Abstract:
:We investigated the segregation of an intracellular microsporidian parasite during host cell division. A time-course experiment was carried out to examine the distribution of parasites relative to host chromosomal DNA via light and electron microscopy. Fluorescent light microscopy and EM studies showed that the parasite lay in the perinuclear zone of the host cell during interphase and segregated to daughter cells at mitosis. At metaphase, the parasite was frequently closely associated with host microtubules and mitochondria. Electron-dense bridges were observed between the parasites and the host microtubules and also between host mitochondria and microtubules. The study suggests that both the parasite and the host cell organelles segregate in association with spindle microtubules.
journal_name
Parasitologyjournal_title
Parasitologyauthors
Terry RS,Dunn AM,Smith JEdoi
10.1017/s0031182098003540subject
Has Abstractpub_date
1999-01-01 00:00:00pages
43-8eissn
0031-1820issn
1469-8161journal_volume
118 ( Pt 1)pub_type
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