The effects of 6 months of increased water intake on blood sodium, glomerular filtration rate, blood pressure, and quality of life in elderly (aged 55-75) men.

Abstract:

OBJECTIVES:To study whether there are any negative or positive effects of 6 months of increased fluid intake in reasonably healthy elderly men. DESIGN:Randomized trial. SETTING:Community-based. PARTICIPANTS:One hundred forty-one healthy participants aged 55 to 75. INTERVENTION:One group was given the advice to increase their daily fluid intake by 1.5 L of water; the other group was given placebo medication (8 mL inactive syrup per day). MEASUREMENTS:At 6 months blood sodium, glomerular filtration rate (GFR), blood pressure, and quality of life (QOL) were measured. The changes in water turnover were measured using deuterium. RESULTS:Most subjects did not manage to increase their fluid intake by 1.5 L. The average increase in the intervention group was approximately 1 L. Twenty-four-hour water turnover in the water group was 359 mL (95% confidence interval=171-548) higher than that of the control group at 6-month follow-up. Blood pressure, sodium level, GFR, and QOL did not change significantly in either group during the intervention period. In addition, the cases reporting a worsening on the effect measures were equally distributed over the two study groups. CONCLUSION:The advice to increase fluid intake by 1.5 L had no negative effects in reasonably healthy men aged 55 to 75.

journal_name

J Am Geriatr Soc

authors

Spigt MG,Knottnerus JA,Westerterp KR,Olde Rikkert MG,Schayck CP

doi

10.1111/j.1532-5415.2005.00606.x

subject

Has Abstract

pub_date

2006-03-01 00:00:00

pages

438-43

issue

3

eissn

0002-8614

issn

1532-5415

pii

JGS606

journal_volume

54

pub_type

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