Safety and tolerability of rivastigmine capsule with memantine in patients with probable Alzheimer's disease: a 26-week, open-label, prospective trial (Study ENA713B US32).

abstract：OBJECTIVE:To compare the 6 and 12 month outcomes of patients who recovered from delirium by 8 weeks with those who did not have an index episode. METHODS:Older medical inpatients were assessed for delirium using the Confusion Assessment Method. All patients with delirium and a sample of patients without delirium were ...

journal_title：International journal of geriatric psychiatry

authors： Cole MG,You Y,McCusker J,Ciampi A,Belzile E

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:Neuropsychiatric symptoms (NPs) affect almost all patients with Alzheimer disease (AD). Because of the complications associated with the pharmacological treatment, nonpharmacological treatment (such as physical activity) can be considered as an additional complementary treatment option for NPs. The aim of thi...

journal_title：International journal of geriatric psychiatry

authors： Veronese N,Solmi M,Basso C,Smith L,Soysal P

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVES:To examine the clinical differences between late-onset schizophrenia (LOS) and early-onset schizophrenia (EOS) in Taiwanese elderly chronic hospitalized schizophrenic patients. METHODS:By using a cross-sectional study method, we investigated all the hospitalized elderly schizophrenic patients in a general h...

journal_title：International journal of geriatric psychiatry

authors： Huang C,Zhang YL

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Late-life depression (LLD) is the association with more cerebrovascular susceptibilities and white matter damage that can be assessed with diffusion tensor imaging (DTI). To better understand the white matter pathological alterations in LLD, we conducted a systematic review and meta-analysis. METHODS:We sea...

journal_title：International journal of geriatric psychiatry

authors： Wen MC,Steffens DC,Chen MK,Zainal NH

更新日期：2014-12-01 00:00:00

abstract：BACKGROUND:Disturbance of sleep is common in individuals with dementia where there may be reversal of the sleep-wake cycle. People with dementia of the Alzheimer's type have melatonin secretion rhythm disorders. There is some evidence that treatment with exogenous melatonin is an effective treatment for sleep disturban...

journal_title：International journal of geriatric psychiatry

authors： Serfaty M,Kennell-Webb S,Warner J,Blizard R,Raven P

更新日期：2002-12-01 00:00:00

abstract：OBJECTIVE:Previous studies have reported depressive symptoms in the preclinical stages of Alzheimer's disease (AD). The objective of this study was to determine whether depressive symptoms are associated with cortical amyloid burden. In order to do this, we measured cortical amyloid via (11) C-labeled Pittsburgh Compou...

journal_title：International journal of geriatric psychiatry

authors： Yasuno F,Kazui H,Morita N,Kajimoto K,Ihara M,Taguchi A,Yamamoto A,Matsuoka K,Kosaka J,Kudo T,Iida H,Kishimoto T,Nagatsuka K

更新日期：2016-08-01 00:00:00

abstract：OBJECTIVES:The aims of this study were to identify factors of significance in the development of acute confusional state (ACS) and the differences between patients who developed ACS and those who did not. METHOD AND RESULTS:Assessment, observations and interviews with 505 patients admitted to an orthopaedic clinic rev...

journal_title：International journal of geriatric psychiatry

authors： Andersson EM,Gustafson L,Hallberg IR

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:The objective of this study was to assess the measurement properties of the self-reported Patient Health Questionnaire-9 (PHQ-9) and its 10-item observer version (PHQ-10OV) among nursing home residents. METHODS:We conducted a retrospective study of Minimum Data Set 3.0 assessments for national cohorts of Me...

journal_title：International journal of geriatric psychiatry

authors： Bélanger E,Thomas KS,Jones RN,Epstein-Lubow G,Mor V

更新日期：2019-05-01 00:00:00

abstract：OBJECTIVE:To determine the national prevalence of psychotropic use and association with neuropsychiatric symptoms among patients with dementia. METHODS:Participants diagnosed with dementia (n = 414) in the Aging, Demographics, and Memory Study, a nationally representative survey of US adults >70 years old. Diagnosis w...

journal_title：International journal of geriatric psychiatry

authors： Maust DT,Langa KM,Blow FC,Kales HC

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:the present study reports on the first translation and use of the Cornell Scale for Depression in Dementia (CSDD) (Alexopoulos, Abrams, Young, & Shamoian, 1988) among poststroke patients (n = 101) in Japan. OBJECTIVES:the study had three main purposes: 1. To examine the factor structure of the CSDD among Ja...

journal_title：International journal of geriatric psychiatry

authors： Schreiner AS,Morimoto T

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:We hypothesize that the personality influences the caregiver's depression, burden and distress related to BPSD. SUBJECTS AND METHODS:Participants were 105 consecutive patients with dementia and their family caregivers, living at home, attending a Dementia Clinic. A cross-sectional design was used with an app...

journal_title：International journal of geriatric psychiatry

authors： Melo G,Maroco J,de Mendonça A

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:To review and summarise published data on medication errors in older people with mental health problems. METHODS:A systematic review was conducted to identify studies that investigated medication errors in older people with mental health problems. MEDLINE, EMBASE, PHARMLINE, COCHRANE COLLABORATION and PsycIN...

journal_title：International journal of geriatric psychiatry

authors： Maidment ID,Haw C,Stubbs J,Fox C,Katona C,Franklin BD

更新日期：2008-06-01 00:00:00

abstract：:This review presents evidence of the undertreatment of pain for people with cognitive impairment and explores reasons for this, emphasizing inadequate detection due to lack of suitable pain assessment protocols. Implications for practice and suggestions for further research are made. ...

journal_title：International journal of geriatric psychiatry

authors： Cook AK,Niven CA,Downs MG

更新日期：1999-06-01 00:00:00

abstract：:This cross-sectional study explored age-related differences in the frequency of diagnosis of personality disorder (PD) among 790 veterans admitted to a psychiatric inpatient unit across three age groups: 20-39, 40-59, and 60+. Older adults obtained a lower frequency (55.4%) of PD diagnosis than middle-aged adults (69....

journal_title：International journal of geriatric psychiatry

authors： Kenan MM,Kendjelic EM,Molinari VA,Williams W,Norris M,Kunik ME

更新日期：2000-09-01 00:00:00

abstract：OBJECTIVE:To determine whether older primary care patients with a Major Depressive Disorder (MDD) have lower heart rate variability (HRV) compared to non-depressed patients. HRV is a measure of cardiac autonomic functioning. METHOD:A cross-sectional comparison of 136 elderly persons with MDD and 136 non-depressed cont...

journal_title：International journal of geriatric psychiatry

authors： van der Kooy KG,van Hout HP,van Marwijk HW,de Haan M,Stehouwer CD,Beekman AT

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Alzheimer's disease (AD) is associated with both cognitive and behavioral symptoms. Agitation, hallucinations, delusions, aggression, irritability, and anxiety are observed in up to 90% of patients with dementia. Although new information has emerged in recent years on the treatment of psychosis and agitation...

journal_title：International journal of geriatric psychiatry

authors： Mintzer J,Faison W,Street JS,Sutton VK,Breier A

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:This paper investigates the potential effects of a policy change in the funding of UK residential care. The White Paper Modernising Social Services (Cm 4169, 1998) outlined plans to change the distribution of the Residential Allowance (RA), payable in support of residents in independent residential or nursin...

journal_title：International journal of geriatric psychiatry

authors： Clarkson P,Hughes J,Challis D

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:Apathy is one of the most frequent symptoms of dementia, whose underlying neurobiology is not well understood. The objective was to analyze the correlations of apathy and its dimensions with gray and white matter damage in the brain of patients with advanced Alzheimer's disease (AD). METHODS:The setting of t...

journal_title：International journal of geriatric psychiatry

authors： Agüera-Ortiz L,Hernandez-Tamames JA,Martinez-Martin P,Cruz-Orduña I,Pajares G,López-Alvarez J,Osorio RS,Sanz M,Olazarán J

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to examine whether the reversal of compromised regional cerebral blood flow (rCBF) in older patients with major depressive disorder (MDD) is dependent on specific parameters of selective serotonin reuptake inhibitor (SSRI) treatment and to examine the efficacy of such treatment. ...

journal_title：International journal of geriatric psychiatry

authors： Hanada H,Imanaga J,Yoshiiwa A,Yoshikawa T,Tanaka Y,Tsuru J,Inoue A,Ishitobi Y,Okamoto S,Kanehisa M,Maruyama Y,Ninomiya T,Higuma H,Isogawa K,Kawasaki T,Fujioka T,Akiyoshi J

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. METHODS:Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital or visiting a day-clinic between 2000 and 2010. Patients were divided in those with and without a...

journal_title：International journal of geriatric psychiatry

authors： van de Vorst IE,Vaartjes I,Bots ML,Koek HL

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Dementia is a rapidly growing problem in all parts of the developing world. Such societies are characterised by low levels of awareness regarding dementia as a chronic degenerative brain syndrome, and by an absence of supportive health and welfare services. There is reliance upon families as the cornerstone ...

journal_title：International journal of geriatric psychiatry

authors： Shaji KS,Smitha K,Lal KP,Prince MJ

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:To examine the contribution of medication adherence to 12-month depression scores in the context of other psychosocial and clinical predictors of depression in a sample of older adults treated for depression. METHODS:Secondary analysis of a prospective cohort study involving 241 older patients undergoing dep...

journal_title：International journal of geriatric psychiatry

authors： Bosworth HB,Voils CI,Potter GG,Steffens DC

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:Studies have shown that psychological problems in elderly patients are often unrecognised in primary care. The aim of this study was to investigate the quality of life and consultation rates of Chinese elderly patients with unrecognised psychological problems in primary care. The prevalence and risk factors o...

journal_title：International journal of geriatric psychiatry

authors： Lam CL,Chin WY,Lee PW,Lo YY,Fong DY,Lam TP

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVE:To review non-drug treatments for dementia; to provide a source of evidence for informal carers who want ideas about non-drug approaches for dementia, that they might try or that they could try to access. The systematic review addresses: what non-drug treatments work and what do they work for? What non-drug t...

journal_title：International journal of geriatric psychiatry

authors： Hulme C,Wright J,Crocker T,Oluboyede Y,House A

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVE:Evidence in younger populations suggests quantitative but not categorical differences in cognitive impairments between schizophrenia and bipolar disorder. It is uncertain whether a similar distinction applies to patients in later life. METHODS:We compared the cognitive abilities of older, community-living sc...

journal_title：International journal of geriatric psychiatry

authors： Meesters PD,Schouws S,Stek M,de Haan L,Smit J,Eikelenboom P,Beekman A,Comijs H

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:T2 white matter hyperintensity (WMH) on magnetic resonance imaging (MRI) is associated with brain atrophy. Some previous studies examined the relation between the WMH and cortical atrophy, however, little is known about how the WMHs affect the pattern of cortical atrophy. Recent studies have revealed that pat...

journal_title：International journal of geriatric psychiatry

authors： Ota M,Nemoto K,Sato N,Mizukami K,Yamashita F,Asada T

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The aim of this study is to examine the hypotheses stating the importance of amyloid or of its oligomers in the pathogenesis of Alzheimer's disease (AD). METHODS:Published studies were examined. RESULTS:The importance of amyloid in the pathogenesis of AD is well established, yet accepting it as the main cau...

journal_title：International journal of geriatric psychiatry

authors： Fessel J

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Hoarding disorder (HD) is a chronic and debilitating psychiatric condition. Midlife HD patients have been found to have neurocognitive impairment, particularly in areas of executive functioning, but the extent to which this is due to comorbid psychiatric disorders has not been clear. AIMS/METHOD:The purpose...

journal_title：International journal of geriatric psychiatry

authors： Ayers CR,Wetherell JL,Schiehser D,Almklov E,Golshan S,Saxena S

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:to investigate the suicide phenomenon among the elderly (people aged 65 and over) in the Italian provinces of Novara and Verbania, in the time span between January 1990 and December 2000, in order to evaluate if the characteristics of the suicide behaviour correlate to the place of living with particular att...

journal_title：International journal of geriatric psychiatry

authors： Zeppegno P,Manzetti E,Valsesia R,Siliquini R,Ammirata G,De Donatis O,Usai C,Torre E

更新日期：2005-08-01 00:00:00

abstract：OBJECTIVES:To investigate the structure and measurement properties of the Psychogeriatric Assessment Scales (PAS) in a community sample, to study the performance of French and German translations of the PAS, and to determine the power of PAS scales to discriminate dementia and depression diagnosed to DSM-IV criteria. D...

journal_title：International journal of geriatric psychiatry

authors： Mackinnon A,Mulligan R

更新日期：2001-09-01 00:00:00