Abstract：
:Down syndrome is caused by triplicate material of chromosome 21. The syndrome has a variable physical expression, but congenital cardiac defects, transient myelodysplasia of the newborn and duodenal atresia are highly specific for this chromosomal disorder. Routine health maintenance is important because infants and children with Down syndrome are more likely to have otitis media, thyroid disease, congenital cataracts, leukemoid reactions, dental problems and feeding difficulties. Since infants with this syndrome are prone to respiratory infections, immunization recommendations should be followed closely. Motor, language, social and adaptive skills should be assessed at each office visit. The psychosocial aspects of care should be discussed with the parents of an infant with Down syndrome. If necessary, the parents should be referred to family support and specialty resources. Institutionalization of infants with Down syndrome is now unlikely. With newer surgical techniques, early therapy to minimize developmental delay and proper health supervision, the functional prognosis for infants with Down syndrome is considerably improved.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Saenz RBsubject
Has Abstractpub_date
1999-01-15 00:00:00pages
381-90, 392, 395-6issue
2eissn
0002-838Xissn
1532-0650journal_volume
59pub_type
杂志文章,评审abstract：:A herpes zoster infection in patients with lymphoma has been associated with subsequent metastatic disease involving the spinal cord and vertebrae of the affected dermatome segment. This correlation can be used in planning radiation therapy to avert neurologic complications secondary to spinal cord involvement. ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-08-01 00:00:00
abstract：:Genital herpes affects over 30 million persons in the United States. Genital herpes has three distinct presenting syndromes, depending on the patient's immune status with regard to the herpes simplex virus. Current diagnostic strategy relies on clinical findings and the selective use of viral culture. Acyclovir is the...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:Industrial carbon tetrachloride is used in the synthesis of chlorofluorocarbons and chlorinated solvents. Although both production and use of carbon tetrachloride are declining, industrial and hazardous waste sites remain as sources of exposure. Workers using carbon tetrachloride or products that contain it are at hig...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:Burns are the second most common cause of death in childhood. More than half of pediatric burns are partial-thickness scald burns; the majority occur in the kitchen. Generally, minor burns may be treated on an outpatient basis, while moderate burns are treated in a community hospital. Children with major burns should ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1987-10-01 00:00:00
abstract：:Myasthenia gravis is characterized by variable ocular and skeletal muscle weakness. Peak incidence is in young women and older men. Thymomas are present in 30 percent of myasthenic patients over age 40. Binding of acetylcholine receptors by IgG antibodies may be the mechanism of the neuromuscular disorder. Repetitive ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-02-01 00:00:00
abstract：:Parkinson's disease is a common neurodegenerative disorder that can cause significant disability and decreased quality of life. The cardinal physical signs of the disease are distal resting tremor, rigidity, bradykinesia, and asymmetric onset. Levodopa is the primary treatment for Parkinson's disease; however, its lon...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-12-15 00:00:00
abstract：:Anemia in children is commonly encountered by the family physician. Multiple causes exist, but with a thorough history, a physical examination and limited laboratory evaluation a specific diagnosis can usually be established. The use of the mean corpuscular volume to classify the anemia as microcytic, normocytic or ma...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2001-10-15 00:00:00
abstract：:The incidence of malignant melanoma has increased in recent years more than that of any other cancer in the United States. About one in 70 people will develop melanoma during their lifetime. Family physicians should be aware that a patient with a changing mole, an atypical mole or multiple nevi is at considerable risk...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2001-04-01 00:00:00
abstract：:Slipped capital femoral epiphysis is the most common hip disorder in adolescents, and it has a prevalence of 10.8 cases per 100,000 children. It usually occurs in children eight to 15 years of age, and it is one of the most commonly missed diagnoses in children. Slipped capital femoral epiphysis is classified as stabl...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2010-08-01 00:00:00
abstract：:Problems resulting from cold exposure can be successfully treated when a coordinated emergency medical transport system and appropriate equipment are available, as well as medical personnel knowledgeable in the management of frostbite and hypothermia. Clinical suspicion of these disorders is essential. Profoundly hypo...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：:Acute bronchitis is one of the top 10 conditions for which patients seek medical care. Physicians show considerable variability in describing the signs and symptoms necessary to its diagnosis. Because acute bronchitis most often has a viral cause, symptomatic treatment with protussives, antitussives, or bronchodilator...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-15 00:00:00
abstract：:Arnold-Chiari malformation is a disorder of embryologic development. In Type I, there is cerebellar displacement into the spinal canal, but hydrocephalus and syringomyelia are variable. Type II usually is manifested by severe hydrocephalus and myelomeningocele in infancy. Type I malformations may pose diagnostic chall...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Frequent school absenteeism has immediate and long-term negative effects on academic performance, social functioning, high school and college graduation rates, adult income, health, and life expectancy. Previous research focused on distinguishing between truancy and anxiety-driven school refusal, but current policy ha...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2018-12-15 00:00:00
abstract：:Photosensitivity reactions associated with the use of prescription or over-the-counter drugs may be classified as phototoxic (caused by potentiation of solar energy by a drug) or photoallergic (in which the combination of a photosensitizing agent and light evokes a true cell-mediated hypersensitivity response). A case...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:The chief side effect of phenobarbital is drowsiness, which is usually associated with overdosage. Phenytoin, on the other hand, causes gingival hyperplasia in many patients, irreversible hypertrichosis in some patients and lethal reactions, such as Stevens-Johnson syndrome, in a few patients. Antiepileptic therapy sh...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-08-01 00:00:00
abstract：:Childhood bullying has potentially serious implications for bullies and their targets. Bullying involves a pattern of repeated aggression, a deliberate intent to harm or disturb a victim despite the victim's apparent distress, and a real or perceived imbalance of power. Bullying can lead to serious academic, social, e...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2004-11-01 00:00:00
abstract：:Acute bronchitis is a lower respiratory tract infection that causes reversible bronchial inflammation. In up to 95 percent of cases, the cause, is viral. While antibiotics are often prescribed for patients with acute bronchitis, little evidence shows that these agents provide significant symptomatic relief or shorten ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-03-15 00:00:00
abstract：:Prompt diagnosis and treatment of infectious arthritis can help prevent significant morbidity and mortality. The acute onset of monoarticular joint pain, erythema, heat, and immobility should raise suspicion of sepsis. Constitutional symptoms such as fever, chills, and rigors are poorly sensitive for septic arthritis....
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2011-09-15 00:00:00
abstract：:Idiopathic facial (Bell's) palsy is an affliction commonly seen and managed by the family physician. Although the prognosis is generally good, steroids and cromolyn sodium have each been advocated to enhance full recovery. Surgical exploration of the nerve is indicated when the diagnosis is unclear. Various measures m...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1989-08-01 00:00:00
abstract：:Transient organic causes of impotence include alcohol consumption, drug use or inflammatory genital disease. Many diagnoses of organic impotence, with diabetes, for example, have been premature and have resulted in iatrogenic, psychogenic impotence. After a stroke, heart attack or major surgery, depression may cause i...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:Microscopic hematuria, a common finding on routine urinalysis of adults, is clinically significant when three to five red blood cells per high-power field are visible. Etiologies of microscopic hematuria range from incidental causes to life-threatening urinary tract neoplasm. The lack of evidence-based imaging guideli...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2006-05-15 00:00:00
abstract：:Magnetic resonance imaging uses powerful magnetic fields and a radiofrequency pulse to provide a diagnostic image. Physicians must identify patients with metallic internal implants, pacemakers and cochlear implants before MRI scanning to prevent serious injury. Some patients also experience severe anxiety from the con...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Gout is a disease resulting from the deposition of urate crystals caused by the overproduction or underexcretion of uric acid. The disease is often, but not always, associated with elevated serum uric acid levels. Clinical manifestations include acute and chronic arthritis, tophi, interstitial renal disease and uric a...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-04-01 00:00:00
abstract：:The family physician is in a unique position to care for the total needs of the patient. Suggestion therapy and clinical hypnosis are helpful in managing the psychologic aspects of disease in all age groups beyond five years, and are well within the purview of family physicians. Learning these techniques can enhance t...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-06-01 00:00:00
abstract：:The protein-sparing modified fast is a safe and effective method for losing a large amount of weight relatively quickly. This diet should be used in combination with an exercise program, behavior modification and patient education. Caloric intake is in the range of 400 to 800 per day. Candidates for the diet should be...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1990-11-01 00:00:00
abstract：:Although a rare entity, laryngeal tuberculosis must be a diagnostic consideration--along with laryngeal carcinoma--whenever patients present with prolonged hoarseness or painful dysphagia. This form of tuberculosis was once thought to be especially virulent and more infectious than other forms; however, severity was p...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-09-01 00:00:00
abstract：:Nearly 40 percent of Americans complain about insomnia. Such complaints are even more common among the elderly, possibly because sleep efficiency decreases with age. As a result, the use of hypnotics in this age group is high--sometimes too high. Hypnotics can be addictive, and many have a low therapeutic index. The b...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
abstract：:Hydrofluoric acid is widely used in both industrial and household settings. The acid may cause insidious burns that can be very destructive. If the burns are not treated appropriately, the continued action of the free fluoride ion leads to liquefaction necrosis of the affected soft tissues, bony erosion and, ultimatel...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1992-04-01 00:00:00
abstract：:Delirium is characterized by a sudden deterioration in cognitive function and an inability to sustain attention. It is a medical emergency that occurs in more than 20 percent of hospitalized elderly patients. Misdiagnosis is common and contributes to high morbidity and mortality. Patients may present in hypoactive, hy...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-11-01 00:00:00
abstract：:Delirium is common in hospitalized older patients and may be a symptom of a medical emergency, such as hypoxia or hypoglycemia. It is characterized by an acute change in cognition and attention, although the symptoms may be subtle and usually fluctuate throughout the day. This heterogeneous syndrome requires prompt re...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2008-12-01 00:00:00
