Alzheimer's disease: making the diagnosis.

Abstract:

:Alzheimer's disease accounts for about 60 percent of dementia cases. Misdiagnosis of the treatable dementias can have devastating results. Pseudodementia accompanying major depression and chronic cognitive dysfunction due to psychoactive drugs are among the most commonly missed diagnoses. Although cortical atrophy is regularly found on computed tomographic scans in Alzheimer's disease, it is not necessarily diagnostic. A relatively distinct onset of cognitive impairment is not characteristic of Alzheimer's disease.

journal_name

Am Fam Physician

authors

Black KS,Hughes PL

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

196-202

issue

5

eissn

0002-838X

issn

1532-0650

journal_volume

36

pub_type

杂志文章
  • Diagnosis of acute stroke.

    abstract::Stroke can be categorized as ischemic stroke, intracerebral hemorrhage, or subarachnoid hemorrhage. Awakening with or experiencing the abrupt onset of focal neurologic deficits is the hallmark of the diagnosis of ischemic stroke. The most common presenting symptoms of ischemic stroke are speech disturbance and weaknes...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Yew KS,Cheng EM

    更新日期:2015-04-15 00:00:00

  • Health promotion in the elderly.

    abstract::Health promotion activities benefit the elderly as much as they benefit younger persons. Motor vehicle accident and pedestrian injuries can be reduced by encouraging seat belt use and identifying unsafe drivers. Both medical and environmental factors should be considered in the prevention of falls in the elderly. All ...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Carethers M

    更新日期:1992-05-01 00:00:00

  • Growth hormone therapy.

    abstract::Growth hormone from human pituitary glands has been available for 30 years. Because of the scarce supply and the danger of transmitting Creutzfeldt-Jakob disease, use of the hormone was discontinued in 1984. Fortunately, synthetic growth hormone produced with recombinant DNA technology became available in 1985 and eli...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Shulman L,Miller JL,Rose LI

    更新日期:1990-05-01 00:00:00

  • Initial evaluation, diagnosis, and treatment of anorexia nervosa and bulimia nervosa.

    abstract::Eating disorders are life-threatening conditions that are challenging to address; however, the primary care setting provides an important opportunity for critical medical and psychosocial intervention. The recently published Diagnostic and Statistical Manual of Mental Disorders, 5th ed., includes updated diagnostic cr...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Harrington BC,Jimerson M,Haxton C,Jimerson DC

    更新日期:2015-01-01 00:00:00

  • Anergy and delayed hypersensitivity skin testing.

    abstract::Delayed hypersensitivity skin tests, when properly planned and performed, are both practical and sensitive in determining the status of cell-mediated immunity. They can be diagnostic of specific exposure, such as tuberculosis, or they can rule out anergy. Pitfalls include poor selection of antigens, inappropriate appl...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Vinson WM

    更新日期:1983-05-01 00:00:00

  • Diagnosis and management of multiple sclerosis.

    abstract::Multiple sclerosis, an idiopathic inflammatory disease of the central nervous system, is characterized pathologically by demyelination and subsequent axonal degeneration. The disease commonly presents in young adults and affects twice as many women as men. Common presenting symptoms include numbness, weakness, visual ...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Calabresi PA

    更新日期:2004-11-15 00:00:00

  • Herpes esophagitis in immunocompetent patients.

    abstract::Although herpes simplex virus is a recognized cause of esophagitis in immunocompromised patients, it may also be the etiologic agent in otherwise healthy individuals. Odynophagia and dysphagia are the major symptoms. The esophagogram may reveal ulcers in the distal esophagus and there may be motor disturbances as well...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Ginaldi S,Burgert W Jr,Paulk HT Jr

    更新日期:1987-07-01 00:00:00

  • De Quervain's disease.

    abstract::This is a tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons contained within the osseofibrous tunnel of the distal radius. Multiple tendons for the abductor pollicis longus and a separate, severely narrowed sheath for the extensor pollicis brevis make nonsurgical treatment difficult at...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Field JH

    更新日期:1979-07-01 00:00:00

  • Subclinical hypothyroidism: deciding when to treat.

    abstract::While screening patients for thyroid disease, physicians often find increased thyrotropin-stimulating hormone (TSH) levels in patients whose free thyroxine (T4) levels are not below normal. This state, termed "subclinical hypothyroidism," is most commonly an early stage of hypothyroidism. Although the condition may re...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Adlin V

    更新日期:1998-02-15 00:00:00

  • Clues to cancer risk: biologic markers.

    abstract::Two large kindreds manifesting the "cancer family syndrome" have been studied. Genetic and biologic studies reveal markers which have important implications for cancer detection, control and prevention. Valuable markers may be found in the major histocompatibility system, HL-A. The presence of carcinoembryonic antigen...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Lynch HT,Thomas RJ,Gurgis HA,Lynch J

    更新日期:1975-03-01 00:00:00

  • Childhood bullying: implications for physicians.

    abstract::Childhood bullying has potentially serious implications for bullies and their targets. Bullying involves a pattern of repeated aggression, a deliberate intent to harm or disturb a victim despite the victim's apparent distress, and a real or perceived imbalance of power. Bullying can lead to serious academic, social, e...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Lyznicki JM,McCaffree MA,Robinowitz CB

    更新日期:2004-11-01 00:00:00

  • Treatment of Alzheimer disease.

    abstract::Alzheimer disease is the most common form of dementia, affecting nearly one-half [corrected] of Americans older than 85 years. It is characterized by progressive memory loss and cognitive decline. Amyloid plaque accumulation, neurofibrillary tau tangles, and depletion of acetylcholine are among the pathologic manifest...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Winslow BT,Onysko MK,Stob CM,Hazlewood KA

    更新日期:2011-06-15 00:00:00

  • Evaluating proteinuria in children.

    abstract::Proteinuria is a common laboratory finding in children. It can be identified as either a transient or a persistent finding and can represent a benign condition or a serious disease. A rapid but qualitative assessment of proteinuria can be made using dipstick or sulfosalicylic acid methods. More precise quantitation is...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Loghman-Adham M

    更新日期:1998-10-01 00:00:00

  • Infectious endocarditis: diagnosis and treatment.

    abstract::Infectious endocarditis results from bacterial or fungal infection of the endocardial surface of the heart and is associated with significant morbidity and mortality. Risk factors include the presence of a prosthetic heart valve, structural or congenital heart disease, intravenous drug use, and a recent history of inv...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Pierce D,Calkins BC,Thornton K

    更新日期:2012-05-15 00:00:00

  • Endoscopic papillotomy.

    abstract::Despite an 80 to 90 percent success rate in removing common bile duct stones, this technique has yet to receive universal acceptance in the United States. Originally developed for retained or newly formed common bile duct stones in patients with previous cholecystectomy, the procedure is now also used to remove common...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Kozarek RA,Sanowski RA

    更新日期:1981-03-01 00:00:00

  • Physician workforce: the special case of health centers and the National Health Service Corps.

    abstract::Federally funded health centers and the National Health Service Corps (NHSC) depend on family physicians (FPs) and general practitioners (GPs) to meet the needs of millions of medically underserved people. Policy makers and workforce planners should consider how changes in the production of FPs would affect these prog...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors:

    更新日期:2005-07-15 00:00:00

  • Pharmacologic prevention of osteoporotic fractures.

    abstract::Osteoporosis is characterized by low bone mineral density and a deterioration in the microarchitecture of bone that increases its susceptibility to fracture. The World Health Organization defines osteoporosis as a bone mineral density that is 2.5 standard deviations or more below the reference mean for healthy, young ...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Zizic TM

    更新日期:2004-10-01 00:00:00

  • Management of heart failure.

    abstract::Heart failure is associated with high rates of morbidity and mortality. Because heart failure is difficult to diagnose accurately on the basis of the history and physical examination alone, It is vital that clinical evaluation such as echocardiography be used to confirm the diagnosis. In addition, it is important to i...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Mair FS

    更新日期:1996-07-01 00:00:00

  • Fecal incontinence in children.

    abstract::Functional constipation is the cause of fecal incontinence in 95 percent of affected children, and anatomic or neurologic causes account for up to 5 percent of cases. The history and the physical examination (with emphasis on abdominal, rectal and neurologic examinations) are most helpful in identifying organic diseas...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Loening-Baucke V

    更新日期:1997-05-01 00:00:00

  • Prenatal genetic diagnosis.

    abstract::More than 100,000 children are born in the U.S. each year with major congenital defects or genetic disorders, with or without mental retardation. Advances in prenatal diagnosis have now made it possible to detect an increasing number of these disorders in utero. Carrier detection is advised prior to pregnancy, rather ...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Sandstrom MM,Milunsky A

    更新日期:1977-01-01 00:00:00

  • Pneumocystis carinii: a deadly opportunist.

    abstract::Pneumocystis carinii pneumonia is a life-threatening complication of diseases and therapies associated with immunosuppression. Approximately 80 percent of patients with acquired immunodeficiency syndrome will develop pneumocystis pneumonia. Diagnosis is important, because effective therapy is available. In most cases,...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Zackrison LH,Tsou E

    更新日期:1991-08-01 00:00:00

  • Identifying and managing preparatory grief and depression at the end of life.

    abstract::Grief and depression present similarly in patients who are dying. Conventional symptoms (e.g., frequent crying, weight loss, thoughts of death) used to assess for depression in these patients may be imprecise because these symptoms are also present in preparatory grief and as a part of the normal dying process. Prepar...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Periyakoil VS,Hallenbeck J

    更新日期:2002-03-01 00:00:00

  • Endometrial biopsy.

    abstract::Endometrial biopsy is an office procedure that serves as a helpful tool in diagnosing various uterine abnormalities. The technique is fairly easy to learn and may be performed without assistance. The biopsy is obtained through the use of an endometrial suction catheter that is inserted through the cervix into the uter...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Zuber TJ

    更新日期:2001-03-15 00:00:00

  • Differentiation and diagnosis of tremor.

    abstract::Tremor, an involuntary, rhythmic, oscillatory movement of a body part, is the most common movement disorder encountered in clinical practice. Rest tremors occur in a body part that is relaxed and completely supported against gravity. Action tremors occur with voluntary contraction of a muscle and can be further subdiv...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Crawford P,Zimmerman EE

    更新日期:2011-03-15 00:00:00

  • Hepatitis A.

    abstract::Hepatitis A is a common viral illness worldwide, although the incidence in the United States has diminished in recent years as a result of extended immunization practices. Hepatitis A virus is transmitted through fecal-oral contamination, and there are occasional outbreaks through food sources. Young children are usua...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Matheny SC,Kingery JE

    更新日期:2012-12-01 00:00:00

  • Gastroesophageal reflux in infants.

    abstract::Clinically significant gastroesophageal reflux occurs in one in 500 infants. Symptoms resolve in 60 to 80 percent of infants by 18 months of age. Thickened formula and position changes are often recommended. Medication and surgical intervention may be needed in refractory cases. ...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Dipalma J,Colon AR

    更新日期:1991-03-01 00:00:00

  • Anorectal disorders.

    abstract::Common anorectal disorders can produce one or more of the following symptoms: pain, protrusion, pruritus, bleeding or discharge. The cause may be cryptitis, anal fissure, hemorrhoids, anorectal abscess, fistula in ano, neoplasm, condylomata acuminata, pilonidal cyst or inflammatory bowel disease. Each disorder is sugg...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Arko FR

    更新日期:1980-10-01 00:00:00

  • The mattress sutures: vertical, horizontal, and corner stitch.

    abstract::The interrupted vertical and horizontal mattress suture techniques are two of the most commonly used skin closure methods. These mattress sutures promote wound edge eversion and less prominent scarring. Vertical and horizontal mattress sutures allow for skin edges to be closed under tension when wound edges have to be...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Zuber TJ

    更新日期:2002-12-15 00:00:00

  • New CPT codes: hospital, consultation, emergency and nursing facility services.

    abstract::New evaluation and management codes were created by the Current Procedural Terminology (CPT) Editorial Panel to ensure more accurate and consistent reporting of physician services. The new hospital inpatient codes describe three levels of service for both initial and subsequent care. Critical care services are reporte...

    journal_title:American family physician

    pub_type: 杂志文章

    doi:

    authors: Zuber TJ,Henley DE

    更新日期:1992-03-01 00:00:00

  • Ectopic pregnancy.

    abstract::Ectopic pregnancy occurs at a rate of 19.7 cases per 1,000 pregnancies in North America and is a leading cause of maternal mortality in the first trimester. Greater awareness of risk factors and improved technology (biochemical markers and ultrasonography) allow ectopic pregnancy to be identified before the developmen...

    journal_title:American family physician

    pub_type: 杂志文章,评审

    doi:

    authors: Tenore JL

    更新日期:2000-02-15 00:00:00