Abstract:
BACKGROUND:Dementia is a major public health problem. Increased attention is being paid to the quality of life (QOL) of people with this chronic disease. There have been no longitudinal studies of QOL change in dementia. METHOD:Longitudinal study of a cohort of 47 persons with dementia residing in a long-term care facility. The QOL of participants was assessed at baseline using the Alzheimer's Disease Related Quality of Life (ADRQL) scale. At this time participants were also assessed on a series of other clinical measures. QOL was reassessed on the ADRQL scores two years later. RESULTS:There was small but significant mean decline in ADRQL over the two-year study interval. However, for 49% of participants, ADRQL scores did not change or improved. Small but significant declines occurred in all ADRQL domains, with the exception of 'feelings and mood'. Of the baseline variables assessed, only a lower baseline ADRQL score was associated with greater decline in ADRQL score at follow-up. There was no association between sociodemographic variables, baseline ratings of dementia severity (MMSE), ADL impairment, behavioral impairment, and depression, or MMSE change during follow-up and ADRQL decline. CONCLUSIONS:Among long-term care residents with dementia there is a small decline in QOL ratings over two years. However, for nearly half, QOL ratings stay the same or improve. The ADRQL is a sensitive measure of change in QOL and is appropriate for use as an outcome measure in intervention studies. The predictors of QOL change are complex and require further study.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Lyketsos CG,Gonzales-Salvador T,Chin JJ,Baker A,Black B,Rabins Pdoi
10.1002/gps.796subject
Has Abstractpub_date
2003-04-01 00:00:00pages
275-81issue
4eissn
0885-6230issn
1099-1166journal_volume
18pub_type
杂志文章abstract:OBJECTIVES:Older adults with psychiatric disorders have a substantially lower life expectancy than age-matched controls. Knowledge of risk factors may lead to targeting treatment and interventions to reduce this gap in life expectancy. In this study, we investigated whether frailty independently predicts mortality in o...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.5278
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:Cultural differences in how the symptoms, causes, consequences, and treatments of dementia are understood and interpreted by South Asian people are a commonly expressed reason for late- or nonuse of mental health and care services. However, systematic collection of information on South Asian perceptions of d...
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journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,多中心研究,评审
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更新日期:2008-01-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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更新日期:2018-01-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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abstract:OBJECTIVES:To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. METHODS/DESIGN:A population-based case-control study of a sample of 65 997 participants from the Survey of H...
journal_title:International journal of geriatric psychiatry
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journal_title:International journal of geriatric psychiatry
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更新日期:2002-03-01 00:00:00
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journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
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更新日期:2012-07-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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更新日期:2005-08-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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doi:10.1002/gps.1662
更新日期:2007-03-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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更新日期:2016-03-01 00:00:00
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journal_title:International journal of geriatric psychiatry
pub_type: 社论
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journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.2358
更新日期:2010-05-01 00:00:00
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journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章
doi:10.1002/gps.4359
更新日期:2016-05-01 00:00:00
abstract::Alzheimer's disease (AD) affects millions of people worldwide and the number of AD cases will increase with increased life expectancy. Today there is no cure for this devastating and always lethal disease and therefore it is of great interest for patients, relatives and societies to find new drugs that can hinder the ...
journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,评审
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更新日期:2005-02-01 00:00:00
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journal_title:International journal of geriatric psychiatry
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2016-02-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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更新日期:2017-02-01 00:00:00
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journal_title:International journal of geriatric psychiatry
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更新日期:2015-03-01 00:00:00
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journal_title:International journal of geriatric psychiatry
pub_type: 杂志文章,随机对照试验
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更新日期:2020-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2017-01-01 00:00:00
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更新日期:2005-10-01 00:00:00
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pub_type: 杂志文章
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更新日期:2000-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/gps.4404
更新日期:2016-08-01 00:00:00