Abstract：
BACKGROUND:Vascular depression is an important conceptual and clinical concept. OBJECTIVE:To apply criteria which, in an ideal world, should be satisfied before an association between depression and vascular disease can be considered robust. METHOD:A literature review with discussion of findings in the light of recently suggested guidelines for the development of new psychiatric disorders. RESULTS:There is considerable evidence linking depression in later life with vascular brain disease but the interaction is bi-directional. Depression and vascular disease could be mediated by factors other than traditional vascular risk factors. There is increasing interest in mechanisms such as inflammatory processes which may mediate both depression and vascular disease. CONCLUSIONS:Vascular depression provides a useful framework with which to remind the clinician of important interactions between depression and vascular disease but conceptually it may be too restrictive.
journal_name
Int J Geriatr Psychiatryjournal_title
International journal of geriatric psychiatryauthors
Baldwin RCdoi
10.1002/gps.1255subject
Has Abstractpub_date
2005-01-01 00:00:00pages
1-11issue
1eissn
0885-6230issn
1099-1166journal_volume
20pub_type
杂志文章,评审abstract：BACKGROUND:The mini-mental state exam (MMSE) has been used to address questions such as determination of appropriate cutoff scores for differentiation of individuals with intact cognitive function from patients with dementia and rate of cognitive decline. However, little is known about the relationship of performance i...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2282
更新日期：2009-12-01 00:00:00
abstract：OBJECTIVE:The study objective is to evaluate the use of qEEG data for the cross-sectional differentiation of mild cognitive impairment (MCI) from mild Alzheimer's disease (AD) and in the longitudinal prediction of cognitive decline in MCI. METHODS:Eighty-eight subjects with MCI and 42 subjects with mild probable AD we...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2042
更新日期：2008-11-01 00:00:00
abstract：OBJECTIVES:This study investigated cognitive impairment in late-life depression in a follow-up design. The main objective was to assess the most important cognitive domains implicated in late-life depression, in patients who underwent pharmacological treatment, in the acute phase and twelve months after. METHODS:Neuro...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.895
更新日期：2003-07-01 00:00:00
abstract：:Wolf-Klein and colleagues' clock drawing test (CDT) performance was compared with Pfeiffer's Short Portable Mental Status Questionnaire (Pfeiffer) scores in 145 outpatient geropsychiatry patients. Although normal CDT results were almost always associated with normal Pfeiffer scores, 21% of Pfeiffer normal individuals ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/(sici)1099-1166(199705)12:5<526::aid-gps53
更新日期：1997-05-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to evaluate the effect of tumour necrosis factor-alpha inhibitors (TNF-αI) on Alzheimer's disease-associated pathology. DESIGN:A literature search of PubMed, Embase, PsychINFO, Web of Science, Scopus, and the Cochrane Library databases for human and animal studies that evalua...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4871
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Depression is a frequent problem in stroke patients but, all too often, the problem goes unrecognized. How depression-like symptoms in post-stroke depression (PSD) should be interpreted is still subject to debate. If PSD has a distinct symptom profile of depression accompanying other chronic vascular somatic...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2236
更新日期：2009-10-01 00:00:00
abstract：OBJECTIVE:The objective of this pilot study was to gather preliminary evidence on suicidal ideation in family carers of people with dementia. METHODS:An online, cross-sectional survey was conducted with 120 family carers, the majority of whom were located in Australia and USA. The survey included measures of suicidali...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.3941
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVES:This integrative review aimed to synthesize studies that investigated the effects of acupressure on sleep quality, depression, anxiety, and agitation in older people, and to describe the acupressure procedures and techniques applied in the included studies. METHODS:A literature search was conducted using el...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5031
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:Minor stroke is characterized by mild neurological functional impairment and relatively good outcome. Little is known about the association between post-stroke depression (PSD) and outcomes of minor stroke. The aim of this study was to investigate the association between PSD and disability and quality of life...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4353
更新日期：2016-04-01 00:00:00
abstract：OBJECTIVES:Little is known about the use of antidementia medications in Australia. Other countries have reported sociodemographic disparities in use. Our objective was to estimate prevalence, duration, and time to initiation of antidementia medication (cholinesterase inhibitors or memantine) among Australians with deme...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5105
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the impact of cardiovascular disease (CVD) on mortality and readmission risk in patients with dementia. METHODS:Prospective hospital-based cohort of 59 194 patients with dementia admitted to hospital or visiting a day-clinic between 2000 and 2010. Patients were divided in those with and without a...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5044
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:To identify carer and patient characteristics associated with various aspects of burden of care. METHOD:The burden on 196 carers, each caring for one patient with dementia, was rated by means of the Relative Stress Scale (RSS). Patients were assessed with the Mini Mental State Examination (MMSE), the Disabil...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1654
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To derive norms for the Mini Mental State Examination (MMSE) based on age, gender and level of formal education among the elderly in Sri Lanka. METHOD:A validated Sinhalese version of the MMSE was administered to people aged 55 years and above residing in 14 randomly selected elders' homes. Effects of age, g...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2168
更新日期：2009-07-01 00:00:00
abstract：OBJECTIVE:To review non-drug treatments for dementia; to provide a source of evidence for informal carers who want ideas about non-drug approaches for dementia, that they might try or that they could try to access. The systematic review addresses: what non-drug treatments work and what do they work for? What non-drug t...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.2429
更新日期：2010-07-01 00:00:00
abstract：OBJECTIVE:Mild cognitive impairment in Parkinson's disease (PD-MCI) has been suggested to be a predictor for the development of PD dementia (PDD). This study explored the incidence and possible neuropsychological domain differences between PD patients with PD-MCI and without cognitive impairment (normal cognitive funct...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4261
更新日期：2015-10-01 00:00:00
abstract：OBJECTIVES:Late-life depression (LLD) is the association with more cerebrovascular susceptibilities and white matter damage that can be assessed with diffusion tensor imaging (DTI). To better understand the white matter pathological alterations in LLD, we conducted a systematic review and meta-analysis. METHODS:We sea...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,meta分析,评审
doi：10.1002/gps.4129
更新日期：2014-12-01 00:00:00
abstract：OBJECTIVES:The pattern of neural damage in dementia with Lewy Bodies (DLB) led us to hypothesize that patients with DLB would be particularly impaired on parallel ('pop-out') search tasks, relative to serial search tasks, and that this would serve to distinguish DLB from other forms of neurodegenerative disease, partic...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1159
更新日期：2004-08-01 00:00:00
abstract：OBJECTIVES:An increasing evidence suggests hypertension (HTN) could be linked to cognitive impairment and incident Alzheimer's disease (AD). The precise mechanisms linking HTN and AD are not well-known. The aim of this study was to assess the putative association between HTN and AD. METHODS:We assessed in patients wit...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5366
更新日期：2020-11-01 00:00:00
abstract：OBJECTIVE:To describe the treatment of vocally disruptive behaviour (VDB) of multifactorial aetiology. METHOD:Three case reports were used to illustrate the treatment of multifactorial VDB. RESULTS:A biopsychosocial assessment is required to identify the different aetiologies involved and the way they interact. Acute...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：OBJECTIVE:We investigated cognitive dysfunction in patients with Alzheimer's disease (AD) and amnestic mild cognitive impairment (aMCI) who present hemispheric asymmetries of cerebral metabolic rate of glucose (CMRglc) decrease on (18) F-fluorodeoxyglucose positron emission tomography. METHODS:Based on the hemispheric...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4287
更新日期：2016-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study is to examine the hypotheses stating the importance of amyloid or of its oligomers in the pathogenesis of Alzheimer's disease (AD). METHODS:Published studies were examined. RESULTS:The importance of amyloid in the pathogenesis of AD is well established, yet accepting it as the main cau...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.4730
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:To investigate the relation of plasma levels of Abeta peptides (Abeta1-40 and Abeta1-42) and apolipoprotein E (APOE) genotype to dementia status, and the duration of Alzheimer's disease (AD) in adults with Down syndrome (DS). METHODS:Adults with DS were recruited from community settings and followed up for ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2321
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:This study examined changes in cognitive-functional relationships in vascular dementia (VaD) over the course of one year. METHODS:Twenty-four patients with probable VaD were administered the Dementia Rating Scale (DRS). Caregivers completed an informant-based measure of instrumental (IADL) and basic activit...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.1556
更新日期：2006-08-01 00:00:00
abstract：OBJECTIVE:The objective of the study is to assess combined antidepressant and memantine treatment in older patients presenting with depression and cognitive impairment. METHODS:Thirty-five depressed patients with cognitive impairment participated in this open-label pilot study. We evaluated whether, over a 48-week per...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4375
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVES:Depression in late life has been associated with difficulties in cognitive processing, particularly in the domains of executive function, processing speed and memory, and increases the risk of developing dementia suggesting a neurodegenerative phenotype. Mitochondrial dysfunction is frequently an early event...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4439
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVES:To measure two forms of attrition in a cohort of volunteer brain donors: Withdrawal during life and non-donation at death. To test whether cognitive impairment independently predicts attrition. METHOD:Attrition rates were calculated for all registered participants and for all brain donors who had completed ...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4975
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVES:Describe novel methods for ascertaining verbal fluency in a large national sample of adults, examine demographic factors influencing performance, and compare scores to studies using in-person assessment. METHODS/DESIGN:Participants were from the Reasons for Geographic and Racial Differences in Stroke (REGAR...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.5054
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:This study examined the associations of personality characteristics with both subtypes and symptom dimensions of depression in older adults. METHODS:Three hundred and seventy-eight depressed older adults participated in the Netherlands Study of Depression in Older Persons. Personality characteristics were as...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.4670
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:T2 white matter hyperintensity (WMH) on magnetic resonance imaging (MRI) is associated with brain atrophy. Some previous studies examined the relation between the WMH and cortical atrophy, however, little is known about how the WMHs affect the pattern of cortical atrophy. Recent studies have revealed that pat...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章
doi：10.1002/gps.2618
更新日期：2011-09-01 00:00:00
abstract：BACKGROUND:The paper explores the diverse ethical issues in the care of persons with dementia, in the Netherlands and Kerala, India. These cross-cultural data are used to suggest newer ways for addressing the ethical issues in a mutually enhancing manner. METHODS:A thorough review of the literature focusing on ethical...
journal_title：International journal of geriatric psychiatry
pub_type： 杂志文章,评审
doi：10.1002/gps.2127
更新日期：2009-04-01 00:00:00
