Alpha-tubulins of Tritrichomonas mobilensis are encoded by multiple genes and are not posttranslationally tyrosinated.

Abstract:

:Reverse-transcriptase polymerase chain reaction cloning of the 3'-ends of the alpha-tubulin cDNAs of Tritrichomonas mobilensis in combination with Southern-blot analysis identified seven to eight distinct alpha-tubulin genes. All seven lack a carboxy-terminal tyrosine and the corresponding sequence compatible with posttranslational tyrosination. This indicates that whereas tyrosination of alpha-tubulin has been found in most species, including humans and trypanosomes, it is absent in trichomonads.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Schneider A,Plessmann U,Felleisen R,Weber K

doi

10.1007/s004360050542

subject

Has Abstract

pub_date

1999-03-01 00:00:00

pages

246-8

issue

3

eissn

0932-0113

issn

1432-1955

journal_volume

85

pub_type

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