Abstract：
:Primary immunodeficiencies include a variety of disorders that render patients more susceptible to infections. If left untreated, these infections may be fatal. The disorders constitute a spectrum of more than 80 innate defects in the body's immune system. Primary immunodeficiencies generally are considered to be relatively uncommon. There may be as many as 500,000 cases in the United States, of which about 50,000 cases are diagnosed each year. Common primary immunodeficiencies include disorders of humoral immunity (affecting B-cell differentiation or antibody production), T-cell defects and combined B- and T-cell defects, phagocytic disorders, and complement deficiencies. Major indications of these disorders include multiple infections despite aggressive treatment, infections with unusual or opportunistic organisms, failure to thrive or poor growth, and a positive family history. Early recognition and diagnosis can alter the course of primary immunodeficiencies significantly and have a positive effect on patient outcome.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Cooper MA,Pommering TL,Korányi Ksubject
Has Abstractpub_date
2003-11-15 00:00:00pages
2001-8issue
10eissn
0002-838Xissn
1532-0650journal_volume
68pub_type
杂志文章,评审abstract：:A case of bilateral compression femoral neuropathy due to iliopsoas muscle hematomas during anticoagulant therapy is described. Diagnosis was confirmed with computed tomographic scan. The right hematoma was larger than the left and caused a more severe femoral neuropathy. The hematoma on the right side was surgically ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1991-12-01 00:00:00
abstract：:Postpartum hemorrhage, the loss of more than 500 mL of blood after delivery, occurs in up to 18 percent of births and is the most common maternal morbidity in developed countries. Although risk factors and preventive strategies are dearly documented, not all cases are expected or avoidable. Uterine atony is responsibl...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2007-03-15 00:00:00
abstract：:Exercise-induced bronchoconstriction describes the narrowing of the airway that occurs with exercise. More than 10 percent of the general population and up to 90 percent of persons previously diagnosed with asthma have exercise-induced bronchoconstriction. Common symptoms include coughing, wheezing, and chest tightnes...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2011-08-15 00:00:00
abstract：:Patients with variceal or other gastrointestinal hemorrhage require aggressive resuscitative measures and early diagnosis for optimal therapy. A number of nonsurgical endoscopic modalities, such as laser therapy, sclerotherapy, heater probe and electrocoagulation (monopolar or bipolar), are available to arrest and som...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1986-10-01 00:00:00
abstract：:Wide complex tachycardias are cardiac rhythm disorders with three or more consecutive beats, rates exceeding 100 beats per minute and a QRS duration of 120 msec (0.12 second) or greater. The width of the QRS complex should be verified in a number of leads, since the QRS complex often appears mistakenly narrower (i.e.,...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1996-10-01 00:00:00
abstract：:Nitrates are frequently found in vegetables and ground water. Nitrate levels in ground water have increased over the past two decades because of the heightened use of nitrogenous fertilizers. Following ingestion, nitrates are converted to nitrites by fecal organisms. Nitrites are absorbed and form methemoglobin, which...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-07-01 00:00:00
abstract：:Myocardial perfusion imaging with thallium-201 has been used extensively for many years in the evaluation of ischemic heart disease. It is a valuable adjunct to exercise treadmill testing and is especially helpful in evaluating cardiac perfusion in patients who have abnormal resting electrocardiograms, who are unable ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-01 00:00:00
abstract：:Treatment of eating disorders is difficult regardless of the methods employed. Pharmacologic management in anorexia nervosa and in bulimia nervosa is especially helpful when it is part of a multimodal treatment approach that includes individual, family and behavioral therapy. Care must be taken to guard against side e...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1988-05-01 00:00:00
abstract：:Chronic pancreatitis is the progressive and permanent destruction of the pancreas resulting in exocrine and endocrine insufficiency and, often, chronic disabling pain. The etiology is multifactorial. Alcoholism plays a significant role in adults, whereas genetic and structural defects predominate in children. The aver...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2007-12-01 00:00:00
abstract：:The diagnosis of sleep apnea should be considered when a patient complains of snoring and excessive daytime somnolence. Middle-aged obese men are at particular risk, although apnea can occur in women and the elderly, as well as in persons who are not obese. An overnight polysomnographic sleep study can reveal the degr...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1994-02-01 00:00:00
abstract：:Family physicians should be aware of the potential effects and complications of vasectomy so they can appropriately counsel patients seeking sterilization. Vasectomy produces anatomic, hormonal and immunologic changes and, although not substantiated by clinical studies, has been reputed to be associated with atheroscl...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-11-15 00:00:00
abstract：:Historically, osteopathic physicians have made an important contribution to the primary care workforce. More than one half of osteopathic physicians are primary care physicians, and most of these are family physicians. However, the proportion of osteopathic students choosing family medicine, like that of their allopat...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：2005-08-15 00:00:00
abstract：:Thyroiditis is a spectrum of diseases that includes acute, subacute and chronic thyroiditis, all of which demonstrate the histologic findings of inflammation, fibrosis or lymphocytic infiltration. Acute thyroiditis is an infectious disease characterized by the abrupt onset of anterior neck pain and swelling. Subacute ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-15 00:00:00
abstract：:Patients with type 2 diabetes (formerly known as non-insulin-resistant diabetes) have a significantly increased risk of developing cardiovascular disease. Once clinical cardiovascular disease develops, these patients have a poorer prognosis than normoglycemic patients. By inducing endothelial changes, hyperglycemia co...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2000-12-15 00:00:00
abstract：:Left ventricular hypertrophy is more common in hypertensive individuals than in normotensive persons. Its presence in hypertensive patients is associated with an increased incidence of ventricular arrhythmias, myocardial infarction, congestive heart failure, stroke and cardiovascular mortality. Echocardiography is mor...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-08-01 00:00:00
abstract：:House calls can still serve many functions in the overall care of the patient. By improving the relationship between physician and patient, providing the physician with important information that can only be gained from a home visit and allowing the physician to remain active in the care of the homebound patient, hous...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1991-11-01 00:00:00
abstract：:Pressure sore are caused by multiple mechanisms. Preventive management requires relief of pressure, skin care, control of spasms, release of contractures and treatment of infection. Conservative treatment succeeds only when pressure on the ulcer site is relieved. Surgical treatment involves primary, secondary and tert...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1982-02-01 00:00:00
abstract：:Status epilepticus is an increasingly recognized public health problem in the United States. Status epilepticus is associated with a high mortality rate that is largely contingent on the duration of the condition before initial treatment, the etiology of the condition, and the age of the patient. Treatment is evolving...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2003-08-01 00:00:00
abstract：:Orthostatic hypotension is defined as a decrease of at least 20 mm Hg in systolic blood pressure when an individual moves from a supine position to a standing position. Nonneurogenic causes of orthostatic hypotension are related to cardiac pump failure, reduced intravascular volume, venous pooling or a medication side...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1997-10-01 00:00:00
abstract：:Zidovudine is now used extensively in an effort to control infection with the human immunodeficiency virus (HIV). The drug is associated with major hematologic toxicity, especially anemia and granulocytopenia. Conservative management of hematologic toxicity includes dosage reduction or cessation of therapy, diagnosis ...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
abstract：:Legionella pneumophila is transmitted by aerosolization of water or dust from soil. There are six serotypes and four newly recognized related organisms. Sporadic cased of Legionnaires; disease are more common than epidemic case and are less likely to be suspected . Most reporters cases are characterized by severe pneu...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
abstract：:Health literacy includes a set of skills needed to make appropriate health decisions and successfully navigate the health care system. These skills include reading, writing, numeracy, communication, and, increasingly, the use of electronic technology. National data indicate that more than one-third of U.S. adults have...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2015-07-15 00:00:00
abstract：:Cirrhosis is a diffuse process characterized by fibrosis and the conversion of normal liver architecture into structurally abnormal nodules. The modified Child-Pugh score, which ranks the severity of cirrhosis based on signs and liver function test results, has been shown to predict survival. Strategies have been esta...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2001-11-15 00:00:00
abstract：:Transient organic causes of impotence include alcohol consumption, drug use or inflammatory genital disease. Many diagnoses of organic impotence, with diabetes, for example, have been premature and have resulted in iatrogenic, psychogenic impotence. After a stroke, heart attack or major surgery, depression may cause i...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1978-02-01 00:00:00
abstract：:Appropriate dosage of levothyroxine for the treatment of hypothyroidism is assessed by determining the serum thyroxine (T4) concentration in secondary and tertiary types. In primary hypothyroidism, the optimal thyroid replacement is that which induces a normal thyroid-stimulating hormone level and a normal TSH respons...
journal_title：American family physician
pub_type： 杂志文章
doi：
更新日期：1982-09-01 00:00:00
abstract：:Health promotion activities benefit the elderly as much as they benefit younger persons. Motor vehicle accident and pedestrian injuries can be reduced by encouraging seat belt use and identifying unsafe drivers. Both medical and environmental factors should be considered in the prevention of falls in the elderly. All ...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1992-05-01 00:00:00
abstract：:Family physicians can treat most finger fractures and dislocations, but when necessary, prompt referral to an orthopedic or hand surgeon is important to maximize future function. Examination includes radiography (oblique, anteroposterior, and true lateral views) and physical examination to detect fractures. Dislocatio...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2006-03-01 00:00:00
abstract：:Tension-type headache typically causes pain that radiates in a band-like fashion bilaterally from the forehead to the occiput. Pain often radiates to the neck muscles and is described as tightness, pressure, or dull ache. Migraine-type features (unilateral, throbbing pain, nausea, photophobia) are not present All pati...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2002-09-01 00:00:00
abstract：:Kernicterus and neurologic sequelae caused by severe neonatal hyperbilirubinemia are preventable conditions. A structured and practical approach to the identification and care of infants with jaundice can facilitate prevention, thus decreasing rates of morbidity and mortality. Primary prevention includes ensuring adeq...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：2008-05-01 00:00:00
abstract：:Ischemic heart disease is one of the most common disorders managed by family physicians. Stratifying patients according to risk is important early in the course of the disease to identify patients who require invasive (percutaneous or surgical) treatment. Physical examination, clinical history, noninvasive tests and a...
journal_title：American family physician
pub_type： 杂志文章,评审
doi：
更新日期：1999-12-01 00:00:00
