Abstract:
OBJECTIVES:To assess mobility disability trajectories before death in a large sample of very old adults using two analytical approaches to determine how well they corresponded. DESIGN:Decedent sample from the Health, Aging and Body Composition (Health ABC) Study. Data were collected between 1997 and 2015. SETTING:Pittsburgh, Pennsylvania, and Memphis, Tennessee. PARTICIPANTS:Individuals randomly selected from well-functioning white Medicare beneficiaries and all black community residents meeting age criteria (70-79) (N = 3,075). MEASUREMENTS:Participants were interviewed in person or by phone at least every six months throughout the study. Of the 1,991 participants who died by the end of the study, 1,410 had been interviewed for 3 years before death, including an interview 6 months before dying. We analyzed self-reported mobility collected prospectively at 6-month intervals during the last 3 years of life. We derived trajectories in two ways: by averaging decline within decedent groups prespecified according to clinical conditions and by estimating trajectory models using maximum-likelihood semiparametric modeling. RESULTS:Ninety-eight percent of decedents were classified according to 4 prespecified clinical conditions (sudden death, terminal, organ failure, frailty), which produced groups with different characteristics. Five disability trajectories were identified: late decline, progressive disability, moderate disability, early decline, and persistent disability. Disability trajectory and clinical condition grouping confirmed previous research but were only marginally related. CONCLUSION:Derived disability trajectories and grouping according to clinical condition provide useful information about different facets of the end-of-life experience. The lack of fit between them suggests a need for greater attention to heterogeneity in disability in the period before death.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Lunney JR,Albert SM,Boudreau R,Ives D,Satterfield S,Newman AB,Harris T,Health Aging and Body Composition Study.doi
10.1111/jgs.15224subject
Has Abstractpub_date
2018-03-01 00:00:00pages
503-508issue
3eissn
0002-8614issn
1532-5415journal_volume
66pub_type
杂志文章abstract:OBJECTIVES:To compare the diagnosis and management of urinary tract infection (UTI) in hospitalized older people with clinical criteria and therapeutic guidelines. DESIGN:A retrospective case series of emergency hospital admissions collected over an 18-month period. SETTING:An acute general hospital in northwest Engl...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2008.02073.x
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To examine whether the total burden of comorbidity and pattern of co-occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF-P) or HF with reduced LVEF (HF-R). DESIGN:Cross-sectional cohort study. SETTING:Four participating health plan...
journal_title:Journal of the American Geriatrics Society
pub_type: 历史文章,杂志文章,多中心研究
doi:10.1111/jgs.12062
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:To investigate the natural history, cause of death, and end-of-life experiences of individuals diagnosed with dementia with Lewy bodies (DLB). DESIGN:Twenty-question online survey administered through the Lewy Body Dementia Association. SETTING:United States. PARTICIPANTS:Caregivers, family, and friends o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15608
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVES:To examine associations between inflammation and physical function and potential mediation by white matter hyperintensities (WMHs) in African Americans (AAs) and European Americans (EAs). DESIGN:Cross-sectional analysis using linear and logistic models with generalized estimating equations to account for fa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.14229
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence of self-harm, suicidal ideation (SI), and suicide attempts (SA) in older adults in the emergency department (ED), including differences according to age, sex, and race and ethnicity. DESIGN:Quasi-experimental, multiphase, eight-center study with prospective review of consecutive c...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.14529
更新日期:2016-10-01 00:00:00
abstract:OBJECTIVES:To ascertain whether a safe-transportation program can change driving exposure while maintaining community participation of older drivers. DESIGN:Randomized controlled trial. SETTING:Northwest Sydney. PARTICIPANTS:Drivers aged 75 and older (mean 80 ± 4) (n = 380). INTERVENTION:Intervention group particip...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.14550
更新日期:2017-03-01 00:00:00
abstract::On September 11, 1986, the Supreme Judicial Court of Massachusetts, in a 4-3 decision, authorized removal of the artificial feeding tube. It held that the "substituted judgment" of an incompetent person in a persistent vegetative state to refuse artificially administered sustenance must be honored. The Court also refu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:To optimize health and well-being for all older people, we must collectively develop leaders to pioneer models of care, educate the healthcare workforce, advance research, and engage the community. METHODS:The Emerging Leaders in Aging (ELIA) program was created to train a multiprofessional cadre...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15702
更新日期:2019-03-01 00:00:00
abstract::The management of older patients with chronic medical conditions dominates medical practice. Cardiovascular disease (CVD) and diabetes mellitus type 2 (DM) in patients aged 65 and older have reached epidemic proportions. Using elements of the Chronic Care Model (CCM), a quality improvement project was undertaken to re...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01320.x
更新日期:2007-10-01 00:00:00
abstract:OBJECTIVES:To investigate whether anticholinergic burden scores from nine published anticholinergic scales are associated with adverse health outcomes, including hospital admissions, hospitalizations for falls, hospital length of stay (LOS), and more visits to general practitioners (GPs). DESIGN:Pharmacoepidemiologica...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13206
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:To assess clinical outcomes and identify risk factors for mortality in older adults with Staphylococcus aureus bloodstream infection (SAB). DESIGN:Retrospective review. SETTING:University of Michigan Health System, Ann Arbor. PARTICIPANTS:All patients aged 80 and older with SAB between January 2004 and Ju...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2009.02666.x
更新日期:2010-02-01 00:00:00
abstract::The purpose of this study was to compare attitudes toward the use of long-term care between older Japanese Americans (n = 1,244) and older Caucasian Americans (n = 1,354). When presented with a hypothetical situation in which they have dementia, 39% of older Japanese Americans and 42% of older Caucasians intended to b...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2002.50275.x
更新日期:2002-06-01 00:00:00
abstract::Newly enacted Federal regulations have focused increasing attention on the use of psychoactive drugs and on the treatment of disruptive behavior in the nursing home. To study the interaction between resident behavior and staff distress in nursing homes, we measured the frequency of seven types of behavior problems amo...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1991.tb02702.x
更新日期:1991-08-01 00:00:00
abstract::Measurements were made of the overnight mobility of a group of elderly hospital patients whose clinical status had been assessed using the Norton clinical assessment score. The number of movements on the first two nights after admission differed from subsequent nights. There was a significant correlation between mobil...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1986.tb04903.x
更新日期:1986-09-01 00:00:00
abstract:OBJECTIVES:To estimate the cost-effectiveness of an intervention to increase pneumococcal, influenza, and pertussis-containing vaccine uptake in adults aged 65 and older in primary care practices. DESIGN:Markov decision analysis model, comparing the cost-effectiveness of the 4 Pillars Practice Transformation Program w...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1111/jgs.14588
更新日期:2017-04-01 00:00:00
abstract:OBJECTIVES:Older patients with asthma or chronic obstructive pulmonary disease are particularly susceptible to exacerbations that may be associated with incorrect use of inhalers. Educational programs with inhaler technique review seem to be effective, but no studies have addressed their cost-effectiveness in older adu...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15834
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVES:To compare the efficacy of a computer-based physical activity program (Embodied Conversational Agent-ECA) with that of a pedometer control condition in sedentary older adults. DESIGN:Single-blind block-randomized controlled trial stratified according to clinic site and health literacy status. SETTING:Three...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/jgs.12449
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:To determine the validity of the Minimum Data Set (MDS). DESIGN:MDS domain scores were correlated with a variety of independently obtained measures of basic behavioral and mental health functions of 513 nursing home residents. SETTING:All participants were residents of the Philadelphia Geriatric Center. PA...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1998.tb03809.x
更新日期:1998-06-01 00:00:00
abstract:BACKROUND:Baseline depressive symptoms have been consistently associated with the onset of cardiovascular disease (CVD). OBJECTIVES:Since depressive symptoms vary over time in elderly persons, and to help clarify whether or not depression is an etiological factor for CVD, we quantified the association between the cour...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/jgs.13872
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:The Health Care Surrogate Act (HCSA) in Illinois has been proposed as a model for state laws naming surrogate medical decision-makers for those without advance directives (ADs). Our objective was to determine if the HCSA identifies the same surrogate as older persons would choose for themselves. If not, is th...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1996.tb02437.x
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVES:To examine the effects of dehydroepiandrosterone (DHEA) supplementation on cognitive function and quality of life in healthy older adults. DESIGN:Double-blind, randomized, controlled clinical trial. SETTING:Clinical research facility. PARTICIPANTS:One hundred ten men and 115 women aged 55 to 85 (mean +/- ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2008.01768.x
更新日期:2008-07-01 00:00:00
abstract:OBJECTIVES:To assess the prevalence of protocols or guidelines for selected domains of inpatient care for older adults; to explore associations between hospital characteristics and adoption of these guidelines or protocols. DESIGN:Telephone- and Web-based questionnaire. SETTING:General acute care hospitals in Pennsyl...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2010.03056.x
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To assess the satisfaction of surrogate decision-makers with the decision to place feeding tubes in elderly patients with impaired decision-making capacity. DESIGN:Inception cohort followed for 5 weeks. SETTING:Four hospitals in the greater Los Angeles area. PARTICIPANTS:Fifty-eight surrogate decision-make...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1994.tb04946.x
更新日期:1994-02-01 00:00:00
abstract::In 13 elderly patients, 12 of whom had Parkinson's disease, visual hallucinations and delirium developed as a side effect of amantadine hydrochloride (Symmetrel) therapy. The symptoms promptly disappearred when amantadine was discontinued. Thereafter, each parkinsonian patient was treated satisfactorily with levo-dopa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1975.tb00187.x
更新日期:1975-05-01 00:00:00
abstract:OBJECTIVES:To develop and validate a prognostic case finding tool that classifies the risk of emergency department (ED) use in an older home care population. DESIGN:Population-based retrospective cohort study using routinely collected data from home care clinical assessments linked prospectively to ED records. SETTIN...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.13336
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Although frailty status is dynamic, whether improvements in frailty predict mortality is unknown. OBJECTIVE:Describe 1-year changes in a frailty index (FI) and association with 48-month mortality. DESIGN:Secondary analysis of the National Health in Aging Trends Study. SETTING:Community. PARTICIPANTS:Five...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.17002
更新日期:2020-12-29 00:00:00
abstract:BACKGROUND/OBJECTIVES:Depression screening and treatment for older adults are recommended in Age-Friendly Health Systems. Few studies have evaluated the association between depressive symptoms and postoperative functioning. We aimed to determine the association between varying levels of depressive symptoms in the preop...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16781
更新日期:2020-12-01 00:00:00
abstract:OBJECTIVES:To determine whether the characteristics of the usual medical care providers of older antidepressant users changed between 1986 and 1997 with the introduction of selective serotonin reuptake inhibitors. DESIGN:Longitudinal study. SETTING:Five-county Piedmont area of North Carolina. PARTICIPANTS:Stratified...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,多中心研究
doi:10.1111/j.1532-5415.2006.00737.x
更新日期:2006-06-01 00:00:00
abstract:OBJECTIVES:To examine the associations between typology of family relationship and risk of elder mistreatment (EM). DESIGN:Population-based epidemiological cross-sectional study. SETTING:Community-dwelling older adults in the greater Chicago area. PARTICIPANTS:A total of 3157 US older Chinese immigrants. MEASUREMEN...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15892
更新日期:2019-08-01 00:00:00
abstract::Urinary incontinence and other lower urinary tract symptoms exert a major influence on the health and independence of frail older people. Detrusor underactivity (DU) is defined as a contraction of reduced strength and/or duration, resulting in prolonged bladder emptying and/or a failure to achieve complete bladder emp...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2006.00917.x
更新日期:2006-12-01 00:00:00