Abstract:
OBJECTIVE:About 30% of patients with bipolar disorders (BD) exhibit a continuous cycling course (CCC). These patients significantly differ from those with non-continuous cycling course (NCCC) on clinical presentation and have a poorer short-term response to antidepressant treatment. Our aim is to conduct a meta-analysis of the studies comparing long-term treatment response in CCC and NCCC bipolar patients. METHOD:We conducted a systematic review of studies on patients with a diagnosis of bipolar disorder with CCC. Our primary outcome measure was the response to treatment at the last follow-up visit. The data analysis was based on the success rate difference as the effect size measure. To account for heterogeneity of primary studies, aggregation of results was based on a random-effects model. RESULTS:We included six observational studies comprising a total of 671 patients (CCC 29.4%, NCCC 70.6%). Overall, the response rate was 34.0% in the CCC and 49.3% in the NCCC arm. The meta-analysis shows a significant association between cycle pattern and response (success rate difference: -0.17; 95% CI: -0.25, -0.09; p < 0.0001), with low heterogeneity (χ2 (5 )= 5.16; I2 = 3%). CONCLUSION:In bipolar disorders, patients with CCC have a poorer response to prophylactic treatment compared with patients with NCCC.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Tundo A,De Crescenzo F,Gori D,Cavalieri Pdoi
10.1016/j.jad.2018.08.067subject
Has Abstractpub_date
2018-12-01 00:00:00pages
367-370eissn
0165-0327issn
1573-2517pii
S0165-0327(18)30834-6journal_volume
241pub_type
杂志文章,meta分析abstract:BACKGROUND:Default mode network (DMN) has been widely reported to be altered in bipolar disorder during major depressive episode (BDD). Recent studies supported the idea that DMN is not an unitary system, but composed of smaller and distinct functional subsystems. The current study aimed to investigate the abnormal fun...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.11.049
更新日期:2021-02-15 00:00:00
abstract::Since (a) obsessive-compulsive disorder (OCD) may involve serotonergic neural transmission abnormalities also though to be related to regulation of suicide and aggression, (b) comorbidity between OCD and depression is substantial, and (c) depression is a major risk factor for suicide, a comprehensive analysis of clini...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1016/0165-0327(92)90054-a
更新日期:1992-01-01 00:00:00
abstract::We used three rating scales to study diurnal variation of mood in 37 patients with major depressive disorder (17 drug-free patients and 20 treatment refractory patients on stable regimens of antidepressant medication). The three rating scales included global self-ratings administered twice a day; an itemized, prospect...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0165-0327(92)90016-y
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:Negative bias to sad emotional stimuli has repeatedly been identified as a cognitive feature of major depressive disorder, particularly in facial expression recognition. However, it is unknown how negative bias applies to facial expression recognition in individuals with depressive symptoms. METHODS:A total...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.07.034
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Acute administration of subanesthestic doses of intravenous ketamine have been shown to elicit a rapid antidepressant response in patients with treatment-resistant depression. However, it remains to be seen if repeated doses over a longer period of time will have the same effects. Here, we assess the long-te...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.10.015
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:This study aimed to validate the ability of frequently used self-assessment scales in Swedish child and adolescent psychiatric practice to differentiate between adolescent girls with manifest anxiety disorders and depression from those with less severe symptoms. METHODS:The receiver-operating characteristic...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.07.006
更新日期:2010-05-01 00:00:00
abstract:BACKGROUND:Suicide is a major global mental health problem among college students. The aim of the current study was to explore the association between the psychological strains of the strain theory of suicide and suicidal behaviors among college students. METHODS:Participants comprised 1912 college students (16-28 yea...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.08.042
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family and plays a critical role in growth, differentiation, maintenance and synaptic plasticity of neuronal systems. Previous studies have demonstrated lower serum BDNF concentrations in major depressive disorder (MDD), with con...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.06.041
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Cognitive Behavioral Social Rhythm Group Therapy (CBSRT) is a chronobiologically-informed group therapy designed to stabilize social rhythms in veterans with comorbid combat-related PTSD and major depressive disorder (MDD). This randomized controlled pilot trial is the first to examine feasibility and prelim...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.09.009
更新日期:2020-12-01 00:00:00
abstract:BACKGROUND AND OBJECTIVE:Coronavirus disease 2019 (COVID-19) is a new infectious disease with high transmissibility and morbidity. It has caused substantial mental distress to medical professionals. We aimed to compare the psychological impact of the COVID-19 outbreak between frontline and non-frontline medical workers...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.06.031
更新日期:2020-10-01 00:00:00
abstract:OBJECTIVE:This study examined measurement variance for Autism Spectrum Disorder (ASD) in the Spence Children's Anxiety Scale - Parent Form (SCAS-P; Spence, 1999). In addition, we developed and evaluated a new parent report measure for anxiety (Macquarie Anxiety Behavioural Scale; MABS). METHOD:The sample consisted of ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.06.076
更新日期:2020-11-01 00:00:00
abstract::In order to evaluate the possible effect of glucocorticoids as neuromodulators of the hypothalamic-pituitary-somatotropic system in depression, cortisol, growth hormone (GH), and insulin-like growth factor I (IGF-I) concentrations were studied before and after oral administration of 1 mg dexamethasone at 11 p.m. in 16...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(89)90018-9
更新日期:1989-07-01 00:00:00
abstract:BACKGROUND:Cognitive compromise is a common experience for patients with depression and other mood disorders. Depressed patients sustain deficits in working memory and attentional distortions in emotional processing and negative attention biases, which may contribute to maintaining their depressive state. METHODS:The ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.08.080
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Neurotrophins including brain-derived neurotropic factor (BDNF) are implicated in the pathogenesis of major depressive disorder (MDD). Yet, the roles of brain-specific BDNF-related miRNAs miR-132 and miR-124 are unclear. METHODS:We enrolled 45 treatment-free patients with MDD, 32 citalopram-treated patients...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.11.090
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Affective temperaments are presumed to underlie bipolar psychopathology. The TEMPS-A has been widely used to assess affective temperaments in clinical and non-clinical samples. Cross-sectional research supports the association of affective temperaments and mood psychopathology; however, longitudinal research...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.04.006
更新日期:2014-08-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.03.011
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:The 15-item version of the Geriatric Depression Scale (GDS-15) is widely employed to screen depression among elderly but little is known about the scale functioning in cognitively impaired individuals when compared to normal ones. The aim of the current study is to investigate Differential Item Functioning (...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.11.045
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Depression is associated with an increased risk of cardiovascular diseases (CVD) and cardiovascular mortality. We investigated to what extent subjective health status explained the apparent association between depressive symptoms and cardiovascular mortality in older European men. METHODS:Data were used fro...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.07.005
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Sleep spindles are believed to mediate several sleep-related functions including maintaining disconnection from the external environment during sleep, cortical development, and sleep-dependent memory consolidation. Prior studies that have examined sleep spindles in major depressive disorder (MDD) have not de...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.06.016
更新日期:2013-03-20 00:00:00
abstract:BACKGROUND:A strong association has been found between dysregulation of hypothalamic-pituitary-adrenal (HPA) axis and depression and bipolar disorder. Glucocorticoid receptor is one of the involved receptors and its gene has been recognized as a candidate gene for major depressive disorder and bipolar disorder. Therefo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.06.020
更新日期:2011-11-01 00:00:00
abstract::An increasing number of computerised transdiagnostic cognitive behavioural therapy programs (TD-cCBT) have been developed in the past decade, but there are no meta-analyses to explore the efficacy of these programs, nor moderators of the effects. The current meta-analysis focused on studies evaluating TD-cCBT interven...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2016.03.018
更新日期:2016-07-15 00:00:00
abstract::Twenty-nine women were obtained from two community-based facilities and administered the 10-item Edinburgh Postnatal Depression Scale (EDPS) in a computerised and 'pencil and paper' form. A high correlation (r = 0.98) was found between the two test types. The computerised test was found to be acceptable to all women i...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(91)90086-8
更新日期:1991-05-01 00:00:00
abstract::Thirteen patients with major depressive disorder, 25 patients with dysthymia and 12 healthy controls underwent ergopsychometric testing. The effect of self-paced and set-paced load on mood, vigilance and perseveration tendency was recorded. Within the clinical groups, various types of load seemed to result mainly in v...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(91)90095-a
更新日期:1991-10-01 00:00:00
abstract:BACKGROUND:Research suggests that screening for suicidality does not have iatrogenic effects; however, less is known regarding the impact of repeatedly screening for suicidal ideation among individuals with varying levels of exposure to these screenings. This staggered sequential study evaluated whether suicidal ideati...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.02.022
更新日期:2018-05-01 00:00:00
abstract:INTRODUCTION:Bipolar disorder (BD) is a severe mental disorder affecting 1-4% of the population worldwide. It is characterized by periods of (hypo)manic and depressive episodes. Seasonal patterns (SP) may be observed in admission rates, mood relapses and symptom fluctuations. METHODS:We conducted a systematic review o...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2014.07.002
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been reported in bipolar disorder (BD), but previous magnetic resonance imaging (MRI) studies of pituitary gland volume in BD have yielded inconsistent findings. In addition, the contribution of genetic factors to the pituitary changes in BD remains...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.12.002
更新日期:2010-08-01 00:00:00
abstract::Daytime plasma cortisol levels in four rapid cycling bipolar affective disorder patients were measured longitudinally over multiple affective episodes, and changes in levels with mood state assessed for each individual patient. While three of the four patients had, as expected, increased cortisol levels during depress...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(87)90054-1
更新日期:1987-01-01 00:00:00
abstract:BACKGROUND:Social anxiety disorder is fairly prevalent among alcohol abusing/dependent subjects. The objective of the present study was to investigate: (a) the incidence of social anxiety symptoms in inpatient alcoholics, (b) the effect of alcohol detoxification on these symptoms, and (c) whether a combined psychothera...
journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0165-0327(02)00094-0
更新日期:2003-09-01 00:00:00
abstract:BACKGROUND:High levels of public spending, rising costs of treatments and scarcity of mental health resources have intensified the need for information on the cost-effectiveness of interventions for depression. There have been few reviews that consider the cost-effectiveness of all treatments for depression together. ...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.jad.2004.10.003
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Structural imaging studies of patients suffering from depressive disorder have revealed reduced hippocampal volume in the majority of cases. The present study aimed specifically at investigating the hippocampal function in unipolar depression using functional magnetic resonance imaging (fMRI). METHODS:Eleve...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.03.003
更新日期:2009-12-01 00:00:00