Segregation of a microsporidian parasite during host cell mitosis.

Abstract:

:We investigated the segregation of an intracellular microsporidian parasite during host cell division. A time-course experiment was carried out to examine the distribution of parasites relative to host chromosomal DNA via light and electron microscopy. Fluorescent light microscopy and EM studies showed that the parasite lay in the perinuclear zone of the host cell during interphase and segregated to daughter cells at mitosis. At metaphase, the parasite was frequently closely associated with host microtubules and mitochondria. Electron-dense bridges were observed between the parasites and the host microtubules and also between host mitochondria and microtubules. The study suggests that both the parasite and the host cell organelles segregate in association with spindle microtubules.

journal_name

Parasitology

journal_title

Parasitology

authors

Terry RS,Dunn AM,Smith JE

doi

10.1017/s0031182098003540

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

43-8

eissn

0031-1820

issn

1469-8161

journal_volume

118 ( Pt 1)

pub_type

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