Characterization of the mouse Myoc/Tigr gene.

abstract：:The relation between autophagy and Chlamydia trachomatis infection remain inconclusive. In order to further understand the role of autophagy in C. trachomatis-infected cells. Atg5 silenced HeLa229 cell line was used to establish an autophagy inhibition C. trachomatis infection model. The results suggested that Atg5 se...

journal_title：Biochemical and biophysical research communications

authors： Wang F,Zhang L,Lu X,Zhu Q,Shi T,Lu R,Yu P,Zhang H,Wang Y

更新日期：2019-11-26 00:00:00

abstract：:Ribose methylation of eukaryotic rRNA is directed by box C/D small nucleolar RNAs (snoRNAs), which pinpoint the nucleotide to be methylated in specific position within the rRNA sequence. Here, we report the identification of a novel double-guide C/D box snoRNA termed snR88 that directs methylation of two previously un...

journal_title：Biochemical and biophysical research communications

authors： Bi YZ,Qu LH,Zhou H

更新日期：2007-03-02 00:00:00

abstract：:Although the retinal angiogenic and mitogenic factors have been identified to be acidic and basic fibroblast growth factors (aFGF and bFGF), little information has so far been available about the cells producing them and their function in retinal tissues. We found, by in situ hybridization, that the expression pattern...

journal_title：Biochemical and biophysical research communications

authors： Noji S,Matsuo T,Koyama E,Yamaai T,Nohno T,Matsuo N,Taniguchi S

更新日期：1990-04-16 00:00:00

abstract：:Deoxynucleoside analogues (dNAs) are cytotoxic towards both replicating and indolent malignancies. The impact of fluctuations in the metabolism of dNAs in relation to cell cycle could have strong implications regarding the activity of dNAs. Deoxycytidine kinase (dCK) and deoxyguanosine kinase (dGK) are important enzym...

journal_title：Biochemical and biophysical research communications

authors： Fyrberg A,Albertioni F,Lotfi K

更新日期：2007-06-15 00:00:00

abstract：:Many hypothalamic neuropeptides are involved in the regulation of energy homeostasis and feeding behavior. We have investigated whether and to what extent neuropeptide Y (NPY), agouti-related protein (AGRP), melanin-concentrating hormone (MCH), and prepro-orexin (prepro-OX) as well as pro-opiomelanocortin (POMC) and c...

journal_title：Biochemical and biophysical research communications

authors： Bertile F,Oudart H,Criscuolo F,Maho YL,Raclot T

更新日期：2003-04-18 00:00:00

abstract：:We examined the effect of low density lipoprotein (LDL) on histamine release from purified human lung mast cells. LDL inhibited anti-IgE- induced histamine release in a dose-dependent manner, with 100 micrograms/ml LDL-protein inhibiting histamine release by 53 +/- 8% (mean +/- SEM); half-maximal inhibition occurred a...

journal_title：Biochemical and biophysical research communications

authors： Schulman ES,Quinn TJ,Post TJ,O'Donnell P,Rodriguez A,Gonen B

更新日期：1987-10-29 00:00:00

abstract：:Structural determinants of L-[(3)H]nicotine binding to synthetic peptides comprising residues 188-207 of nicotinic acetylcholine receptor alpha subunits were invesitigated by equilibrium binding analysis. Two binding components were detected, one of low affinity (K(d) approximately 1.5 microM) that did not differ sign...

journal_title：Biochemical and biophysical research communications

authors： Lentz TL

更新日期：2000-02-16 00:00:00

abstract：:In this study, we demonstrate that the active site architecture of the human glutathione (GSH) S-transferase Pi (GSTP1-1) accounts for its enantioselectivity in the GSH conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-oxy-7,8,9, 10-tetrahydrobenzo(a) pyrene (anti-BPDE), the ultimate carcinogen of benzo(a)pyrene. F...

journal_title：Biochemical and biophysical research communications

authors： Hu X,O'Donnell R,Srivastava SK,Xia H,Zimniak P,Nanduri B,Bleicher RJ,Awasthi S,Awasthi YC,Ji X,Singh SV

更新日期：1997-06-18 00:00:00

abstract：:Sulfur(S)-starvation was previously shown to induce the degradation of an acidic lipid in chloroplasts, sulfoquinovosyl diacylglycerol (SQDG), to yield a major internal S-source in a green alga, Chlamydomonas reinhardtii. We here found that the synthesis of phosphatidylglycerol (PG), the other acidic lipid in chloropl...

journal_title：Biochemical and biophysical research communications

authors： Sugimoto K,Midorikawa T,Tsuzuki M,Sato N

更新日期：2008-05-02 00:00:00

abstract：:To examine the effects of a replacement of the proximal or the distal histidine on the structure of hemoglobin (Hb), absorption and circular dichroic (CD) spectra of five species of Hbs M in the visible region were measured. Four Hbs M had a characteristic but a similar absorption spectrum upon amino acid substitution...

journal_title：Biochemical and biophysical research communications

authors： Nagai M,Takama S,Yoneyama Y

更新日期：1985-04-30 00:00:00

abstract：:FGF1 and FGF2 support hematopoietic stem and progenitor cells (HSPCs) under stress conditions. In this study, we show that fibroblast growth factor (FGF7) may be a novel niche factor for HSPC support and leukemic growth. FGF7 expression was attenuated in mouse embryonic fibroblasts (MEFs) deficient for the MED1 subuni...

journal_title：Biochemical and biophysical research communications

authors： Ishino R,Minami K,Tanaka S,Nagai M,Matsui K,Hasegawa N,Roeder RG,Asano S,Ito M

更新日期：2013-10-11 00:00:00

abstract：:Peroxisomes catalyze a number of essential metabolic functions especially related to lipid metabolism. There is increasing evidence suggesting that peroxisomes are also involved in the synthesis of isoprenoids via the mevalonate pathway at least in rat liver. In order to obtain independent evidence for a role of perox...

journal_title：Biochemical and biophysical research communications

authors： Wanders RJ,Romeijn GJ

更新日期：1998-06-29 00:00:00

abstract：:Cell cycle arrest is essential for initiation of muscle differentiation in myoblasts. Given the previously described essential role for p38 MAPK in myogenesis, we undertook the present study to investigate the role of p38 MAPK in the cell cycle arrest that initiates muscle differentiation. p38 MAPK activity increased ...

journal_title：Biochemical and biophysical research communications

authors： Lee J,Hong F,Kwon S,Kim SS,Kim DO,Kang HS,Lee SJ,Ha J,Kim SS

更新日期：2002-11-15 00:00:00

abstract：:Gastric inhibitory polypeptide (GIP) is released from the small intestine upon meal ingestion and increases insulin secretion from pancreatic β cells. Although the GIP receptor is known to be expressed in small intestine, the effects of GIP in small intestine are not fully understood. This study was designed to clarif...

journal_title：Biochemical and biophysical research communications

authors： Ogawa E,Hosokawa M,Harada N,Yamane S,Hamasaki A,Toyoda K,Fujimoto S,Fujita Y,Fukuda K,Tsukiyama K,Yamada Y,Seino Y,Inagaki N

更新日期：2011-01-07 00:00:00

abstract：:Extracellular signal-regulated kinase 1 and 2 (ERK1/2) have been implicated as important regulators of metabolic homeostasis. Here we generated a new mouse model with genetic deletion of two ERK1/2 phosphatases, dual specificity phosphatase (DUSP) 6 and 8, to further define the role of ERK1/2 in obesity development. D...

journal_title：Biochemical and biophysical research communications

authors： Liu R,Peters M,Urban N,Knowlton J,Napierala T,Gabrysiak J

更新日期：2020-11-26 00:00:00

abstract：:We have previously reported that the two components of R2TP complex, RNA polymerase II-associated protein 3 (RPAP3), and Reptin, regulate apoptosis. Here we characterize another component of the complex, PIH1 domain containing protein 1 (PIH1D1). PIH1D1 interacts with both RPAP3 and Monad in HEK293 or U2OS cells. PIH1...

journal_title：Biochemical and biophysical research communications

authors： Inoue M,Saeki M,Egusa H,Niwa H,Kamisaki Y

更新日期：2010-12-17 00:00:00

abstract：:The direct interaction of protein kinase C with the nucleus was examined utilizing endogenous protein phosphorylation and [3H]PDBu binding to detect the enzyme. Rat brain nuclei were relatively rich in phorbol ester receptors whereas liver nuclei contained less than 10% of their brain counterpart. Purified protein kin...

journal_title：Biochemical and biophysical research communications

authors： Misra UK,Sahyoun N

更新日期：1987-06-15 00:00:00

abstract：:Cyclosporine A (CSA) is a widely used immunosuppressant drug known to commonly cause cardio and nephrotoxicity. A study looking at the sex specificity of the cardiotoxicity of CSA revealed that sexual dimorphism existed when looking at the electrocardiographs and left ventricles of CSA-treated rats. We hypothesized th...

journal_title：Biochemical and biophysical research communications

authors： El-Bassossy HM,Eid BG

更新日期：2018-01-01 00:00:00

abstract：:2-Hydroxy-5-nitrobenzyl bromide, a highly reactive reagent towards tryptophan residues in proteins, is shown to activate the passive proton flux through the inner mitochondrial membrane of bovine heart submitochondrial particles (ETPH). When added at low concentrations, the reagent increased both the ATPase activity o...

journal_title：Biochemical and biophysical research communications

authors： Solaini G,Baracca A,Parenti Castelli G,Rossi CA

更新日期：1988-08-30 00:00:00

abstract：:The microbial degradative characteristics of butyl benzyl phthalate (BBP) were investigated by the Gordonia sp. strain MTCC 4818 isolated from creosote-contaminated soil. The test organism can utilize a number of phthalate esters as sole sources of carbon and energy, where BBP was totally degraded within 4 days under ...

journal_title：Biochemical and biophysical research communications

authors： Chatterjee S,Dutta TK

更新日期：2003-09-12 00:00:00

abstract：:Leucine-rich repeat kinase 2 (LRRK2) is the causal molecule of familial Parkinson's disease (PD), but its true physiological function remains unknown. In the normal mouse, LRRK2 is expressed in kidney, spleen, and lung at much higher levels than in brain, suggesting that LRRK2 may play an important role in these organ...

journal_title：Biochemical and biophysical research communications

authors： Maekawa T,Kubo M,Yokoyama I,Ohta E,Obata F

更新日期：2010-02-12 00:00:00

abstract：:2-Amino-3,8-dimethylimidazo(4,5-f)quinoxaline (MeIQx) is a potent mutagen found in cooked food. MeIQx and its isotopically labelled (13C, 15N2 and 14C) analogues were synthesised and used for metabolic studies in vivo. An equimolar mixture of MeIQx and its 13C, 15N2 stable isotope labelled analogue (containing tracer ...

journal_title：Biochemical and biophysical research communications

authors： Gooderham NJ,Watson D,Rice JC,Murray S,Taylor GW,Davies DS

更新日期：1987-11-13 00:00:00

abstract：:It is found that secretion of pancreastatin and somatostatin from QGP-1N cells is regulated through muscarinic receptor-mediated activation of phosphatidylinositide hydrolysis system. In this report, whether the cAMP pathway interacts with the phosphoinositide turnover system for the secretion of pancreastatin and som...

journal_title：Biochemical and biophysical research communications

authors： Tateishi K,Funakoshi A,Kitayama N,Matsuoka Y

更新日期：1992-06-30 00:00:00

abstract：:A protein designated mungin, isolated from mung bean (Phaseolus mungo) seeds, possessed activity against the fungi Rhizoctonia solani, Coprinus comatus, Mycosphaerella arachidicola, Botrytis cinerea, and Fusarium oxysporum. The 18-kDa protein also possessed a novel N-terminal sequence with similarity to cyclophilins. ...

journal_title：Biochemical and biophysical research communications

authors： Ye XY,Ng TB

更新日期：2000-07-14 00:00:00

abstract：:2-keto-3-deoxy-6-phosphogluconate aldolase (E.C. 4.1.2.14) has been purified in two chromatographic steps to 99% purity in 73% overall yield from Azotobacter vinelandii. The pure enzyme is a 70 kD trimeric Class I aldolase, inhibitable by bromopyruvate or pyruvate plus sodium borohydride, with a specific activity of 6...

journal_title：Biochemical and biophysical research communications

authors： Taha TS,Deits TL

更新日期：1994-04-15 00:00:00

abstract：:In order to examine the ability of an O-glycosylated serine residue preceding proline to stabilize a cis amide conformation in a fashion similar to that observed with aromatic amino acid residues, we prepared a series of glycosylated analogs of a small linear peptide which we have previous reported to contain a cis co...

journal_title：Biochemical and biophysical research communications

authors： Pao YL,Wormarld MR,Dwek RA,Lellouch AC

更新日期：1996-02-06 00:00:00

abstract：:3q21q26 syndrome, an acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS) with chromosomal translocations or inversions between the bands 3q21 and 3q26, is frequently associated with dysmegakaryocytopoiesis and increased platelet counts at the initial diagnosis. Since the EVI1 gene at 3q26 is transcriptional...

journal_title：Biochemical and biophysical research communications

authors： Shimizu S,Nagasawa T,Katoh O,Komatsu N,Yokota J,Morishita K

更新日期：2002-04-05 00:00:00

abstract：:Kurtoxin, a 63-amino acid peptide stabilized by four disulfide bonds, is the first reported peptide inhibitor of T-type voltage-gated calcium channels. Although T-type calcium channels have been implicated in a number of disease states, including epilepsy, chronic pain, hypertension and cancer, the lack of selective i...

journal_title：Biochemical and biophysical research communications

authors： Lee CW,Eu YJ,Min HJ,Cho EM,Lee JH,Kim HH,Nah SY,Swartz KJ,Kim JI

更新日期：2011-12-16 00:00:00

abstract：:Xenopus XmN-cadherin gene appears to have dual functions, since its mRNA is maternally provided in unfertilized eggs, once disappears almost completely during gastrula stage, then accumulates again specifically in neural tissues in later stage embryos. In the present experiment, we first followed the change in XmN-cad...

journal_title：Biochemical and biophysical research communications

authors： Hojyo T,Tooi O,Tashiro K,Shiokawa K

更新日期：1998-01-06 00:00:00

abstract：:In order to understand the molecular basis for antiprogestin action, we have compared the interaction of the antiprogestin [3H]RU38, 486 (RU486) and the progestin [3H]R5020 with the progesterone receptor (PR). In both MCF-7 and T47D human breast cancer cells, we have observed marked differences in the sedimentation pr...

journal_title：Biochemical and biophysical research communications

authors： Mullick A,Katzenellenbogen BS

更新日期：1986-02-26 00:00:00