Validating the performance of QC procedures.

abstract：:Clinical decision support (CDS) can greatly enhance patient blood management through optimizing ordering and providing patient-specific information. At present, modeling and prediction have small roles in inventory management; they will likely have increasing applications to help guide donor center collections based o...

journal_title：Clinics in laboratory medicine

authors： Shah NK

更新日期：2019-06-01 00:00:00

abstract：:To answer the question of whether reference values are useful in clinical decision-making, this article addresses the following major controversies: (1) Are reference subjects representative of the group from which they are selected? (2) To what extent should the process of collecting reference values be standardized ...

journal_title：Clinics in laboratory medicine

authors： Statland BE,Winkel P

更新日期：1984-03-01 00:00:00

abstract：:This article attempts to define and identify sources of variation in laboratory analysis that occur predominantly "away" from the analytic bench. Problems in the derivation and application of reference ranges are reviewed and sources of non-analytic error are "located" within the entire testing cycle. Reference source...

journal_title：Clinics in laboratory medicine

authors： Bachner P

更新日期：1986-12-01 00:00:00

abstract：:The primary product of the laboratory is information. Greater attention should be devoted to how laboratory reports are presented to ensure that information is being conveyed effectively to the clinician. Different reporting techniques, including test-by-test, interim, cumulative, and completed accession reports, are ...

journal_title：Clinics in laboratory medicine

authors： Aller RD

更新日期：1991-03-01 00:00:00

abstract：:Pet guinea pigs are presented to veterinary clinics for routine care and treatment of clinical diseases. In addition to obtaining clinical history and exam findings, diagnostic testing may be required, including hematological assessments. This article describes common blood collection methods, including venipuncture s...

journal_title：Clinics in laboratory medicine

authors： Zimmerman K,Moore DM,Smith SA

更新日期：2015-09-01 00:00:00

abstract：:Recent studies have brought remarkable progress in the understanding of cellular, subcellular, and molecular mechanisms of endothelial injury and responses to injury, both of which appear to be integral parts of the acute inflammatory response. The possible roles of endothelial surface enzymes in the inflammatory resp...

journal_title：Clinics in laboratory medicine

authors： Ryan US,Ryan JW

更新日期：1983-12-01 00:00:00

abstract：:Technical advances in laboratory testing such as sensitive chemical tests and standardized commercial slides have significantly altered our entire approach to urinalysis. In addition, the recognition of the association of microhematuria with urologic neoplasms and the morphologically altered red blood cells with renal...

journal_title：Clinics in laboratory medicine

authors： Shenoy UA

更新日期：1985-06-01 00:00:00

abstract：:In marked contrast to their historical classification as relatively harmless, common cold-causing, respiratory pathogens, human coronaviruses (HCoVs) are associated with more severe clinical complications, as emphasized by the discovery of severe acute respiratory syndrome-associated CoV (SARS-CoV) in 2003. Still, the...

journal_title：Clinics in laboratory medicine

authors： Wevers BA,van der Hoek L

更新日期：2009-12-01 00:00:00

abstract：:The pathologist, by virtue of his or her observations and documentation of injuries with concomitant attempts to discern patterns of injury and correlate autopsy findings with investigative details, will often play an integral and primary role in the death investigation process. The information gleaned during this pro...

journal_title：Clinics in laboratory medicine

authors： Davis GJ

更新日期：1998-06-01 00:00:00

abstract：:"Bath salts" has attracted young adults primarily due to its stimulatory and hallucinogenic effects akin to amphetamines and cocaine. Although other designer amines have been incorporated to newer generation "bath salts", synthetic cathinones remain to be their major component. This article discusses our current under...

journal_title：Clinics in laboratory medicine

authors： Gerona RR,Wu AH

更新日期：2012-09-01 00:00:00

abstract：:Objective evidence-based national surveys serve as a first step in identifying suitable point-of-care device designs, effective test clusters, and environmental operating conditions. Preliminary survey results show the need for point-of-care testing (POCT) devices using test clusters that specifically detect pathogens...

journal_title：Clinics in laboratory medicine

authors： Kost GJ,Hale KN,Brock TK,Louie RF,Gentile NL,Kitano TK,Tran NK

更新日期：2009-09-01 00:00:00

abstract：:Modern advances in the diagnosis and treatment of the leukemias and lymphomas make use of dynamic techniques in immunology, genetics, and molecular biology, and, as a result, morphology represents a smaller proportion of the total diagnostic work-up of these diseases today than heretofore. However, morphology still re...

journal_title：Clinics in laboratory medicine

authors： Dickersin GR

更新日期：1987-03-01 00:00:00

abstract：:Direct-to-consumer genetic testing came on the scene 2 decades ago as a means for allowing consumers to access their genetic information without the involvement of a physician or genetic counselor. Results are delivered directly to the consumer, often leading to misinterpretation and needless medical interventions or ...

journal_title：Clinics in laboratory medicine

authors： Dinulos MBP,Vallee SE

更新日期：2020-03-01 00:00:00

abstract：:This article reviews the concept of dysplasia and the distinguishing features of dysplastic nevi, including their premalignant potential, their biologic markers of tumor progression, and their reproducibly recognizable clinical and histologic characteristics. An additional emphasis is placed on describing gray zone m...

journal_title：Clinics in laboratory medicine

authors： Kim JC,Murphy GF

更新日期：2000-12-01 00:00:00

abstract：:Image processing has traveled to the lunar surface and back, finding its way into the clinical laboratory. Advances in digital computers have improved the technology of image analysis, resulting in a wide variety of medical applications. Offering improvements in turnaround time, standardized systems, increased precisi...

journal_title：Clinics in laboratory medicine

authors： Kisner HJ

更新日期：1988-12-01 00:00:00

abstract：:Point-of-care testing is an emerging specialty in laboratory medicine and has attracted considerable interest in the medical literature. This article presents a general overview of point-of-care testing including its history, menu, clinical utility, aspects of analytical performance, regulatory issues, and management ...

journal_title：Clinics in laboratory medicine

authors： Lee-Lewandrowski E,Lewandrowski K

更新日期：2001-06-01 00:00:00

abstract：:The antiphospholipid syndrome (APS) is an autoimmune disorder presenting with tissue injury in various organs attributed to large or small vessel thrombosis or, in some instances, possible nonthrombotic inflammatory mechanisms, associated with in vitro evidence of antibodies to certain proteins, or proteinphospholipid...

journal_title：Clinics in laboratory medicine

authors： Eby C

更新日期：2009-06-01 00:00:00

abstract：:Control of human immunodeficiency virus type-1 (HIV-1) infection is the foremost public health challenge at the turn of the millennium. Two decades, 22 million fatalities, and 40 million living victims after its discovery, HIV-1 continues its inexorable spread. Over the past few years, scientists have made tremendous ...

journal_title：Clinics in laboratory medicine

authors： Elizaga ML,McElrath MJ

更新日期：2002-12-01 00:00:00

abstract：:Recent developments in the surgical pathology of the vulva include updated classifications of non-neoplastic epithelial disorders and vulvar intraepithelial neoplasias. Several histologic variants of vulvar squamous cell carcinoma (SCC) with distinct clinicopathologic features have been described. The concept of super...

journal_title：Clinics in laboratory medicine

authors： Johnson TL

更新日期：1995-09-01 00:00:00

abstract：:Vertical auto profile (VAP) method is a direct single test for measuring comprehensive lipoprotein cholesterol profile. It is based on a well-established method of ultracentrifugation that uses vertical rotor and single density gradient spin. VAP provides cholesterol concentrations of total lipoprotein, high-density l...

journal_title：Clinics in laboratory medicine

authors： Kulkarni KR

更新日期：2006-12-01 00:00:00

abstract：:Extracellular vesicles (EVs) are membranous particles found in a variety of biofluids that encapsulate molecular information from the cell, which they originate from. This rich source of information that is easily obtained can then be mined to find diagnostic biomarkers. This article explores the current biological un...

journal_title：Clinics in laboratory medicine

authors： Strotman LN,Linder MW

更新日期：2016-09-01 00:00:00

abstract：:The recent development and clinical implementation of genomic microarrays has resulted in rapid and significant changes for postnatal studies in the field of cytogenetics. This article discusses the benefits and issues for the use of microarrays for prenatal genetic diagnosis. It includes sections on specimen processi...

journal_title：Clinics in laboratory medicine

authors： Lamb AN

更新日期：2011-12-01 00:00:00

abstract：:Certain serum autoantibodies serve as useful diagnostic markers in AiLD; however, the etiology and pathogenesis of AiLD remain unknown. Although AiLD is characterized by the presence of autoantibodies and other humoral immune abnormalities, there is significant evidence that cell-mediated immune mechanisms are critica...

journal_title：Clinics in laboratory medicine

authors： Bylund DJ,McHutchison J

更新日期：1997-09-01 00:00:00

abstract：:This second part of the review article compiles currently available information on the effects of lead poisoning. Also examined are the available options for assay, the procedures for collection of samples, and the available methods for the estimation of lead in the collected samples. ...

journal_title：Clinics in laboratory medicine

authors： Philip AT,Gerson B

更新日期：1994-09-01 00:00:00

abstract：:Cannabis, or marijuana, has been known and used as a drug for many thousands of years. Recent interest in drug abuse and detection has spurred the development of several methodologies for cannabinoid detection. These methods include immunoassays and chromatography. Laboratories routinely performing cannabinoid testing...

journal_title：Clinics in laboratory medicine

authors： King DL,Martel PA,O'Donnell CM

更新日期：1987-09-01 00:00:00

abstract：:Fine needle aspiration biopsy (FNAB) is the diagnostic procedure of choice for evaluation of liver lesions. Although primarily applied to malignant disease, it is also used in the evaluation of benign conditions. Improvements in imaging techniques and advances in cytologic interpretations, as well as production of new...

journal_title：Clinics in laboratory medicine

authors： Pitman MB

更新日期：1998-09-01 00:00:00

abstract：:Transfusion medicine is a rapidly evolving specialty, and efforts are ongoing to improve the safety and quality of blood component therapy. Leukocytes are known to be the cause of numerous adverse effects of transfusion therapy, and their removal from red cells and platelet components may be desirable in a variety of ...

journal_title：Clinics in laboratory medicine

authors： Klapper EB,Goldfinger D

更新日期：1992-12-01 00:00:00

abstract：:Transgenic mice that contain a proline to leucine mutation at amino acid 101 in the endogenous murine PrP gene have been produced by gene targeting. This line of mice was generated to model the mutation thought to be responsible for P102L GSS, a familial TSE disease in humans. Genetargeted 101LL mice showed no evidenc...

journal_title：Clinics in laboratory medicine

authors： Barron RM,Manson JC

更新日期：2003-03-01 00:00:00

abstract：:Standard business inventory procedures can be cost effective when they are adapted to hospital laboratory inventory management in a 500-bed hospital. The investment in a central laboratory store-room and one additional employee yields financial benefits and indirect service benefits. The system requires consistent use...

journal_title：Clinics in laboratory medicine

authors： Weinstein W,Wenk RE

更新日期：1985-12-01 00:00:00

abstract：:From the inception of TBS in 1988, it has been well received by the pathology and clinical communities. The need for a unifying system of nomenclature was so great that most of the laboratories in the United States, as well as in numerous countries worldwide, quickly adopted TBS. By 1991, only 2 years after the initia...

journal_title：Clinics in laboratory medicine

authors： Henry MR

更新日期：2003-09-01 00:00:00