as defined by the National Committee for Quality Assurance directed by advanced practice registered nurses (APRNs) caring for persons living with dementia (PLWD); physicians provide specialty consultation but do not direct care or care plannin...

journal_title：Journal of the American Geriatrics Society

authors： Clevenger CK,Cellar J,Kovaleva M,Medders L,Hepburn K

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:We examined predictors of hospital and 6-month mortality in older Medical Intensive Care Unit (MICU) patients with particular attention to age and functional status. Age is generally thought to be strongly associated with intensive care outcomes, but this relationship may be confounded by age-related changes....

journal_title：Journal of the American Geriatrics Society

authors： Mayer-Oakes SA,Oye RK,Leake B

更新日期：1991-09-01 00:00:00

abstract：OBJECTIVES:To evaluate whether levels of cognitive reserve (CR), as measured using the Wechsler Adult Intelligence Scale (WAIS)-III vocabulary test, moderated longitudinal associations between cognitive functions and decline in gait speed in a community-based cohort of older adults without dementia, specifically, wheth...

journal_title：Journal of the American Geriatrics Society

authors： Holtzer R,Wang C,Lipton R,Verghese J

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:To develop and validate the Time and Change (T&C) test, a simple, standardized method for detecting dementia in a diverse older outpatient population with varying levels of education. DESIGN:A prospective cohort validation study. SETTING:Two outpatient clinics at an urban teaching hospital. PARTICIPANTS:Th...

journal_title：Journal of the American Geriatrics Society

authors： Froehlich TE,Robison JT,Inouye SK

更新日期：1998-12-01 00:00:00

abstract：OBJECTIVES:To determine whether serum calcium is associated with cognitive function in elderly individuals in the general population. DESIGN:Prospective follow-up study of two independent, population-based cohorts. SETTING:The Rotterdam Study (median follow-up 11 years) and the Leiden 85-plus Study (median follow-up ...

journal_title：Journal of the American Geriatrics Society

authors： Schram MT,Trompet S,Kamper AM,de Craen AJ,Hofman A,Euser SM,Breteler MM,Westendorp RG

更新日期：2007-11-01 00:00:00

abstract：:Osteoporosis and sarcopenia are degenerative diseases frequently associated with aging. The loss of bone and muscle results in significant morbidity, so preventing or attenuating osteoporosis and sarcopenia is an important public health goal. Dietary protein is crucial for development of bone and muscle, and recent ev...

journal_title：Journal of the American Geriatrics Society

authors： Gaffney-Stomberg E,Insogna KL,Rodriguez NR,Kerstetter JE

更新日期：2009-06-01 00:00:00

abstract：OBJECTIVES:To provide descriptive epidemiological information on identified depression in nursing home residents. DESIGN:Survey of the 1996 Medical Expenditure Panel Survey-Nursing Home Component (MEPS-NHC). SETTING:Nine hundred fifty-one nursing facilities. PARTICIPANTS:Three thousand seven hundred ten noncomatose ...

journal_title：Journal of the American Geriatrics Society

authors： Jones RN,Marcantonio ER,Rabinowitz T

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:To examine the associations between amyloid-β brain deposition and physical activity (PA) in elderly adults without dementia and to investigate whether the association has a dose-response relationship. DESIGN:Cross-sectional study. SETTING:French community-dwelling people. PARTICIPANTS:Elderly adults with...

journal_title：Journal of the American Geriatrics Society

authors： de Souto Barreto P,Andrieu S,Payoux P,Demougeot L,Rolland Y,Vellas B,Multidomain Alzheimer Preventive Trial\/Data Sharing Alzheimer Study Group.

更新日期：2015-08-01 00:00:00

abstract：:The contribution of frailty to human morbidity and mortality is immense. Yet it lacks a conceptual framework. By borrowing from the hypotheses provided by the thermophysicists, frailty can be understood in a way that both interrelates the relationship between form and function and provides medical science with an oper...

journal_title：Journal of the American Geriatrics Society

authors： Bortz WM 2nd

更新日期：1993-09-01 00:00:00

abstract：:Pretreatment with a somatostatin analogue, octreotide (SMS 201-995), prevents postprandial blood pressure reduction in the elderly. We hypothesized that this beneficial effect on blood pressure is caused by an octreotide-induced suppression of insulin secretion. We studied the effects of octreotide and insulin adminis...

journal_title：Journal of the American Geriatrics Society

authors： Jansen RW,de Meijer PH,van Lier HJ,Hoefnagels WH

更新日期：1989-12-01 00:00:00

abstract：:The introduction of Japan's long-term care insurance (LTCI) system in April 2000 has made long-term care an explicit and universal entitlement for every Japanese person aged 65 and older based strictly on physical and mental status. At the start of the program, more than two million seniors were expected to apply for ...

journal_title：Journal of the American Geriatrics Society

authors： Tsutsui T,Muramatsu N

更新日期：2005-03-01 00:00:00

abstract：:Catechol-O-methyltransferase (COMT) inhibitors are a new therapeutic option in the treatment of patients with Parkinson's disease. COMT inhibitors act by extending the duration of action of levodopa, thus improving the amount of time a patient can experience benefit from levodopa. COMT inhibitors are only used in conj...

journal_title：Journal of the American Geriatrics Society

authors： Waters C

更新日期：2000-06-01 00:00:00

abstract：:Demographic information suggests that the problems of alcohol abuse among the elderly will increase at least in proportion to the population growth of that sector. While fewer older people drink and average consumption declines, four factors that promote alcohol abuse are noted. These are: 1) retirement, with its atte...

journal_title：Journal of the American Geriatrics Society

authors： Brody JA

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVES:Family caregiving is an integral part of the care system for persons with dementing disorders, such as Alzheimer's disease. This study tested role-training intervention as a way to help family caregivers appreciate and assume a more clinical belief set about caregiving and thereby ameliorate the adverse outc...

journal_title：Journal of the American Geriatrics Society

authors： Hepburn KW,Tornatore J,Center B,Ostwald SW

更新日期：2001-04-01 00:00:00

abstract：OBJECTIVES:To study whether there are any negative or positive effects of 6 months of increased fluid intake in reasonably healthy elderly men. DESIGN:Randomized trial. SETTING:Community-based. PARTICIPANTS:One hundred forty-one healthy participants aged 55 to 75. INTERVENTION:One group was given the advice to incr...

journal_title：Journal of the American Geriatrics Society

authors： Spigt MG,Knottnerus JA,Westerterp KR,Olde Rikkert MG,Schayck CP

更新日期：2006-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to examine physical activity and the predictors of physical activity and exercise among nursing home residents. DESIGN:Population study. PARTICIPANTS:The sample (n = 190) was obtained by selecting every man and every second women from the entire nursing home population (n = 346...

journal_title：Journal of the American Geriatrics Society

authors： Ruuskanen JM,Parkatti T

更新日期：1994-09-01 00:00:00

abstract：:The ratio of pepsinogen I to pepsinogen II in the circulation decreases progressively with increasing severity of atrophic gastritis of the fundic gland mucosa. Fasting blood was obtained from 359 free-living and institutionalized elderly people (age range, 60 to 99 years). A pepsinogen I/pepsinogen II ratio less than...

journal_title：Journal of the American Geriatrics Society

authors： Krasinski SD,Russell RM,Samloff IM,Jacob RA,Dallal GE,McGandy RB,Hartz SC

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence and predictors of adverse postoperative outcomes in older surgical patients undergoing noncardiac surgery. DESIGN:Prospective cohort study of consecutive patients undergoing noncardiac surgery in 1997. SETTING:A medical school-affiliated teaching community hospital. PARTICIPANT...

journal_title：Journal of the American Geriatrics Society

authors： Leung JM,Dzankic S

更新日期：2001-08-01 00:00:00

abstract：:Falls are a serious, persistent problem in hospitals. Ensuring that all hospital staff have adequate knowledge of how to prevent falls is the first step in prevention. We identified validated fall prevention knowledge tests (FPKTs) and planned to conduct a systematic literature review. When the review identified a lac...

journal_title：Journal of the American Geriatrics Society

authors： Dykes PC,Bogaisky M,Carter EJ,Duckworth M,Hurley AC,Jackson EM,Khasnabish S,Lindros ME,Lipsitz SR,Scanlan M,Yu SP,Bates DW,Adelman JS

更新日期：2019-01-01 00:00:00

abstract：:Contemporary, systematic approaches to injury prevention are presented as guides for considering needless death and disability of older people because of falls, burns, and vehicular crashes. Injury results from an unfavorable relationship between etiologic agent and host within a particular environment setting. Abnorm...

journal_title：Journal of the American Geriatrics Society

authors： Hogue CC

更新日期：1982-04-01 00:00:00

abstract：OBJECTIVE:To determine factors that predict change in walking velocity in older people using a multivariate model. DESIGN:Longitudinal observational study. SUBJECTS:A total of 588 persons older than age 60, including subjects residing in a continuing care retirement community (CCRC) (n = 248), and homebound (n = 79) ...

journal_title：Journal of the American Geriatrics Society

authors： Gibbs J,Hughes S,Dunlop D,Singer R,Chang RW

更新日期：1996-02-01 00:00:00

abstract：OBJECTIVES:To design a value-driven, interprofessional inpatient geriatric consultation program coordinated with systems-level changes and studied outcomes and costs. DESIGN:Propensity-matched case-control study of older adults hospitalized at an academic medical center (AMC) who did or did not receive geriatric consu...

journal_title：Journal of the American Geriatrics Society

authors： Bernstein JM,Graven P,Drago K,Dobbertin K,Eckstrom E

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVES:To determine whether an in-home palliative care intervention for terminally ill patients can improve patient satisfaction, reduce medical care costs, and increase the proportion of patients dying at home. DESIGN:A randomized, controlled trial. SETTING:Two health maintenance organizations in two states. PA...

journal_title：Journal of the American Geriatrics Society

authors： Brumley R,Enguidanos S,Jamison P,Seitz R,Morgenstern N,Saito S,McIlwane J,Hillary K,Gonzalez J

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVES:To assess 1-week prevalence of International Classification of Disease, Tenth Edition (ICD-10) current depression, physical comorbidity, associated disability, and healthcare utilization in older primary care patients. Comparisons with younger patients are also reported. DESIGN:Cross-sectional, two-phase ep...

journal_title：Journal of the American Geriatrics Society

authors： Berardi D,Menchetti M,De Ronchi D,Rucci P,Leggieri G,Ferrari G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults. DESIGN:Double-blind, randomized, controlled clinical trial. SETTING:Clinical research facility. PARTICIPANTS:One hundred ten men and 115 women aged 55 to 85 (mean +/- ...

journal_title：Journal of the American Geriatrics Society

authors： Kritz-Silverstein D,von Mühlen D,Laughlin GA,Bettencourt R

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:To estimate outcomes according to attained blood pressure (BP) in the oldest adults treated for hypertension in routine family practice. DESIGN:Cohort analysis of primary care inpatient and death certificate data for individuals with hypertension. SETTING:Primary care practices in England (Clinical Practic...

journal_title：Journal of the American Geriatrics Society

authors： Delgado J,Masoli JAH,Bowman K,Strain WD,Kuchel GA,Walters K,Lafortune L,Brayne C,Melzer D,Ble A,As part of the Ageing Well Programme of the NIHR School for Public Health Research, England.

更新日期：2017-05-01 00:00:00