Abstract:
BACKGROUND:Previous studies reporting cortisol hyposecretion in chronic fatigue syndrome may have been confounded by venepuncture, fasting and hospitalisation. METHODS:Morning and evening salivary cortisol were obtained on consecutive days in the first 3 days of the menstrual cycle and compared in three samples of women taking no medication and matched for age: 14 patients with chronic fatigue syndrome, 26 community cases of ICD-10 current depressive episodes and 131 healthy community controls. RESULTS:The mean evening cortisol was significantly lower in the chronic fatigue syndrome patients compared to controls with depression (P = 0.02) and healthy controls (P = 0.005). Chronic fatigue syndrome patients without psychiatric disorder had significantly lower morning salivary cortisols compared to controls (P = 0.009). CONCLUSION:Chronic fatigue syndrome patients display cortisol hyposecretion in saliva as well as plasma compared to patients with depression and healthy controls. LIMITATIONS:Small samples of female patients with cortisol estimated at only two time points in the day. Cortisol secretion may be secondary to other neurotransmitter abnormalities or other physiological or lifestyle factors in chronic fatigue syndrome patients. CLINICAL RELEVANCE:Chronic fatigue syndrome is biochemically distinct from community depression.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Strickland P,Morriss R,Wearden A,Deakin Bdoi
10.1016/s0165-0327(97)00134-1subject
Has Abstractpub_date
1998-01-01 00:00:00pages
191-4issue
1-3eissn
0165-0327issn
1573-2517pii
S0165-0327(97)00134-1journal_volume
47pub_type
杂志文章abstract:BACKGROUND:Depression is the most common psychiatric disorder in deliberate self-harm (DSH) patients and in those who commit suicide. The aim of this study was to examine the treatment received by DSH patients with depression and their progress following DSH. METHODS:A representative sample of 106 patients with an ICD...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(01)00317-2
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Sleep spindles are believed to mediate several sleep-related functions including maintaining disconnection from the external environment during sleep, cortical development, and sleep-dependent memory consolidation. Prior studies that have examined sleep spindles in major depressive disorder (MDD) have not de...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.06.016
更新日期:2013-03-20 00:00:00
abstract::To compare mortality in bipolar and unipolar manic-depressive patients, 2168 manic-depressive first admissions reported to the Danish Psychiatric Central Register were divided into a bipolar group (19%), i.e., patients with at least one admission for mania during an average observation period of six years, and a unipo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(86)90074-1
更新日期:1986-11-01 00:00:00
abstract::The density of platelet 3H-imipramine binding sites (Bmax) was investigated in seven inpatients with winter depression before and after incandescent light treatment and in seven healthy volunteers within a 7-day interval without light exposure. A significantly lower mean Bmax value was found in the depressed patients ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90065-7
更新日期:1989-03-01 00:00:00
abstract::Thirty-eight patients with seasonal affective disorder (SAD) were compared with 33 non-seasonal recurrent major depressives (non-SAD) who presented during the winter months for differences in the prevalence of concurrent anxiety disorders and the impact of anxiety on treatment response. SAD patients received light the...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(93)90076-v
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Studies suggest that differentiating melancholic from non-melancholic depressive disorders is advanced by use of illness course as well as symptom variables but, in practice, potentially differentiating variables are generally positioned as having equal value. Judging that differentiating features are more l...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.03.057
更新日期:2015-07-15 00:00:00
abstract:BACKGROUND:Although psychological distress is common among patients with chronic diseases, the degree of risk for developing psychological distress is not well-established. Our aim with this study is to determine the odds ratio for psychological distress in patients with cancer as compared to either 1) patients with ch...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.11.089
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:Poor quality of life, sleep problems, anhedonia, and negative metacognitions are common in anxiety and depression. To examine the nature of the relationship between these features and the role of metacognitions, anhedonia, and quality of life in anxiety and depression, we conducted a complex network analysis...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.08.077
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND:Intermediate cognitive phenotypes (ICPs) are measurable and quantifiable states that may be objectively assessed in a standardized method, and can be integrated into association studies, including genetic, biochemical, clinical, and imaging based correlates. The present study used neuropsychological measures...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.08.018
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:COVID-19 is fast-spreading and potentially fatal, introducing home quarantine, social distancing, and increased internet usage globally. We investigated COVID-19 anxiety, general anxiety and depression symptoms, and their impact on problematic smartphone use (PSU) severity METHODS: Participants were 908 resi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.05.080
更新日期:2020-09-01 00:00:00
abstract::We measured plasma free HVA and MHPG in 39 cases of psychosis or mania judged to be caused by antidepressant exacerbation of symptoms. A total of 24 of patients had been receiving selective serotonin reuptake inhibitors (SSRI's). The SSRI group showed a pattern of increased plasma HVA similar to a comparison group of ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00327-x
更新日期:2002-04-01 00:00:00
abstract::Several concepts of minor depression in the sense of acute but less severe symptomatology than major depression have been proposed in the literature, but currently none of them is generally accepted. For the treatment of these conditions, only few recommendations based on empirical data are available. We conducted a r...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/s0165-0327(97)00072-4
更新日期:1997-09-01 00:00:00
abstract::The frequency of occurrence of prepubertal mania is contingent on how much adherence to episodic disorder with separate periods of mania and depression is required. While manic symptoms superimposed on other psychiatric disorders is not uncommon, non-comorbid bipolar disorder is rare. A number of developmental, phenom...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(98)00179-7
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Recent trials have demonstrated clinically meaningful efficacy and minimal cognitive side effects with ultrabrief pulsewidth right unilateral (RUL) ECT. In many countries it is gradually being adopted into clinical practice and further information on predictors of response is needed. METHODS:Data collected ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.09.016
更新日期:2011-04-01 00:00:00
abstract:OBJECTIVE:About 30% of patients with bipolar disorders (BD) exhibit a continuous cycling course (CCC). These patients significantly differ from those with non-continuous cycling course (NCCC) on clinical presentation and have a poorer short-term response to antidepressant treatment. Our aim is to conduct a meta-analysi...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2018.08.067
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Misophonia is a psychiatric disorder in which ordinary human sounds like smacking or chewing provoke intense anger and disgust. Despite the high burden of this condition, to date there is no evidence-based treatment available. In this study we evaluated the efficacy of cognitive behavioral therapy (CBT) and ...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/j.jad.2017.04.017
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Dissociative symptoms are often seen in patients with mood disorders, but there is little information on possible association with subgroups and temperamental features of these disorders. METHODS:The Dissociative Experience Scale was administered to 85 patients with a DSM-IV Major Depressive Disorder (MDD) ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.10.018
更新日期:2008-06-01 00:00:00
abstract:INTRODUCTION:Tonic immobility is the last defense against predation in animals and is characterized by paralysis and analgesia. In humans, it has only been reported in women victims of sexual abuse. OBJECTIVE:This study evaluated the prevalence of peritraumatic tonic immobility (PTI) in patients with PTSD and investig...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.07.015
更新日期:2008-04-01 00:00:00
abstract::Twenty inpatients suffering from an adjustment disorder with depressed mood according to the DSM-III criteria were compared with 22 inpatients with a (situationally provoked) major depression without an additional DSM-III/axis I diagnosis, with regard to expert- and self-rated symptomatology, social dysfunction and pe...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90004-9
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:Two recent studies conducted in the US and in France found an unexpectedly high prevalence of a positive screen for bipolar disorder (BD) in primary care (PC). There are few studies of the prevalence of BD in PC and no information exists on the epidemiology of BD in Brazilian PC services. This study investig...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.05.040
更新日期:2012-12-20 00:00:00
abstract:BACKGROUND:Although genetic influences on bipolar I disorder are well established, localization of genes that predispose to the illness has been difficult. Some genes predisposing to bipolar I disorder may be transmitted without expression of the categorical clinical phenotype. One strategy to overcome this obstacle is...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.07.017
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Major Depressive Disorder (MDD) is the 3rd source for burden worldwide according to the World Health Organization (WHO). This comes partly from unsatisfactory response rates after usual treatment, highlighting the need for early indicators such as early improvement of depressive symptoms to adapt treatment s...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.03.002
更新日期:2014-06-01 00:00:00
abstract::The dexamethasone suppression test (DST), family history, response to antidepressant medication and short-term course were investigated in 16 female patients with masked depression. Twelve patients showed abnormal DST results, 3 patients had positive family history of affective illness in first-degree relatives, 11 re...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(83)90018-6
更新日期:1983-11-01 00:00:00
abstract:BACKGROUND:Existing systematic reviews provide evidence that music therapy is an effective intervention in the treatment of children and adolescents with psychopathology. The objective of the present review was to systematically review and quantify the effects of music-based interventions in reducing internalizing symp...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2017.08.035
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Bipolar disorder (BD) patients show morphological abnormalities in gray matter (GM) and white matter (WM), which can be revealed by structure MRI (sMRI) and diffusion tensor imaging (DTI) respectively. However, previous studies on BD mainly relied on separated analysis of single neuroimaging modality, and it...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.11.119
更新日期:2020-02-15 00:00:00
abstract:BACKGROUND:Although it is a well-known fact that migration is a risk factor contributing to psychopathology, little is known about how pre-migration factors may lead to depression among migrants. The present study examined the relationship between poorly planned migration and depressive symptoms, and evaluated the mode...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.06.005
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:This study investigates the rate of cerebral blood flow (rCBF) in Arab patients wth depression. METHODS:Forty-four patients with DSM-III-R major depressive disorders were studied at rest using single photon emission computerized tomography (SPECT) with 99m Tc-HMPAO in comparison with 20 normal controls. All...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(98)00209-2
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:The aim of this study was to explore the prospective relationship between depressive symptoms and anxiety across pregnancy and the early postpartum. METHODS:Participants (N=207) completed the State-Trait Anxiety Inventory Trait subscale, Beck Depression Inventory, and social support and sleep quality measur...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.06.002
更新日期:2009-03-01 00:00:00
abstract:INTRODUCTION:Recent studies have demonstrated that cortical brain areas tend to oscillate at a specific natural frequency when directly perturbed by transcranial magnetic stimulation (TMS). Fast electroencephalographic (EEG) oscillations, which typically originate from frontal regions, have been reported to be markedly...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.05.043
更新日期:2015-09-15 00:00:00
abstract:BACKGROUND:Bipolar psychopathology is characterized by affective dysregulation independent of mood episodes. However, previous research has relied on laboratory-based emotion-eliciting tasks or retrospective questionnaires that do not take into account temporal dynamics of affect. Thus, the present study examined affec...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.01.053
更新日期:2019-05-15 00:00:00