Abstract：
:Granulocytic sarcoma is a variant presentation of acute myeloblastic leukemia, occurring in extramedullary locations. It is uncommon, but it may occur at any site and at any age, which necessitates its inclusion in the differential diagnosis of all undifferentiated tumors. Histology, touch-imprint cytology, cytochemistry, immunocytochemistry, electron microscopy, and molecular studies all contribute to the diagnosis.
journal_name
Clin Lab Medjournal_title
Clinics in laboratory medicineauthors
Hutchison RE,Kurec AS,Davey FRsubject
Has Abstractpub_date
1990-12-01 00:00:00pages
889-901issue
4eissn
0272-2712issn
1557-9832journal_volume
10pub_type
杂志文章,评审abstract：:Chromosome analysis is the genetic technique useful in evaluating endocrine disease. Indications for cytogenetic studies include suspected sex chromosomal aneuploidies as well as repeated fetal wastage. In patients with ambiguous genitalia, cytogenetic studies are mandatory, not only to provide information for assigni...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1984-12-01 00:00:00
abstract：:During the past 20 years, laboratory systems have evolved to a high degree of complexity. In some cases, continuing addition of new features has adversely affected functionality. There is increasing recognition that the number of features listed on a request for proposal does not necessarily provide an accurate guide ...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1991-03-01 00:00:00
abstract：:The primary product of the laboratory is information. Greater attention should be devoted to how laboratory reports are presented to ensure that information is being conveyed effectively to the clinician. Different reporting techniques, including test-by-test, interim, cumulative, and completed accession reports, are ...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1991-03-01 00:00:00
abstract：:In marked contrast to their historical classification as relatively harmless, common cold-causing, respiratory pathogens, human coronaviruses (HCoVs) are associated with more severe clinical complications, as emphasized by the discovery of severe acute respiratory syndrome-associated CoV (SARS-CoV) in 2003. Still, the...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2009.07.007
更新日期：2009-12-01 00:00:00
abstract：:The last decade has witnessed the transformation of first-trimester Down syndrome screening from an aspiration to a clinical reality. First-trimester screening now equals or exceeds the diagnostic accuracy of conventional midtrimester screen while realizing an important desire of pregnant women for early diagnosis. Be...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2010.05.001
更新日期：2010-09-01 00:00:00
abstract：:Shiga toxin-producing Escherichia coli (STEC) are important enteric pathogens worldwide, causing diarrhea with or without blood visibly present and hemolytic uremic syndrome. STEC are unique among diarrheogenic E coli in producing Shiga toxin type 1 and type 2, the virulence factors responsible for bloody diarrhea and...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2009.11.001
更新日期：2010-03-01 00:00:00
abstract：:Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions. Preliminary survey results show the need for point-of-care testing (POCT) devices using test clusters that specifically detect pathogens...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：10.1016/j.cll.2009.07.014
更新日期：2009-09-01 00:00:00
abstract：:Susceptibility testing of microorganisms isolated from blood cultures should follow the guidelines of the NCCLS in the selection of antimicrobial agents and the method for testing. Standardized testing can be performed on isolated colonies from pure subcultures of the blood/broth mixture. Direct susceptibility testing...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1994-03-01 00:00:00
abstract：:Recent studies have brought remarkable progress in the understanding of cellular, subcellular, and molecular mechanisms of endothelial injury and responses to injury, both of which appear to be integral parts of the acute inflammatory response. The possible roles of endothelial surface enzymes in the inflammatory resp...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1983-12-01 00:00:00
abstract：:With emerging antimicrobial resistance, rapid antimicrobial susceptibility testing (AST) is needed to provide early definitive therapeutic guidance to optimize patient outcome. Genotypic methods are fast, but can identify only a subset of known resistance elements. Phenotypic methods determine clinically predictive mi...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2019.04.001
更新日期：2019-09-01 00:00:00
abstract：:This article reviews cytomorphology of rare malignant tumors of the breast: squamous carcinoma, metaplastic carcinoma, adenoid cystic carcinoma, apocrine carcinoma, secretory carcinoma, lipid-rich carcinoma, and carcinoma with choriocarcinomatous features. It is important to bear in mind the cytomorphology and diagnos...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2005.08.004
更新日期：2005-12-01 00:00:00
abstract：:Control of human immunodeficiency virus type-1 (HIV-1) infection is the foremost public health challenge at the turn of the millennium. Two decades, 22 million fatalities, and 40 million living victims after its discovery, HIV-1 continues its inexorable spread. Over the past few years, scientists have made tremendous ...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：10.1016/s0272-2712(02)00020-3
更新日期：2002-12-01 00:00:00
abstract：:Acute accidental iron poisoning is a common serious and potentially fatal intoxication in the young child. Approximately 1 per cent of such poisoning have a fatal outcome, and outcome is closely related to the early onset of coma or shock. Long-term prognosis is excellent for all survivors of the acute episode, althou...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：:"Bath salts" has attracted young adults primarily due to its stimulatory and hallucinogenic effects akin to amphetamines and cocaine. Although other designer amines have been incorporated to newer generation "bath salts", synthetic cathinones remain to be their major component. This article discusses our current under...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2012.07.010
更新日期：2012-09-01 00:00:00
abstract：:This study uses three unique data sets to show the state of the art of hemoglobin A1c (HbA1c) analyzers in a range of settings and compares their performance against the international guidance set by the International Federation of Clinical Chemistry and Laboratory Medicine task force for HbA1c standardization. The da...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2016.09.006
更新日期：2017-03-01 00:00:00
abstract：:The active management of laboratory test utilization appears to be a practical approach to addressing the financial pressures imposed by managed care and capitated reimbursement, and can complement efforts already underway in most laboratories to reduce the unit cost of testing. Managing laboratory utilization takes t...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:Yellow fever (YF) is a viral disease, endemic to tropical regions of Africa and the Americas, which principally affects humans and nonhuman primates and is transmitted via the bite of infected mosquitoes. Yellow fever virus (YFV) can cause devastating epidemics of potentially fatal, hemorrhagic disease. Despite mass v...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2010.01.001
更新日期：2010-03-01 00:00:00
abstract：:Screening tests may help or harm the healthy subject and, therefore, must be selected and used carefully. Criteria for selection include characteristics of the disease(s), of the potential screening tests, and of the population(s) to be screened. An understanding of methods used to evaluate tests will allow the invest...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1986-06-01 00:00:00
abstract：:Seven different mycoplasmas have been isolated from the human genitourinary tract. The diseases they cause or with which they have been associated are described. Diagnosis of infection by cultural and noncultural (antigen detection, DNA probes) methods is discussed in detail. The more useful serologic procedures are i...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1989-09-01 00:00:00
abstract：:From the inception of TBS in 1988, it has been well received by the pathology and clinical communities. The need for a unifying system of nomenclature was so great that most of the laboratories in the United States, as well as in numerous countries worldwide, quickly adopted TBS. By 1991, only 2 years after the initia...
journal_title：Clinics in laboratory medicine
pub_type： 共识发展会议,杂志文章,评审
doi：10.1016/s0272-2712(03)00053-2
更新日期：2003-09-01 00:00:00
abstract：:Several major pet-food and human-food safety incidents occurred worldwide between 2003 and 2008, causing illnesses and deaths in children, cats, dogs, and pigs. During the 2007 outbreak of renal failure in dogs and cats in the United States, veterinary diagnostic laboratories helped identify melamine and melamine anal...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：10.1016/j.cll.2010.10.003
更新日期：2011-03-01 00:00:00
abstract：:Fine needle aspiration biopsy (FNAB) is the diagnostic procedure of choice for evaluation of liver lesions. Although primarily applied to malignant disease, it is also used in the evaluation of benign conditions. Improvements in imaging techniques and advances in cytologic interpretations, as well as production of new...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1998-09-01 00:00:00
abstract：:Rapidly changing technology in the clinical microbiology laboratory requires a highly skilled workforce. The current clinical microbiology workforce is aging with a wave of retirements currently unfolding. Key competencies that will be needed for the next generation of microbiologists include strong analytical skills,...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2019.05.007
更新日期：2019-09-01 00:00:00
abstract：:This study examines the relationship between D-dimer concentration and patient age, gender, race, and renal function, and the role of D-dimer concentration as a predictor of in-hospital mortality, in a critically ill patient population. The results demonstrate there is a correlation between increased D-dimer concentra...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2014.06.015
更新日期：2014-09-01 00:00:00
abstract：:To overcome the significant mortality associated with ovarian cancer, a highly sensitive and specific screening test is urgently needed. CA-125 testing is used to monitor response to chemotherapy, detect recurrence, and detect late stage ovarian cancer. However, CA-125 testing, alone or in combination with ultrasonogr...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2009.02.001
更新日期：2009-03-01 00:00:00
abstract：:Transfusion medicine is a rapidly evolving specialty, and efforts are ongoing to improve the safety and quality of blood component therapy. Leukocytes are known to be the cause of numerous adverse effects of transfusion therapy, and their removal from red cells and platelet components may be desirable in a variety of ...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1992-12-01 00:00:00
abstract：:Lyme disease in North America is caused by infection with the spirochetal bacterium Borrelia burgdorferi and transmitted by Ixodes scapularis and Ixodes pacificus ticks. These ticks also have the potential to transmit a rapidly expanding list of other pathogenic bacteria, viruses, and parasites, including Anaplasma ph...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2015.07.006
更新日期：2015-12-01 00:00:00
abstract：:A methodology for computing the maximum expected number of unreliable patient results produced because of an out-of-control condition for a given quality control strategy is presented along with strategies for changing the expected number of unreliable results produced and reported. The expected number of unreliable p...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：10.1016/j.cll.2012.11.006
更新日期：2013-03-01 00:00:00
abstract：:Automation of AST has come quite some way and is here to stay. In particular, fully automated, "hands off" instruments have great appeal to laboratories with a limited number of well-trained and experienced clinical microbiology personnel. None of the evaluated instruments is perfect, but then neither are the standard...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:The clinical application of B- and T-cell gene rearrangement analysis is discussed relative to diagnostic problems in specific lymphoproliferative disorders. This article reviews the use of the Southern blot hybridization technique for B- and T-cell gene rearrangement detection in the analysis of various hematopoietic...
journal_title：Clinics in laboratory medicine
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
