Abstract：
:Using gold-labelled somatostatin, somatostatin binding sites were predominantly found in laminae I-III, X and on motorneurones of the rat lumbar spinal cord. A comparison with immunohistochemical staining using antisera against somatostatin receptor sequences revealed that the marked binding in laminae I-III coincided with the presence of somatostatin receptor-like immunoreactivity for the receptor subtypes 1, 2 and 3. Binding sites on motorneurones were only paralleled by an immunoreaction for subtype 3. In lamina X, however, the lack of a positive immunoreaction indicates that in this part other subtypes may be present.
journal_name
Brain Resjournal_title
Brain researchauthors
Segond von Banchet G,Schindler M,Hervieu GJ,Beckmann B,Emson PC,Heppelmann Bdoi
10.1016/s0006-8993(98)01226-8subject
Has Abstractpub_date
1999-01-16 00:00:00pages
254-7issue
1eissn
0006-8993issn
1872-6240pii
S0006-8993(98)01226-8journal_volume
816pub_type
杂志文章相关文献
BRAIN RESEARCH文献大全abstract：:The effect of hippocampal kindling on neuronal and glial marker proteins was studied in the rat by immunochemical methods. In hippocampus, pyriform cortex and amygdala there was an increase in glial fibrillary acidic protein (GFAP), indicating reactive gliosis, and an increase in the glycolytic enzyme NSE, suggesting ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(90)90791-9
更新日期：1990-10-29 00:00:00
abstract：:This study has assessed the neuroprotective efficacy of five AP-1 inhibitory peptides in an in vitro excitotoxicity model. The five AP-1 inhibitory peptides and controls of the JNK inhibitor peptide (JNKI-1D-TAT) and TAT cell-penetrating-peptide were administered to primary cortical neuronal cultures prior to kainic a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.09.007
更新日期：2010-11-11 00:00:00
abstract：:The healthy maturation of the brain is one of the intriguing topics that need to be investigated to understand human brain and child development. The present study aimed to investigate the development of memory processes both for auditory and visual memory using electroencephalography (EEG)-Brain Dynamics methodologie...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2020.147042
更新日期：2020-11-15 00:00:00
abstract：:In a study of the capacity of neural grafts to promote functional recovery in rats with fimbria-fornix lesions, 5 groups of rats were studied behaviourally and with acetylcholinesterase (AChE) histochemistry: (1) sham-operated controls; (2) bilateral fimbria-fornix lesions; (3) bilateral lesions plus bilateral solid e...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(82)90751-x
更新日期：1982-11-18 00:00:00
abstract：:We tested the hypothesis that intravenous infusion of human marrow stromal cells (hMSC) with a nitric oxide donor, (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl) aminio] diazen-1-ium-1,2-diolate (DETA/NONOate), enhances angiogenesis, neurogenesis and neurological functional recovery after stroke in rats compared to indivi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2003.11.080
更新日期：2004-04-16 00:00:00
abstract：:Work with ion-selective microelectrodes on the retina of the honeybee drone has shown that potassium is released from photoreceptors during activity and enters glial cells. Measurements of the extracellular voltage gradients indicate that, in this preparation, currents flowing through the glial cells in the 'spatial b...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90169-4
更新日期：1981-03-30 00:00:00
abstract：:The triggering of ectopic action potentials (APs) at axon terminals in a chronic epileptic cobalt focus was investigated in thalamocortical (TC) neurons of rats under urethane anesthesia. TC cells which were in register with an active epileptic aggregate discharged bursts of 2-11 APs. According to the rules of the col...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90628-m
更新日期：1992-03-27 00:00:00
abstract：:A gentle long-lasting handling produces persistent neurochemical and behavioural changes and attenuates the impairment in the behavioural reactivity to novelty induced by the prenatal exposure to diazepam (DZ) in adult male rat progeny. This study investigated the consequences of a late prenatal treatment with three G...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)03282-1
更新日期：2002-10-25 00:00:00
abstract：:Antagonism of the alpha receptor sub-type at gamma-aminobutyric acid (GABA) recognition sites in developing pigs was evaluated using the GABAA receptor antagonist bicuculline. The effect of bicuculline infusions was to produce an increase of phrenic and hypoglossal discharge amplitudes. This bicuculline-induced effect...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90222-4
更新日期：1994-07-04 00:00:00
abstract：:To gain greater insight on the molecular mechanisms that underlie ischemic stroke, we compared gene expression profiles in transient (tMCAO) and permanent middle cerebral artery occlusion (pMCAO) stroke models using Expression Analysis Systematic Explorer (EASE) pathway analysis software. Many transcripts were induced...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2005.11.090
更新日期：2006-02-03 00:00:00
abstract：:Damage to the medial temporal lobe (MTL) and diencephalon results in impaired long-term memory, which relies on the binding of multiple, mostly contextual, features. Recent neuroimaging and patient studies have suggested that impairments may also be present in working memory after MTL or diencephalic damage. To examin...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2007.07.066
更新日期：2007-10-03 00:00:00
abstract：:Increases in extracellular potassium concentrations reliably increase burst rates in cultured fetal murine spinal cord networks. This effect could be mimicked by either blocking voltage-gated potassium conductances or facilitating excitatory synaptic interactions, but not by blocking specific calcium-dependent potassi...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(94)90039-6
更新日期：1994-04-18 00:00:00
abstract：:Neuromuscular patterns associated with the development of hindlimb stepping behaviors were studied from birth to postnatal day 60 in normal kittens. Hindlimb muscles were chronically implanted with EMG electrodes at birth to characterize interlimb coordination and intralimb synergies during development of overground a...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0165-3806(88)90084-3
更新日期：1988-01-01 00:00:00
abstract：:Cytochrome P45011B1 (11 beta-hydroxylase) was detected in the brain of male rats by in situ hybridization methods. Normal Sprague-Dawley rats were compared to the transgenic strain TGR(mRen2)27, characterized by the expression of the murine Ren-2d renin gene and the development of severe hypertension. Specific ribopro...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(96)00540-9
更新日期：1996-09-09 00:00:00
abstract：:The mechanism(s) underlying age-associated diminutions in the rat striatal D2 dopamine receptor (D2-receptor) number was investigated. The levels of D2-receptor mRNA in 4-, 12- and 18-month-old rat striata were found not to change. In contrast, the levels of 110 kDa protein, labeled with a D2-receptor specific antibod...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(92)90095-q
更新日期：1992-03-20 00:00:00
abstract：:Altered dopamine regulation in the medial prefrontal cortex has been linked to drug abuse and disorders such as schizophrenia. Heterogeneous expression of the dopamine transporter, as well as the ability of the norepinephrine transporter to clear dopamine in the prefrontal cortex, delineates two potential sites for th...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(02)02542-8
更新日期：2002-05-17 00:00:00
abstract：:Results from the application of a procedure that allows simultaneous estimation of the rates of glucose transport from blood and of glucose phosphorylation in discrete regions of the brain are given for groups of rats displaying chemically induced motor disturbances. The procedure is based on sequential injections of ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(81)90782-4
更新日期：1981-09-28 00:00:00
abstract：:Kindling of the amygdaloid complex in rats results in an enhanced emotionality frequently expressed by an elevated anxiety and defensive attitude toward other animals. Defensive attitude may have important consequences in social context and if tested in a large space it may eventually lead to social withdrawal. To tes...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(01)03162-6
更新日期：2001-12-13 00:00:00
abstract：:A major role of tooth receptors in signaling overt or impending tissue damage (nociception) has been previously established by substantial evidence from mechanical, thermal and chemical stimulation of exposed dentin. We report evidence showing that some intradental receptors in canine teeth of the cat detect mechanica...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(85)90239-2
更新日期：1985-05-20 00:00:00
abstract：:Conditions for the stimulation of taurine release by illumination or increased K+ concentrations were established. The effect of Mg2+, ruthenium red and verapamil on taurine release induced by both procedures was compared. All these agents antagonize Ca2+-dependent release of neurotransmitters. Illumination-induced re...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(76)90054-8
更新日期：1976-09-03 00:00:00
abstract：:The effects of norepinephrine (NE) on inhibitory synaptic potentials were studied on CA1 pyramidal neurons in the hippocampal slice in vitro. Norepinephrine caused the appearance of multiple population spikes in the CA1 region of the hippocampal slice, reminiscent of the actions of gamma-aminobutyric acid (GABA) antag...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)91440-0
更新日期：1988-02-23 00:00:00
abstract：:Cerebral amyloid angiopathy (CAA) might disturb the sensitive mechanism of cerebral pressure autoregulation. This study examines whether dynamic cerebral autoregulation (CA) is impaired in the posterior or anterior circulation of CAA patients. Fifteen patients with known CAA on magnetic resonance imaging (MRI) and 14 ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.04.014
更新日期：2019-08-15 00:00:00
abstract：:Microspectrofluorimetric measurements of excitatory amino acid-evoked rises in intracellular free calcium concentration ([Ca2+]i), electrophysiological measurements of currents through single NMDA receptor-operated ion channels and estimates of cellular viability following NMDA challenge were employed to examine the i...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(95)00771-h
更新日期：1995-11-06 00:00:00
abstract：:Aluminum (Al) is among the most abundant elements on earth, it has been associated with the etiology of Alzheimer's disease. In the present study, AlCl(3) was administered with the dose of 10, 50 or 300 mg/kg b.wt/day through diet for 100 days. On day 101, overnight-fasted animals were sacrificed, the whole brains wer...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2010.02.024
更新日期：2010-04-09 00:00:00
abstract：:The effects of partial metabolic inhibition (induced by 2 h exposure to low concentrations of cyanide (NaCN)) on the glutamate receptor agonist alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA)-induced excitotoxicity and elevation of free cytoplasmic Ca2+ levels ([Ca2+]i) were studied in glucose-deprived pri...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(97)01123-2
更新日期：1998-01-01 00:00:00
abstract：:A chronic diet of ethanol has detrimental effects on the cholinergic system in adult humans and rats. This study examined the effects of chronic exposure to dietary ethanol on the anatomical organization of true acetylcholinesterase (AChE) active elements in rat cerebral cortex. We focused on the somatosensory cortex ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(93)90753-a
更新日期：1993-11-05 00:00:00
abstract：:There are sex differences in the neurochemistry of brainstem nuclei that participate in the control of breathing as well as sex differences in respiratory responses to hypoxia. Central chemoreception refers to the detection within the brain of minute changes in carbon dioxide (CO(2)) levels and the subsequent modulati...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2009.11.037
更新日期：2010-01-22 00:00:00
abstract：:Perfusion of the microcirculation after stroke is central to preserving neuronal function and improving functional outcome. Using laser scanning confocal microscopy (LSCM) and a novel computer software program, MIRAGE, we measured a reduction in cerebral microvessel diameter after 1 and 4 h of embolic middle cerebral ...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/s0006-8993(00)02543-9
更新日期：2000-09-08 00:00:00
abstract：:Nesfatin-1, an 82-amino acid peptide encoded by the secreted precursor nucleobinin-2 (NUCB2), exerts potent anorexigenic action independently of leptin signaling. This propensity has propelled this peptide and its analogues as potential anti-obesity drug candidates. However, a more extensive comprehension of its biolo...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/j.brainres.2019.01.032
更新日期：2019-05-15 00:00:00
abstract：:Using a specific antibody against each of the 4 catecholamine-synthesizing enzymes, dopamine or serotonin, we compared the localization of these substances in rat and mouse spinal cord with two kinds of fixative, such as paraformaldehyde and glutaraldehyde, and two types of sectioning technique, i.e. cryostat and micr...
journal_title：Brain research
pub_type： 杂志文章
doi：10.1016/0006-8993(88)90202-8
更新日期：1988-12-13 00:00:00
