Abstract:
:Thirteen patients with major depressive disorder, 25 patients with dysthymia and 12 healthy controls underwent ergopsychometric testing. The effect of self-paced and set-paced load on mood, vigilance and perseveration tendency was recorded. Within the clinical groups, various types of load seemed to result mainly in variations in mood. Dysthymics reacted to monotonous load with a deterioration in mood and reacted to load under time pressure with an improvement in mood. Patients with major depressive disorder displayed an amelioration in mood throughout the whole experiment regardless of which particular stressor was being employed. In healthy patients, load did not appear to produce any significant change in mood.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Günther V,Kryspin-Exner Idoi
10.1016/0165-0327(91)90095-asubject
Has Abstractpub_date
1991-10-01 00:00:00pages
81-92issue
2eissn
0165-0327issn
1573-2517pii
0165-0327(91)90095-Ajournal_volume
23pub_type
杂志文章abstract:BACKGROUND:Positive mental health (PMH) is an integral and essential component of health that encompasses emotional, psychological and social well-being. The Keyes' two continua model of mental health and illness posits that mental health status is not merely the absence of mental health problems, and it can be enhance...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.10.021
更新日期:2016-01-15 00:00:00
abstract:OBJECTIVE:Growing evidence supports the importance of psychological factors in the etiology and progression of cardiovascular disease (CVD). However, this research has been criticized due to overlap between psychological constructs. We examined whether psychological questionnaires frequently used in cardiovascular rese...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.05.017
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate whether uric acid levels are different between patients with remission period of bipolar disorder type I (BD) and patients with remission period of major depressive disorder (MDD). METHODS:For this aim 41 patients diagnosed with BD and 30 patients diagnosed with recu...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.04.053
更新日期:2014-08-01 00:00:00
abstract::This study investigated the effects of dexamethasone (1 mg orally) on the function of the hypothalamic-pituitary-thyroid (HPT) axis. We determined pre- and post-dexamethasone thyroid-secreting hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), reverse T3 and cortisol levels in 61 depressed inpatients. D...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/0165-0327(90)90049-e
更新日期:1990-09-01 00:00:00
abstract:BACKGROUND:Since the outbreak of 2019 new coronavirus (COVID-19) pneumonia, healthcare workers (HCW) have suffered psychological stress. The present study is to examine the prevalence of stress, anxiety and depression of HCW in China during the COVID-19 epidemic, and to determine the risk factors predicting psychologic...
journal_title:Journal of affective disorders
pub_type: 杂志文章,多中心研究
doi:10.1016/j.jad.2020.05.081
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Anecdotal reports of mood disorder following infection with common respiratory viruses with neurotropic potential have been in existence since the last century. Nevertheless, systematic studies on the association between these viruses and mood disorders are lacking. METHODS:Influenza A, B and coronavirus an...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.09.029
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:Little is known about gender differences in the costs and outcomes of primary care quality improvement strategies for depression. METHODS:Intent-to-treat analysis of data from a group-level controlled trial, in which matched primary care clinics in the US were randomized to usual care or to one of two inter...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2005.03.018
更新日期:2005-08-01 00:00:00
abstract:OBJECTIVE:About 30% of patients with bipolar disorders (BD) exhibit a continuous cycling course (CCC). These patients significantly differ from those with non-continuous cycling course (NCCC) on clinical presentation and have a poorer short-term response to antidepressant treatment. Our aim is to conduct a meta-analysi...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析
doi:10.1016/j.jad.2018.08.067
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Antidepressant medication (ADM) is thought to reduce depressive symptoms by altering emotion-generative brain systems. However, it is unknown whether successful ADM treatment is associated with changes in psychobehavioral strategies used to regulate emotions. We examined depressive symptoms and emotion regul...
journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2013.12.037
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Recent reports have suggested a relationship between affective disorder including depression and bipolar disorder (BP) and frontotemporal dementia (FTD). TAR DNA binding protein (TDP) -43 is a protein found in the brain and peripheral fluid of patients with FTD. To examine a possible association between affe...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.03.024
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Impulsivity is a key component of the manic behavior of bipolar disorder and is reported to occur in bipolar patients as a stable characteristic, i.e. a trait. Nevertheless, impulsivity has not been widely studied in depressed bipolar patients. We assessed impulsivity in depressed and euthymic bipolar and un...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2006.09.037
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Marital status is one of the most frequently replicated predictors of suicide. The purpose of this study was to examine the effect of marital status on the risk of suicide by gender, using a large population-based cohort in Japan. METHODS:The Miyagi cohort study was a population-based, prospective cohort st...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.05.006
更新日期:2013-09-25 00:00:00
abstract::Electrodermal hyporeactivity in the anticipation of aversive stimuli is a highly reliable correlate of diagnosed psychopathy and undersocialized aggressive conduct disorder (UACD), and it has been interpreted as reflecting a weak behavioral inhibition system (BIS) as conceptualized in Gray's work (e.g., in: Royce, J.R...
journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/s0165-0327(00)00336-0
更新日期:2000-12-01 00:00:00
abstract:BACKGROUND:Delayed diagnosis in bipolar disorder (BD) due to misdiagnosis as major depressive disorder (MDD) is a significant public health concern. Thus, identification of relevant diagnostic biomarkers is a critical unmet need, particularly early in the course of illness. The anterior cingulate cortex (ACC) is though...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.051
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The association between loneliness and suicide is poorly understood. We investigated how living alone, loneliness and emotional support were related to suicide and self-harm in a longitudinal design. METHODS:Between 2006 and 2010 UK Biobank recruited and assessed in detail over 0.5 million people in middle ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.10.026
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:The bipolar nature of unipolar depression with depressive mixed states (DMX) needs further validation studies. The seasonality of depressive episodes is indicated to be different between unipolar and bipolar depressions. We therefore explored the seasonal pattern of depressive episodes in unipolar depressive...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2005.09.009
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND:In this study we aimed to provide a global perspective of the association between different lifestyle behaviors and bullying in school adolescents and to ascertain whether or not the Human Development Index moderated those associations. METHODS:Data from the Global school-based Student Health Survey were an...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.04.065
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:Epidemiological and clinical studies have reported the frequent co-occurrence of social phobia (SP) and alcohol use disorders. Patients with SP often use alcohol to cope with the social situations they fear, and to lessen anticipatory anxiety, behavioral inhibition, and phobic avoidance. We investigated whet...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(00)00316-5
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Autism spectrum disorder (ASD), a prevalent developmental condition, is associated with comorbid mood disorders, most importantly depression. Here, we explored the underlying association between brain white matter microstructural integrity, assessed by diffusion tensor imaging (DTI), and depressive symptoms,...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.08.010
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Attention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent neurodevelopmental disorder in children and adults. Many ADHD patients experience affective symptoms that resemble the cyclothymic temperament trait, which is suggested to be a part of the bipolar spectrum. However, the relationship between adult...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.04.034
更新日期:2012-12-15 00:00:00
abstract:BACKGROUND:Many studies have demonstrated that major depression is related to an activation of the inflammatory response system (IRS) with an increased production of proinflammatory cytokines. It has been shown that tricyclic antidepressants and serotonin reuptake inhibitors suppress the activation of the IRS in depres...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(99)00076-2
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:Obsessive-compulsive disorder (OCD) is a chronic anxiety disorder of unknown aetiology. Psychopharmacological studies have suggested a role for the neurotransmitter serotonin however further evidence for serotonin in the aetiology of OCD is conflicted. The authors used positron emission tomography (PET) to e...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.06.020
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Depression and low-grade systemic inflammation are associated risk factors for hospitalizations and mortality, although the nature of this relationship is under-investigated. METHODS:We performed multivariable Cox regressions of first hospitalization/mortality for all and specific causes vs depression sever...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.10.004
更新日期:2021-01-15 00:00:00
abstract:BACKGROUND:The aim was to examine the prevalence and consequences of co-occurring insomnia and hypersomnia symptoms in depressed adults drawn from a representative sample of the U.S. population. METHOD:Data from 687 National Comorbidity Survey Replication (NCS-R) respondents meeting criteria for a major depressive epi...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.05.060
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Emotion dysregulation is prominent in generalized anxiety disorder (GAD), characterized clinically by exaggerated reactivity to negative stimuli and difficulty in down-regulating this response. Although limited research implicates frontolimbic disturbances in GAD, whether neural aberrations occur during emot...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.05.013
更新日期:2017-08-15 00:00:00
abstract:BACKGROUND:To study the association of manganese intake from diet with depressive symptoms in midlife women. METHODS:Data for this cross-sectional study were retrieved from baseline assessment of the Study of Women's Health Across the Nation (SWAN). Linear regression, logistic regression and restricted cubic spline mo...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2020.07.070
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Brain-derived neurotrophic factor (BDNF) is a member of the nerve growth factor family and plays a critical role in growth, differentiation, maintenance and synaptic plasticity of neuronal systems. Previous studies have demonstrated lower serum BDNF concentrations in major depressive disorder (MDD), with con...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2011.06.041
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Serotonin transporter promoter (5-HTTLPR) genotype appears to increase risk for depression in the context of stressful life events. However, the effects of this genotype on measures of stress sensitivity are poorly understood. Therefore, this study examined whether 5-HTTLPR genotype was associated with negat...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2007.07.028
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Rates of relapse and predictive relapse factors were studied over more than 4 years in a sample of Spanish outpatients with DSM-III-R criteria for unipolar major depressive episode. METHODS:A final sample of 139 outpatient was followed monthly in a naturalistic study. The Structured Clinical Interview for D...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2003.11.008
更新日期:2004-10-15 00:00:00
abstract:BACKGROUND:Deficits in social cognition, e.g. theory of mind (ToM) represent core characteristics involved in the etiology of psychopathological symptoms and an important predictor of social competence. In bipolar affective disorder, evidence for ToM deficits is scant, although brain imaging studies and impairments in ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.08.017
更新日期:2010-06-01 00:00:00