The specificity of split renal membranes in hereditary nephritis.

abstract：:We report a case of fatal fibrosing peritonitis in a 28-year-old drug abuser. The extensive fibrosis, which was limited to the abdominal cavity, contained birefringent material. Silica was identified by spectrophotometric analysis. Silica is a component of talc (magnesium silicate) used as a drug filler. Relatively sm...

journal_title：Archives of pathology & laboratory medicine

authors： Castelli MJ,Armin AR,Husain A,Orfei E

更新日期：1985-08-01 00:00:00

abstract：:Carcinoembryonic antigen (CEA) is recommended as a serologic marker to monitor colorectal carcinoma recurrence. Elevations of CEA due to causes other than carcinoma exist and may lead to a misdiagnosis of recurrent carcinoma. We report a case of bowel sequestration with mucocele formation at the site of previous colo-...

journal_title：Archives of pathology & laboratory medicine

authors： Haber MM,Leon ME,Bakker JE,Nagle D

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Bcl-2 and p53 genes may participate in a common pathway for regulation of apoptosis. The aims of this study were (1) to study the immunohistochemical expression of the bcl-2 oncoprotein in colorectal tumors, (2) to correlate it with that of p53 protein overexpression, and (3) to compare it with histopathologi...

journal_title：Archives of pathology & laboratory medicine

authors： Mosnier JF,Perret AG,Vindimian M,Dumollard JM,Balique JG,Perpoint B,Boucheron S

更新日期：1996-07-01 00:00:00

abstract：:Pathologists' advocacy plays a central role in the establishment of continuously improving patient care quality and patient safety, and in the maintenance and progress of pathology as a profession. Pathology advocacy's primary goal is the betterment of patient safety and quality medical care; however, payment is a nec...

journal_title：Archives of pathology & laboratory medicine

authors： Allen TC

更新日期：2017-07-01 00:00:00

abstract：:As transfusion medicine becomes more complex, cooperative strategies are gaining increasing importance in relaying information to the treating physician and in incorporating the treating physician into the education and quality control processes. The broad domain of transfusion medicine is illustrated by the variety o...

journal_title：Archives of pathology & laboratory medicine

authors： Alving B,Alcorn K

更新日期：1999-06-01 00:00:00

abstract：CONTEXT:The Mre11-Rad50-NBS1 complex plays an important role in telomere maintenance. Recently, it has been proposed that alterations in Mre11 function may be contributing factors in the development of some tumors. Moreover, mutations of Mre11 have been demonstrated to cause reduced Mre11 immunostaining. OBJECTIVE:To ...

journal_title：Archives of pathology & laboratory medicine

authors： Nakanishi K,Kumaki F,Hiroi S,Mukai M,Ikeda E,Kawai T

更新日期：2006-09-01 00:00:00

abstract：:We report findings from an autopsy of a 45-year-old woman with the rare lysosomal storage disease mucolipidosis type III α/β. Her disease manifested most notably as multiple bone and cartilage problems with tracheal and bronchial malacia. Principal autopsy findings included gross abnormalities in bone and cartilage wi...

journal_title：Archives of pathology & laboratory medicine

authors： Kerr DA,Memoli VA,Cathey SS,Harris BT

更新日期：2011-04-01 00:00:00

abstract：:A peroxidase--antiperoxidase technique for S100 protein has been applied to 122 breast lesions from 122 patients. These included 35 cases of fibrocystic disease, 16 cases of sclerosing adenosis, 24 cases of papilloma and papillomatosis, 43 intraduct carcinomas, and four intralobular carcinomas. In fibrocystic disease,...

journal_title：Archives of pathology & laboratory medicine

authors： Egan MJ,Newman J,Crocker J,Collard M

更新日期：1987-01-01 00:00:00

abstract：:Accurate diagnosis of salivary gland tumors can be challenging because of the many diagnostic entities, the sometimes extensive morphologic overlap, and the rarity of most tumor types. Ancillary testing is beginning to ameliorate some of these challenges through access to newer immunohistochemical stains and fluoresce...

journal_title：Archives of pathology & laboratory medicine

authors： Griffith CC,Schmitt AC,Little JL,Magliocca KR

更新日期：2017-03-01 00:00:00

abstract：CONTEXT:Micropapillary urothelial carcinoma (MPUC) is a known aggressive variant of urothelial carcinoma. However, the reasons for its aggressiveness remain unclear. OBJECTIVE:To investigate the frequency of lymphovascular invasion in 22 cases of MPUC. DESIGN:Consecutive tissue sections were stained with D2-40 and CD...

journal_title：Archives of pathology & laboratory medicine

authors： McQuitty E,Ro JY,Truong LD,Shen SS,Zhai Q,Ayala AG

更新日期：2012-06-01 00:00:00

abstract：:This report describes a case of acute myeloid leukemia (subtype M1) with biphasic morphology. The bone marrow biopsy showed 2 distinct regions of blasts, one containing large cells and the other small cells. Morphometric and DNA ploidy analysis showed that the mean nuclear area and mean DNA index for the large cell re...

journal_title：Archives of pathology & laboratory medicine

authors： Imkie M,Davis MK,Persons DL,Cunningham MT

更新日期：2004-04-01 00:00:00

abstract：CONTEXT.—:The College of American Pathologists guidelines recommend testing additional tumor foci in multifocal invasive breast carcinomas for the biomarkers estrogen receptor (ER), progesterone receptor, and HER2 only if the carcinomas show different morphologies or grades. OBJECTIVE.—:To assess clinical significance...

journal_title：Archives of pathology & laboratory medicine

authors： Navale P,Bleiweiss IJ,Jaffer S,Nayak A

更新日期：2019-02-01 00:00:00

abstract：:We report the case of a 73-year-old man who presented with a 2- to 3-month history of epigastric discomfort and guaiac-positive stool. An upper gastrointestinal endoscopy revealed a diffuse erythematous nodular mucosa and submucosal thickening in the stomach. Diffuse mucosal nodularity was also found in the second por...

journal_title：Archives of pathology & laboratory medicine

authors： Tang Z,Jing W,Lindeman N,Harris NL,Ferry JA

更新日期：2004-09-01 00:00:00

abstract：:Adult rhabdomyoma is a benign, highly differentiated tumor of skeletal muscle. We observed transverse tubules and triads beside myofilaments in a rhabdomyoma from the submandibular area of a 66-year-old woman. Several types of muscle cells were present. In one, mitochondria abounded; in another, muscle filaments predo...

journal_title：Archives of pathology & laboratory medicine

authors： Warner TF,Goell W,Sundharadas M,Falk VS

更新日期：1981-11-01 00:00:00

abstract：CONTEXT:Case reports have described detection of candidemia by examination of peripheral blood smears. It is unclear whether this method has wider applicability for early detection of fungemia. OBJECTIVE:To determine the sensitivity of smear review for detecting candidemia. DESIGN:Normal and cytopenic blood was spike...

journal_title：Archives of pathology & laboratory medicine

authors： Branda JA,Ferraro MJ,Kratz A

更新日期：2007-01-01 00:00:00

abstract：:Basal cell carcinoma arising from the nipple of the breast is an uncommon malignancy, with only a handful of cases reported in the literature. The diagnosis is, however, important because basal cell carcinoma in this location can mimic breast cancer, may behave aggressively, and there is a relative lack of consensus i...

journal_title：Archives of pathology & laboratory medicine

authors： Gupta C,Sheth D,Snower DP

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To determine the frequency of mutation and overexpression of the p53 tumor suppressor gene in human soft tissue sarcomas. DESIGN:A total of 31 soft tissue sarcomas were analyzed by immunohistochemistry for the expression of p53 protein and were subsequently investigated by the polymerase chain reaction techn...

journal_title：Archives of pathology & laboratory medicine

authors： Yoo J,Lee HK,Kang CS,Park WS,Lee JY,Shim SI

更新日期：1997-04-01 00:00:00

abstract：:Accurate assessment of tissues for hematolymphoid neoplasms requires an integrated multiparameter approach. Although morphologic examination by light microscopy remains the mainstay of initial assessment for hematolymphoid neoplasms, immunophenotypic analysis by immunohistochemistry and/or flow cytometry is essential ...

journal_title：Archives of pathology & laboratory medicine

authors： Li S,Jaye DL,Bradley KT,Zhang L,Saxe D,Deeb G,Hill CE,Mann KP

更新日期：2017-03-01 00:00:00

abstract：:We studied a case of Sturge-Weber syndrome in a 66-year-old woman, who displayed associated angiomas of the thyroid gland and choroid plexi and leptomeningeal melanosis. These findings are discussed in light of the proposed pathogenesis of the syndrome and its relationship to the other neuroectodermal dysplasias. ...

journal_title：Archives of pathology & laboratory medicine

authors： Bentz MS,Towfighi J,Greenwood S,Zaino R

更新日期：1982-02-01 00:00:00

abstract：OBJECTIVES:To identify resources and summarize important issues in anatomic and clinical pathology training and to assist the pathology resident candidate in evaluating potential training programs. DATA SOURCES:Published guides for medical residency applicants, recent literature discussing pathology education, and Wor...

journal_title：Archives of pathology & laboratory medicine

authors： Yorke RF

更新日期：2000-06-01 00:00:00

abstract：CONTEXT:The inhibition of oncogenic kinase signaling is a successful strategy to treat both hematologic and solid malignancies. Patients with chronic myelogenous leukemia, lung adenocarcinoma, renal cell carcinoma, and gastrointestinal stromal tumors are experiencing tremendous clinical benefits from targeted therapies...

journal_title：Archives of pathology & laboratory medicine

authors： Marrari A,Wagner AJ,Hornick JL

更新日期：2012-05-01 00:00:00

abstract：:We describe a 14-year-old boy with a solitary cavernous hemangioma in the proximal small intestine that caused recalcitrant iron deficiency anemia beginning at 3 years of age. After a number of attempts to ascertain the cause of the anemia were unsuccessful, the vascular tumor was ultimately diagnosed in the jejunum, ...

journal_title：Archives of pathology & laboratory medicine

authors： Boyle L,Lack EE

更新日期：1993-09-01 00:00:00

abstract：:Atherosclerosis can be defined as a disease process that occurs when the influx and deposition of cholesterol into the arterial wall exceed the egress of cholesterol from the arterial wall. This process is characterized by early deposition of cholesterol in and around arterial wall cells. The cholesterol is derived fr...

journal_title：Archives of pathology & laboratory medicine

authors： Mahley RW

更新日期：1983-08-01 00:00:00

abstract：CONTEXT:Genomic medicine is revolutionizing patient care. Physicians in areas as diverse as oncology, obstetrics, and infectious disease have begun using next-generation sequencing assays as standard diagnostic tools. OBJECTIVE:To review the role of pathologists in genomic testing as well as current educational progra...

journal_title：Archives of pathology & laboratory medicine

authors： Haspel RL,Olsen RJ,Berry A,Hill CE,Pfeifer JD,Schrijver I,Kaul KL

更新日期：2014-04-01 00:00:00

abstract：CONTEXT:In immunohistochemistry, nonstandardized antigen retrieval protocols and fluids, poor-quality antibodies, and the presence of endogenous biotin frequently lead to incorrect results. Recently, advanced reagents including bifunctional SkipDewax pretreatment solution (BSPS), rabbit monoclonal (RM) antibodies, and ...

journal_title：Archives of pathology & laboratory medicine

authors： Wong SC,Chan JK,Lo ES,Chan AK,Wong MC,Chan CM,Lam MY,Chan AT

更新日期：2007-07-01 00:00:00

abstract：CONTEXT:The College of American Pathologists (CAP) Human Papillomavirus (High-Risk) Survey for Cytopathology and Other Laboratories (CHPV) meets the Clinical Laboratory Improvement Amendments of 1988 (CLIA '88) requirements for 5 proficiency testing challenges analyzed 3 times per year. This study reports laboratory pe...

journal_title：Archives of pathology & laboratory medicine

authors： Moriarty AT,Bentz JS,Winkler B,Fischer AH,Laucirica R,Souers RJ,Thomas N,Zhao C

更新日期：2013-05-01 00:00:00

abstract：CONTEXT:The advent of new endoscopic optical techniques is likely to change pathologists' role in diagnosis. OBJECTIVE:To describe how confocal laser endomicroscopy (CLE) works, show its advantages and limitations compared to cytohistologic biopsy, and explore how it may affect the practice of pathology. DATA SOURCES...

journal_title：Archives of pathology & laboratory medicine

authors： Paull PE,Hyatt BJ,Wassef W,Fischer AH

更新日期：2011-10-01 00:00:00

abstract：CONTEXT:-Evaluation of 12 or more lymph nodes (LNs) is currently used as a quality indicator for adequacy of pathologic examination of colon cancer resections. OBJECTIVE:-To evaluate the utility of a focused LN search in the immediate vicinity of the tumor and a "second look" protocol in improving LN staging in colon ...

journal_title：Archives of pathology & laboratory medicine

authors： Lisovsky M,Schutz SN,Drage MG,Liu X,Suriawinata AA,Srivastava A

更新日期：2017-01-01 00:00:00

abstract：:Alveolar proteinosis (AP) and postobstructive or endogenous lipid pneumonia (ELP) are two distinct morphologic types of phospholipid accumulation in the lung. In ELP, ultrastructurally amorphous fat accumulates in the cytoplasm of alveolar macrophages. In AP, lamellar surfactant bodies with an electron microscopic com...

journal_title：Archives of pathology & laboratory medicine

authors： Verbeken EK,Demedts M,Vanwing J,Deneffe G,Lauweryns JM

更新日期：1989-08-01 00:00:00

abstract：:Perfluorochemicals have been shown to have a high affinity for oxygen and therefore, have potential use in circumstances in which conventional blood transfusions are not possible. We examined by light and electron microscopy (EM) histologic changes in liver, spleen, lung, and kidney of rabbits each infused with 20 to ...

journal_title：Archives of pathology & laboratory medicine

authors： Nanney L,Fink LM,Virmani R

更新日期：1984-08-01 00:00:00