Abstract:
:With a focus on low-cost and low-power consumption, a miniature laser-induced fluorescence (LIF) detection system was assembled using a 635 nm red diode laser as the excitation source and a photodiode element coupled with an operational amplifier for signal collection. The primary elements of the miniature system, namely the laser and the detection system, cost a combined $70 and required only 270 mW of power for operation. When compared to conventional systems assembled using an argon-ion laser source and a photomultiplier tube, this represents a 98% decrease in the cost, and greater than 5000-fold decrease in power consumption. Quantitation of DNA on microdevices using the miniature LIF detection system was also performed with an error of less than 15%. This detection system is a step in the direction of commercializing microfluidic instrumentation by reducing the cost and power required for operation.
journal_name
Clin Lab Medjournal_title
Clinics in laboratory medicineauthors
Shrinivasan S,Norris PM,Landers JP,Ferrance JPdoi
10.1016/j.cll.2006.12.010subject
Has Abstractpub_date
2007-03-01 00:00:00pages
173-81issue
1eissn
0272-2712issn
1557-9832pii
S0272-2712(06)00114-4journal_volume
27pub_type
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journal_title:Clinics in laboratory medicine
pub_type: 历史文章,杂志文章,评审
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journal_title:Clinics in laboratory medicine
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journal_title:Clinics in laboratory medicine
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journal_title:Clinics in laboratory medicine
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