Image processing in forensic pathology.

abstract：:To date, CRP remains the single standard biochemical marker for predicting the severity of AP. Because the combination of clinico-physiological scores and CRP provides good information at 48 hours, research has focused on the predictive ability of various markers when applied in the initial 24 hours after admission to...

journal_title：Clinics in laboratory medicine

authors： Papachristou GI,Whitcomb DC

更新日期：2005-03-01 00:00:00

abstract：:Yellow fever (YF) is a viral disease, endemic to tropical regions of Africa and the Americas, which principally affects humans and nonhuman primates and is transmitted via the bite of infected mosquitoes. Yellow fever virus (YFV) can cause devastating epidemics of potentially fatal, hemorrhagic disease. Despite mass v...

journal_title：Clinics in laboratory medicine

authors： Gardner CL,Ryman KD

更新日期：2010-03-01 00:00:00

abstract：:To meet the challenges of diagnosis and management of infectious diseases, clinical pathology residents must receive comprehensive training in microbiology, learn to think critically, develop problem-solving skills, and take active roles as laboratory consultants. Residents well trained in clinical microbiology become...

journal_title：Clinics in laboratory medicine

authors： Haller BL

更新日期：2007-06-01 00:00:00

abstract：:Cytomorphological examination of aspirate smears remains the basic method to diagnose hematologic disorders and to evaluate treatment-related changes. Last-generation hematological analyzers can count, besides cells normally circulating in peripheral blood, some types of immature and abnormal cells, such as erythrobla...

journal_title：Clinics in laboratory medicine

authors： d'Onofrio G,Zini G

更新日期：2015-03-01 00:00:00

abstract：:Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions. Preliminary survey results show the need for point-of-care testing (POCT) devices using test clusters that specifically detect pathogens...

journal_title：Clinics in laboratory medicine

authors： Kost GJ,Hale KN,Brock TK,Louie RF,Gentile NL,Kitano TK,Tran NK

更新日期：2009-09-01 00:00:00

abstract：:The optimal care of septic patients depends on the successful recovery of clinically relevant microorganisms from blood cultures and the timely reporting of organism identification and antimicrobial susceptibility testing (AST) results. Many preanalytic factors play a critical role in culturing microorganisms, and adv...

journal_title：Clinics in laboratory medicine

authors： Gonzalez MD,Chao T,Pettengill MA

更新日期：2020-12-01 00:00:00

abstract：:Clinical decision support (CDS) can greatly enhance patient blood management through optimizing ordering and providing patient-specific information. At present, modeling and prediction have small roles in inventory management; they will likely have increasing applications to help guide donor center collections based o...

journal_title：Clinics in laboratory medicine

authors： Shah NK

更新日期：2019-06-01 00:00:00

abstract：:Normal thermogenesis requires a complex interaction between systems that generate and dissipate heat. Serving as director of thermogenesis, the hypothalamus activates the sympathetic nervous system along with the thyroid and adrenal glands to respond to changes in body temperature. Working in concert, these systems re...

journal_title：Clinics in laboratory medicine

authors： Rusyniak DE,Sprague JE

更新日期：2006-03-01 00:00:00

abstract：:The development and adaptation of synthetic substrates has introduced new concepts and methodologies to the coagulation laboratory. Synthetic substrates offer potentially improved standardization over conventional testing, providing a rapid, sensitive, and specific way to measure enzymes directly. ...

journal_title：Clinics in laboratory medicine

authors： Musgrave KA,Triplett DA

更新日期：1984-06-01 00:00:00

abstract：:FNA cytology has been shown to be highly accurate in diagnosing malignant tumors. In gynecology, an overall accuracy of 94.5% in the differentiation between benign and malignant tumors has been reported. Despite many controversial views regarding its safety, aspiration cytology has been accepted as an innocuous proced...

journal_title：Clinics in laboratory medicine

authors： Ganjei P

更新日期：1995-09-01 00:00:00

abstract：:This article attempts to define and identify sources of variation in laboratory analysis that occur predominantly "away" from the analytic bench. Problems in the derivation and application of reference ranges are reviewed and sources of non-analytic error are "located" within the entire testing cycle. Reference source...

journal_title：Clinics in laboratory medicine

authors： Bachner P

更新日期：1986-12-01 00:00:00

abstract：:Noninvasive genomic assessments of the fetus while in utero have been made possible by the analysis of cell-free fetal DNA fragments from the serum of pregnant women, as part of a noninvasive prenatal testing screening strategy. Between 7% and 10% of total cell-free DNA in the maternal blood comes from placental troph...

journal_title：Clinics in laboratory medicine

authors： Long AA,Abuhamad AZ,Warsof SL

更新日期：2016-06-01 00:00:00

abstract：:The last decade has witnessed the transformation of first-trimester Down syndrome screening from an aspiration to a clinical reality. First-trimester screening now equals or exceeds the diagnostic accuracy of conventional midtrimester screen while realizing an important desire of pregnant women for early diagnosis. Be...

journal_title：Clinics in laboratory medicine

authors： Bahado-Singh RO,Argoti P

更新日期：2010-09-01 00:00:00

abstract：:The cause of colorectal cancer (CRC) is multifactorial, with genetic, molecular, inflammatory, and environmental risk factors. Recently, the gut microbiota has been recognized as a new environmental contributor to CRC in both animal models and human studies. An additional interplay of the gut microbiome with inflammat...

journal_title：Clinics in laboratory medicine

authors： Cho M,Carter J,Harari S,Pei Z

更新日期：2014-12-01 00:00:00

abstract：:Diseases due to nontuberculous mycobacteria are increasing in frequency, especially in patients with compromised immunity. A number of "new" mycobacterial species have been described in the last decade, largely as the result of the use of new tools to identify previously unrecognized mycobacteria found in the environm...

journal_title：Clinics in laboratory medicine

authors： Herdman AV,Steele JC Jr

更新日期：2004-09-01 00:00:00

abstract：:A formal therapeutic drug monitoring consultation service (TDMCS) will enhance the clinical benefits of drug level determinations. It can result in decreased length of stay and improved risk management posture. The successful implementation of a TDMCS requires the coordinated efforts of a multidisciplinary team that m...

journal_title：Clinics in laboratory medicine

authors： Wilkinson DS

更新日期：1987-06-01 00:00:00

abstract：:With the US Food and Drug Administration's recent label change of warfarin to include genetic testing for warfarin sensitivity, manufacturers are developing assays, and laboratories are offering testing. This article describes the genetic variants for which testing is available. Current technologies and assays are com...

journal_title：Clinics in laboratory medicine

authors： Lyon E,McMillin G,Melis R

更新日期：2008-12-01 00:00:00

abstract：:The category of provider-performed microscopy was defined in the Federal Register to provide a unique regulatory approach for bright-field and phase-contrast microscopy performed by a physician, dentist, or midlevel practitioner examining labile specimens. A CLIA certificate for this category of testing is available, ...

journal_title：Clinics in laboratory medicine

authors： Kiechle FL,Gauss I

更新日期：2001-06-01 00:00:00

abstract：:Diabetes mellitus affects almost 16 million Americans. It has become a major public health problem and the number one cause of adult blindness, end-stage renal disease, and nontraumatic amputations in the United States. It also markedly increases the risk for cardiovascular, cerebrovascular, and peripheral artery dise...

journal_title：Clinics in laboratory medicine

authors： Kazi AA,Blonde L

更新日期：2001-03-01 00:00:00

abstract：:Respiratory viruses continue to be major causes of morbidity and mortality. Currently available chemotherapy is limited to oral amantadine for uncomplicated influenza A and aerosolized ribavirin for respiratory syncytial virus (RSV) infections. Amantadine is also efficacious for chemoprophylaxis of influenza A virus i...

journal_title：Clinics in laboratory medicine

authors： Sperber SJ,Hayden FG

更新日期：1987-12-01 00:00:00

abstract：:Lyme disease in North America is caused by infection with the spirochetal bacterium Borrelia burgdorferi and transmitted by Ixodes scapularis and Ixodes pacificus ticks. These ticks also have the potential to transmit a rapidly expanding list of other pathogenic bacteria, viruses, and parasites, including Anaplasma ph...

journal_title：Clinics in laboratory medicine

authors： Caulfield AJ,Pritt BS

更新日期：2015-12-01 00:00:00

abstract：:With a focus on low-cost and low-power consumption, a miniature laser-induced fluorescence (LIF) detection system was assembled using a 635 nm red diode laser as the excitation source and a photodiode element coupled with an operational amplifier for signal collection. The primary elements of the miniature system, nam...

journal_title：Clinics in laboratory medicine

authors： Shrinivasan S,Norris PM,Landers JP,Ferrance JP

更新日期：2007-03-01 00:00:00

abstract：:Screening tests may help or harm the healthy subject and, therefore, must be selected and used carefully. Criteria for selection include characteristics of the disease(s), of the potential screening tests, and of the population(s) to be screened. An understanding of methods used to evaluate tests will allow the invest...

journal_title：Clinics in laboratory medicine

authors： Mulley AG

更新日期：1986-06-01 00:00:00

abstract：:The interpretation of the total serum testosterone concentration is problematic because it is related directly to the serum SHBG concentration.Frequently, an estimate of the serum free testosterone concentration is obtained to better assess the clinical status of the patient. We reviewed five methods for the determina...

journal_title：Clinics in laboratory medicine

authors： Elin RJ,Winters SJ

更新日期：2004-03-01 00:00:00

abstract：:There are multiple levels of transcriptional regulation that a cell can bring to bear on either native cellular genes or integrated proviral genes. One such level of regulation is inducible sequence-specific transcriptional factors, such as NF-kappa B, which have been extensively investigated with respect to the HIV-1...

journal_title：Clinics in laboratory medicine

authors： Laughlin MA,Pomerantz RJ

更新日期：1994-06-01 00:00:00

abstract：:Granulocytic sarcoma is a variant presentation of acute myeloblastic leukemia, occurring in extramedullary locations. It is uncommon, but it may occur at any site and at any age, which necessitates its inclusion in the differential diagnosis of all undifferentiated tumors. Histology, touch-imprint cytology, cytochemis...

journal_title：Clinics in laboratory medicine

authors： Hutchison RE,Kurec AS,Davey FR

更新日期：1990-12-01 00:00:00

abstract：:Antiretroviral failure caused by the development of drug resistance in HIV-1 is an increasingly common clinical problem. Two types of resistance assays are available to clinicians. Genotypic assays determine the presence of mutations associated with drug resistance. The interpretation of mutations is often complicated...

journal_title：Clinics in laboratory medicine

authors： Hanna GJ

更新日期：2002-09-01 00:00:00

abstract：:Disease prevention requires sociopolitical change, which in turn requires the participation of those for whom the change is intended, including demographic groups at high risk for disease, appropriate governmental authorities, and essential health care personnel. Multiparous women of lowest socioeconomic status, the d...

journal_title：Clinics in laboratory medicine

authors： Suba EJ

更新日期：2004-12-01 00:00:00

abstract：:At the present time, the use of molecular techniques for diagnosing the neurologic porphyrias is limited mainly to those laboratories doing research in the area. Because any of four genes may be involved, it is important to confirm the diagnosis in the index case before undertaking molecular investigation. With advanc...

journal_title：Clinics in laboratory medicine

authors： Schreiber WE

更新日期：1997-03-01 00:00:00

abstract：:Seven different mycoplasmas have been isolated from the human genitourinary tract. The diseases they cause or with which they have been associated are described. Diagnosis of infection by cultural and noncultural (antigen detection, DNA probes) methods is discussed in detail. The more useful serologic procedures are i...

journal_title：Clinics in laboratory medicine

authors： Taylor-Robinson D

更新日期：1989-09-01 00:00:00