Abstract：
OBJECTIVES:To systematically review the current literature on the pharmacological treatment of postmeal reductions in blood pressure (BP). DESIGN:A systematic literature search and standardized data collection of randomized controlled trials on the pharmacological prevention of postprandial reductions in BP in adults using MEDLINE (1950-), EMBASE (1980-), and CINAHL databases was conducted up to July 2013. Bibliographies of relevant reports were also hand-searched to identify all potentially eligible studies. SETTING:Systematic review of randomized controlled trials using PRISMA guidelines. MEASUREMENTS:Articles were assessed using the Critical Appraisal Skills Programme for randomized controlled trials. RESULTS:Thirteen articles reporting 12 studies (1 study was reported in 2 articles) demonstrated that caffeine (5 studies); acarbose; 3,4-DL-threo-dihydroxyphenylserine; guar gum (3 studies); and octreotide (2 studies) statistically attenuated the postprandial reduction in BP. One caffeine study did not show this. Most studies did not include individuals with symptomatic postprandial hypotension (PPH), so interpretation and application of these findings to this patient group should be made with caution. For symptomatic participants, there was improvement with acarbose but none with caffeine. Differences in the way the data were presented in the studies did not allow for quantification of treatment effects using meta-analysis. CONCLUSION:Drug interventions can attenuate postprandial reductions in BP, but they may not necessarily be effective in people with symptomatic PPH.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Ong AC,Myint PK,Potter JFdoi
10.1111/jgs.12728subject
Has Abstractpub_date
2014-04-01 00:00:00pages
649-61issue
4eissn
0002-8614issn
1532-5415journal_volume
62pub_type
杂志文章,评审abstract：:Long-term acute care (LTAC) represents a rapidly growing category of Medicare providers, but little is known about its quality, outcomes, and cost-effectiveness. Its defining characteristic, as set by Medicare, is an average length of stay of greater than 25 days. Modern LTAC emerged in the early 1980s as a setting fo...
journal_title：Journal of the American Geriatrics Society
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更新日期：2007-05-01 00:00:00
abstract：OBJECTIVES:To describe the prevalence of diabetes mellitus (DM) in centenarians. DESIGN:Cross-sectional, population-based. SETTING:Forty-four counties in northern Georgia. PARTICIPANTS:Two hundred forty-four centenarians (aged 98-108, 15.8% male, 20.5% African American, 38.0% community dwelling) from the Georgia Cen...
journal_title：Journal of the American Geriatrics Society
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1984.tb02009.x
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abstract：:Low-income older adults are particularly vulnerable during care transitions. The present study evaluated the effectiveness of a transitional care model in this population. A quasi-experimental design was used to compare outcomes in the intervention group with historical controls at 30, 90, 180, and 365 days after disc...
journal_title：Journal of the American Geriatrics Society
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journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.1999.tb02991.x
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journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.1999.tb01583.x
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journal_title：Journal of the American Geriatrics Society
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doi：10.1046/j.1532-5415.2002.50519.x
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abstract：:A medical examiner's series of 71 elderly patients with fatal internal cerebral injuries demonstrated age differences with respect to the type of cerebral lesion and the causal incident. The elderly showed relatively fewer severe cerebral contusions than did a young group, but a higher incidence of subdural and intrap...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1978.tb03332.x
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abstract：OBJECTIVES:To describe the features of community-acquired pneumonia (CAP) requiring hospitalization in subjects receiving home care. DESIGN:Prospective study from November 15, 2000, to November 14, 2002. SETTING:Six hospitals in the Edmonton, Canada, area. PARTICIPANTS:Two thousand four hundred sixty-four subjects a...
journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.2005.53264.x
更新日期：2005-05-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.1998.tb02540.x
更新日期：1998-02-01 00:00:00
abstract：:Arguments have been made that the culture of nursing homes (NHs) must change to improve the quality of care, and two initiatives have been designed to accomplish this goal. One initiative is to provide resident outcome information (quality indicators) to NH management and consumers via public reporting systems. This i...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2004.52372.x
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVES:Use of objectively measured physical activity (PA) in older adults to assess relationship between PA and risk of all-causes mortality is scarce. This study evaluated the associations of PA based on accelerometry and a questionnaire with the risk of mortality among older adults from a city in Southern Brazil....
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pub_type： 杂志文章
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journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1532-5415.2000.tb04993.x
更新日期：2000-05-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03576.x
更新日期：2011-09-01 00:00:00
abstract：:What ethical concerns regarding the application of new antidementia compounds are pertinent to the best interests of patients with Alzheimer's disease and their caregivers? Based on collected preliminary anecdotal accounts, these concerns are important and should be considered carefully by clinicians, researchers, and...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1998.tb03819.x
更新日期：1998-06-01 00:00:00
abstract：:As part of a study of long-term institutional care of the elderly, this report presents salient data concerning 193 elderly applicants. Physicians play an important role in decisions to apply for such care. More than half of the applicants and about 80% of their family members approved of the proposed move. The number...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1976.tb04293.x
更新日期：1976-04-01 00:00:00
abstract：:The current literature on suicide by medicinal overdose among the elderly population of the United States and Britain is discussed. The older white male is a high risk in this regard. Physical and mental illnesses contribute to the problem of suicide among the aged, and some of the drugs prescribed for treatment (e.g....
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.1975.tb00218.x
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journal_title：Journal of the American Geriatrics Society
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journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.1984.tb06138.x
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journal_title：Journal of the American Geriatrics Society
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doi：10.1111/j.1532-5415.1981.tb01236.x
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abstract：OBJECTIVES:To identify fracture types in a series of older adults with pelvic fractures and to determine whether the type of pelvic fracture affected short-term outcomes and morbidity. DESIGN:Retrospective chart review. SETTING:Teaching hospital. PARTICIPANTS:One hundred eighty-one individuals aged 65 and older with...
journal_title：Journal of the American Geriatrics Society
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更新日期：2011-07-01 00:00:00
abstract：OBJECTIVES:To understand the potential roles of various patient and provider factors in the underuse of pneumococcal vaccination in Medicare-eligible older African Americans. DESIGN:The Cardiovascular Health Study. SETTING:Four U.S. states. PARTICIPANTS:Seven hundred ninety-five pairs of community-dwelling Medicare-...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章,多中心研究
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更新日期：2010-12-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 临床试验,杂志文章
doi：10.1111/j.1532-5415.1985.tb02856.x
更新日期：1985-01-01 00:00:00
abstract：OBJECTIVE:To determine the excess mortality associated with obesity (defined by body mass index (BMI)) in older people, with and without adjustment for other risk factors associated with mortality and for demographic factors. DESIGN:Retrospective cohort analysis of the Longitudinal Study of Aging (LSOA). SETTING:Nati...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
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更新日期：2001-07-01 00:00:00
abstract：OBJECTIVES:To examine relationships between race and psychotropic drug use (antidepressant, antianxiety, sedative/hypnotic agents) in informal caregivers with symptoms of depression who provide care for elderly relatives with progressive dementia. Whether racial differences in medication use relate to racial difference...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2005.53155.x
更新日期：2005-03-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03499.x
更新日期：2011-08-01 00:00:00
abstract：OBJECTIVES:To investigate the association between African and Native American genomic ancestry and long-term cognitive trajectories in admixed Brazilians. DESIGN:Population-based longitudinal study. SETTING:Bambui-Epigen (Brazil) cohort study. PARTICIPANTS:Adults aged 60 and older (N=1,215) MEASUREMENTS: Participant...
journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
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更新日期：2018-10-01 00:00:00
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journal_title：Journal of the American Geriatrics Society
pub_type： 杂志文章
doi：10.1111/j.1532-5415.2011.03661.x
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:Quality of human immunodeficiency virus (HIV) care in nursing homes (NHs) has never been measured. DESIGN:A cross-sectional study. SETTING:NHs. PARTICIPANTS:A total of 203 NHs and 1375 persons living with HIV. MEASUREMENTS:Medicare claims from 2011 to 2013 were linked to assessments of resident health, p...
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更新日期：2020-06-01 00:00:00
