Abstract：
:Biomagnetic measurements are based on the noninvasive recording of magnetic signals produced by biological sources such as nervous system and muscle. The aim of this study was to obtain multichannel magnetic field recordings from the human gastrointestinal tract and to localize the sources of these signals three-dimensionally. The magnetic field was recorded in eight human healthy subjects using a sensor array with 37 superconducting quantum interference devices (SQUIDs); an electrogastrogram was recorded simultaneously. Biomagnetic source localization was carried out with an iterative nonlinear optimization algorithm using the model of an equivalent current dipole (ECD) and correlated to magnetic resonance imaging (MRI) in four volunteers. Magnetogastrograms and electrogastrograms demonstrated a similar frequency distribution with a peak at 3/min. In all subjects the centers of the calculated dipoles plotted vs time showed a characteristic migration across the stomach area. One volunteer demonstrated tachygastric episodes, during which his magnetic field amplitudes increased fivefold and his dipole migration disappeared. In absence of an attack his recordings changed to normal. This demonstrates multichannel magnetic recordings can be used to localize the sources of the biomagnetic field, which could be useful for the understanding of motility disturbances.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Allescher HD,Abraham-Fuchs K,Dunkel RE,Classen Mdoi
10.1023/a:1018852208687subject
Has Abstractpub_date
1998-04-01 00:00:00pages
683-93issue
4eissn
0163-2116issn
1573-2568journal_volume
43pub_type
杂志文章abstract：BACKGROUND:Metabolic syndrome contributing to nonalcoholic fatty liver disease (NAFLD) can lead to hepatic dysfunction, steatohepatitis, cirrhosis, and hepatocellular carcinoma. AIMS:In this study, we tested whether diet-induced fatty liver in a mouse model physiologically mimicked human NAFLD, and whether transcripti...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-018-5398-4
更新日期：2019-05-01 00:00:00
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journal_title：Digestive diseases and sciences
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doi：10.1007/s10620-007-9869-2
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abstract：:Longitudinal shortening of the esophagus during peristaltic contraction has been previously analyzed globally using spaced mucosal clips. This method gives a relatively crude measurement. In this study, local longitudinal shortening (LLS) was evaluated using simultaneous high-resolution endoluminal ultrasound (HREUS) ...
journal_title：Digestive diseases and sciences
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doi：10.1007/s10620-006-3092-4
更新日期：2006-01-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,meta分析
doi：10.1007/BF02088245
更新日期：1996-06-01 00:00:00
abstract：:We have developed an improved semiconductor recording probe for monitoring motility of the upper small intestine in humans. The probe consists of six ultraminiature silicon pressure sensors spaced 10 cm apart and encased in a flexible polyurethane sheath. The probe is small [2.67 mm (8F) diameter], is easily passed tr...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308196
更新日期：1985-02-01 00:00:00
abstract：BACKGROUND:The relationship of gastric cancer to the presence of interleukin-8 (IL-8) 251 T/A has been reported with conflicting results. AIM:To further explore the association of IL-8 251 allele polymorphism with gastric cancer susceptibility. METHODS:We performed an extensive search of relevant studies and carried ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,meta分析,评审
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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journal_title：Digestive diseases and sciences
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doi：10.1023/a:1026605409557
更新日期：1998-11-01 00:00:00
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journal_title：Digestive diseases and sciences
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更新日期：2005-12-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-3163-6
更新日期：2006-03-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
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更新日期：2005-12-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-2934-9
更新日期：2005-10-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-017-4589-8
更新日期：2017-06-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026658301825
更新日期：1999-01-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1697-8
更新日期：2011-10-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02209007
更新日期：1995-10-01 00:00:00
abstract：:The role of carbonic anhydrase in the process of proximal duodenal mucosal bicarbonate secretion was investigated in the guinea pig. In a series of experiments in vivo, the duodenum was perfused with 24 mmol/liter NaHCO3 solution (+ NaCl for isotonicity) to ensure that active duodenal HCO3- secretion against a concent...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02087561
更新日期：1994-05-01 00:00:00
abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-012-2526-4
更新日期：2013-06-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3512-9
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journal_title：Digestive diseases and sciences
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doi：10.1023/a:1011982024849
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abstract：:Nearly all chronic anal fissures occur in the posterior midline of the anal canal. However, some of them are in the anterior midline and are rarely double or in the lateral anal walls. The aim of this study was to determine if the clinical, manometric and endosonographic characteristics in patients with chronic anal f...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
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更新日期：2008-01-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-013-2969-2
更新日期：2014-04-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308431
更新日期：1979-03-01 00:00:00
abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536381
更新日期：1989-07-01 00:00:00
abstract：:Hepatitis B virus (HBV) infection is a major etiology of chronic liver disease worldwide. In the past decade, nonalcoholic fatty liver disease (NAFLD) has emerged as a common liver disorder in general population. Accordingly, the patient number of chronic hepatitis B (CHB) concomitant with NAFLD grows rapidly. The pre...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-015-3772-z
更新日期：2015-12-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-3835-1
更新日期：2016-01-01 00:00:00
abstract：:Forty-one (98%) of 42 patients with achalasia of the esophagus had pneumatic dilatation performed successfully using the Brown-McHardy dilator. One to four dilatations (mean, 1.9) were done on each patient with inflation pressures of 8-15 psi (mean, 11.1 psi). Immediately after the procedure, all patients were examine...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01297184
更新日期：1987-09-01 00:00:00
abstract：:The morphine-Prostigmin test (MPT) has been advocated as a diagnostic test for identifying patients with papillary stenosis. We studied 14 patients referred for possible papillary stenosis with the MPT and ERCP sphincter of Oddi manometry. The response to the MPT (symptoms, serum amylase/lipase values) was evaluated b...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01299827
更新日期：1979-06-01 00:00:00
