Cognitive dysfunction in patients with very mild Alzheimer's disease and amnestic mild cognitive impairment showing hemispheric asymmetries of hypometabolism on ¹⁸F-FDG PET.

abstract：OBJECTIVE:To determine the efficacy and tolerability of citalopram when compared to other antidepressants for late-life depression (LLD). METHODS:We searched electronic databases and trial registries to identify randomized controlled trials comparing citalopram to other antidepressants for LLD. Study quality was asses...

journal_title：International journal of geriatric psychiatry

authors： Seitz DP,Gill SS,Conn DK

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:There is a paucity of cross-cultural studies of behavioural and psychological symptoms of dementia (BPSD). METHOD:BPSD were examined in a consecutive series of Indian sub-continent origin and white indigenous elders admitted to a dementia day hospital using the BEHAVE-AD. The correlates of individual BPSD i...

journal_title：International journal of geriatric psychiatry

authors： Haider I,Shah A

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:To find a blood biomarker and disease-related peptides in Alzheimer's disease (AD), we comprehensively detected serum peptides. METHODS:Ion intensity of serum peptides from 62 AD patients and 82 control subjects was measured by mass spectrometry. RESULTS:A total of 157 peptides were detected from 30 AD pati...

journal_title：International journal of geriatric psychiatry

authors： Noguchi M,Sato T,Nagai K,Utagawa I,Suzuki I,Arito M,Iizuka N,Suematsu N,Okamoto K,Kato T,Yamaguchi N,Kurokawa MS

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:In recent years, there has been a blossoming of studies examining cerebrospinal fluid (CSF) as a method of studying the pathophysiology of delirium. We systematically reviewed the literature for CSF studies in delirium and provide here a summary of the implications for our understanding of delirium pathophysi...

journal_title：International journal of geriatric psychiatry

authors： Hall RJ,Watne LO,Cunningham E,Zetterberg H,Shenkin SD,Wyller TB,MacLullich AMJ

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:This study explored whether patients with late-onset major depressive disorder showed higher carotid artery intima-medium thickness (IMT) and investigated the relationship between the IMT and white matter hyperintensities on magnetic resonance imaging (MRI) among patients. METHODS:Fourteen elderly patients ...

journal_title：International journal of geriatric psychiatry

authors： Chen CS,Chen CC,Kuo YT,Chiang IC,Ko CH,Lin HF

更新日期：2006-01-01 00:00:00

abstract：OBJECTIVES:The pattern of neural damage in dementia with Lewy Bodies (DLB) led us to hypothesize that patients with DLB would be particularly impaired on parallel ('pop-out') search tasks, relative to serial search tasks, and that this would serve to distinguish DLB from other forms of neurodegenerative disease, partic...

journal_title：International journal of geriatric psychiatry

authors： Cormack F,Gray A,Ballard C,Tovée MJ

更新日期：2004-08-01 00:00:00

abstract：OBJECTIVE:This study aimed to: (i) replicate previous findings that women experience more strain and distress than men when caring for dementing spouses; (ii) explore what factors underlie this sex difference. DESIGN:Two closely matched subsamples of spouse carers, husbands and wives respectively, were selected and th...

journal_title：International journal of geriatric psychiatry

authors： Collins C,Jones R

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Dementia is a major public health problem. Increased attention is being paid to the quality of life (QOL) of people with this chronic disease. There have been no longitudinal studies of QOL change in dementia. METHOD:Longitudinal study of a cohort of 47 persons with dementia residing in a long-term care fac...

journal_title：International journal of geriatric psychiatry

authors： Lyketsos CG,Gonzales-Salvador T,Chin JJ,Baker A,Black B,Rabins P

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS:Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were as...

journal_title：International journal of geriatric psychiatry

authors： Koorevaar AML,Hegeman JM,Lamers F,Dhondt ADF,van der Mast RC,Stek ML,Comijs HC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the contribution of applying the theoretical framework of implementation science for adherence to non-pharmacological interventions to prevent delirium. METHODS:A quasi-experimental prospective design was conducted from March 2017 to October 2018 in a teaching hospital. Participants included 149 ...

journal_title：International journal of geriatric psychiatry

authors： Garrido MA,Alvarez EA,Ponce DP,Salech F,Tobar DI,Tobar EA

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To examine the effects of risperidone and olanzapine on cognitive functioning in elderly patients with schizophrenia or schizoaffective disorder. METHOD:One hundred seventy-six elderly inpatients and outpatients with schizophrenia or schizoaffective disorder were enrolled in this multicenter, double-blind tr...

journal_title：International journal of geriatric psychiatry

authors： Harvey PD,Napolitano JA,Mao L,Gharabawi G

更新日期：2003-09-01 00:00:00

abstract：:This review presents evidence of the undertreatment of pain for people with cognitive impairment and explores reasons for this, emphasizing inadequate detection due to lack of suitable pain assessment protocols. Implications for practice and suggestions for further research are made. ...

journal_title：International journal of geriatric psychiatry

authors： Cook AK,Niven CA,Downs MG

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVES:Physical symptoms are known to be associated with late life depression both cross-sectionally and over time. We attempted to determine if self-reported shortness of breath (SoB) is associated with depressive symptoms at long-term (3-year) follow-up in a community sample of older (65+) adults. METHODS:A samp...

journal_title：International journal of geriatric psychiatry

authors： Blazer DG,Hybels CF

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:To evaluate the association between the degree of integration in community mental health teams (CMHTs) and: (i) the costs of service provision; (ii) rates of mental health inpatient and care home admission. METHODS:An observational study of service use and admissions to institutional care was undertaken for...

journal_title：International journal of geriatric psychiatry

authors： Wilberforce M,Tucker S,Brand C,Abendstern M,Jasper R,Challis D

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) causes progressive loss of memory and disability, especially in older people. As worldwide population grows older, AD is responsible for an important social and economical burden in many nations. People suffering from AD may experience health-related stigma that influences their atti...

journal_title：International journal of geriatric psychiatry

authors： Piver LC,Nubukpo P,Faure A,Dumoitier N,Couratier P,Clément JP

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Mild cognitive impairment (MCI) is a clinical concept that categorizes subjects who are in an intermediate cognitive state between normal aging and dementia. The aim of this study is to characterize behavior in MCI compared with Alzheimer's disease (AD) and healthy older patients. DESIGN:A cross-sectional a...

journal_title：International journal of geriatric psychiatry

authors： Van der Mussele S,Le Bastard N,Vermeiren Y,Saerens J,Somers N,Mariën P,Goeman J,De Deyn PP,Engelborghs S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Despite modest efficacy, unpredictable individual utility, and a high rate of adverse effects, behavioural and psychological symptoms of dementia (BPSD) are common determinants for antipsychotic drug therapy in nursing home patients. AIMS:To explore the impact on BPSD of stopping long-term antipsychotic tre...

journal_title：International journal of geriatric psychiatry

authors： Ruths S,Straand J,Nygaard HA,Aarsland D

更新日期：2008-09-01 00:00:00

abstract：OBJECTIVES:To determine the prevalence of body image dysfunction in a cohort of older, inpatient women, and to examine any associated health or sociodemographic factors. METHODS:In this cross-sectional, observational study, 50 older women admitted to a subacute hospital completed the Body Shape Questionnaire (BSQ-34),...

journal_title：International journal of geriatric psychiatry

authors： Dean E,Haywood C,Hunter P,Austin N,Prendergast L

更新日期：2020-02-01 00:00:00

abstract：OBJECTIVES:The number of older adults with severe mental health problems such as schizophrenia is likely to double in the next 20 years. The needs of this patient group change across the life course, but difficulties with social functioning persist into older age. Poorer social functioning is associated with poorer out...

journal_title：International journal of geriatric psychiatry

authors： Smart EL,Brown L,Palmier-Claus J,Raphael J,Berry K

更新日期：2020-05-01 00:00:00

abstract：OBJECTIVES:The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers. METHODS:Fifty-six community-dwelling people with dementia (PWD) and knee ost...

journal_title：International journal of geriatric psychiatry

authors： Law W,Kwok TCY

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...

journal_title：International journal of geriatric psychiatry

authors： Xue H,Hou P,Li Y,Mao X,Wu L,Liu Y

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVES:Recent data suggests that statins have positive effects on cognition in older adults. Studies in patients with mood disorders have found contradicting positive and negative effects of statins on mood and cognition, with limited data in bipolar disorder (BD). The objective of this study was to assess the asso...

journal_title：International journal of geriatric psychiatry

authors： Rej S,Schulte SW,Rajji TK,Gildengers AG,Miranda D,Menon M,Butters MA,Mulsant BH

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVES:This integrative review aimed to synthesize studies that investigated the effects of acupressure on sleep quality, depression, anxiety, and agitation in older people, and to describe the acupressure procedures and techniques applied in the included studies. METHODS:A literature search was conducted using el...

journal_title：International journal of geriatric psychiatry

authors： Hmwe NTT,Browne G,Mollart L,Allanson V,Chan SW

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Dementia is under-diagnosed in primary care. This study investigated whether an in-home geriatric assessment and management programme could improve the identification of patients with dementia in primary care. METHODS:A secondary analysis was performed, using data of a randomised controlled trial ...

journal_title：International journal of geriatric psychiatry

authors： Perry M,Melis RJ,Teerenstra S,Drasković I,van Achterberg T,van Eijken MI,Lucassen P,Rikkert MG

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:Apathy is a prominent and disabling symptom in Parkinson's disease (PD) and is a multidimensional behaviour, but which dimensions are specifically affected is unclear. Therefore, the aim of this preliminary study was to determine the psychometric properties of the Dimensional Apathy Scale (DAS) and explore th...

journal_title：International journal of geriatric psychiatry

authors： Radakovic R,Davenport R,Starr JM,Abrahams S

更新日期：2018-01-01 00:00:00

abstract：OBJECTIVES:The present study assessed whether caregiving contextual factors moderated outcomes of a caregiver intervention. METHODS:Extant data from the Resources for Enhancing Alzheimer's Caregiver Health (REACH) II study, a randomized-control trial of a multi-component, multi-site intervention for dementia caregiver...

journal_title：International journal of geriatric psychiatry

authors： Hatch DJ,DeHart WB,Norton MC

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. METHODS/DESIGN:A population-based case-control study of a sample of 65 997 participants from the Survey of H...

journal_title：International journal of geriatric psychiatry

authors： Conde-Sala JL,Garre-Olmo J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...

journal_title：International journal of geriatric psychiatry

authors： Bour A,Rasquin S,Aben I,Strik J,Boreas A,Crijns H,Limburg M,Verhey F

更新日期：2009-10-01 00:00:00

abstract：INTRODUCTION:Dementia is a growing health and social concern for all Australians. Whilst the prevalence of dementia amongst Australia's indigenous people is unclear, there is some evidence that dementia rates are five times that of the general Australian population. To date no studies have examined dementia knowledge l...

journal_title：International journal of geriatric psychiatry

authors： Garvey G,Simmonds D,Clements V,O'Rourke P,Sullivan K,Gorman D,Curnow V,Wise S,Beattie E

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The cost-effectiveness of memantine for the treatment of moderate and severe Alzheimer's disease has been assessed in several European countries. Objective of the study was to assess it in Norwegian settings. METHODS:This cost-utility analysis used a Markov modelling approach to simulate the evolution of pa...

journal_title：International journal of geriatric psychiatry

authors： Rive B,Aarsland D,Grishchenko M,Cochran J,Lamure M,Toumi M

更新日期：2012-06-01 00:00:00