The neuromuscular junction. Part II: myasthenia gravis.

Abstract:

:Myasthenia gravis is characterized by variable ocular and skeletal muscle weakness. Peak incidence is in young women and older men. Thymomas are present in 30 percent of myasthenic patients over age 40. Binding of acetylcholine receptors by IgG antibodies may be the mechanism of the neuromuscular disorder. Repetitive nerve stimulation (Jolly test), provocative tests with quinine or curare and the edrophonium test (cholinesterase inhibition) are the diagnostic maneuvers employed.

journal_name

Am Fam Physician

authors

Brumback RA

subject

Has Abstract

pub_date

1981-02-01 00:00:00

pages

126-33

issue

2

eissn

0002-838X

issn

1532-0650

journal_volume

23

pub_type

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