The physics of frailty.

Abstract:

:The contribution of frailty to human morbidity and mortality is immense. Yet it lacks a conceptual framework. By borrowing from the hypotheses provided by the thermophysicists, frailty can be understood in a way that both interrelates the relationship between form and function and provides medical science with an operational insight that yields clinical benefit. Frailty results where the organism is uncoupled from its environment yielding a break in the forward feedback cycle of stimulus to reaction to growth to increased functional competence to improved response to stimulus. Recognition of the centrality of this interrelatedness to health becomes a key theme for illness prevention and therapy.

journal_name

J Am Geriatr Soc

authors

Bortz WM 2nd

subject

Has Abstract

pub_date

1993-09-01 00:00:00

pages

1004-8

issue

9

eissn

0002-8614

issn

1532-5415

journal_volume

41

pub_type

杂志文章,评审
  • Management and outcome of acute myocardial infarction in older patients in the thrombolytic era.

    abstract:OBJECTIVE:Acute myocardial infarction (AMI) is an important cause of mortality and morbidity in older patients. The aim of this study was to determine the proportion of unselected admissions with AMI that is older than 75 years and to examine management and outcomes in this group. DESIGN:An historical cohort study of ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1999.tb02991.x

    authors: Mahon NG,Codd MB,O'Rorke C,Egan B,McCann HA,Sugrue DD

    更新日期:1999-03-01 00:00:00

  • Memory complaint in a community sample aged 70 and older.

    abstract:OBJECTIVES:The ability of older people to estimate their own memory, often referred to as "metamemory," has been evaluated in previous studies with conflicting reports regarding accuracy. Some studies have suggested that an older person's metamemory is mostly accurate, whereas others have demonstrated little relationsh...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2000.tb02634.x

    authors: Turvey CL,Schultz S,Arndt S,Wallace RB,Herzog R

    更新日期:2000-11-01 00:00:00

  • Delirium: masquerades and misdiagnosis in elderly inpatients.

    abstract::Delirium is an organic mental disorder defined as transient, fluctuating global dysfunction of cognition. It is common in elderly medical inpatients, yet its varied presentation is often missed or misdiagnosed. ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1990.tb01505.x

    authors: Lyness JM

    更新日期:1990-11-01 00:00:00

  • The risk factors of age and family history and their relationship to screening mammography utilization.

    abstract:OBJECTIVE:To study the association of two well known risk factors for breast cancer and the association of knowledge of those risk factors with mammography utilization. DESIGN:Cross sectional: two independent random telephone surveys. SETTING:Two Northeastern metropolitan communities surveyed in 1987 and in 1989. PA...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1992.tb01848.x

    authors: Costanza ME,Stoddard A,Gaw VP,Zapka JG

    更新日期:1992-08-01 00:00:00

  • Community-acquired pneumonia in patients receiving home care.

    abstract:OBJECTIVES:To describe the features of community-acquired pneumonia (CAP) requiring hospitalization in subjects receiving home care. DESIGN:Prospective study from November 15, 2000, to November 14, 2002. SETTING:Six hospitals in the Edmonton, Canada, area. PARTICIPANTS:Two thousand four hundred sixty-four subjects a...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2005.53264.x

    authors: Marrie TJ,Huang JQ

    更新日期:2005-05-01 00:00:00

  • National Prescribing Trends for High-Risk Anticholinergic Medications in Older Adults.

    abstract:OBJECTIVES:To estimate prescribing tends of and correlates independently associated with high-risk anticholinergic prescriptions in adults aged 65 and older in office-based outpatient visits. DESIGN:Repeated cross-sectional analysis. SETTING:National Ambulatory Medical Care Survey (NAMCS). PARTICIPANTS:A national sa...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15357

    authors: Rhee TG,Choi YC,Ouellet GM,Ross JS

    更新日期:2018-07-01 00:00:00

  • The effect of volume expansion on atrial natriuretic peptide and cyclic guanosine monophosphate levels in young and aged subjects.

    abstract::The relationship between atrial natriuretic peptide (ANP) and age was studied. In elderly subjects (65 to 84 years) higher basal ANP levels were found as compared with those found in young subjects (21 to 23 years). Volume loading (750 mL 0.9% NaCl in 60 minutes) increased ANP levels only in the aged group, and plasma...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1990.tb01502.x

    authors: Tan AC,Hoefnagels WH,Swinkels LM,Kloppenborg PW,Benraad TJ

    更新日期:1990-11-01 00:00:00

  • Screening for Suicidal Thoughts and Behaviors in Older Adults in the Emergency Department.

    abstract:OBJECTIVES:To estimate the prevalence of self-harm, suicidal ideation (SI), and suicide attempts (SA) in older adults in the emergency department (ED), including differences according to age, sex, and race and ethnicity. DESIGN:Quasi-experimental, multiphase, eight-center study with prospective review of consecutive c...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,多中心研究

    doi:10.1111/jgs.14529

    authors: Betz ME,Arias SA,Segal DL,Miller I,Camargo CA Jr,Boudreaux ED

    更新日期:2016-10-01 00:00:00

  • A randomized trial of a combined physical activity and environmental intervention in nursing home residents: do sleep and agitation improve?

    abstract:OBJECTIVES:The purpose of this study was to test whether an intervention combining increased daytime physical activity with improvement in the nighttime environment improves sleep and decreases agitation in nursing home residents. DESIGN:A randomized trial. SETTING:One community nursing home in the Los Angeles, Calif...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.1999.tb03833.x

    authors: Alessi CA,Yoon EJ,Schnelle JF,Al-Samarrai NR,Cruise PA

    更新日期:1999-07-01 00:00:00

  • Aging and the prevalence of cardiovascular disease risk factors in older American Indians: the Strong Heart Study.

    abstract:OBJECTIVES:To describe longitudinal changes in the prevalence of major cardiovascular disease (CVD) risk factors in aging American Indians. DESIGN:Population-based ongoing epidemiological study. SETTING:The Strong Heart Study is a study of CVD and its risk factors. Standardized examinations were repeated in 1993 to 1...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2006.01018.x

    authors: Rhoades DA,Welty TK,Wang W,Yeh F,Devereux RB,Fabsitz RR,Lee ET,Howard BV

    更新日期:2007-01-01 00:00:00

  • Relationship between higher estradiol levels and 9-year mortality in older women: the Invecchiare in Chianti study.

    abstract:OBJECTIVES:To investigate the relationship between total estradiol (E2) levels and 9-year mortality in older postmenopausal women not taking hormone replacement therapy (HRT). DESIGN:Population-based study of persons living in the Chianti geographic area (Tuscany, Italy). SETTING:Community. PARTICIPANTS:A representa...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2009.02464.x

    authors: Maggio M,Ceda GP,Lauretani F,Bandinelli S,Ruggiero C,Guralnik JM,Metter EJ,Ling SM,Paolisso G,Valenti G,Cappola AR,Ferrucci L

    更新日期:2009-10-01 00:00:00

  • Freedom, dependency, and the care of the very old.

    abstract::Difficulties exist in making treatment decisions for the very old and dependent patient. In the years to come, these difficulties will increase. It is argued that such persons should not be abandoned to their "rights" as autonomous persons; yet quality of life judgments should also be avoided except in limited circums...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1984.tb00892.x

    authors: Thomasma DC

    更新日期:1984-12-01 00:00:00

  • Can a short period of micronutrient supplementation in older institutionalized people improve response to influenza vaccine? A randomized, controlled trial.

    abstract:OBJECTIVES:To test the hypothesis that a micronutrient supplement can improve seroconversion after influenza immunization in older institutionalized people. DESIGN:: Randomized, double-blind, placebo-controlled study. SETTING:Nursing and residential homes in Liverpool, United Kingdom. PARTICIPANTS:One hundred sixty-...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.2004.52005.x

    authors: Allsup SJ,Shenkin A,Gosney MA,Taylor S,Taylor W,Hammond M,Zambon MC

    更新日期:2004-01-01 00:00:00

  • Mobility device use in older adults and incidence of falls and worry about falling: findings from the 2011-2012 national health and aging trends study.

    abstract:OBJECTIVES:To examine the prevalence of mobility device use in community-dwelling older adults in the United States and to investigate the incidence of falls and worry about falling according to type and number of mobility devices used. DESIGN:Analysis of cross-sectional and longitudinal data from the 2011-12 National...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.13393

    authors: Gell NM,Wallace RB,LaCroix AZ,Mroz TM,Patel KV

    更新日期:2015-05-01 00:00:00

  • A life course model of cognitive activities, socioeconomic status, education, reading ability, and cognition.

    abstract:OBJECTIVES:To cross-sectionally quantify the contribution of proxy measures of cognitive reserve reflective of the lifespan, such as education, socioeconomic status (SES), reading ability, and cognitive activities, in explaining late-life cognition. DESIGN:Prospective observational cohort study of aging. SETTING:Reti...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2011.03499.x

    authors: Jefferson AL,Gibbons LE,Rentz DM,Carvalho JO,Manly J,Bennett DA,Jones RN

    更新日期:2011-08-01 00:00:00

  • Leveraging Home-Delivered Meal Programs to Address Unmet Needs for At-Risk Older Adults: Preliminary Data.

    abstract:BACKGROUND:Home-delivered meal programs serve a predominantly homebound older adult population, characterized by multiple chronic conditions, functional limitations, and a variety of complex care needs, both medical and social. DESIGN:A pilot study was designed to test the feasibility of leveraging routine meal-delive...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.16013

    authors: Morris AM,Engelberg JK,Schmitthenner B,Dosa D,Gadbois E,Shield RR,Akobundu U,Thomas KS

    更新日期:2019-09-01 00:00:00

  • When home care ends--changes in the physical health of informal caregivers caring for dementia patients: a longitudinal study.

    abstract:OBJECTIVES:To verify the change in health variables and parameters of health service utilization in a group of active caregivers for older persons with dementia in comparison with former caregivers who had ceased to provide home care for at least 6 months (death of the patient or institutionalized care). DESIGN:A pros...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1046/j.1532-5415.2002.50209.x

    authors: Gräsel E

    更新日期:2002-05-01 00:00:00

  • Urge incontinence: new health-related quality of life measures.

    abstract:OBJECTIVES:To develop and evaluate the psychometric properties of two new urge incontinence-specific instruments that measure quality of life and symptom annoyance. DESIGN:New instruments were developed and validated in racially, ethnically, and age-diverse community-dwelling women with urge or mixed incontinence with...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1999.tb01294.x

    authors: Brown JS,Posner SF,Stewart AL

    更新日期:1999-08-01 00:00:00

  • Reviews of individual patient data (IPD) are useful for geriatrics: an overview of available IPD reviews.

    abstract:OBJECTIVES:To determine how many individual patient data (IPD) reviews that included older people were available in MEDLINE and whether the effectiveness of treatments differed between older and younger individuals. DESIGN:Overview of IPD reviews. SETTING:A MEDLINE search was conducted for IPD reviews of randomized c...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,评审

    doi:10.1111/jgs.12830

    authors: van de Glind EM,Rhodius-Meester HF,Reitsma JB,Hooft L,van Munster BC

    更新日期:2014-06-01 00:00:00

  • A concept of loneliness in the elderly.

    abstract::The author's concept of loneliness is described, especially as it concerns the elderly. An attempt is made to develop an understanding of the word, with its implications for guidance in the nursing profession. The nurse's defenses against her own feelings of loneliness and depression can inhibit therapeutic interactio...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.1978.tb05048.x

    authors: Williams LM

    更新日期:1978-04-01 00:00:00

  • The Competing Risk of Death in Longitudinal Geriatric Outcomes.

    abstract:OBJECTIVES:To address the competing risk of death in longitudinal studies of older persons, we demonstrate sensitivity analyses that evaluate robustness of associations between exposures and three outcome types: dichotomous, count, and time to event. DESIGN:A secondary analysis of data from a prospective cohort study....

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15697

    authors: Murphy TE,Gill TM,Leo-Summers LS,Gahbauer EA,Pisani MA,Ferrante LE

    更新日期:2019-02-01 00:00:00

  • Correlation Between Use of Zopiclone and Risk of Hip Fracture in Elderly Adults: A Case-Control Study in Taiwan.

    abstract:OBJECTIVES:To investigate the correlation between zopiclone use and risk of hip fracture in elderly adults. DESIGN:Case-control study. SETTING:Claim data from the Taiwan National Health Insurance Program. PARTICIPANTS:Individuals aged 65 and older who experienced their first episode of hip fracture between 1998 and ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.13823

    authors: Lai SW,Lin CL,Chen WC,Liao KF

    更新日期:2015-12-01 00:00:00

  • The effect of medicated chewing gums on oral health in frail older people: a 1-year clinical trial.

    abstract:OBJECTIVES:To determine the effects of a medicated chewing gum on the oral health of frail older people. DESIGN:A controlled, double-blind trial using three groups based on random allocation of residential homes. SETTING:Sixteen residential homes in West Hertfordshire, England. PARTICIPANTS:One hundred eleven dentat...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1046/j.1532-5415.2002.50355.x

    authors: Simons D,Brailsford SR,Kidd EA,Beighton D

    更新日期:2002-08-01 00:00:00

  • Confusion Strongly Associated with Antibiotic Prescribing Due to Suspected Urinary Tract Infections in Nursing Homes.

    abstract:OBJECTIVES:To quantify the prevalence of documented urinary tract infection (UTI), nonspecific symptoms, and antibiotic treatment of suspected UTI in nursing homes (NHs) in the tropics and to describe the typical resident likely to receive antibiotic treatment for suspected UTI and factors associated with the developme...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15179

    authors: Mayne S,Sundvall PD,Gunnarsson R

    更新日期:2018-02-01 00:00:00

  • Replacement of Urinary Catheter for Urinary Tract Infections: A Prospective Observational Study.

    abstract:OBJECTIVES:To assess whether catheter replacement is associated with better clinical outcomes in individuals with long-term urinary catheters. DESIGN:Prospective, noninterventional study. PARTICIPANTS:Individuals (mean age 79.2±11.5) who had had an indwelling urinary catheter for longer than 7 days and a symptomatic ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15517

    authors: Babich T,Zusman O,Elbaz M,Ben-Zvi H,Paul M,Leibovici L,Avni T

    更新日期:2018-09-01 00:00:00

  • Do-Not-Hospitalize Orders in Nursing Homes: "Call the Family Instead of Calling the Ambulance".

    abstract:OBJECTIVES:To determine how do-not-hospitalize (DNH) orders are interpreted and used in nursing homes (NHs) once they are in place. DESIGN:Qualitative study using in-depth semi-structured interviews performed from December 2013 to April 2014. SETTING:Eight skilled nursing facilities in Connecticut that ranked in the ...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.14879

    authors: Cohen AB,Knobf MT,Fried TR

    更新日期:2017-07-01 00:00:00

  • Issues in clinical trials with the depressed elderly.

    abstract::Despite the fact that there is a high prevalence of depression among the elderly, little research on the efficacy of psychotherapy or pharmacotherapy with the elderly has been reported in the literature. This paper describes a sample of 18 elderly patients who received both psychotherapy and pharmacotherapy for the tr...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1111/j.1532-5415.1982.tb01982.x

    authors: Rothblum ED,Sholomskas AJ,Berry C,Prusoff BA

    更新日期:1982-11-01 00:00:00

  • Aging in the United Kingdom and Europe--a snapshot of the future?

    abstract::The implications for society of increasing life span to 120 years can only be guessed, but comparing the diversity of responses to aging in different countries may give insights into the possible effect. A European Union-funded study of the recipients of community care services in 11 European countries illustrates how...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/j.1532-5415.2005.53497.x

    authors: Carpenter GI

    更新日期:2005-09-01 00:00:00

  • Testing the effect of function-focused care in assisted living.

    abstract:OBJECTIVES:To develop and test the Function-Focused Care in Assisted Living (FFC-AL) intervention so as to alter the decline that older adults in AL experience. DESIGN:Cluster-randomized controlled trial using repeated measures to test the effect of FFC-AL. SETTING:Four AL facilities with at least 100 beds. PARTICIP...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1111/j.1532-5415.2011.03699.x

    authors: Resnick B,Galik E,Gruber-Baldini A,Zimmerman S

    更新日期:2011-12-01 00:00:00

  • Prevalence and Preventability of Drug-Related Hospital Readmissions: A Systematic Review.

    abstract:OBJECTIVES:To summarize the evidence on the prevalence and preventability of drug-related hospital readmissions. DESIGN:A systematic review was performed of studies that examined drug-related hospital readmissions. PubMed, EMBASE, and the Cochrane Library were searched from inception through August 2016. Reference lis...

    journal_title:Journal of the American Geriatrics Society

    pub_type: 杂志文章

    doi:10.1111/jgs.15244

    authors: El Morabet N,Uitvlugt EB,van den Bemt BJF,van den Bemt PMLA,Janssen MJA,Karapinar-Çarkit F

    更新日期:2018-03-01 00:00:00