Carcinoembryonic antigen elevation due to bowel sequestration with mucocele formation following colonic resection.

Abstract:

:Carcinoembryonic antigen (CEA) is recommended as a serologic marker to monitor colorectal carcinoma recurrence. Elevations of CEA due to causes other than carcinoma exist and may lead to a misdiagnosis of recurrent carcinoma. We report a case of bowel sequestration with mucocele formation at the site of previous colo-colic anastomosis causing a mild elevation in CEA. The patient exhibited increasing CEA levels 6 years after resection of a sigmoid colon carcinoma with end-to-end anastomosis. Subsequently, computed tomographic and positron emission tomographic scans documented the presence of a cystic mass showing increased uptake at the anastomotic site. At exploratory laparotomy a mass lesion with mucus-filled protrusions was resected. Pathologic examination documented the presence of sequestration of a segment of the bowel wall with a mucocele and no overlying defect at the mucosal anastomotic site by demonstrating the presence of all bowel layers. After resection of the lesion, the CEA level normalized.

journal_name

Arch Pathol Lab Med

authors

Haber MM,Leon ME,Bakker JE,Nagle D

doi

10.1043/1543-2165(2003)127<1376:CAEDTB>2.0.CO;2

subject

Has Abstract

pub_date

2003-10-01 00:00:00

pages

1376-9

issue

10

eissn

0003-9985

issn

1543-2165

pii

CR3043

journal_volume

127

pub_type

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