Abstract:
:Senile dementia of the Binswanger's type is a term used to describe a dementia syndrome characterized by onset in the sixth or seventh decade of life, subcortical neurologic deficits, psychiatric disorders and evidence of hypertension or systemic vascular disease. The status of senile dementia of the Binswanger's type as a distinct entity is a matter of some controversy. The array of neuroimaging abnormalities and clinical findings attributed to this condition overlap with a number of other neuropathologies. Leukoaraiosis, or attenuation of subcortical white matter, seen on computed tomographic scans or magnetic resonance imaging of the brain, is a hallmark of senile dementia of the Binswanger's type. The clinical findings associated with Binswanger's disease are varied but typically include a progressive dementia, depression and "subcortical" dysfunction such as gait abnormalities, rigidity and neurogenic bladder. Treatment is largely supportive and includes a discussion about advanced directives, social support and antidepressant therapy. Control of hypertension and aspirin prophylaxis may help prevent further progression of white matter disease.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Olsen CG,Clasen MEsubject
Has Abstractpub_date
1998-12-01 00:00:00pages
2068-74issue
9eissn
0002-838Xissn
1532-0650journal_volume
58pub_type
杂志文章,评审abstract::Appropriate preconception health care improves pregnancy outcomes. When started at least one month before conception, folic acid supplements can prevent neural tube defects. Targeted genetic screening and counseling should be offered on the basis of age, ethnic background, or family history. Before conception, women s...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2002-06-15 00:00:00
abstract::Nitrates are frequently found in vegetables and ground water. Nitrate levels in ground water have increased over the past two decades because of the heightened use of nitrogenous fertilizers. Following ingestion, nitrates are converted to nitrites by fecal organisms. Nitrites are absorbed and form methemoglobin, which...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1992-07-01 00:00:00
abstract::Although many physicians consider constipation a trivial problem, it is one of the most frequent and chronic digestive disorders in the United States, affecting 4.53 million people and causing considerable morbidity. More than $200 million are spent for over-the-counter laxatives and untold millions of dollars are spe...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1990-11-01 00:00:00
abstract::Mild elevations in levels of the liver enzymes alanine transaminase and aspartate transaminase are commonly discovered in asymptomatic patients in primary care. Evidence to guide the diagnostic workup is limited. If the history and physical examination do not suggest a cause, a stepwise evaluation should be initiated ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::The hallmark of agoraphobia is the spontaneous panic attack, a reaction of extreme fearfulness and impending doom with cardiorespiratory symptoms. The end result can be a patient who is housebound. The basic therapeutic principle is confrontation with the avoided object or activity. Controlled clinical experiments dem...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1981-01-01 00:00:00
abstract::Pressure sore are caused by multiple mechanisms. Preventive management requires relief of pressure, skin care, control of spasms, release of contractures and treatment of infection. Conservative treatment succeeds only when pressure on the ulcer site is relieved. Surgical treatment involves primary, secondary and tert...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1982-02-01 00:00:00
abstract::So many topical antifungal agents have been introduced that it has become very difficult to select the proper agent for a given infection. Nonspecific agents have been available for many years, and they are still effective in many situations. These agents include Whitfield's ointment, Castellani paint, gentian violet,...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::A large number of drugs are introduced every year, and new interactions between medications are increasingly reported. Consequently, it is no longer practical for physicians to rely on memory alone to avoid potential drug interactions. Multiple drug regimens carry the risk of adverse interactions. Precipitant drugs mo...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2000-03-15 00:00:00
abstract::Henoch-Schönlein purpura is an acute, systemic, immune complex-mediated, leukocytoclastic vasculitis. It is characterized by a triad of palpable purpura (without thrombocytopenia), abdominal pain, and arthritis. Most patients have an antecedent upper respiratory illness. More than 90 percent of Henoch-Schönlein purpur...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2009-10-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1984-01-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2000-09-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1995-04-01 00:00:00
abstract::Premature rupture of the membranes is associated with considerable neonatal and maternal morbidity when it leads to premature birth. In most cases, this condition occurs at term, does not require medical intervention and has a benign course. Although few effective preventive measures are available, the family physicia...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1993-08-01 00:00:00
abstract::Down syndrome is caused by triplicate material of chromosome 21. The syndrome has a variable physical expression, but congenital cardiac defects, transient myelodysplasia of the newborn and duodenal atresia are highly specific for this chromosomal disorder. Routine health maintenance is important because infants and c...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1999-01-15 00:00:00
abstract::Family physicians should be aware of the potential effects and complications of vasectomy so they can appropriately counsel patients seeking sterilization. Vasectomy produces anatomic, hormonal and immunologic changes and, although not substantiated by clinical studies, has been reputed to be associated with atheroscl...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1993-11-15 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-15 00:00:00
abstract::Family physicians can effectively help their patients stop smoking by using brief intervention and simple office organizational procedures. Intervention involves asking all patients about smoking, advising smokers to stop, assisting with self-help materials, establishing a date for quitting, possibly prescribing nicot...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1990-10-01 00:00:00
abstract::New beta lactams and the quinolone class of antibiotics represent major improvements in the therapy of moderate to severe infections. These newer antibiotics have an extended spectrum of antimicrobial activity, excellent pharmacokinetic properties and low toxicity. The beta lactams include carbapenems, represented by ...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1988-10-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2000-06-01 00:00:00
abstract::The best condoms are made of latex, are lubricated and coated with a spermicide, and have a reservoir tip. Condoms can protect against conception and sexually transmitted diseases, including acquired immunodeficiency syndrome. When condoms are used properly and in combination with vaginal spermicidal foam, the contrac...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1991-06-01 00:00:00
abstract::Vomiting, amnesia, a history of falls and other injuries, and depression and anxiety may all be clues to a drinking problem. Decreased work performance, absenteeism and difficulty in getting along with others may be present. Coming to grips with the problem is essential. Once the patient accepts the need for abstinenc...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1978-11-01 00:00:00
abstract::The differential diagnosis of eyelid erythema and edema is broad, ranging from benign, self-limiting dermatoses to malignant tumors and vision-threatening infections. A definitive diagnosis usually can be made on physical examination of the eyelid and a careful evaluation of symptoms and exposures. The finding of a sw...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2007-12-15 00:00:00
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journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1985-10-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2006-10-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2004-06-15 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2006-03-15 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1992-08-01 00:00:00
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journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract::Down syndrome (trisomy 21) is the most commonly recognized genetic cause of mental retardation. The risk of trisomy 21 is directly related to maternal age. All forms of prenatal testing for Down syndrome must be voluntary. A nondirective approach should be used when presenting patients with options for prenatal screen...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2000-08-15 00:00:00
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journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2003-09-01 00:00:00