Apathy dimensions in Parkinson's disease.

Abstract:

OBJECTIVE:Apathy is a prominent and disabling symptom in Parkinson's disease (PD) and is a multidimensional behaviour, but which dimensions are specifically affected is unclear. Therefore, the aim of this preliminary study was to determine the psychometric properties of the Dimensional Apathy Scale (DAS) and explore the multidimensional profile of apathy in PD patients. METHODS:Thirty-four PD patients, with 30 of their informants/carers, and 34 healthy controls, with 30 of their informants, completed the DAS, Apathy Evaluation Scale and the Geriatric Depression Scale Short Form. Motor staging and independent living status were recorded. RESULTS:Comparative group analyses revealed that PD patients were significantly more apathetic on self-rated executive (p = 0.01) and initiation (p = 0.03) dimensions than controls, where only executive apathy was significantly higher in ratings of patients' informants/carers compared with controls' informants (p = 0.02). A third of patients were impaired on at least one apathy dimension. Additionally, patients with apathy tended to have more impaired activities of daily living, while none of the apathy dimensions related to motor disability. CONCLUSION:Our findings show the DAS is a valid and reliable multidimensional apathy tool for use in PD. PD is characterised by an executive apathy profile as determined by informants/carers, although patients described both executive and initiation apathy. This indicates a lack of motivation for planning, organisation and attention and lack of initiation of thoughts or behaviours. Further research is needed to determine the cognitive underpinnings of this emerging apathy profile and the clinical impact in PD. Copyright © 2017 John Wiley & Sons, Ltd.

authors

Radakovic R,Davenport R,Starr JM,Abrahams S

doi

10.1002/gps.4697

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

151-158

issue

1

eissn

0885-6230

issn

1099-1166

journal_volume

33

pub_type

杂志文章
  • Disassociation of verbal learning and hippocampal volume in type 2 diabetes and major depression.

    abstract:OBJECTIVE:The purpose of this study was to examine the relationship between verbal learning and memory performance and hippocampal volume in subjects with co-morbid type 2 diabetes and major depression compared with healthy control subjects and subjects with type 2 diabetes alone. METHODS:Twenty four subjects with typ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4149

    authors: Ajilore O,Lamar M,Medina J,Watari K,Elderkin-Thompson V,Kumar A

    更新日期:2015-04-01 00:00:00

  • Cognitive impairment in late life schizophrenia and bipolar I disorder.

    abstract:OBJECTIVE:Evidence in younger populations suggests quantitative but not categorical differences in cognitive impairments between schizophrenia and bipolar disorder. It is uncertain whether a similar distinction applies to patients in later life. METHODS:We compared the cognitive abilities of older, community-living sc...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.3793

    authors: Meesters PD,Schouws S,Stek M,de Haan L,Smit J,Eikelenboom P,Beekman A,Comijs H

    更新日期:2013-01-01 00:00:00

  • Cost effectiveness of using cognitive screening tests for detecting dementia and mild cognitive impairment in primary care.

    abstract:INTRODUCTION:We estimated the cost effectiveness of different cognitive screening tests for use by General Practitioners (GPs) to detect cognitive impairment in England. METHODS:A patient-level cost-effectiveness model was developed using a simulated cohort that represents the elderly population in England (65 years a...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4626

    authors: Tong T,Thokala P,McMillan B,Ghosh R,Brazier J

    更新日期:2017-12-01 00:00:00

  • Quality of life in dementia patients in long-term care.

    abstract:OBJECTIVE:To evaluate variables associated with quality of life (QOL) in dementia residents in a long-term care facility using a recently standardized and validated dementia-specific QOL scale (ADRQL). METHOD:A cross-sectional, case-control design was employed using validated scales to assess dementia-related symptoma...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-1166(200002)15:2<181::aid-gps96

    authors: González-Salvador T,Lyketsos CG,Baker A,Hovanec L,Roques C,Brandt J,Steele C

    更新日期:2000-02-01 00:00:00

  • Predictors of institutionalization of cognitively-impaired elderly cared for by their relatives.

    abstract:OBJECTIVES:The purpose of this study is to identify risk factors for nursing home placement of cognitively-impaired elderly, with special attention to the role of psychosocial factors such as the caregiver's preference for institutionalization and the quality of the dyadic relationship. METHODS:Partners, children and ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.484

    authors: Spruytte N,Van Audenhove C,Lammertyn F

    更新日期:2001-12-01 00:00:00

  • Impacts of a multicomponent intervention programme on neuropsychiatric symptoms in people with dementia and psychological health of caregivers: A feasibility pilot study.

    abstract:OBJECTIVES:The objectives of this study are to explore the feasibility of a multicomponent intervention programme and to evaluate its impacts on behavioural and psychological symptoms of dementia (BPSD) and psychological health of caregivers. METHODS:Fifty-six community-dwelling people with dementia (PWD) and knee ost...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5191

    authors: Law W,Kwok TCY

    更新日期:2019-12-01 00:00:00

  • Association between depression and resilience in older adults: a systematic review and meta-analysis.

    abstract:OBJECTIVE:The objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations. METHOD:A systematic review and meta-analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis recommendations on th...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,meta分析

    doi:10.1002/gps.4619

    authors: Wermelinger Ávila MP,Lucchetti AL,Lucchetti G

    更新日期:2017-03-01 00:00:00

  • Accuracy of the short-form Montreal Cognitive Assessment: Systematic review and validation.

    abstract:INTRODUCTION:Short-form versions of the Montreal Cognitive Assessment (SF-MoCA) are increasingly used to screen for dementia in research and practice. We sought to collate evidence on the accuracy of SF-MoCAs and to externally validate these assessment tools. METHODS:We performed systematic literature searching across...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5162

    authors: McDicken JA,Elliott E,Blayney G,Makin S,Ali M,Larner AJ,Quinn TJ,VISTA-Cognition Collaborators.

    更新日期:2019-10-01 00:00:00

  • Subjective stressors moderate effectiveness of a multi-component, multi-site intervention on caregiver depression and burden.

    abstract:OBJECTIVES:The present study assessed whether caregiving contextual factors moderated outcomes of a caregiver intervention. METHODS:Extant data from the Resources for Enhancing Alzheimer's Caregiver Health (REACH) II study, a randomized-control trial of a multi-component, multi-site intervention for dementia caregiver...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/gps.4019

    authors: Hatch DJ,DeHart WB,Norton MC

    更新日期:2014-04-01 00:00:00

  • Suicide ideation, dementia and mental disorders among a community sample of older people in Mexico.

    abstract:UNLABELLED:Data on the prevalence of and risk factors for suicide ideation among older people in developing countries is lacking. OBJECTIVE:This study aimed to estimate if dementia and other mental disorders are associated with suicide ideation among the older people controlling for demographic and other suspected ris...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4134

    authors: Borges G,Acosta I,Sosa AL

    更新日期:2015-03-01 00:00:00

  • Length of hospital stay and dementia: A systematic review of observational studies.

    abstract:OBJECTIVE:Hospitalizations of people with dementia (PWD) are often accompanied by complications or functional loss and can lead to adverse outcomes. Unsystematic findings suggest an influence of comorbidities on the extent of differences in the length of hospital stay (LOS). This systematic review aimed to identify and...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4993

    authors: Möllers T,Stocker H,Wei W,Perna L,Brenner H

    更新日期:2019-01-01 00:00:00

  • Roles of serum fibrinogen α chain-derived peptides in Alzheimer's disease.

    abstract:OBJECTIVE:To find a blood biomarker and disease-related peptides in Alzheimer's disease (AD), we comprehensively detected serum peptides. METHODS:Ion intensity of serum peptides from 62 AD patients and 82 control subjects was measured by mass spectrometry. RESULTS:A total of 157 peptides were detected from 30 AD pati...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4047

    authors: Noguchi M,Sato T,Nagai K,Utagawa I,Suzuki I,Arito M,Iizuka N,Suematsu N,Okamoto K,Kato T,Yamaguchi N,Kurokawa MS

    更新日期:2014-08-01 00:00:00

  • Unrecognised psychological problems impair quality of life and increase consultation rates in Chinese elderly patients.

    abstract:OBJECTIVE:Studies have shown that psychological problems in elderly patients are often unrecognised in primary care. The aim of this study was to investigate the quality of life and consultation rates of Chinese elderly patients with unrecognised psychological problems in primary care. The prevalence and risk factors o...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,多中心研究

    doi:10.1002/gps.2210

    authors: Lam CL,Chin WY,Lee PW,Lo YY,Fong DY,Lam TP

    更新日期:2009-09-01 00:00:00

  • Patterns of late-life depressive symptoms and subsequent declines in cognitive domains.

    abstract:BACKGROUND:Depression frequently co-occurs with cognitive decline, but the nature of this association is unclear. We examined relations of late-life depressive symptom patterns to subsequent domain-specific cognitive changes. METHODS:Depressive symptoms were measured at up to 3 timepoints among 11,675 Nurses' Health S...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4618

    authors: Gillis JC,Chang SC,Devore EE,Rosner BA,Grodstein F,Okereke OI

    更新日期:2017-12-01 00:00:00

  • Consolidated framework for advancing implementation science for the implementation process and adherence assessment of a non-pharmacological delirium prevention program.

    abstract:OBJECTIVE:To evaluate the contribution of applying the theoretical framework of implementation science for adherence to non-pharmacological interventions to prevent delirium. METHODS:A quasi-experimental prospective design was conducted from March 2017 to October 2018 in a teaching hospital. Participants included 149 ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5425

    authors: Garrido MA,Alvarez EA,Ponce DP,Salech F,Tobar DI,Tobar EA

    更新日期:2021-02-01 00:00:00

  • Prescription opioid and benzodiazepine misuse is associated with suicidal ideation in older adults.

    abstract:OBJECTIVES:Suicide in older adults is a major public health issue. Past research across the US adult population has linked prescription medication misuse with suicidal ideation. No work has evaluated associations between prescription opioid or benzodiazepine misuse and suicidal ideation in older adults, and this work a...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4999

    authors: Schepis TS,Simoni-Wastila L,McCabe SE

    更新日期:2019-01-01 00:00:00

  • Role of physical activity in ameliorating neuropsychiatric symptoms in Alzheimer disease: A narrative review.

    abstract:OBJECTIVE:Neuropsychiatric symptoms (NPs) affect almost all patients with Alzheimer disease (AD). Because of the complications associated with the pharmacological treatment, nonpharmacological treatment (such as physical activity) can be considered as an additional complementary treatment option for NPs. The aim of thi...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,评审

    doi:10.1002/gps.4962

    authors: Veronese N,Solmi M,Basso C,Smith L,Soysal P

    更新日期:2019-09-01 00:00:00

  • Norms for the Mini-Mental State Examination from a sample of Sri Lankan older people.

    abstract:OBJECTIVE:To derive norms for the Mini Mental State Examination (MMSE) based on age, gender and level of formal education among the elderly in Sri Lanka. METHOD:A validated Sinhalese version of the MMSE was administered to people aged 55 years and above residing in 14 randomly selected elders' homes. Effects of age, g...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2168

    authors: De Silva R,Disanayaka S,De Zoysa N,Sanjeewanie N,Somaratne S,Foster J,Srikanth S,Kathriarachchi ST,Martins RM

    更新日期:2009-07-01 00:00:00

  • Effectiveness of DementiAbility Methods: The Montessori Way on agitation in long-term care home residents with dementia in Hong Kong.

    abstract:OBJECTIVE:To investigate the effect of the DementiAbility Methods: The Montessori Way (DMMW) on agitation in long-term care home residents with dementia. The activities using the DMMW are hypothesized to reduce agitation in terms of its frequency and disruptiveness to greater extent than structured social activities as...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.5063

    authors: Yuen I,Kwok T

    更新日期:2019-09-01 00:00:00

  • Atypical antipsychotic drug use and falls among nursing home residents in Winnipeg, Canada.

    abstract:OBJECTIVE:The purpose of this study is to assess whether atypical antipsychotic drug (AAD) use is associated with increased risk of falling among older (≥65 years) nursing home (NH) residents. METHODS:We conducted a nested case-control study using Resident Assessment Instrument Minimum Data Set 2.0 (RAI-MDS(©)) for NH...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.4223

    authors: Bozat-Emre S,Doupe M,Kozyrskyj AL,Grymonpre R,Mahmud SM

    更新日期:2015-08-01 00:00:00

  • Review of assessment and treatment of PTSD among elderly American armed forces veterans.

    abstract:BACKGROUND:The number of elderly combat veterans is steadily increasing in the US and estimates project that a notable percentage of these veterans experience symptoms of posttraumatic stress disorder (PTSD). Limited data exist specifically related to prevalence, assessment, and treatment of PTSD among the elderly vete...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,评审

    doi:10.1002/gps.1408

    authors: Owens GP,Baker DG,Kasckow J,Ciesla JA,Mohamed S

    更新日期:2005-12-01 00:00:00

  • Depressive symptoms among cognitively normal versus cognitively impaired elderly subjects.

    abstract:OBJECTIVES:The present cross-sectional study analyzed the prevalence and severity of depressive symptoms among patients with Alzheimer's disease (DAT), vascular dementia (VAD), and among the cognitively normal elderly. Putative risk factors contributing to depression were likewise evaluated. METHODS:Seventy-six DAT pa...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.360

    authors: Li Y,Meyer JS,Thornby J

    更新日期:2001-05-01 00:00:00

  • Citalopram versus other antidepressants for late-life depression: a systematic review and meta-analysis.

    abstract:OBJECTIVE:To determine the efficacy and tolerability of citalopram when compared to other antidepressants for late-life depression (LLD). METHODS:We searched electronic databases and trial registries to identify randomized controlled trials comparing citalopram to other antidepressants for LLD. Study quality was asses...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章,meta分析,评审

    doi:10.1002/gps.2483

    authors: Seitz DP,Gill SS,Conn DK

    更新日期:2010-12-01 00:00:00

  • Caregivers of people with Alzheimer's disease: a qualitative study from the Indian 10/66 Dementia Research Network.

    abstract:BACKGROUND:Dementia is a rapidly growing problem in all parts of the developing world. Such societies are characterised by low levels of awareness regarding dementia as a chronic degenerative brain syndrome, and by an absence of supportive health and welfare services. There is reliance upon families as the cornerstone ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.649

    authors: Shaji KS,Smitha K,Lal KP,Prince MJ

    更新日期:2003-01-01 00:00:00

  • Association of grip strength with dementia in a Korean older population.

    abstract:BACKGROUND:Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related fact...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2742

    authors: Shin HY,Kim SW,Kim JM,Shin IS,Yoon JS

    更新日期:2012-05-01 00:00:00

  • The relationship of neuropsychological function to instrumental activities of daily living in mild cognitive impairment.

    abstract:OBJECTIVE:While activities of daily living are by definition preserved in mild cognitive impairment (MCI), there is evidence of poorer instrumental activities of daily living (IADL) functioning in MCI compared to normal ageing. The aims of the present study were to examine differences in IADL between individuals with M...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2612

    authors: Reppermund S,Sachdev PS,Crawford J,Kochan NA,Slavin MJ,Kang K,Trollor JN,Draper B,Brodaty H

    更新日期:2011-08-01 00:00:00

  • Clinical differences between late-onset and early-onset chronically hospitalized elderly schizophrenic patients in Taiwan.

    abstract:OBJECTIVES:To examine the clinical differences between late-onset schizophrenia (LOS) and early-onset schizophrenia (EOS) in Taiwanese elderly chronic hospitalized schizophrenic patients. METHODS:By using a cross-sectional study method, we investigated all the hospitalized elderly schizophrenic patients in a general h...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2241

    authors: Huang C,Zhang YL

    更新日期:2009-10-01 00:00:00

  • Evaluation of the home help service and its impact on the informal caregiver's burden of dependent elders.

    abstract:AIM:This study looks at the objective and subjective characteristics of home respite service provision and its impact on the informal care burden of dependent elders. METHOD:A sample of 296 dependent people and their informal caregivers was randomly selected among users and non-users of the Home Help Service (HHS) in ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.1733

    authors: Carretero S,Garcés J,Ródenas F

    更新日期:2007-08-01 00:00:00

  • Plasma beta-amyloid and duration of Alzheimer's disease in adults with Down syndrome.

    abstract:OBJECTIVES:To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS:Adults with DS were recruited from community settings and followed up for ...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.2321

    authors: Prasher VP,Sajith SG,Mehta P,Zigman WB,Schupf N

    更新日期:2010-02-01 00:00:00

  • Serum cholesterol and depressive symptoms in elderly Finnish men.

    abstract:OBJECTIVE:Evidence from previous studies suggests that alterations in lipid levels may be associated with depression in old age. The objective of this study was to investigate the association between serum lipids and depressive symptoms in a population of elderly men. SUBJECTS AND METHODS:Altogether 470 men born betwe...

    journal_title:International journal of geriatric psychiatry

    pub_type: 杂志文章

    doi:10.1002/gps.666

    authors: Aijänseppä S,Kivinen P,Helkala EL,Kivelä SL,Tuomilehto J,Nissinen A

    更新日期:2002-07-01 00:00:00