Abstract：
BACKGROUND:The association between depression and an increased risk of death in elderly persons has been established in both clinical and community studies. Co-occurrence of depression and generalized anxiety has been shown to represent more severe and more chronic psychopathology. However, little is known about the relation between generalized anxiety disorder, mixed anxiety-depression (generalized anxiety disorder and depression) and excess mortality in the elderly. OBJECTIVE:To investigate whether generalized anxiety and mixed anxiety-depression are associated with mortality. METHOD:Generalized anxiety disorder, mixed anxiety-depression and depression were assessed in 4051 older persons with a ten-year follow-up of community death registers. The mortality risk of generalized anxiety, depression and mixed anxiety-depression was calculated after adjustment for demographic variables, physical illness, functional disabilities and social vulnerability. RESULTS:In generalized anxiety disorder and mixed anxiety-depression no significant excess mortality was found. In depression a significant excess mortality was found in men [HR 1.44 (1.09-1.89)] but not in women [HR 1.04 (0.87-1.24)] after adjustment for the different variables. CONCLUSIONS:In elderly persons depression increases the risk of death in men. Neither generalized anxiety nor mixed anxiety-depression are associated with excess mortality. Generalized anxiety disorder may even predict less mortality in depressive elderly people. The relation between generalized anxiety disorder and its possibly protective effect on mortality has to be further explored.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Holwerda TJ,Schoevers RA,Dekker J,Deeg DJ,Jonker C,Beekman ATdoi
10.1002/gps.1669subject
Has Abstractpub_date
2007-03-01 00:00:00pages
241-9issue
3eissn
0885-6230issn
1099-1166journal_volume
22pub_type
杂志文章abstract：OBJECTIVE:The aim of this study was to examine whether delirium has specific clinical subtypes. METHOD:One hundred and eighty-three elderly subjects meeting DSM-IIIR criteria for delirium were evaluated using a 19-item symptom check-list assessing different dimensions of delirium symptomatology. Exploratory factor ana...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(200004)15:4<313::aid-gps11
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:This study explored whether patients with late-onset major depressive disorder showed higher carotid artery intima-medium thickness (IMT) and investigated the relationship between the IMT and white matter hyperintensities on magnetic resonance imaging (MRI) among patients. METHODS:Fourteen elderly patients ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1420
更新日期：2006-01-01 00:00:00
abstract：BACKGROUND:Dementia is a rapidly growing problem in all parts of the developing world. Such societies are characterised by low levels of awareness regarding dementia as a chronic degenerative brain syndrome, and by an absence of supportive health and welfare services. There is reliance upon families as the cornerstone ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.649
更新日期：2003-01-01 00:00:00
abstract：BACKGROUND:Alzheimer's disease (AD) causes progressive loss of memory and disability, especially in older people. As worldwide population grows older, AD is responsible for an important social and economical burden in many nations. People suffering from AD may experience health-related stigma that influences their atti...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.3903
更新日期：2013-09-01 00:00:00
abstract：OBJECTIVES:Since plasma protein binding of tricyclic antidepressants may be relevant to treatment effects and can be influenced by age-associated factors, we examined both plasma ultrafiltrate and total concentrations of nortriptyline (NT) in patients and compared these to age. We hypothesized negative associations wit...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/1099-1166(200011)15:11<1009::aid-gps228>3.
更新日期：2000-11-01 00:00:00
abstract：OBJECTIVES:To investigate the efficacy of the chronic usage of the cholinesterase inhibitor rivastigmine in patients with dementia in the prevention of delirium in case of hospitalisation. DESIGN:Retrospective cohort study. SETTING:Non-geriatric wards of an 1120 bed general teaching hospital in s-Hertogenbosch, The N...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1138
更新日期：2004-07-01 00:00:00
abstract：:Nine policy preoccupations have been identified in a recent study of dementia care policies in all European countries. These are used to structure a set of issues which researchers might usefully address to assist service planners and policy-makers. Areas where there is already a research literature are identified. So...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199902)14:2<86::aid-gps940
更新日期：1999-02-01 00:00:00
abstract：BACKGROUND:The subtypes and risk factors of neuropsychiatric symptoms remain largely unexplored in South-East Asian populations. OBJECTIVE:We investigated the prevalence, subtypes, and risk factors, namely, demographic, medical morbidity, and cognitive impairment associated with neuropsychiatric symptoms in a South-Ea...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4693
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVE:It is unclear whether patients with late onset and patients with early onset present with different subtypes of depression. The aim of the study was to compare the prevalence of subtypes of ICD-10 single depressive episodes for patients with late onset (age >65 years) and patient with early onset (age < or = ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1617
更新日期：2006-12-01 00:00:00
abstract：:This cross-sectional study explored age-related differences in the frequency of diagnosis of personality disorder (PD) among 790 veterans admitted to a psychiatric inpatient unit across three age groups: 20-39, 40-59, and 60+. Older adults obtained a lower frequency (55.4%) of PD diagnosis than middle-aged adults (69....
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/1099-1166(200009)15:9<831::aid-gps208>3.0.
更新日期：2000-09-01 00:00:00
abstract：BACKGROUND:The paper explores the diverse ethical issues in the care of persons with dementia, in the Netherlands and Kerala, India. These cross-cultural data are used to suggest newer ways for addressing the ethical issues in a mutually enhancing manner. METHODS:A thorough review of the literature focusing on ethical...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.2127
更新日期：2009-04-01 00:00:00
abstract：OBJECTIVE:To identify carer and patient characteristics associated with various aspects of burden of care. METHOD:The burden on 196 carers, each caring for one patient with dementia, was rated by means of the Relative Stress Scale (RSS). Patients were assessed with the Mini Mental State Examination (MMSE), the Disabil...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1654
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To establish the factor structure, reliability and validity of a brief CESD scale among Community dwelling older adults in Singapore. METHOD:Data were derived from interviews conducted among 1,013 randomly selected non-institutionalized older adults aged 65 years and above in Singapore. First, Confirmatory F...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1944
更新日期：2008-06-01 00:00:00
abstract：OBJECTIVE:This article analyses behaviour changes in dementia at the point of entry to a longitudinal study. DESIGN:Prospective, longitudinal study of behaviour in dementia, with autopsy follow-up. SETTING:Subjects with dementia, living at home with a carer. All lived in Oxfordshire, UK. PARTICIPANTS:Ninety-seven pe...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199711)12:11<1062::aid-gps
更新日期：1997-11-01 00:00:00
abstract：OBJECTIVE:We evaluated the feasibility and acceptability of a tailored evidence-based intervention, consisting of a leaflet and a letter, to encourage timely help-seeking for dementia in Black elders. METHODS:Participating GP surgeries were randomised to send either the intervention or a control leaflet about ageing w...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,随机对照试验
doi：10.1002/gps.4891
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Several studies have found that low grip strength is associated with dementia in Western populations. However, there have been few studies in Asian populations. This cross-sectional study aimed to examine whether grip strength is independently associated with dementia after controlling for other related fact...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2742
更新日期：2012-05-01 00:00:00
abstract：OBJECTIVE:In both dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD), attentional dysfunction is a core clinical feature together with disrupted episodic memory. This study evaluated the cognitive effects of memantine in DLB and PDD using automated tests of attention and episodic memory. METHODS:A ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1002/gps.4109
更新日期：2015-01-01 00:00:00
abstract：OBJECTIVE:To elucidate the extent to which elderly people with cognitive impairment are able to answer questions about their quality of life.Design and setting308 elderly residents were interviewed within 2 weeks of admission to one of 30 residential or nursing homes in north-west England. MEASURES:The Mini-Mental Sta...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：
更新日期：1999-09-01 00:00:00
abstract：OBJECTIVES:Research indicates increasing trends among older adults toward heavy and abusive drinking, often associated with depressive symptoms. Possible exceptions are residents of planned retirement communities, whose drinking may be associated with social activities. To better understand these relationships, this st...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4359
更新日期：2016-05-01 00:00:00
abstract：:Less than one-tenth of all population-based research into dementia is directed towards the two-thirds or more of cases living in developing parts of the world. The 10/66 Dementia Research Group has been formed to redress this imbalance, encouraging active research collaboration between centres in different developing ...
journal_title：International journal of geriatric psychiatry
pub_type： 共识发展会议,杂志文章,评审
doi：10.1002/(sici)1099-1166(200001)15:1<14::aid-gps70>
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:Describe novel methods for ascertaining verbal fluency in a large national sample of adults, examine demographic factors influencing performance, and compare scores to studies using in-person assessment. METHODS/DESIGN:Participants were from the Reasons for Geographic and Racial Differences in Stroke (REGAR...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5054
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVES:The purpose of this study was to identify whether the onset and the end of fear of falling (FOF) are associated with psychosocial consequences (in terms of depressive symptoms, loneliness, social isolation, autonomy, and subjective well-being). METHODS/DESIGN:Longitudinal data for this study were taken from...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5325
更新日期：2020-09-01 00:00:00
abstract：OBJECTIVE:To compare the 6 and 12 month outcomes of patients who recovered from delirium by 8 weeks with those who did not have an index episode. METHODS:Older medical inpatients were assessed for delirium using the Confusion Assessment Method. All patients with delirium and a sample of patients without delirium were ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1878
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:Subjects with mild cognitive impairment (MCI) may revert to normal cognition (NC), but predictive factors are under study. We therefore sought to identify factors which could help in predicting reversion from MCI to NC. METHODS:Relevant studies were retrieved from PubMed, EMBASE, Cochrane Library, MEDLINE, W...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,meta分析,评审
doi：10.1002/gps.5159
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:Cross validation study of the MoCA for the detection of Alzheimer's disease (AD) and Mild Cognitive Impairment (MCI) in a community-based cohort residing in the Southeastern United States. METHODS:One hundred and eighteen English-speaking older adults, who underwent diagnostic evaluation as part of an on-goi...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2101
更新日期：2009-02-01 00:00:00
abstract：OBJECTIVE:Previous studies have reported depressive symptoms in the preclinical stages of Alzheimer's disease (AD). The objective of this study was to determine whether depressive symptoms are associated with cortical amyloid burden. In order to do this, we measured cortical amyloid via (11) C-labeled Pittsburgh Compou...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4409
更新日期：2016-08-01 00:00:00
abstract：OBJECTIVES:To gain more insight into the association between severity of Alzheimer's Disease (AD) and prevalence of comborbid depression. METHODS:A systematic literature review based on the Cochrane methodology was performed. PubMed, PsychINFO and EMBASE databases were searched for existing studies that fulfilled pred...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.1809
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:This paper provides an initial evaluation of the impact of the Single Assessment Process (SAP) in England upon practice regarding multidisciplinary assessment. OBJECTIVES:To investigate changes in recorded health needs of older people and in the number of multidisciplinary assessments undertaken using socia...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2069
更新日期：2008-12-01 00:00:00
abstract：OBJECTIVE:Apathy is a prominent and disabling symptom in Parkinson's disease (PD) and is a multidimensional behaviour, but which dimensions are specifically affected is unclear. Therefore, the aim of this preliminary study was to determine the psychometric properties of the Dimensional Apathy Scale (DAS) and explore th...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4697
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Hoarding disorder (HD) is a chronic and debilitating psychiatric condition. Midlife HD patients have been found to have neurocognitive impairment, particularly in areas of executive functioning, but the extent to which this is due to comorbid psychiatric disorders has not been clear. AIMS/METHOD:The purpose...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.3940
更新日期：2013-11-01 00:00:00
