Abstract:
:Myasthenia gravis is characterized by variable ocular and skeletal muscle weakness. Peak incidence is in young women and older men. Thymomas are present in 30 percent of myasthenic patients over age 40. Binding of acetylcholine receptors by IgG antibodies may be the mechanism of the neuromuscular disorder. Repetitive nerve stimulation (Jolly test), provocative tests with quinine or curare and the edrophonium test (cholinesterase inhibition) are the diagnostic maneuvers employed.
journal_name
Am Fam Physicianjournal_title
American family physicianauthors
Brumback RAsubject
Has Abstractpub_date
1981-02-01 00:00:00pages
126-33issue
2eissn
0002-838Xissn
1532-0650journal_volume
23pub_type
杂志文章abstract::Early prophylaxis after exposure to human immunodeficiency virus (HIV) can reduce the risk of HIV infection 10-fold and should be recommended or offered after all parenteral exposures. The current recommendations from the Centers for Disease Control and Prevention call for the use of two nucleoside antiretroviral drug...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1997-02-01 00:00:00
abstract::Pneumocystis carinii pneumonia is a life-threatening complication of diseases and therapies associated with immunosuppression. Approximately 80 percent of patients with acquired immunodeficiency syndrome will develop pneumocystis pneumonia. Diagnosis is important, because effective therapy is available. In most cases,...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1991-08-01 00:00:00
abstract::Subungual hemorrhage, onychauxis, onychogryphosis, mycotic infections, onychia and paronychia are common toenail disorders in the elderly. The many contributing factors include impaired vision, changes in gait, past foot conditions and neurovascular disease. Hyperkeratotic disorders are secondary to external or intern...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1989-02-01 00:00:00
abstract::Irritable bowel syndrome is the most common functional disorder of the gastrointestinal tract and is frequently treated by family physicians. Despite patients' worries about the symptoms of irritable bowel syndrome, it is a benign condition. The diagnosis should be made using standard criteria after red flags that may...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2002-11-15 00:00:00
abstract::The physician is increasingly asked to play a role in relocating elderly patients to special housing. The goal is to find the housing that is best suited to the patient's needs. Important factors to be considered are building design, sponsorship, financing and nonshelter services. Proper housing, with appropriate supp...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1985-06-01 00:00:00
abstract::Prompt diagnosis of problems in the first trimester of pregnancy is facilitated by ultrasound scanning and quantitative serum human chorionic gonadotropin and progesterone testing. When used appropriately, these tests can determine whether a patient has a normal early pregnancy, a miscarriage, a missed abortion, an ec...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1991-11-01 00:00:00
abstract::The family physician often provides the first and only medical intervention for fingertip injuries. Proper diagnosis and management of fingertip injuries are vital to maintaining proper function of the hand and preventing permanent disability. A subungual hematoma is a painful condition that involves bleeding beneath ...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2001-05-15 00:00:00
abstract::Disposable soft contact lenses are an alternative to conventional extended-wear lenses and provide an acceptable margin of safety and convenience for the wearer. The lenses are worn for one to two weeks and then discarded. Buildup of tear film deposits is minimized, and the need for cleaning and disinfecting solutions...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1991-05-01 00:00:00
abstract::This is a minimally invasive imaging technique designed to evaluate patients for suspected coronary artery disease. It is usually performed in conjunction with stress ECG testing. It can accurately determine the presence and extent of coronary artery disease and help determine whether cardiac catheterization is necess...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract::Mild elevations in levels of the liver enzymes alanine transaminase and aspartate transaminase are commonly discovered in asymptomatic patients in primary care. Evidence to guide the diagnostic workup is limited. If the history and physical examination do not suggest a cause, a stepwise evaluation should be initiated ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2011-11-01 00:00:00
abstract::The specific type of epilepsy must be identified. The history and the EEG provide the evidence. Drug selection is then based on the classification of the patient's epilepsy. Major drugs used in the management of epilepsy are phenytoin, phenobarbital, primidone, carbamazepine, ethosuximide and valproic acid. The physic...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1978-10-01 00:00:00
abstract::This is a tenosynovitis of the abductor pollicis longus and extensor pollicis brevis tendons contained within the osseofibrous tunnel of the distal radius. Multiple tendons for the abductor pollicis longus and a separate, severely narrowed sheath for the extensor pollicis brevis make nonsurgical treatment difficult at...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1979-07-01 00:00:00
abstract::Careful examination of a fresh, properly collected urine specimen can indicate the presence of urinary tract disease or uncover unsuspected local or systemic pathology. Urinalysis also can lead to a more complete understanding of a systemic disorder or can assure both the patient and the physician that urinary tract d...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::In many cases, the family physician will set the tone for rehabilitation of the stroke patient. It is imperative that the physician understand the recovery process, as well as the nature, benefits and limitations of rehabilitation. Since there are no precise predictors of individual outcome, no patient should be exclu...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1982-11-01 00:00:00
abstract::Colorectal cancer is the third most common cancer in men and women. The incidence and mortality rate of the disease have been declining over the past two decades because of early detection and treatment. Screening in persons at average risk should begin at 50 years of age; the U.S. Preventive Services Task Force recom...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2015-01-15 00:00:00
abstract::Schirmer's test is a simple, semiquantitative test of tear production. It is based on the physical tendency of a fluid to travel along a strip of porous material by capillary action due to surface tension. Sterile strips, standardized and prepackaged, are available from local scientific supply houses. The low cost and...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1981-11-01 00:00:00
abstract::Breast milk is universally recommended as the preferred source of infant nutrition, in part because of its superior nutrient and immunologic properties. Successful breast feeding requires nursing on demand, prevention of sore nipples and convenient access to medical advice. For mothers relying on bottle feeding, cow's...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1996-07-01 00:00:00
abstract::Common anorectal conditions include hemorrhoids, perianal pruritus, anal fissures, functional rectal pain, perianal abscess, condyloma, rectal prolapse, and fecal incontinence. Although these are benign conditions, symptoms can be similar to those of cancer, so malignancy should be considered in the differential diagn...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2020-01-01 00:00:00
abstract::Self-care is becoming increasingly popular among health care consumers. The availability of over-the-counter medications makes it possible for consumers to treat numerous ailments without the supervision of a health care professional. Many of the medications now available without a prescription were previously classif...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1998-05-01 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is the most common form of liver disease in the United States, affecting up to 30% of adults. There are two forms of NAFLD: nonalcoholic fatty liver (NAFL), defined as 5% or greater hepatic steatosis without hepatocellular injury or fibrosis, and nonalcoholic steatohepatitis (N...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2020-11-15 00:00:00
abstract::The incidence of malignant melanoma has increased in recent years more than that of any other cancer in the United States. About one in 70 people will develop melanoma during their lifetime. Family physicians should be aware that a patient with a changing mole, an atypical mole or multiple nevi is at considerable risk...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:2001-04-01 00:00:00
abstract::Portal hypertension is a frequent consequence of liver disease, especially alcoholic cirrhosis. Unabated elevations in portal pressure may presage an esophageal variceal hemorrhage. Propranolol or isosorbide therapy is effective in the prophylaxis of variceal bleeding. In patients with acute variceal hemorrhage, endos...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1997-04-01 00:00:00
abstract::Low-molecular-weight heparin is a relatively recent addition to the list of therapies for prophylaxis and treatment of deep venous thrombosis (DVT). As a prophylactic, low-molecular-weight heparin is as effective as standard heparin or warfarin and does not require monitoring of the activated partial thromboplastin ti...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1999-03-15 00:00:00
abstract::Nitrous oxide analgesia is a safe alternative to parenteral narcotics for outpatient surgical procedures. This type of analgesia is effective, well tolerated by most age groups, easily administered, rapidly reversible and associated with a low incidence of serious side effects. Hypoxia can be prevented by using fail-s...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00
abstract::Postpartum hemorrhage, the loss of more than 500 mL of blood after delivery, occurs in up to 18 percent of births and is the most common maternal morbidity in developed countries. Although risk factors and preventive strategies are dearly documented, not all cases are expected or avoidable. Uterine atony is responsibl...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2007-03-15 00:00:00
abstract::Although laparoscopy has been available since the turn of the century, the technique did not become widely accepted for gastrointestinal surgery until it was used in cholecystectomy. Since then, various gastrointestinal operations have been performed using laparoscopic guidance. Laparoscopic operations must conform to...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::Burns are the second most common cause of death in childhood. More than half of pediatric burns are partial-thickness scald burns; the majority occur in the kitchen. Generally, minor burns may be treated on an outpatient basis, while moderate burns are treated in a community hospital. Children with major burns should ...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1987-10-01 00:00:00
abstract::So many topical antifungal agents have been introduced that it has become very difficult to select the proper agent for a given infection. Nonspecific agents have been available for many years, and they are still effective in many situations. These agents include Whitfield's ointment, Castellani paint, gentian violet,...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Patients with symptomatic lumbar disk disease may present with back pain, referred leg pain, radicular leg pain, sensory changes and leg weakness. Because neurologic deficits are commonly localized to the L5 or S1 nerve roots, evaluation of patients with such symptoms should focus on these dermatomes and muscle groups...
journal_title:American family physician
pub_type: 杂志文章,评审
doi:
更新日期:1993-04-01 00:00:00
abstract::Gas, bloating, and belching are associated with a variety of conditions but are most commonly caused by functional gastrointestinal disorders. These disorders are characterized by disordered motility and visceral hypersensitivity that are often worsened by psychological distress. An organized approach to the evaluatio...
journal_title:American family physician
pub_type: 杂志文章
doi:
更新日期:2019-03-01 00:00:00