Cognitive predictors of functional decline in vascular dementia.

abstract：OBJECTIVES:Little research has explored how cognitive function and activities of daily living (ADL) affect each other over time. In addition, no current finding provides a clear hint to the temporal precedence between them. The present study tries to address these limitations of prior studies by utilizing a longitudina...

journal_title：International journal of geriatric psychiatry

authors： Wang J,Zhu WH,Li YF,Zhu WW

更新日期：2019-12-01 00:00:00

abstract：OBJECTIVES:To explore the extent of and factors associated with male residents who change wandering status post nursing home admission. DESIGN:Longitudinal design with secondary data analyses. Admissions over a 4-year period were examined using repeat assessments with the Minimum Data Set (MDS) to formulate a model un...

journal_title：International journal of geriatric psychiatry

authors： King-Kallimanis B,Schonfeld L,Molinari VA,Algase D,Brown LM,Kearns WD,Davis DM,Werner DH,Beattie ER,Nelson AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Exposure to negative life events (NLEs) and neuroticism are associated with dementia. It is unknown whether neuroticism explains or modifies the association of NLEs with dementia in older Black and White Brazilians. METHODS:A total of 1747 decedents 65 years and older White and Black (11% Black and 23% Mixed...

journal_title：International journal of geriatric psychiatry

authors： Capuano AW,Wilson RS,Leurgans SE,Sampaio C,Barnes LL,Farfel JM,Bennett DA

更新日期：2020-12-30 00:00:00

abstract：OBJECTIVE:In the Netherlands, persons of Turkish, Moroccan and Surinamese descent form the largest groups of non-western immigrants. A high prevalence of mild cognitive impairment (MCI) and dementia has been described in immigrant populations in the United States of America and the United Kingdom. We determined the pre...

journal_title：International journal of geriatric psychiatry

authors： Parlevliet JL,Uysal-Bozkir Ö,Goudsmit M,van Campen JP,Kok RM,Ter Riet G,Schmand B,de Rooij SE

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVE:We hypothesized that cerebral amyloid accumulation is reflected in the periphery in the pre-dementia stage and used flow cytometry to investigate the peripheral lymphocytes as an easily accessible biomarker to observe neuro-inflammation. We aimed to determine whether peripheral lymphocytes are related to the ...

journal_title：International journal of geriatric psychiatry

authors： Yasuno F,Kazui H,Kajimoto K,Ihara M,Morita N,Taguchi A,Yamamoto A,Matsuoka K,Takahashi M,Nakagawara J,Tsuji M,Iida H,Kishimoto T,Nagatsuka K

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVES:Depression in late life has been associated with difficulties in cognitive processing, particularly in the domains of executive function, processing speed and memory, and increases the risk of developing dementia suggesting a neurodegenerative phenotype. Mitochondrial dysfunction is frequently an early event...

journal_title：International journal of geriatric psychiatry

authors： Harper DG,Joe EB,Jensen JE,Ravichandran C,Forester BP

更新日期：2016-11-01 00:00:00

abstract：OBJECTIVES:To assess the association between early parental death and the risk of dementia in adult life and to examine the risk factors associated with early parental death in people with and without dementia. METHODS/DESIGN:A population-based case-control study of a sample of 65 997 participants from the Survey of H...

journal_title：International journal of geriatric psychiatry

authors： Conde-Sala JL,Garre-Olmo J

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:Impaired insight into illness is a prevalent feature of schizophrenia, which negatively influences treatment adherence and clinical outcomes. Little is known about the effects of aging on insight impairment. We aimed to review the available research literature on the effects of aging on insight into illness ...

journal_title：International journal of geriatric psychiatry

authors： Gerretsen P,Plitman E,Rajji TK,Graff-Guerrero A

更新日期：2014-11-01 00:00:00

abstract：:Divalproex is now commonly used to treat bipolar disorder in older patients. However, it has yet to be systematically studied in this population. This report describes six older bipolar patients treated with divalproex. Of the six, five showed some improvement with divalproex alone or in combination with other agents....

journal_title：International journal of geriatric psychiatry

authors： Mordecai DJ,Sheikh JI,Glick ID

更新日期：1999-06-01 00:00:00

abstract：OBJECTIVE:To determine whether attentional impairments are reliable neuropsychological markers of sub syndrome delirium. METHOD:A prospective cohort study with repeated assessment beginning pre-operatively and continuing through the first post-operative week. Computerized assessments of attention and the Mini-Mental S...

journal_title：International journal of geriatric psychiatry

authors： Lowery DP,Wesnes K,Brewster N,Ballard C

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:Late-life depression (LLD) is the association with more cerebrovascular susceptibilities and white matter damage that can be assessed with diffusion tensor imaging (DTI). To better understand the white matter pathological alterations in LLD, we conducted a systematic review and meta-analysis. METHODS:We sea...

journal_title：International journal of geriatric psychiatry

authors： Wen MC,Steffens DC,Chen MK,Zainal NH

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:The ventrolateral prefrontal cortex (vlPFC) has been speculated to play an important role in complex processes that allow emotional factors to influence human cognition. Accumulating evidence from human neuroimaging studies, in conjunction with studies of patients with lesions and animal models, shed light o...

journal_title：International journal of geriatric psychiatry

authors： Kim JU,Weisenbach SL,Zald DH

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVE:To determine incidence and risk factors for the development of postoperative acute confusional state (ACS) in the elderly. DESIGN:A prospective cohort study. SETTING:University hospital. PATIENTS:One hundred and five consecutive patients without ACS at baseline who underwent hip surgery because of hip frac...

journal_title：International journal of geriatric psychiatry

authors： Galanakis P,Bickel H,Gradinger R,Von Gumppenberg S,Förstl H

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Despite the fact that the current definitions of dementia in the DSM-IV and ICD-10 require functional deterioration for the diagnosis of dementia, it is not necessary a formal evaluation of functional capacity. OBJECTIVES:To examine the efficiency of functional assessment as a method of screening dementia i...

journal_title：International journal of geriatric psychiatry

authors： Castilla-Rilo J,López-Arrieta J,Bermejo-Pareja F,Ruiz M,Sánchez-Sánchez F,Trincado R

更新日期：2007-09-01 00:00:00

abstract：RATIONALE:Quetiapine was approved in Germany as an atypical antipsychotic for treatment of schizophrenia in 2000, followed by the approval as an antipsychotic for treatment of bipolar mania in 2003. The approval of quetiapine for treatment of bipolar depression is expected. We hypothesized that the psychogeriatric pres...

journal_title：International journal of geriatric psychiatry

authors： Hilwerling L,Juckel G,Schröder SG

更新日期：2007-05-01 00:00:00

abstract：OBJECTIVE:We hypothesize that the personality influences the caregiver's depression, burden and distress related to BPSD. SUBJECTS AND METHODS:Participants were 105 consecutive patients with dementia and their family caregivers, living at home, attending a Dementia Clinic. A cross-sectional design was used with an app...

journal_title：International journal of geriatric psychiatry

authors： Melo G,Maroco J,de Mendonça A

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to evaluate the effect of tumour necrosis factor-alpha inhibitors (TNF-αI) on Alzheimer's disease-associated pathology. DESIGN:A literature search of PubMed, Embase, PsychINFO, Web of Science, Scopus, and the Cochrane Library databases for human and animal studies that evalua...

journal_title：International journal of geriatric psychiatry

authors： Ekert JO,Gould RL,Reynolds G,Howard RJ

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVES:In primary care 50-95% of patients with depression present with vegetative symptoms (VS). Based on the extant literature, older adults showing VS (but no dysphoria) may show functional impairment but this hypothesis has not been empirically tested. The goal of this study was to examine neurocognitive and dai...

journal_title：International journal of geriatric psychiatry

authors： Paradiso S,Duff K,Vaidya JG,Hoth A,Mold JW

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Cognitive screening instruments are either too long for routine clinical use or not sensitive to distinguish mild cognitive impairment (MCI) from normal cognition (NC) or dementia. OBJECTIVE:To evaluate the sensitivity and specificity of the AB Cognitive Screen (ABCS) and its subtests with a view to improvi...

journal_title：International journal of geriatric psychiatry

authors： Standish TI,Molloy DW,Cunje A,Lewis DL

更新日期：2007-03-01 00:00:00

abstract：:Family members incur substantial financial costs during the course of caring for an individual with Alzheimer's disease. Much of this cost is associated with time spent in caregiving tasks, including supervision and communication with the patient, and assisting with activities of daily living. We have previously repor...

journal_title：International journal of geriatric psychiatry

authors： Marin DB,Dugue M,Schmeidler J,Santoro J,Neugroschl J,Zaklad G,Brickman A,Schnur E,Hoblyn J,Davis KL

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The aims of this study were to explore the knowledge, attitudes and beliefs that nursing home managers hold with regard to the assessment and management of pain in residents with dementia and to determine how these may be affected by the demographic characteristics of the respondents. METHODS:A questionnair...

journal_title：International journal of geriatric psychiatry

authors： Barry HE,Parsons C,Peter Passmore A,Hughes CM

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:In order to study secular changes in personality factors neuroticism and extroversion, representative population samples of non-demented 75-year-olds underwent psychiatric examinations in 1976-1977 (total n = 223, 138 women, 85 men) and 2005-2006 (total n = 556, 322 women and 234 men). METHODS:Eysenck Person...

journal_title：International journal of geriatric psychiatry

authors： Billstedt E,Waern M,Duberstein P,Marlow T,Hellström T,Ostling S,Skoog I

更新日期：2013-03-01 00:00:00

abstract：OBJECTIVE:This study examined the attribution of mild cognitive impairment (MCI) etiology assigned by individuals with MCI and their care partners, and the extent to which the dyads agreed on the attribution of MCI etiology. METHODS:We conducted secondary analyses of cross-sectional data from a cohort of individuals w...

journal_title：International journal of geriatric psychiatry

authors： Rodakowski J,Schulz R,Gentry A,Garand L,Lingler JH

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Ischaemic vascular dementia shares risk factors with stroke. There is evidence that control of these risk factors may prevent or alter the course of vascular dementia. OBJECTIVE:To assess the effect of regular low-dose aspirin on outcomes for patients with vascular dementia. DESIGN:Retrospective analysis o...

journal_title：International journal of geriatric psychiatry

authors： Devine ME,Rands G

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Psychosis, like other neuropsychiatric symptoms of dementia, has many features that make predictive modeling of its onset difficult. For example, psychosis onset is associated with both the absolute degree of cognitive impairment and the rate of cognitive decline. Moreover, psychotic symptoms, while more like...

journal_title：International journal of geriatric psychiatry

authors： Seltman HJ,Mitchell S,Sweet RA

更新日期：2016-02-01 00:00:00

abstract：:Reduced N-acetyl aspartate (NAA) and increased myo-inositol (MI) levels have been reported in patients with dementia of Alzheimer type (DAT) in comparison with controls. We wished to assess the validity of these findings and to evaluate possible correlations of metabolite proportions with cognitive dysfunction in DAT....

journal_title：International journal of geriatric psychiatry

authors： Heun R,Schlegel S,Graf-Morgenstern M,Tintera J,Gawehn J,Stoeter P

更新日期：1997-03-01 00:00:00

abstract：OBJECTIVES:To investigate a presumed correlation between clock drawing ratings and linear measurements of computerized tomography (CT) studies in demented patients. DESIGN:Blinded evaluations of clock drawing tests and CT studies of elderly dementia patients were conducted by a geriatric psychiatrist and a neuroradiol...

journal_title：International journal of geriatric psychiatry

authors： Heinik J,Reider-Groswasser II,Solomesh I,Segev Y,Bleich A

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Depression is common in Alzheimer's disease (AD; 5-35%). It is associated with increased disability, cost of care and carer burden. Exercise is known to be associated with a lower prevalence of depression across the age range but little is known about its relationship to depression in AD. AIMS:To investigat...

journal_title：International journal of geriatric psychiatry

authors： Regan C,Katona C,Walker Z,Livingston G

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVE:To evaluate the cost-consequences of an intervention for the management of neuropsychiatric symptoms in nursing home residents with young-onset dementia. METHODS:A stepped wedge design was used. The intervention consisted of an educational program and a multidisciplinary care program and was implemented in 1...

journal_title：International journal of geriatric psychiatry

authors： van Duinen-van den IJssel JCL,Bakker C,Smalbrugge M,Zwijsen SA,Adang E,Appelhof B,Zuidema SU,de Vugt ME,Verhey FRJ,Koopmans RTCM

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:There is limited literature around peer research in dementia. This study aims to identify the benefits, the risks and the practical challenges and to develop a model of good practice in peer research with people with dementia. METHODS:We searched on PsycInfo, PubMed and Google Scholar for empirical investig...

journal_title：International journal of geriatric psychiatry

authors： Di Lorito C,Birt L,Poland F,Csipke E,Gove D,Diaz-Ponce A,Orrell M

更新日期：2017-01-01 00:00:00