Olanzapine in the treatment of anxiety symptoms due to Alzheimer's disease: a post hoc analysis.

abstract：OBJECTIVE:To elucidate the extent to which elderly people with cognitive impairment are able to answer questions about their quality of life.Design and setting308 elderly residents were interviewed within 2 weeks of admission to one of 30 residential or nursing homes in north-west England. MEASURES:The Mini-Mental Sta...

journal_title：International journal of geriatric psychiatry

authors： Mozley CG,Huxley P,Sutcliffe C,Bagley H,Burns A,Challis D,Cordingley L

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. METHODS:Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activit...

journal_title：International journal of geriatric psychiatry

authors： Jefferson AL,Cahn-Weiner D,Boyle P,Paul RH,Moser DJ,Gordon N,Cohen RA

更新日期：2006-08-01 00:00:00

abstract：OBJECTIVES:To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. METHODS/DESIGN:A population-based case-control study of a sample of 65 997 participants from the Survey of H...

journal_title：International journal of geriatric psychiatry

authors： Conde-Sala JL,Garre-Olmo J

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Acetyl Cholinesterase Inhibitors (AChEIs) have been in clinical use for the past five years in the UK for the symptomatic treatment of Alzheimer's disease (AD). There are few data on the patterns and predictors of response to AChEI therapy in routine clinical practice. We therefore investigated clinical vari...

journal_title：International journal of geriatric psychiatry

authors： Pakrasi S,Mukaetova-Ladinska EB,McKeith IG,O'Brien JT

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:To examine whether intensive care unit (ICU) admission is independently associated with increased risk of major depression in patients with diabetes. METHODS:This prospective cohort study included 3596 patients with diabetes enrolled in the Pathways Epidemiologic Follow-Up Study, of whom 193 had at least one...

journal_title：International journal of geriatric psychiatry

authors： Davydow DS,Hough CL,Russo JE,Von Korff M,Ludman E,Lin EH,Ciechanowski P,Young B,Oliver M,Katon WJ

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:We investigated the frequency and inter-relationship of neuropsychiatric disturbances in a population sample of persons suffering from Alzheimer's disease (AD). METHOD:Screening 5,092 elderly residents (90% of the population aged 65 and older) of Cache County, Utah, for dementia, we identified 198 persons wi...

journal_title：International journal of geriatric psychiatry

authors： Lyketsos CG,Sheppard JM,Steinberg M,Tschanz JA,Norton MC,Steffens DC,Breitner JC

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Mild cognitive impairment (MCI) is a clinical concept that categorizes subjects who are in an intermediate cognitive state between normal aging and dementia. The aim of this study is to characterize behavior in MCI compared with Alzheimer's disease (AD) and healthy older patients. DESIGN:A cross-sectional a...

journal_title：International journal of geriatric psychiatry

authors： Van der Mussele S,Le Bastard N,Vermeiren Y,Saerens J,Somers N,Mariën P,Goeman J,De Deyn PP,Engelborghs S

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Many studies have sought to determine the predictors of institutionalization of patients with dementia. Such studies, performed in developed western societies, have come to various conclusions which may not be supported in an East Asian culture such as that found in Korea. OBJECTIVES:This study aimed to det...

journal_title：International journal of geriatric psychiatry

authors： Kim JM,Shin IS,Jeong SJ,Gormley N,Yoon JS

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Most depression in older people is managed in primary care settings but can be difficult to diagnose and is often under-treated. This study examined the attitudes and practice of general practitioners in the treatment of late-life depression using antidepressant medication. METHOD:Three hundred and thirty g...

journal_title：International journal of geriatric psychiatry

authors： Rothera I,Jones R,Gordon C

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:The post-hoc analyses reported here evaluate the specific effects of memantine treatment on ADAS-cog single-items or SIB subscales for patients with moderate to severe AD. METHODS:Data from six multicentre, randomised, placebo-controlled, parallel-group, double-blind, 6-month studies were used as the basis ...

journal_title：International journal of geriatric psychiatry

authors： Mecocci P,Bladström A,Stender K

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of medication adherence to 12-month depression scores in the context of other psychosocial and clinical predictors of depression in a sample of older adults treated for depression. METHODS:Secondary analysis of a prospective cohort study involving 241 older patients undergoing dep...

journal_title：International journal of geriatric psychiatry

authors： Bosworth HB,Voils CI,Potter GG,Steffens DC

更新日期：2008-02-01 00:00:00

abstract：AIM:To determine rates of cerebral atrophy in individuals with symptoms of memory loss but no objective cognitive impairment (SNCI) and their association with future cognitive decline. METHODS:Thirty-two SNCI subjects, 16 with mild cognitive impairment (MCI) and 27 control subjects had clinical assessment and magnetic...

journal_title：International journal of geriatric psychiatry

authors： Archer HA,Kennedy J,Barnes J,Pepple T,Boyes R,Randlesome K,Clegg S,Leung KK,Ourselin S,Frost C,Rossor MN,Fox NC

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study is to determine whether resilience is associated with depressive symptoms in geriatric populations. METHOD:A systematic review and meta-analysis were performed (up to March 2015) following the Preferred Reporting Items for Systematic Reviews and Meta-analysis recommendations on th...

journal_title：International journal of geriatric psychiatry

authors： Wermelinger Ávila MP,Lucchetti AL,Lucchetti G

更新日期：2017-03-01 00:00:00

abstract：OBJECTIVE:This study identified factors in patients with diabetes associated with risk of developing dementia. RESEARCH DESIGN AND METHODS:This retrospective, longitudinal study used a national cohort of US Veterans with diabetes 65 years or older to examine incidence of dementia over 2 years. A multivariable Cox regr...

journal_title：International journal of geriatric psychiatry

authors： Parikh NM,Morgan RO,Kunik ME,Chen H,Aparasu RR,Yadav RK,Schulz PE,Johnson ML

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To describe the treatment of vocally disruptive behaviour (VDB) of multifactorial aetiology. METHOD:Three case reports were used to illustrate the treatment of multifactorial VDB. RESULTS:A biopsychosocial assessment is required to identify the different aetiologies involved and the way they interact. Acute...

journal_title：International journal of geriatric psychiatry

authors： Meares S,Draper B

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:The management of Behavioural and Psychological Symptoms of Dementia (BPSD) has been the subject of considerable debate over the last few years in view of the poor evidence base for pharmacological agents and concerns about their safety. OBJECTIVES:This study sought to obtain expert opinion on the managemen...

journal_title：International journal of geriatric psychiatry

authors： Bishara D,Taylor D,Howard RJ,Abdel-Tawab R

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND:Despite a consensus on the need to expand and improve mental health care for older people, evidence on models of service development is limited. OBJECTIVE:Referring to two case studies, this paper considers how evaluation of service innovations can inform policy and practice. CONCLUSIONS:Evaluation should ...

journal_title：International journal of geriatric psychiatry

authors： McCrae N,Banerjee S

更新日期：2011-06-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:To compare directly, in the same patient cohort, the ease of use and tolerability of donepezil and galantamine in the treatment of Alzheimer's disease (AD), and investigate the effects of both treatments on cognition and activities of daily living (ADL). METHODS:Patients with mild to moderate AD from 14 Eur...

journal_title：International journal of geriatric psychiatry

authors： Jones RW,Soininen H,Hager K,Aarsland D,Passmore P,Murthy A,Zhang R,Bahra R

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:This study explored whether patients with late-onset major depressive disorder showed higher carotid artery intima-medium thickness (IMT) and investigated the relationship between the IMT and white matter hyperintensities on magnetic resonance imaging (MRI) among patients. METHODS:Fourteen elderly patients ...

journal_title：International journal of geriatric psychiatry

authors： Chen CS,Chen CC,Kuo YT,Chiang IC,Ko CH,Lin HF

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The 10/66 Dementia Research Group developed and validated a culture and education fair battery of cognitive tests for diagnosis of dementia in population-based studies in low-income and middle-income countries including India. AIMS:This study examined the association between individual domains of the 10/66 ...

journal_title：International journal of geriatric psychiatry

authors： Krishna M,Beulah E,Jones S,Sundarachari R,A S,Kumaran K,Karat SC,Copeland JR,Prince M,Fall C

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to predict rehospitalisation in a psychiatric clinic in older inpatients with a psychotic disorder. METHODS/DESIGN:In this prospective, observational study, all eligible inpatients aged 55 years and over with a primary psychotic disorder, admitted to a specialised ward for old...

journal_title：International journal of geriatric psychiatry

authors： Kist N,van den Berg JF,Kok RM

更新日期：2020-05-18 00:00:00

abstract：BACKGROUND:The association between depression and an increased risk of death in elderly persons has been established in both clinical and community studies. Co-occurrence of depression and generalized anxiety has been shown to represent more severe and more chronic psychopathology. However, little is known about the re...

journal_title：International journal of geriatric psychiatry

authors： Holwerda TJ,Schoevers RA,Dekker J,Deeg DJ,Jonker C,Beekman AT

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVES:Using a cross-sectional community survey, the authors aimed to estimate the prevalence of dementia among a sample of older Jamaicans and to identify associated demographic factors. METHODS:From February to July 2010, persons of age ≥60 years were randomly selected from two communities in Kingston, Jamaica a...

journal_title：International journal of geriatric psychiatry

authors： Neita SM,Abel WD,Eldemire-Shearer D,James K,Gibson RC

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:The IDEAL Schedule was developed for staging "care needs" in patients with dementia. We here aim to validate the Spanish version, further test its psychometric properties and explore a latent construct for "care needs". METHODS:A multicenter study was done in 8 dementia care facilities across Spain. Patients...

journal_title：International journal of geriatric psychiatry

authors： López-Antón R,Barrada JR,Santabárbara J,Posadas-de Miguel M,Agüera L,Burillo C,Franco M,López-Álvarez J,Mesa P,Petidier R,Quintanilla MÁ,Robles-Del Olmo B,Ventura T,Semrau M,Sartorius N,Lobo A,the members of the IDEAL Spa

更新日期：2018-03-01 00:00:00

abstract：:Nine policy preoccupations have been identified in a recent study of dementia care policies in all European countries. These are used to structure a set of issues which researchers might usefully address to assist service planners and policy-makers. Areas where there is already a research literature are identified. So...

journal_title：International journal of geriatric psychiatry

authors： Marshall M

更新日期：1999-02-01 00:00:00

abstract：OBJECTIVE:Memory complaints in the absence of objective test impairments are common. Only a subset of these subjects seeks medical attention for these complaints. The aim of the present study was to investigate which factors determine why people with subjective memory complaints (SMC) seek medical attention. METHODS:T...

journal_title：International journal of geriatric psychiatry

authors： Ramakers IH,Visser PJ,Bittermann AJ,Ponds RW,van Boxtel MP,Verhey FR

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:This study aimed to: (i) replicate previous findings that women experience more strain and distress than men when caring for dementing spouses; (ii) explore what factors underlie this sex difference. DESIGN:Two closely matched subsamples of spouse carers, husbands and wives respectively, were selected and th...

journal_title：International journal of geriatric psychiatry

authors： Collins C,Jones R

更新日期：1997-12-01 00:00:00

abstract：OBJECTIVE:Rivastigmine, a dual cholinesterase inhibitor (ChEI), is widely approved for the symptomatic treatment of both mild-to-moderate Alzheimer's disease (AD) and Parkinson's disease dementia. Orally administered ChEIs may be associated with gastrointestinal (GI) side effects and add-on therapy with memantine, an N...

journal_title：International journal of geriatric psychiatry

authors： Olin JT,Bhatnagar V,Reyes P,Koumaras B,Meng X,Brannan S

更新日期：2010-04-01 00:00:00

abstract：OBJECTIVE:To assess the cost effectiveness of cholinesterase inhibitor (ChEI) treatment in patients with Alzheimer's disease (AD) and Dementia with Lewy bodies (DLB). METHOD:We used 4-month open label follow-up data from routine memory clinic patients. There were 852 patients with AD and 112 with DLB. We applied three...

journal_title：International journal of geriatric psychiatry

authors： Gustavsson A,Van Der Putt R,Jönsson L,McShane R

更新日期：2009-10-01 00:00:00