Abstract:
OBJECTIVES:To estimate the cost-effectiveness of an intervention to increase pneumococcal, influenza, and pertussis-containing vaccine uptake in adults aged 65 and older in primary care practices. DESIGN:Markov decision analysis model, comparing the cost-effectiveness of the 4 Pillars Practice Transformation Program with no intervention. SETTING:Diverse primary care practices in two U.S. cities. PARTICIPANTS:Clinical trial participants aged 65 and older. MEASUREMENTS:Quality-adjusted life years (QALYs), public health outcomes, and costs. Vaccination rates and intervention costs were derived from a randomized controlled cluster trial. Other parameters were derived from the medical literature and Centers for Disease Control and Prevention data. All parameters were individually and simultaneously varied over their distributions. RESULTS:With the intervention program and extrapolating over 10 years, there would be approximately 60,920 fewer influenza cases, 2,031 fewer pertussis cases, and 13,842 fewer pneumococcal illnesses in adults aged 65 and older. Total per-person vaccination and illness costs with the intervention were $23.93 higher than without the intervention, with a concurrent increase in effectiveness of 0.0031 QALYs, or $7,635 per QALY gained. In sensitivity analyses, no individual parameter variation caused the intervention to cost more than $50,000 per QALY gained. CONCLUSIONS:Implementing an intervention based on the 4 Pillars Practice Transformation Program is a cost-effective undertaking in primary care practices for individuals aged 65 and older, with predicted public health benefits.
journal_name
J Am Geriatr Socjournal_title
Journal of the American Geriatrics Societyauthors
Smith KJ,Zimmerman RK,Nowalk MP,Lin CJdoi
10.1111/jgs.14588subject
Has Abstractpub_date
2017-04-01 00:00:00pages
763-768issue
4eissn
0002-8614issn
1532-5415journal_volume
65pub_type
杂志文章,多中心研究,随机对照试验abstract::The management of older patients with chronic medical conditions dominates medical practice. Cardiovascular disease (CVD) and diabetes mellitus type 2 (DM) in patients aged 65 and older have reached epidemic proportions. Using elements of the Chronic Care Model (CCM), a quality improvement project was undertaken to re...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2007.01320.x
更新日期:2007-10-01 00:00:00
abstract::From this discussion, several conclusions can be drawn. First, with advancing age there is a decrease in cardiovascular responsiveness and, more specifically, there is a decrease in catecholamine-stimulated chronotropic and inotropic responses. This decreased function has its biochemical correlate in the observation t...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.1985.tb04890.x
更新日期:1985-03-01 00:00:00
abstract:OBJECTIVE:To examine the predictive value of psychosocial factors as risk factors for all-cause mortality. DESIGN:A community-based longitudinal cohort study: The Honolulu Heart Program. SETTING:Population-based study conducted in Oahu, Hawaii. PARTICIPANTS:Three thousand four hundred and ninety-seven men age 71 to ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2001.49148.x
更新日期:2001-06-01 00:00:00
abstract:OBJECTIVES:To quantify incidence of tooth loss, prosthodontic dental restoration, and chewing difficulty onset and the effect of tooth loss and prosthodontic restoration on chewing difficulty onset. DESIGN:A prospective cohort study of oral health and related behaviors with in-person interviews and clinical examinatio...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52253.x
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVES:To determine whether hospital costs are higher in patients with lower functional status at admission, defined as dependence in one or more activities of daily living (ADLs), after adjustment for Medicare Diagnosis-Related Group (DRG) payments. DESIGN:Prospective study. SETTING:General medical service at a ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51556.x
更新日期:2003-12-01 00:00:00
abstract::Falls incidence in Chinese older people has been reported to be approximately half that of Caucasian populations. It is possible that the falls risk factor profile may differ significantly between Caucasian and Chinese populations, and a better understanding of this reported difference in incidence and associated risk...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,评审
doi:10.1111/j.1532-5415.2010.03286.x
更新日期:2011-03-01 00:00:00
abstract::Tardive dyskinesia has emerged as a considerable public health hazard. In view of the overwhelming evidence that the elderly are particularly susceptible to this complication of neuroleptic use and the fact that there is no really effective treatment, neuroleptics should be avoided whenever possible in elderly patient...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1983.tb05417.x
更新日期:1983-02-01 00:00:00
abstract:OBJECTIVE:To investigate the prevalence of hypoalbuminemia and hypoprealbuminemia in hospitalized, elderly, skilled nursing facility residents and to correlate these findings with clinical outcomes. DESIGN:Prospective cohort study. SETTING:A 300-bed community hospital. PARTICIPANTS:Eighty-one hospitalized, skilled n...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb01893.x
更新日期:1993-05-01 00:00:00
abstract::Senile dementia is one of the important medical-social-economic problems facing our society, estimated to affect some 60% of nursing home patients and of persons residing in the community. The course of dementia in these patients is affected not only by their age, medical complications, and the disease itself, but als...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1981.tb01261.x
更新日期:1981-12-01 00:00:00
abstract:OBJECTIVES:To examine rates and predictors of lifetime and recent depression treatment in a sample of 1,801 depressed older primary care patients DESIGN:Cross sectional survey data collected from 1999 to 2001 as part of a treatment effectiveness trial. SETTING:Eighteen primary care clinics belonging to eight organiza...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.1532-5415.2003.51159.x
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVES:To compare the prevalence and predictors of caregiver esteem and burden during two different stages of care recipients' illnesses-advanced chronic illness and the last year of life. DESIGN:Longitudinal, observational cohort study. SETTING:Community sample recruited from outpatient clinics at Duke Universit...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12841
更新日期:2014-06-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence of prefrailty, frailty, comorbidity, and disability in the youngest old and to identify chronic diseases associated with individual frailty criteria. DESIGN:Population-based cohort study of noninstitutionalized elderly adults at baseline; cross-sectional analysis. SETTING:Lausann...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2012.04113.x
更新日期:2012-09-01 00:00:00
abstract:OBJECTIVES:To estimate the prevalence of diagnosed traumatic brain injury (TBI) in individuals hospitalized with hip fracture and examine its association with all-cause mortality. DESIGN:Nested cohort study. SETTING:National sample of Medicare beneficiaries from 2006 to 2010. PARTICIPANTS:Beneficiaries aged 65 and o...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15661
更新日期:2019-01-01 00:00:00
abstract::Primary carcinoma of the appendix, though rare, occurs often enough to warrant its inclusion in diagnostic possibilities when the symptoms of acute appendicitis, without leukocytosis, are present in geriatric patients. A case of mucinous adenocarcinoma of the appendix in an 88-year-old white woman is presented. The su...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1982.tb05665.x
更新日期:1982-09-01 00:00:00
abstract:OBJECTIVES:Lower than recommended doses of direct-acting oral anticoagulants are often prescribed to older adults with nonvalvular atrial fibrillation (NVAF). Our goal was to determine the consequences of lower than recommended dosing on plasma apixaban concentrations during the clinical care of older adults with NVAF....
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15982
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:To compare the ability of five measures of comorbidity to predict mortality and incident disability in basic activities of daily living (BADLs) in unselected older persons. DESIGN:An assessment of the data obtained from the Insufficienza Cardiaca negli Anziani Residenti a Dicomano (ICARe Dicomano) Study, a ...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2005.00572.x
更新日期:2006-02-01 00:00:00
abstract:OBJECTIVE:To examine public opinion regarding certain elements of consent: disclosure, advance directives, substitute decisions, emergency treatment, and advocacy. DESIGN:Cross-sectional random-digit-dialing telephonic survey. SETTING:General public. PARTICIPANTS:One thousand randomly-selected adults living in Ontar...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1993.tb02042.x
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:To describe the long-term outcome and complications of spinal surgery in a population of elderly patients. DESIGN:Retrospective chart review and clinical follow-up. SETTING:A 700-bed tertiary care midwestern hospital. PATIENTS:Patients 70 years of age or older who underwent elective surgical procedures for...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb01981.x
更新日期:1992-09-01 00:00:00
abstract:OBJECTIVE:To determine predictors of 2-year post-hospitalization mortality in a cohort of elderly hospitalized patients originally assembled to assess the impact of a Geriatric Consultation Team (GCT). DESIGN:Two-year follow-up of an inception cohort. SETTING:University-affiliated tertiary care VA Medical Center. PA...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1992.tb03648.x
更新日期:1992-12-01 00:00:00
abstract::Quality-of-life considerations in physicians' decisions on life-sustaining therapy were explored using a patient management problem (PMP) depicting acute respiratory failure in an elderly man with chronic pulmonary disease; 205 internal medicine and family medicine physicians were interviewed. The physicians' percepti...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1985.tb07135.x
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between total cholesterol (TC) and low-density lipoprotein cholesterol (LDL-C) and the incidence of coronary heart disease (CHD) in elderly men. DESIGN:Prospective. SETTING:Population based. PARTICIPANTS:A sample of 2,424, Japanese-American men aged 71 to 93 was used. MEASUREM...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.2004.52551.x
更新日期:2004-12-01 00:00:00
abstract::The aim of this study was to evaluate the usefulness of Silver's Cerebral Function Test in predicting the management and placement of patients admitted to a psychogeriatric hospital. Overall, 205 consecutively admitted patients and 54 age-matched controls living in the community were examined, thereby greatly extendin...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1977.tb00409.x
更新日期:1977-06-01 00:00:00
abstract::The relationship between atrial natriuretic peptide (ANP) and age was studied. In elderly subjects (65 to 84 years) higher basal ANP levels were found as compared with those found in young subjects (21 to 23 years). Volume loading (750 mL 0.9% NaCl in 60 minutes) increased ANP levels only in the aged group, and plasma...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1990.tb01502.x
更新日期:1990-11-01 00:00:00
abstract:OBJECTIVE:To determine the internal validity of the physical activity index (PAI). DESIGN:Three time periods over a 26-year period (1965/68 examination, n = 7911; 1980/82 examination, n = 2054; 1991/93 examination, n = 3425). SETTING:Honolulu, Hawaii. PARTICIPANTS:Middle-aged to older Japanese-American men. MEASURE...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/j.1532-5415.1995.tb05564.x
更新日期:1995-09-01 00:00:00
abstract:OBJECTIVES:To examine differences in a proxy measure of muscle quality across the adult life span and explore potential mechanisms of muscle quality change through identification of cross-sectional correlates of muscle quality. DESIGN:Cross-sectional study. SETTING:Baltimore Longitudinal Study of Aging. PARTICIPANTS...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.12653
更新日期:2014-02-01 00:00:00
abstract:OBJECTIVES:To evaluate national trends in electrocardiogram (EKG) monitoring in Veterans Affairs (VA) beneficiaries prescribed high-dose citalopram before and after the 2011-12 Food and Drug Administration (FDA) safety warnings. DESIGN:Interrupted time-series analyses. SETTING:National VA healthcare system data linke...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.15420
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND/OBJECTIVES:Most forms of dementia are associated with progressive cognitive and noncognitive impairments that can severely affect fitness to drive. Whether safe driving is still possible in the single case, however, is often difficult to decide and may be dependent on both severity and type of the respective...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16077
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Hospital-acquired disability (HAD) is common and often related to low physical activity while in the hospital. OBJECTIVE:To examine whether wearable hospital activity trackers can be used to predict HAD. DESIGN:A prospective observational study between January 2016 and March 2017. SETTING:An academic medi...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1111/jgs.16231
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVES:To evaluate the effect of nine disabling medical conditions upon recovery from functional limitations by elders. DESIGN:Retrospective analysis of prospective longitudinal cohort. SETTING:Community. PARTICIPANTS:Persons aged 65 and older in Framingham Heart Study. MEASUREMENTS:Change in function in elders...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章
doi:10.1046/j.0002-8614.2004.52057.x
更新日期:2004-02-01 00:00:00
abstract:OBJECTIVES:To determine the effect of differing methods of dispensing wheelchairs. DESIGN:Quasi-experimental by day of week. SETTING:Department of Veterans Affairs Medical Center. PARTICIPANTS:Eighty-four community-dwelling, cognitively intact patients prescribed a standard manual wheelchair. INTERVENTION:A multifa...
journal_title:Journal of the American Geriatrics Society
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1532-5415.2005.53502.x
更新日期:2005-10-01 00:00:00