Patterns of comorbidity in older adults with heart failure: the Cardiovascular Research Network PRESERVE study.

Abstract:

OBJECTIVES:To examine whether the total burden of comorbidity and pattern of co-occurring conditions varies in individuals with heart failure (HF) with preserved left ventricular ejection fraction (LVEF) (HF-P) or HF with reduced LVEF (HF-R). DESIGN:Cross-sectional cohort study. SETTING:Four participating health plans within the National Heart, Lung, and Blood Institute-sponsored Cardiovascular Research Network. PARTICIPANTS:All members aged 65 and older with HF based on hospital discharge and ambulatory visit diagnoses. MEASUREMENTS:Participants with a LVEF of 50% or greater were classified as having HF-P. Presence of cardiac and noncardiac comorbidities was obtained from health plan administrative databases. RESULTS:Of 23,435 individuals identified with HF and LVEF information, 53% (12,407) had confirmed HF-P (mean age 79.6; 60% female). More than three-quarters of the sample had three or more co-occurring conditions in addition to HF, and half had five or more cooccurring conditions. Participants with HF-P had a slightly higher burden of comorbidity than those with HF-R (mean 4.5 vs 4.4, P = .002). Patterns of how specific conditions co-occurred did not vary in participants with preserved or reduced systolic function. CONCLUSION:There is a high degree of comorbidity and multiple morbidity in individuals with HF. The burden and pattern of comorbidity varies only slightly in individuals with preserved or reduced LVEF.

journal_name

J Am Geriatr Soc

authors

Saczynski JS,Go AS,Magid DJ,Smith DH,McManus DD,Allen L,Ogarek J,Goldberg RJ,Gurwitz JH

doi

10.1111/jgs.12062

subject

Has Abstract

pub_date

2013-01-01 00:00:00

pages

26-33

issue

1

eissn

0002-8614

issn

1532-5415

journal_volume

61

pub_type

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