Abstract:
:Nearly 40 percent of Americans complain about insomnia. Such complaints are even more common among the elderly, possibly because sleep efficiency decreases with age. As a result, the use of hypnotics in this age group is high--sometimes too high. Hypnotics can be addictive, and many have a low therapeutic index. The benzodiazepine agents are safest for use in the elderly. Many elderly patients exhibit a marked increase in sensitivity to these hypnotics.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Lamy PPsubject
Has Abstractpub_date
1984-08-01 00:00:00pages
187-91issue
2eissn
0002-838Xissn
1532-0650journal_volume
30pub_type
杂志文章abstract::Early prophylaxis after exposure to human immunodeficiency virus (HIV) can reduce the risk of HIV infection 10-fold and should be recommended or offered after all parenteral exposures. The current recommendations from the Centers for Disease Control and Prevention call for the use of two nucleoside antiretroviral drug...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-01 00:00:00
abstract::So many topical antifungal agents have been introduced that it has become very difficult to select the proper agent for a given infection. Nonspecific agents have been available for many years, and they are still effective in many situations. These agents include Whitfield's ointment, Castellani paint, gentian violet,...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Healing by primary intention is a threefold process, consisting of an initial phase in which red and white blood cells bind the wound; epithelialization and fibroplasia, and a maturation phase involving collagen synthesis. The appearance of the wound reflects its maturation. Skillful wound management is based on biolo...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::Most of the nearly 4 million births in the United States annually are normal spontaneous vaginal deliveries. In the first stage of labor, normal birth outcomes can be improved by encouraging the patient to walk and stay in upright positions, waiting until at least 6 cm dilation to diagnose active stage arrest, providi...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2015-08-01 00:00:00
abstract::Knee effusions may be the result of trauma, overuse or systemic disease. An understanding of knee pathoanatomy is an invaluable part of making the correct diagnosis and formulating a treatment plan. Taking a thorough medical history is the key component of the evaluation. The most common traumatic causes of knee effus...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2000-04-15 00:00:00
abstract::Primary carcinoma of the fallopian tube is a rare disease and has traditionally been managed in the same manner as epithelial ovarian cancer. However, unlike ovarian cancer, fallopian tube cancer is not routinely suspected and treatment may be delayed. The clinical presentations of seven cases of fallopian tube cancer...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::Portal hypertension is a frequent consequence of liver disease, especially alcoholic cirrhosis. Unabated elevations in portal pressure may presage an esophageal variceal hemorrhage. Propranolol or isosorbide therapy is effective in the prophylaxis of variceal bleeding. In patients with acute variceal hemorrhage, endos...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract::Anemia in children is commonly encountered by the family physician. Multiple causes exist, but with a thorough history, a physical examination and limited laboratory evaluation a specific diagnosis can usually be established. The use of the mean corpuscular volume to classify the anemia as microcytic, normocytic or ma...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2001-10-15 00:00:00
abstract::The classic modes of heat loss affecting the newborn are conduction, convection, radiation and evaporation. The disproportionate ratio of surface area to body weight (SA/BW) of the premature infant is the basis of inefficient heat conservation, combined with a blunted metabolic response. Hypothermia leads to hypoxemia...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1977-11-01 00:00:00
abstract::Historically, osteopathic physicians have made an important contribution to the primary care workforce. More than one half of osteopathic physicians are primary care physicians, and most of these are family physicians. However, the proportion of osteopathic students choosing family medicine, like that of their allopat...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2005-08-15 00:00:00
abstract::The family physician often provides the first and only medical intervention for fingertip injuries. Proper diagnosis and management of fingertip injuries are vital to maintaining proper function of the hand and preventing permanent disability. A subungual hematoma is a painful condition that involves bleeding beneath ...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-15 00:00:00
abstract::Myocardial infarction and congestive heart failure are associated with high morbidity and mortality rates. The results of recent clinical trials support a beneficial role for angiotensin-converting enzyme (ACE) inhibitors in attenuating mortality from myocardial infarction and left ventricular dysfunction. Large-scale...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract::Thyroiditis is a spectrum of diseases that includes acute, subacute and chronic thyroiditis, all of which demonstrate the histologic findings of inflammation, fibrosis or lymphocytic infiltration. Acute thyroiditis is an infectious disease characterized by the abrupt onset of anterior neck pain and swelling. Subacute ...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-15 00:00:00
abstract::Asymptomatic bacteriuria, defined as the presence of bacteria in the urine in the absence of urinary symptoms, is a common clinical finding that often warrants a decision about whether to initiate antimicrobial therapy. There are few indications to treat asymptomatic bacteriuria, and inappropriate treatment contribute...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2020-07-15 00:00:00
abstract::Cytochrome P450 enzymes are essential for the metabolism of many medications. Although this class has more than 50 enzymes, six of them metabolize 90 percent of drugs, with the two most significant enzymes being CYP3A4 and CYP2D6. Genetic variability (polymorphism) in these enzymes may influence a patient's response t...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2007-08-01 00:00:00
abstract::Traveler's diarrhea is the most common health problem in persons who visit developing countries. Dietary precautions are the mainstay of prevention. Since bacteria are responsible for 50 to 80 percent of cases of traveler's diarrhea, antibiotics are the drugs of choice for empiric therapy. Because bacteria are becomin...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1993-10-01 00:00:00
abstract::More than 100,000 children are born in the U.S. each year with major congenital defects or genetic disorders, with or without mental retardation. Advances in prenatal diagnosis have now made it possible to detect an increasing number of these disorders in utero. Carrier detection is advised prior to pregnancy, rather ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1977-01-01 00:00:00
abstract::Mild elevations in levels of the liver enzymes alanine transaminase and aspartate transaminase are commonly discovered in asymptomatic patients in primary care. Evidence to guide the diagnostic workup is limited. If the history and physical examination do not suggest a cause, a stepwise evaluation should be initiated ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::More than 30% of U.S. adults report having experienced low back pain within the preceding three months. Although most low back pain is nonspecific and self-limiting, a subset of patients develop chronic low back pain, defined as persistent symptoms for longer than three months. Low back pain is categorized as nonspeci...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2015-05-15 00:00:00
abstract::Aspirin should not be used to treat acute febrile viral illness in children. (Strength of Recommendation [SOR]: C, based on case-control studies). Although no causal link has been proven, data from case-control and historic cohort studies demonstrate an association between aspirin use and Reye syndrome. The risk of Re...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2009-12-15 00:00:00
abstract::Many normal children have heart murmurs, but most children do not have heart disease. An appropriate history and a properly conducted physical examination can identify children at increased risk for significant heart disease. Pathologic causes of systolic murmurs include atrial and ventricular septal defects, pulmonar...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1999-08-01 00:00:00
abstract::Middle ear fluid is a common problem in children. Eustachian tube dysfunction has been considered the key to the pathogenesis of this disorder, but new studies show that other factors may be operative. Inflammation appears to play a significant role in high-viscosity effusion, and these effusions may be related to acu...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1978-04-01 00:00:00
abstract::The incidence of malignant melanoma has increased in recent years more than that of any other cancer in the United States. About one in 70 people will develop melanoma during their lifetime. Family physicians should be aware that a patient with a changing mole, an atypical mole or multiple nevi is at considerable risk...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
abstract::Tremor, an involuntary, rhythmic, oscillatory movement of a body part, is the most common movement disorder encountered in clinical practice. Rest tremors occur in a body part that is relaxed and completely supported against gravity. Action tremors occur with voluntary contraction of a muscle and can be further subdiv...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2011-03-15 00:00:00
abstract::After the safety and the tolerable dosage range of a new drug have been determined, it must be evaluated for efficacy and safety in patients having the condition for which the new drug is intended. The nature of certain drugs or diseases of of the patient population desired may suggest a family physician as the best d...
journal_title:American family physician
pub_type: 临床试验,杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::Pneumocystis carinii pneumonia is a life-threatening complication of diseases and therapies associated with immunosuppression. Approximately 80 percent of patients with acquired immunodeficiency syndrome will develop pneumocystis pneumonia. Diagnosis is important, because effective therapy is available. In most cases,...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1991-08-01 00:00:00
abstract::Dorsal penile nerve block with lidocaine is safe and effective for reducing the pain associated with newborn circumcision. Administering the anesthesia adds little time or expense to the overall routine. Complications are minor, limited to local bleeding and hematoma formation. Family physicians performing circumcisio...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1991-04-01 00:00:00
abstract::Cystic masses of the neck may represent thyroid, parathyroid, thyroglossal duct or branchial cleft cysts. Analysis of the cyst fluid may establish the etiology. Elevated levels of parathyroid hormone can be found in parathyroid cysts without concomitant hyperparathyroidism. A high concentration of cholesterol without ...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1989-07-01 00:00:00
abstract::Tricyclic antidepressants have anticholinergic, adrenolytic and quinidine-like activity. These actions result in a variety of cardiac and blood pressure effects. Tricyclic antidepressants can reverse the antihypertensive effect of guanethidine and clonidine. Orthostatic hypotension may be increased with diuretics and ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::Atypical moles can be distinguished visually by clinical features of size greater than 6 mm in diameter, color variegation, indistinct borders, and textured surface. All patients who have atypical moles should be counselled about sun avoidance, screening of family members, and regular skin checks at least once per yea...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2008-09-15 00:00:00