Abstract：
:Gout is a disease resulting from the deposition of urate crystals caused by the overproduction or underexcretion of uric acid. The disease is often, but not always, associated with elevated serum uric acid levels. Clinical manifestations include acute and chronic arthritis, tophi, interstitial renal disease and uric acid nephrolithiasis. The diagnosis is based on the identification of uric acid crystals in joints, tissues or body fluids. Treatment goals include termination of the acute attack, prevention of recurrent attacks and prevention of complications associated with the deposition of urate crystals in tissues. Pharmacologic management remains the mainstay of treatment. Acute attacks may be terminated with the use of nonsteroidal anti-inflammatory agents, colchicine or intra-articular injections of corticosteroids. Probenecid, sulfinpyrazone and allopurinol can be used to prevent recurrent attacks. Obesity, alcohol intake and certain foods and medications can contribute to hyperuricemia. These potentially exacerbating factors should be identified and modified.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Pittman JR,Bross MHsubject
Has Abstractpub_date
1999-04-01 00:00:00pages
1799-806, 1810issue
7eissn
0002-838Xissn
1532-0650journal_volume
59pub_type
杂志文章,评审abstract：:Functional constipation is the cause of fecal incontinence in 95 percent of affected children, and anatomic or neurologic causes account for up to 5 percent of cases. The history and the physical examination (with emphasis on abdominal, rectal and neurologic examinations) are most helpful in identifying organic diseas...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:Family physicians should be aware of the potential effects and complications of vasectomy so they can appropriately counsel patients seeking sterilization. Vasectomy produces anatomic, hormonal and immunologic changes and, although not substantiated by clinical studies, has been reputed to be associated with atheroscl...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-15 00:00:00
abstract：:A biopsychosocial theory and approach to drug-seeking behavior suggests new questions for the family physician to ask his patient when psychotropic drugs are being considered. The theory and rational guidelines for prescribing allow the physician to make more appropriate decisions when faced with difficult situations....
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1979-01-01 00:00:00
abstract：:Patients who have been or may have been bitten by a snake should receive prompt and careful clinical and laboratory evaluation. Fang marks, pain and swelling are characteristic of pit viper envenomation. Although no therapy is universally accepted, a number of treatment plans appear to be effective. If envenomation ha...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-07-01 00:00:00
abstract：:Primary immunodeficiencies include a variety of disorders that render patients more susceptible to infections. If left untreated, these infections may be fatal. The disorders constitute a spectrum of more than 80 innate defects in the body's immune system. Primary immunodeficiencies generally are considered to be rela...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-11-15 00:00:00
abstract：:Vertigo is the illusion of motion, usually rotational motion. As patients age, vertigo becomes an increasingly common presenting complaint. The most common causes of this condition are benign paroxysmal positional vertigo, acute vestibular neuronitis or labyrinthitis, Ménière's disease, migraine, and anxiety disorders...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2005-03-15 00:00:00
abstract：:Adnexal masses can have gynecologic or nongynecologic etiologies, ranging from normal luteal cysts to ovarian cancer to bowel abscesses. Women who report abdominal or pelvic pain, increased abdominal size or bloating, difficulty eating, or rapid satiety that occurs more than 12 times per month in less than a year shou...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2016-04-15 00:00:00
abstract：:Allergic rhinitis commonly manifests for the first time in childhood or adolescence with seasonal or perennial sneezing, rhinorrhea, nasal congestion, and pruritus of the nose, eyes and throat. The nasal mucosa are pale blue and boggy, with a clear discharge. Patients should be instructed to avoid breathing tobacco sm...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-03-01 00:00:00
abstract：:Knee pain is a common presenting complaint with many possible causes. An awareness of certain patterns can help the family physician identify the underlying cause more efficiently. Teenage girls and young women are more likely to have patellar tracking problems such as patellar subluxation and patellofemoral pain synd...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-09-01 00:00:00
abstract：:Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used, but have risks associated with their use, including significant upper gastrointestinal tract bleeding. Older persons, persons taking anticoagulants, and persons with a history of upper gastrointestinal tract bleeding associated with NSAIDs are at especia...
journal_title：American family physician
pub_type： 杂志文章,实务指引
doi：
更新日期：2009-12-15 00:00:00
abstract：:Bordetella pertussis is a highly contagious bacterium known to cause pertussis (whooping cough) and is transmitted via airborne droplets. Although childhood vaccination has dramatically reduced reported pertussis cases, the incidence of the disease has increased over the past 20 years, most notably in previously immun...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-08-01 00:00:00
abstract：:Industrial carbon tetrachloride is used in the synthesis of chlorofluorocarbons and chlorinated solvents. Although both production and use of carbon tetrachloride are declining, industrial and hazardous waste sites remain as sources of exposure. Workers using carbon tetrachloride or products that contain it are at hig...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:As effective antipsychotic pharmacotherapy has become available, patients with schizophrenia are increasingly managed in an outpatient setting by primary care physicians. Pharmacotherapy is generally effective in treating "positive," or psychotic, symptoms and lessening the risks of relapse, but ineffective in improvi...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:Management of a wide variety of musculoskeletal conditions requires the use of a cast or splint. Splints are noncircumferential immobilizers that accommodate swelling. This quality makes splints ideal for the management of a variety of acute musculoskeletal conditions in which swelling is anticipated, such as acute fr...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2009-09-01 00:00:00
abstract：:The female athlete triad is defined as the combination of disordered eating, amenorrhea and osteoporosis. This disorder often goes unrecognized. The consequences of lost bone mineral density can be devastating for the female athlete. Premature osteoporotic fractures can occur, and lost bone mineral density may never b...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-06-01 00:00:00
abstract：:Medical problems associated with prematurity are frequently complex, and a multidisciplinary approach is often required. Some common problems include the following: (1) anemia, which can be reduced by iron supplementation, (2) cerebral palsy or mental retardation as a result of intraventricular hemorrhage or periventr...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1998-05-15 00:00:00
abstract：:Acute ankle injury, a common musculoskeletal injury, can cause ankle sprains. Some evidence suggests that previous injuries or limited joint flexibility may contribute to ankle sprains. The initial assessment of an acute ankle injury should include questions about the timing and mechanism of the injury. The Ottawa Ank...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-11-15 00:00:00
abstract：:Alopecia can be divided into disorders in which the hair follicle is normal but the cycling of hair growth is abnormal and disorders in which the hair follicle is damaged. Androgenetic alopecia is the most common cause of hair loss in women. Other disorders include alopecia areata, telogen effluvium, cicatricial alope...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-03-01 00:00:00
abstract：:Acute pancreatitis is a clinical syndrome characterized by midepigastric pain, nausea and vomiting. Numerous etiologies have been linked with this entity, principally alcoholism and biliary disease. Once the clinical suspicion of pancreatitis is confirmed, supportive therapy with intravenous hydration and close observ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1995-08-01 00:00:00
abstract：:Nitrates are frequently found in vegetables and ground water. Nitrate levels in ground water have increased over the past two decades because of the heightened use of nitrogenous fertilizers. Following ingestion, nitrates are converted to nitrites by fecal organisms. Nitrites are absorbed and form methemoglobin, which...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-07-01 00:00:00
abstract：:Delirium is characterized by a sudden deterioration in cognitive function and an inability to sustain attention. It is a medical emergency that occurs in more than 20 percent of hospitalized elderly patients. Misdiagnosis is common and contributes to high morbidity and mortality. Patients may present in hypoactive, hy...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-11-01 00:00:00
abstract：:The primary therapy for anaphylaxis is epinephrine, which should be stocked in the office in the appropriate dilution (1:1,000). Antihistamines and corticosteroids are useful adjunctive agents that may be given in the office. Patients with progressive or severe symptoms should be transferred immediately to a facility ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-09-01 00:00:00
abstract：:Arnold-Chiari malformation is a disorder of embryologic development. In Type I, there is cerebellar displacement into the spinal canal, but hydrocephalus and syringomyelia are variable. Type II usually is manifested by severe hydrocephalus and myelomeningocele in infancy. Type I malformations may pose diagnostic chall...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：:Diet is the single most significant risk factor for disability and premature death. Patients and physicians often have difficulty staying abreast of diet trends, many of which focus primarily on weight loss rather than nutrition and health. Recommending an eating style can help patients make positive change. Dietary p...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2018-06-01 00:00:00
abstract：:Necrotizing sialometaplasia is a benign inflammatory disease of salivary gland origin. Because of its clinical and histologic resemblance to squamous cell carcinoma, this disease must be recognized. The cause is unknown, but it may be related to oral trauma, tobacco use or inadequate blood supply. The lesion heals spo...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1983-02-01 00:00:00
abstract：:Antidepressant drugs are now an important component of the analgesic pharmacopeia. Their ability to relieve pain is independent of the presence of clinical depression, and their efficacy has been documented in the treatment of migraine and tension headaches, neuropathic pain and chronic pain syndromes, including those...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1985-02-01 00:00:00
abstract：:Preterm birth is a major cause of infant morbidity and mortality. Although studies have been complicated by problems of definition and methodology, certain strategies have the potential to reduce both the incidence and the impact of preterm birth. These strategies include accurate assessment of gestational age, educat...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-08-01 00:00:00
abstract：:The specific type of epilepsy must be identified. The history and the EEG provide the evidence. Drug selection is then based on the classification of the patient's epilepsy. Major drugs used in the management of epilepsy are phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide and valproic acid. The physic...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-10-01 00:00:00
abstract：:Systemic causes of leg edema include idiopathic cyclic edema, heart failure, cirrhosis, nephrosis and other hypoproteinemic states. Lymphedema may be primary, or secondary to neoplasm, lymphangitis, retroperitoneal fibrosis and, rarely (in the U.S.), filariasis. Thrombophlebitis and chronic venous insufficiency are no...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:The hemagglutinin and neuraminidase surface antigens of the influenza virus periodically undergo major or minor structural changes. These influence epidemiologic patterns and the composition of vaccine. Annual vaccination is recommended for individuals at increased risk of complications from lower respiratory tract in...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1980-01-01 00:00:00
