Deliberate self harm patients with depressive disorders: treatment and outcome.

Abstract:

BACKGROUND:Depression is the most common psychiatric disorder in deliberate self-harm (DSH) patients and in those who commit suicide. The aim of this study was to examine the treatment received by DSH patients with depression and their progress following DSH. METHODS:A representative sample of 106 patients with an ICD-10 depressive episode who presented to a general hospital following an episode of DSH were investigated in terms of their treatment before and after the episode and their outcome at follow-up. RESULTS:Prior to the index episode of DSH, 39 patients (36.8%) were receiving treatment from the psychiatric services and a further 35 (33.0%) were receiving treatment for mental health problems from their general practitioner. Fifty-two patients (49.1%) were receiving antidepressants (in therapeutic dosages in 93.6%). After the episode of DSH 94 patients (88.7%) were offered treatment with the psychiatric services, either as a new referral or continuation of treatment they were receiving prior to DSH. Of the patients who were followed-up, 36.3% remained in contact with the psychiatric services, 52.3% showed poor compliance with recommended treatment and 60.2% no longer fulfilled the diagnostic criteria for depression. Almost one-third reported a further episode of DSH during the follow-up period. LIMITATIONS:The nature and quality of non-physical treatments provided by the psychiatric services was not investigated. Reports of the treatment provided by general practitioners, the timing of improvement in symptoms and compliance with treatment largely relied on patients' self report. CONCLUSIONS:All patients presenting following DSH need to be carefully screened for depressive illness. Randomised controlled studies need to be conducted on DSH patients with depression to determine which treatments are effective.

journal_name

J Affect Disord

authors

Haw C,Houston K,Townsend E,Hawton K

doi

10.1016/s0165-0327(01)00317-2

subject

Has Abstract

pub_date

2002-06-01 00:00:00

pages

57-65

issue

1

eissn

0165-0327

issn

1573-2517

pii

S0165032701003172

journal_volume

70

pub_type

杂志文章
  • Knowledge about affective disorders and outcome of depression.

    abstract:BACKGROUND:For affective disorders, imparting information about the illness has become standard treatment. Despite the great clinical relevance of knowledge about depression, few empirical studies on this subject have been carried out. The aim of the study was to identify the prognostic value of knowledge about affecti...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2007.02.010

    authors: Kronmüller KT,Victor D,Schenkenbach C,Postelnicu I,Backenstrass M,Schröder J,Mundt C

    更新日期:2007-12-01 00:00:00

  • Dysfunction of the cingulo-opercular network in first-episode medication-naive patients with major depressive disorder.

    abstract:BACKGROUND:Major depressive disorder (MDD) is a common psychiatric disorder that may be associated with abnormal cognitive control and emotion regulation. Previous studies have found that network disconnection within the cingulo-opercular network (CON) plays an important role in psychiatric disorders and that the CON m...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2016.04.046

    authors: Wu X,Lin P,Yang J,Song H,Yang R,Yang J

    更新日期:2016-08-01 00:00:00

  • Life events in bipolar patients: a comparative study with siblings and healthy controls.

    abstract:BACKGROUND:While many studies have focused on life events in depressive disorders, data regarding them in bipolar disorder are scant. The aim of this work was to explore the characteristics of life events in bipolar patients. METHODS:Sixty bipolar patients have been included in our study. The evaluation focused on the...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.05.098

    authors: El Kissi Y,Krir MW,Ben Nasr S,Hamadou R,El Hedda R,Bannour S,Ben Hadj Ali B

    更新日期:2013-10-01 00:00:00

  • Anterior cingulate cortex, insula and amygdala seed-based whole brain resting-state functional connectivity differentiates bipolar from unipolar depression.

    abstract:OBJECTIVE:The frontal-limbic circuit is hypothesized as sub-serving emotional regulation. We performed whole brain resting-state functional connectivity (rs-FC) analysis by studying the key hubs of frontal-limbic circuit: anterior cingulate cortex (ACC), bilateral insula subregions, bilateral amygdala (Amy) as seeds, s...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.05.005

    authors: Yu H,Li ML,Li YF,Li XJ,Meng Y,Liang S,Li Z,Guo W,Wang Q,Deng W,Ma X,Coid J,Li DT

    更新日期:2020-09-01 00:00:00

  • One year clinical and psychosocial outcomes of early-onset chronic depression.

    abstract:BACKGROUND:Results from short-term treatment studies have demonstrated the efficacy of antidepressant medications for outpatients with early-onset chronic depression. However, scant data exists regarding the long-term outcome of these patients treated for this disorder. METHODS:The author conducted a one-year naturali...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0165-0327(98)00040-8

    authors: Agosti V

    更新日期:1999-07-01 00:00:00

  • Pro-inflammatory cytokines are elevated in adolescent females with emotional disorders not treated with SSRIs.

    abstract:BACKGROUND:Adults with major depressive disorder (MDD) show elevated levels of IL-6 and TNF-alpha. Studies of adolescents with MDD or anxiety disorders (AD) are few and present conflicting results. METHODS:We studied plasma cytokines in a clinical sample of adolescent females with MDD and/or clinical AD (n=60, mean ag...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2011.10.002

    authors: Henje Blom E,Lekander M,Ingvar M,Åsberg M,Mobarrez F,Serlachius E

    更新日期:2012-02-01 00:00:00

  • Comorbidity of PTSD and depression following myocardial infarction.

    abstract:BACKGROUND:This study examines comorbidity of posttraumatic stress disorder (PTSD) and depression following myocardial infarction (MI). It has two aims: (a) to examine whether this comorbidity is predicted by the objective severity of the MI and the patients' initial appraisal and stress responses; and (b) to determine...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2006.03.016

    authors: Ginzburg K

    更新日期:2006-08-01 00:00:00

  • Seasonality and bipolar disorder: a systematic review, from admission rates to seasonality of symptoms.

    abstract:INTRODUCTION:Bipolar disorder (BD) is a severe mental disorder affecting 1-4% of the population worldwide. It is characterized by periods of (hypo)manic and depressive episodes. Seasonal patterns (SP) may be observed in admission rates, mood relapses and symptom fluctuations. METHODS:We conducted a systematic review o...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2014.07.002

    authors: Geoffroy PA,Bellivier F,Scott J,Etain B

    更新日期:2014-10-01 00:00:00

  • Excessive daytime sleepiness in medical students of Hunan province: Prevalence, correlates, and its relationship with suicidal behaviors.

    abstract:BACKGROUND:Excessive daytime sleepiness (EDS) is common among medical students, but may have some serious consequences. This study aimed to investigate the prevalence and correlates of EDS among the medical students of Hunan Province, China. The correlation between EDS and suicidal ideation in our participants was also...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.05.036

    authors: Shen Y,Meng F,Tan SN,Zhang Y,Anderiescu EC,Abeysekera RE,Luo X,Zhang XY

    更新日期:2019-08-01 00:00:00

  • Mitochondrial inheritance in depression, dysmotility and migraine?

    abstract:BACKGROUND:Several studies have reported a high degree of association of the common conditions of depression, bowel dysmotility and migraine. Mitochondrial dysfunction and mitochondrial DNA (mtDNA) sequence variants have been linked individually to each of these three conditions, providing a plausible hypothesis for th...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2005.05.009

    authors: Burnett BB,Gardner A,Boles RG

    更新日期:2005-09-01 00:00:00

  • Association between metabolic syndrome and depressive symptom profiles--sex-specific?

    abstract:BACKGROUND:The association between depression and metabolic syndrome is becoming more obvious. Waist circumference (WC) might be the most important metabolic syndrome (MetS) feature in relation to late-life depression, with a possible mediating role for adiponectin. METHODS:Cross-sectional population based survey of 1...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.07.029

    authors: Marijnissen RM,Smits JE,Schoevers RA,van den Brink RH,Holewijn S,Franke B,de Graaf J,Oude Voshaar RC

    更新日期:2013-12-01 00:00:00

  • Meta-analytic review of the effects of a single dose of intranasal oxytocin on threat processing in humans.

    abstract:BACKGROUND:Heightened threat sensitivity is a transdiagnostic feature in several psychiatric disorders. The neuropeptide oxytocin has been shown to reduce fear related behaviours and facilitated fear extinction in animals. These findings have led to increasing interest to explore the effects of intranasal oxytocin on t...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jad.2017.08.041

    authors: Leppanen J,Ng KW,Kim YR,Tchanturia K,Treasure J

    更新日期:2018-01-01 00:00:00

  • Bupropion and paroxetine differentially influence cardiovascular and neuroendocrine responses to stress in depressed patients.

    abstract:BACKGROUND:There exists a need to identify safe and effective treatments for depression in patients with coronary heart disease (CHD). METHODS:Using a cross-sectional design, 17 depressed patients being treated with bupropion (200-450 mg/day) were compared with 17 depressed patients being treated with paroxetine (10-5...

    journal_title:Journal of affective disorders

    pub_type: 临床试验,杂志文章

    doi:10.1016/S0165-0327(02)00352-X

    authors: Straneva-Meuse PA,Light KC,Allen MT,Golding M,Girdler SS

    更新日期:2004-04-01 00:00:00

  • Mental disorders in cancer suicides.

    abstract::Mental disorders among suicide victims who had suffered from cancer were investigated using psychological autopsy data on all suicides in Finland over 1 year. Retrospective DSM-III-R consensus diagnoses were assigned to all 60 cancer suicides and to 60 age- and sex-matched comparison suicides without a cancer history....

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(95)00047-x

    authors: Henriksson MM,Isometsä ET,Hietanen PS,Aro HM,Lönnqvist JK

    更新日期:1995-12-24 00:00:00

  • Association of salivary cortisol levels and later depressive state in elderly people living in a rural community: a 3-year follow-up study.

    abstract:BACKGROUND:Late-life depressive disorder is becoming an important issue in health economics in the world, as it has been reported to be one of major risk factors for incidence of dementia. Identification of predictive markers associated with depression in later life is therefore of high priority in public health. The a...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.02.003

    authors: Nabeta H,Mizoguchi Y,Matsushima J,Imamura Y,Watanabe I,Tateishi T,Kojima N,Kawashima T,Yamada S,Monji A

    更新日期:2014-04-01 00:00:00

  • The role of somatic health problems in the recognition of depressive and anxiety disorders by general practitioners.

    abstract:BACKGROUND:Recognition of depression and anxiety by general practitioners (GPs) is suboptimal and there is uncertainty as to whether particular somatic health problems hinder or facilitate GP recognition. The objective of this study was to investigate the associations between somatic health problems and GP recognition ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.08.030

    authors: Gerrits MM,van Marwijk HW,van Oppen P,van der Horst H,Penninx BW

    更新日期:2013-12-01 00:00:00

  • 5-HTTLPR and gender differences in affective disorders: A systematic review.

    abstract:BACKGROUND:Serotonin transporter-linked polymorphic region (5-HTTLPR) variants have been extensively studied in psychiatric disorders. Although gender effects have been reported, they have not been comprehensively reviewed. The aim of our study was to summarize literature findings on 5-HTTLPR and gender differences in ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章,评审

    doi:10.1016/j.jad.2015.09.027

    authors: Gressier F,Calati R,Serretti A

    更新日期:2016-01-15 00:00:00

  • Depression and vulnerability to incident physical illness across 10 years.

    abstract:BACKGROUND:While considerable research exists on the role of physical illness in initiating depressive reactions, the role of depression in the onset of physical illness is much less studied. Moreover, whereas almost all previous research on depression and incident physical illness has involved specific physical illnes...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2009.10.006

    authors: Holahan CJ,Pahl SA,Cronkite RC,Holahan CK,North RJ,Moos RH

    更新日期:2010-06-01 00:00:00

  • Reliability and validity of the Beck Depression Inventory-Fast Screen for medical patients in the general German population.

    abstract:BACKGROUND:The Beck Depression Inventory Fast Screen (BDI-FS) is a self-report instrument for the detection of depression in youths and adults. It measures the severity of the depression, corresponding to the non-somatic criteria for the diagnosis of a major depression according to DSM-5. Until now the psychometric pro...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2013.11.024

    authors: Kliem S,Mößle T,Zenger M,Brähler E

    更新日期:2014-03-01 00:00:00

  • Association of maternal depression and home adversities with infant hypothalamic-pituitary-adrenal (HPA) axis biomarkers in rural Pakistan.

    abstract:BACKGROUND:Each year, almost 35% of children are exposed to maternal depression and more grow up in persistent poverty, increasing the risk for stress-related disease and other socio-developmental deficits later in life. These impacts are likely related to chronic stress via the hypothalamic-pituitary-adrenal (HPA) axi...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.07.053

    authors: Hagaman AK,Baranov V,Chung E,LeMasters K,Andrabi N,Bates LM,Rahman A,Sikander S,Turner E,Maselko J

    更新日期:2020-11-01 00:00:00

  • Chronobiologic parameter changes in patients with major depressive disorder and sleep disturbance treated with adjunctive brexpiprazole: An open-label, flexible-dose, exploratory substudy.

    abstract:BACKGROUND:Circadian rhythm disturbances have been reported in patients with major depressive disorder (MDD). Among these is an increased phase angle between peak cortisol concentration and dim-light melatonin onset (DLMO). The aim of this study was to evaluate changes in chronobiologic parameters of sleep in patients ...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.09.026

    authors: Krystal AD,Mittoux A,Lindsten A,Baker RA

    更新日期:2021-01-01 00:00:00

  • Gambling problems in treatment for affective disorders: Results from the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC).

    abstract:BACKGROUND:Gambling problems co-occur frequently with other psychiatric difficulties and may complicate treatment for affective disorders. This study evaluated the prevalence and correlates of gambling problems in a U. S. representative sample reporting treatment for mood problems or anxiety. METHODS:n=3007 respondent...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2016.05.023

    authors: Cowlishaw S,Hakes JK,Dowling NA

    更新日期:2016-09-15 00:00:00

  • Personality traits and depressive symptoms: The moderating and mediating effects of resilience in Chinese adolescents.

    abstract:BACKGROUND:Various studies showed that personality traits and resilience might have impacts on depressive symptoms, separately. However, the relationships among personality traits, resilience and depressive symptoms are still undefined. Thus, this study tried to explore the potential effect of resilience on the associa...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.11.102

    authors: Gong Y,Shi J,Ding H,Zhang M,Kang C,Wang K,Yu Y,Wei J,Wang S,Shao N,Han J

    更新日期:2020-03-15 00:00:00

  • 'The Button Question': A mixed-methods study of whether patients want to keep or remove bipolar disorder and the reasons for their decision.

    abstract:BACKGROUND:Many people with a diagnosis of bipolar disorder associate positive qualities with their condition, which may place a ceiling on the effectiveness of treatment and the likelihood of recovery. However, the extent to which patients would, or would not, want to be free of their bipolar disorder has not been dir...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2018.11.025

    authors: Folstad S,Mansell W

    更新日期:2019-02-15 00:00:00

  • Single-nucleotide polymorphism in the human TIA1 gene interacts with stressful life events to predict the development of pathological anxiety symptoms in a Swedish population.

    abstract:BACKGROUND:The TIA1 gene encodes a prion-related RNA-binding protein that regulates stress-dependent synaptic plasticity and fear memory in mice. It is unknown whether genetic variation in human TIA1 is associated with differences in stress- and fear-related behavior in people. METHODS:A longitudinal, population-based...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2019.09.018

    authors: Rayman JB,Melas PA,Schalling M,Forsell Y,Kandel ER,Lavebratt C

    更新日期:2020-01-01 00:00:00

  • Emotionally valenced stimuli impact response inhibition in those with substance use disorder and co-occurring anxiety and depression symptoms.

    abstract:BACKGROUND:Substance use disorder (SUD) is associated with impaired response inhibition. Given the deficits in emotion regulation associated with SUD, it is unclear if this impairment is exacerbated by emotionally valenced stimuli. Co-occurring conditions may further exacerbate these impairments as many co-occurring co...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.02.008

    authors: Legrand AC,Price M

    更新日期:2020-04-01 00:00:00

  • Lithium excessively enhances event related beta oscillations in patients with bipolar disorder.

    abstract:BACKGROUND:Previous resting-state electroencephalography studies have consistently shown that lithium enhances delta and theta oscillations in default mode networks. Cognitive task based networks differ from resting-state networks and this is the first study to investigate effects of lithium on evoked and event-related...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2014.08.024

    authors: Atagün Mİ,Güntekin B,Tan D,Tülay EE,Başar E

    更新日期:2015-01-01 00:00:00

  • A comparison of ECT dosing methods using a clinical sample.

    abstract:BACKGROUND:Several methods have been used to determine ECT dose based on formulae, protocols or fixed-dosing. This study aims to explore the relative utility of these ECT dosing methods. METHODS:A sample of ECT patients from Aberdeen was analysed. Seizure thresholds derived empirically were used to calculate the propo...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2012.02.033

    authors: Bennett DM,Perrin JS,Currie J,Blacklaw L,Kuriakose J,Rao A,Reid IC

    更新日期:2012-12-10 00:00:00

  • Evaluation of the effects of rTMS on self-reported quality of life and disability in treatment-resistant depression: A THREE-D study.

    abstract:INTRODUCTION:Although the antidepressant efficacy of rTMS is well documented, patient reported outcomes (PROs) with rTMS are poorly characterized. The aim of the current study is to assess short and long-term changes in self-reported quality of life and disability following a 6-week course of rTMS. METHODS:We performe...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/j.jad.2020.03.002

    authors: Giacobbe P,Mithani K,Meng Y,Vila-Rodriguez F,Daskalakis ZJ,Downar J,Blumberger DM

    更新日期:2020-05-01 00:00:00

  • The impact of an uncaring partner on improvement in non-melancholic depression.

    abstract::Interpersonal characteristics of the intimate partners of patients with non-melancholic depressive disorders were evaluated as potential predictors of outcome in an eighteen-month, longitudinal study. The short-term reduction in depressive symptoms was predicted most significantly by the patient's perception of the pa...

    journal_title:Journal of affective disorders

    pub_type: 杂志文章

    doi:10.1016/0165-0327(92)90077-j

    authors: Hickie I,Parker G

    更新日期:1992-06-01 00:00:00