Rapid Susceptibility Testing Methods.

Abstract:

:With emerging antimicrobial resistance, rapid antimicrobial susceptibility testing (AST) is needed to provide early definitive therapeutic guidance to optimize patient outcome. Genotypic methods are fast, but can identify only a subset of known resistance elements. Phenotypic methods determine clinically predictive minimal inhibitory concentrations and include very sensitive optical and biophysical methods to detect changes in replication or physiology of pathogens in response to antibiotics. For the potential of rapid AST to be fully realized, results must be linked with robust decision support solutions that will implement therapeutic changes in real time.

journal_name

Clin Lab Med

authors

Smith KP,Kirby JE

doi

10.1016/j.cll.2019.04.001

subject

Has Abstract

pub_date

2019-09-01 00:00:00

pages

333-344

issue

3

eissn

0272-2712

issn

1557-9832

pii

S0272-2712(19)30026-5

journal_volume

39

pub_type

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