Effect of apolipoprotein E status on clinical features of dementia.

abstract：OBJECTIVE:In order to study secular changes in personality factors neuroticism and extroversion, representative population samples of non-demented 75-year-olds underwent psychiatric examinations in 1976-1977 (total n = 223, 138 women, 85 men) and 2005-2006 (total n = 556, 322 women and 234 men). METHODS:Eysenck Person...

journal_title：International journal of geriatric psychiatry

authors： Billstedt E,Waern M,Duberstein P,Marlow T,Hellström T,Ostling S,Skoog I

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVES:Suicide in older adults is a major public health issue. Past research across the US adult population has linked prescription medication misuse with suicidal ideation. No work has evaluated associations between prescription opioid or benzodiazepine misuse and suicidal ideation in older adults, and this work a...

journal_title：International journal of geriatric psychiatry

authors： Schepis TS,Simoni-Wastila L,McCabe SE

更新日期：2019-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effect of cobalamin/folate supplementation on cognitive function in elderly patients with dementia. METHOD:The cobalamin/folate status of the patients was evaluated by measuring plasma homocysteine, serum methylmalonic acid, serum cobalamin and blood folate. Thirty-three patients were stu...

journal_title：International journal of geriatric psychiatry

authors： Nilsson K,Gustafson L,Hultberg B

更新日期：2001-06-01 00:00:00

abstract：OBJECTIVE:This study examined the association between a history of heavy alcohol use and smoking, presence of the apolipoprotein-E epsilon 4 allele (APOE epsilon4), and age of disease onset in a community dwelling sample of 685 Alzheimer's disease (AD) patients spanning three ethnic groups. DESIGN:Cross-sectional stud...

journal_title：International journal of geriatric psychiatry

authors： Harwood DG,Kalechstein A,Barker WW,Strauman S,St George-Hyslop P,Iglesias C,Loewenstein D,Duara R

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The burgeoning field of gerontechnology, which is the interdisciplinary field of applying technology to ageing issues, has focused primarily on "active ageing" and maintaining independence for older adults. To date, there has been less focus on people who develop dementia. Here, we argue for the field of ger...

journal_title：International journal of geriatric psychiatry

authors： Leroi I,Watanabe K,Hird N,Sugihara T

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Depression is common in Alzheimer's disease (AD; 5-35%). It is associated with increased disability, cost of care and carer burden. Exercise is known to be associated with a lower prevalence of depression across the age range but little is known about its relationship to depression in AD. AIMS:To investigat...

journal_title：International journal of geriatric psychiatry

authors： Regan C,Katona C,Walker Z,Livingston G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Proper screening of depression among older adults depends on accurate cut-off scores. Recent articles have recommended the Geriatric Depression Scale (GDS) and the Cornell Scale for Depression in Dementia (CSDD) for this screening. However, there has been no investigation of the sensitivity and specificity o...

journal_title：International journal of geriatric psychiatry

authors： Schreiner AS,Hayakawa H,Morimoto T,Kakuma T

更新日期：2003-06-01 00:00:00

abstract：OBJECTIVES:To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS:Adults with DS were recruited from community settings and followed up for ...

journal_title：International journal of geriatric psychiatry

authors： Prasher VP,Sajith SG,Mehta P,Zigman WB,Schupf N

更新日期：2010-02-01 00:00:00

abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

journal_title：International journal of geriatric psychiatry

authors： Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Depression and generalised anxiety disorder frequently overlap. The question remains unresolved whether these are specific disorders, or that they represent different dimensions of a single disorder. Although both are highly prevalent disorders in this age group, studies on this issue in the elderly are scar...

journal_title：International journal of geriatric psychiatry

authors： Schoevers RA,Beekman AT,Deeg DJ,Jonker C,van Tilburg W

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVES:To investigate the efficacy of the chronic usage of the cholinesterase inhibitor rivastigmine in patients with dementia in the prevention of delirium in case of hospitalisation. DESIGN:Retrospective cohort study. SETTING:Non-geriatric wards of an 1120 bed general teaching hospital in s-Hertogenbosch, The N...

journal_title：International journal of geriatric psychiatry

authors： Dautzenberg PL,Mulder LJ,Olde Rikkert MG,Wouters CJ,Loonen AJ

更新日期：2004-07-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of medication adherence to 12-month depression scores in the context of other psychosocial and clinical predictors of depression in a sample of older adults treated for depression. METHODS:Secondary analysis of a prospective cohort study involving 241 older patients undergoing dep...

journal_title：International journal of geriatric psychiatry

authors： Bosworth HB,Voils CI,Potter GG,Steffens DC

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...

journal_title：International journal of geriatric psychiatry

authors： Luckhaus C,Grass-Kapanke B,Blaeser I,Ihl R,Supprian T,Winterer G,Zielasek J,Brinkmeyer J

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Ischaemic vascular dementia shares risk factors with stroke. There is evidence that control of these risk factors may prevent or alter the course of vascular dementia. OBJECTIVE:To assess the effect of regular low-dose aspirin on outcomes for patients with vascular dementia. DESIGN:Retrospective analysis o...

journal_title：International journal of geriatric psychiatry

authors： Devine ME,Rands G

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related fact...

journal_title：International journal of geriatric psychiatry

authors： Shin HY,Kim SW,Kim JM,Shin IS,Yoon JS

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Parental death during childhood, and offspring and spouse death during adulthood have individually been associated with faster cognitive decline and higher Alzheimer's disease (AD) risk in late life. However, the cumulative effect of childhood and adulthood family deaths on AD risk among different age cohort...

journal_title：International journal of geriatric psychiatry

authors： Norton MC,Fauth E,Clark CJ,Hatch D,Greene D,Pfister R,Tschanz JT,Smith KR

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:The purpose of this study was to explore the effects of demographic variables on Stroop Color and Word Test (SCWT) performance in an educationally diverse elderly population and to provide normative information. METHODS:SCWT was administered to 564 community-dwelling volunteers aged 60-90 years with an educa...

journal_title：International journal of geriatric psychiatry

authors： Seo EH,Lee DY,Choo IH,Kim SG,Kim KW,Youn JC,Jhoo JH,Woo JI

更新日期：2008-10-01 00:00:00

abstract：AIM:This study looks at the objective and subjective characteristics of home respite service provision and its impact on the informal care burden of dependent elders. METHOD:A sample of 296 dependent people and their informal caregivers was randomly selected among users and non-users of the Home Help Service (HHS) in ...

journal_title：International journal of geriatric psychiatry

authors： Carretero S,Garcés J,Ródenas F

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:This study examined the moderating effect of caregiver burden on the relationship between the health status of Alzheimer's disease (AD) patients and their use of institutional services (i.e., hospitalization, nursing home, and residential care). METHODS:Data were obtained at baseline and at 3, 6, and 9 month...

journal_title：International journal of geriatric psychiatry

authors： Miller EA,Rosenheck RA,Schneider LS

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Beneficial effects of repetitive transcranial magnetic stimulation (rTMS) were demonstrated by many controlled studies in major depression. Moreover, this promising and non invasive therapeutic tool seems to be better tolerated than electroconvulsive therapy.Vascular depression is a subtype of late-life depr...

journal_title：International journal of geriatric psychiatry

authors： Fabre I,Galinowski A,Oppenheim C,Gallarda T,Meder JF,De Montigny C,Olié JP,Poirier MF

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Wandering represents a major problem in the management of patients with Alzheimer's disease (AD). In this study we examined the utility of the Algase Wandering Scale (AWS), a newly developed psychometric instrument that asks caregivers to assess the likelihood of wandering behavior. METHODS:The AWS was admi...

journal_title：International journal of geriatric psychiatry

authors： Marcus JF,Cellar JS,Ansari FP,Bliwise DL

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:We investigated cognitive dysfunction in patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) who present hemispheric asymmetries of cerebral metabolic rate of glucose (CMRglc) decrease on (18) F-fluorodeoxyglucose positron emission tomography. METHODS:Based on the hemispheric...

journal_title：International journal of geriatric psychiatry

authors： Murayama N,Ota K,Kasanuki K,Kondo D,Fujishiro H,Fukase Y,Tagaya H,Sato K,Iseki E

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:To examine whether psychogeriatric admissions increased after COVID-19, independent of seasonal variation; whether the increase was comparable with that seen in severe acute respiratory syndrome (SARS); and which factors were associated with such increase. METHODS:All psychiatric admissions aged 65 or older...

journal_title：International journal of geriatric psychiatry

authors： Lee ATC,Mo FYM,Lam LCW

更新日期：2020-09-06 00:00:00

abstract：RESEARCH OBJECTIVE:Estimates of the prevalence of major depression vary widely. Current estimates range from 2 to 14 % depending upon the definition and procedure for diagnosis. Further, most estimates are for special populations, either living in selected geographic areas or receiving specific types of medical care. A...

journal_title：International journal of geriatric psychiatry

authors： McCall NT,Parks P,Smith K,Pope G,Griggs M

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Vascular depression is an important conceptual and clinical concept. OBJECTIVE:To apply criteria which, in an ideal world, should be satisfied before an association between depression and vascular disease can be considered robust. METHOD:A literature review with discussion of findings in the light of recen...

journal_title：International journal of geriatric psychiatry

authors： Baldwin RC

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The mini-mental state exam (MMSE) has been used to address questions such as determination of appropriate cutoff scores for differentiation of individuals with intact cognitive function from patients with dementia and rate of cognitive decline. However, little is known about the relationship of performance i...

journal_title：International journal of geriatric psychiatry

authors： Guerrero-Berroa E,Luo X,Schmeidler J,Rapp MA,Dahlman K,Grossman HT,Haroutunian V,Beeri MS

更新日期：2009-12-01 00:00:00

abstract：AIM:To assess the effectiveness of reminiscence and life review on late-life depression across different target groups and treatment modalities. METHOD:Twenty controlled outcome studies were retrieved from Psychlit, Medline and Dissertation Abstracts. For each study a standardised effect size, d, was calculated and a ...

journal_title：International journal of geriatric psychiatry

authors： Bohlmeijer E,Smit F,Cuijpers P

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVES:To gain more insight into the association between severity of Alzheimer's Disease (AD) and prevalence of comborbid depression. METHODS:A systematic literature review based on the Cochrane methodology was performed. PubMed, PsychINFO and EMBASE databases were searched for existing studies that fulfilled pred...

journal_title：International journal of geriatric psychiatry

authors： Verkaik R,Nuyen J,Schellevis F,Francke A

更新日期：2007-11-01 00:00:00

abstract：OBJECTIVE:To measure depressive symptomatology in a largely illiterate elderly population in India, using a new Hindi version of the Geriatric Depression Scale (GDS-H), and to examine its distribution and associations with age, gender, literacy, cognitive impairment and functional impairment. DESIGN:A Hindi version of...

journal_title：International journal of geriatric psychiatry

authors： Ganguli M,Dube S,Johnston JM,Pandav R,Chandra V,Dodge HH

更新日期：1999-10-01 00:00:00