Abstract:
OBJECTIVE:To develop and validate the Time and Change (T&C) test, a simple, standardized method for detecting dementia in a diverse older outpatient population with varying levels of education. DESIGN:A prospective cohort validation study. SETTING:Two outpatient clinics at an urban teaching hospital. PARTICIPANTS:The concurrent validation sample consisted of 100 consecutive outpatients 70 years of age or older who were 58% non-white and had a 16% dementia prevalence rate and educational levels ranging from 0 to 17+ years. Reliability was tested in a sample of 42 consecutive outpatients 75 years of age or older with a 36% dementia prevalence rate. MEASUREMENTS:T&C ratings were validated against a reference standard based on the Blessed Dementia Rating Scale and the Mini-Mental State Examination. Reliability, contribution to physician recognition of dementia, and ease of use were assessed. RESULTS:In the outpatient setting, the T&C had a sensitivity of 63%, specificity of 96%, a negative predictive value of 93%, a positive predictive value of 77%, and test-retest and inter-observer reliability agreement rates of 95% and 100%, respectively. When T&C results were added to the physician's documentation of dementia, the number of missed cases decreased from 44% to 19%, and the number of overcalled cases decreased by 100%. When timed cut points were added, the T&C test had a sensitivity of 94 to 100%, specificity of 37 to 46%, negative predictive value of 98 to 100%, positive predictive value of 23 to 25%, and test-retest and inter-observer agreement rates of 82% and 70 to 75%, respectively. CONCLUSION:The T&C test is a simple, accurate, reliable, performance-based tool that can improve physician ability to recognize dementia in diverse outpatient populations.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Froehlich TE,Robison JT,Inouye SKdoi
10.1111/j.1532-5415.1998.tb01534.xsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
1506-11issue
12eissn
0002-8614issn
1532-5415journal_volume
46pub_type
杂志文章abstract:OBJECTIVES:To obtain population-based estimates of emergency department (ED) visits by long-term care (LTC) residents. DESIGN:Retrospective cohort study using administrative data. SETTING:All LTC facilities in Ontario, Canada. PARTICIPANTS:All LTC residents who visited an ED at least once during a 6-month period. M...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02736.x
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVES:To investigate long-term variability in serum high-sensitivity C-reactive protein (CRP) and interleukin-6 (IL-6) and to determine associated risk factors for high-risk inflammatory profiles. DESIGN:Prospective population-based cohort study. PARTICIPANTS:Participants (N = 1,443) of the Epidemiology of Heari...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12382
更新日期:2013-08-01 00:00:00
abstract:OBJECTIVES:To estimate infection prevalence and explore associated risk factors in nursing home (NH) residents, individuals receiving home health care (HHC), and individuals receiving hospice care. DESIGN:Cross-sectional. SETTING:Nationally representative samples of 1,174 U.S. NHs in the 2004 National Nursing Home Su...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.12153
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVES:To systematically review the current literature on the pharmacological treatment of postmeal reductions in blood pressure (BP). DESIGN:A systematic literature search and standardized data collection of randomized controlled trials on the pharmacological prevention of postprandial reductions in BP in adults ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/jgs.12728
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVES:To determine how poor sleep affects the health of older ethnic minorities. DESIGN:Cross-sectional study involving a population-based survey. SETTING:Hispanic Established Population for the Epidemiologic Study of the Elderly (H-EPESE) survey conducted in the southwestern United States. PARTICIPANTS:Two tho...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04144.x
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVES:To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults. DESIGN:Double-blind, randomized, controlled clinical trial. SETTING:Clinical research facility. PARTICIPANTS:One hundred ten men and 115 women aged 55 to 85 (mean +/- ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2008.01768.x
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To compare perioperative problems and outcomes of reconstructive surgery with microvascular flaps of a group of older (≥ 70) and younger adults (20-69). DESIGN:Prospective clinical cohort study. SETTING:Maxillofacial surgical unit of a university teaching hospital in Munich, Germany. PARTICIPANTS:Two hund...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2011.03315.x
更新日期:2011-03-01 00:00:00
abstract:OBJECTIVES:To investigate the natural history, cause of death, and end-of-life experiences of individuals diagnosed with dementia with Lewy bodies (DLB). DESIGN:Twenty-question online survey administered through the Lewy Body Dementia Association. SETTING:United States. PARTICIPANTS:Caregivers, family, and friends o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15608
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To determine whether low serum B12 levels are associated with an increased incidence of dementing illness. DESIGN:Longitudinal cohort study, 5-year follow-up. PARTICIPANTS:Volunteer cohort of 410 nondemented ambulatory subjects aged 75 to 85 years. MEASUREMENTS:Annual serum B12 determinations and neuropsyc...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb06583.x
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:To describe the total cost of pressure ulcer prevention, component costs of each intervention, and the relationship of costs to subjects' risk level. DESIGN:3-month cohort trial. SETTING:A 600-bed, state-supported, long-term care facility. PATIENTS:A total of 539 war veterans, 83% of whom were male; mean a...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb06095.x
更新日期:1995-05-01 00:00:00
abstract::Absorption of folates, vitamin B6, pantothenate, and riboflavin from a natural food source (yeast) and from synthetic folylmonoglutamate was studied in 24 elderly subjects (age range, 73 to 101 years) and in 12 healthy younger subjects (age range, 24 to 42 years). All subjects absorbed riboflavin, vitamin B6, and pant...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1978.tb01962.x
更新日期:1978-05-01 00:00:00
abstract:OBJECTIVES:To determine whether severe obesity in older people is independently associated with diminished lower extremity physical performance (LEP) in a random sample of homebound older adults that were considered ambulatory. DESIGN:Prospective cohort with 1 year of follow-up (2000-02). SETTING:In-home assessments ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2006.00842.x
更新日期:2006-09-01 00:00:00
abstract:OBJECTIVES:To confirm associations of apolipoprotein E (ApoE) ε4 carrier status, sex, and time-dependent cognitive status with mortality risk and to investigate these joint effects of these associations in a cohort of community-dwelling U.S. adults. DESIGN:Prospective cohort study. SETTING:The Baltimore Longitudinal ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12156
更新日期:2013-04-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01418.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:To compare longitudinal changes in healthcare costs between fallers admitted to the hospital at the time of the fall (admitted), those not admitted to the hospital (nonadmitted), and nonfaller controls; test hypotheses related to differences in mean costs between and within these groups over time; and estima...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2010.02816.x
更新日期:2010-05-01 00:00:00
abstract::Ethical issues surrounding decisions to limit treatment often focus on dramatic and highly technical interventions, such as mechanical ventilation. Many less dramatic forms of therapy are considered routine, and ethical aspects of their use may be less closely examined. Nutritional support can be crucially important i...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1984.tb02009.x
更新日期:1984-03-01 00:00:00
abstract:OBJECTIVE:To determine the influences of age and risk group on the survival of AIDS patients. We concentrated on transfusion because it is the commonest risk factor for AIDS in patients over 70 years of age. DESIGN:Survival curve regression analysis. PARTICIPANTS:Patients aged 13 years and over with AIDS acquired thr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb06694.x
更新日期:1993-03-01 00:00:00
abstract:OBJECTIVES:To quantify the relationship between indwelling devices (urinary catheters, feeding tubes, and peripherally inserted central catheters) and carriage of antimicrobial-resistant pathogens in nursing home residents. DESIGN:Cross-sectional. SETTING:Community nursing home in Southeast Michigan. PARTICIPANTS:Re...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01468.x
更新日期:2007-12-01 00:00:00
abstract::Identifying impairments in the capacity to make and execute decisions is critical to the assessment and remediation of elder self-neglect. Few capacity assessment tools are available for use outside of healthcare settings, and none have been validated in the context of elder self-neglect. Health and social services pr...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2008.01979.x
更新日期:2008-11-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.14878
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To investigate the association between African and Native American genomic ancestry and long-term cognitive trajectories in admixed Brazilians. DESIGN:Population-based longitudinal study. SETTING:Bambui-Epigen (Brazil) cohort study. PARTICIPANTS:Adults aged 60 and older (N=1,215) MEASUREMENTS: Participant...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15504
更新日期:2018-10-01 00:00:00
abstract::In reviewing the literature on treatment approaches with the psychiatric elderly, a large number of studies were found which espouse comprehensive rehabilitation programs that usually require supplementation of existing personnel and expansion of facilities. Although some agencies and institutions are fortunate in sec...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1977.tb00648.x
更新日期:1977-07-01 00:00:00
abstract:OBJECTIVES:Only limited data are available regarding smoking and health in later life and, in particular, in the older Chinese population. This paper reports the relationship between smoking and mortality in a Chinese cohort aged 70 years and older. SETTING:A population-based study conducted in Hong Kong. PARTICIPANT...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1999.tb01565.x
更新日期:1999-12-01 00:00:00
abstract:OBJECTIVES:To compare the frequency and characteristics of septic arthritis in patients younger than 80 and aged 80 and older. DESIGN:Retrospective. SETTING:Single hospital center. PARTICIPANTS:Patients admitted between 1979 and 2002 for septic arthritis. MEASUREMENTS:Age, sex, time to diagnosis, predisposing facto...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53373.x
更新日期:2005-07-01 00:00:00
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journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16790
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVE:To study advance directives (code status) among subgroups of Asian nursing home residents. DESIGN:Cross-sectional design. PARTICIPANTS AND SETTING:A total of 423 residents of Asian descent (aged >55) from two ethnic nursing homes in Seattle, Washington. METHODS:Chart review was conducted on 423 residents (...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2000.tb05003.x
更新日期:2000-05-01 00:00:00
abstract:OBJECTIVES:To examine the neuropsychological and clinical profile of help-seekers in an early-detection community dementia program and to explore any relationship between profiles and time to seek help. DESIGN:Cross-sectional. SETTING:Early-detection community dementia program. PARTICIPANTS:Help-seekers (N = 1,005) ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13938
更新日期:2016-03-01 00:00:00
abstract:OBJECTIVES:To apply diagnostic criteria for mild cognitive impairment (MCI) to a geographically representative sample, to estimate the prevalence of MCI, and to estimate 10-year trajectories of incident disability for cognitively intact participants and subgroups with MCI. DESIGN:Prospective cohort; 10 years of follow...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.53566.x
更新日期:2005-11-01 00:00:00
abstract:UNLABELLED:Geriatric assessment units have improved pharmacotherapy for their patients by decreasing the number of medications prescribed. The Senior Care Study, a randomized controlled trial, compared a multidisciplinary-team approach to patient care to the standard medical practice of the institution. As a part of th...
journal_title:Journal of the American Geriatrics Society
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1532-5415.1990.tb01369.x
更新日期:1990-10-01 00:00:00
abstract:OBJECTIVE:The Health Care Surrogate Act (HCSA) in Illinois has been proposed as a model for state laws naming surrogate medical decision-makers for those without advance directives (ADs). Our objective was to determine if the HCSA identifies the same surrogate as older persons would choose for themselves. If not, is th...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb02437.x
更新日期:1996-02-01 00:00:00